An update on prodrugs from natural products.

abstract：OBJECTIVE:To determine the range and incidence of complications associated with Plasmodium vivax (P. vivax) malaria. METHODS:A retrospective analysis was performed of all patients of P. vivax malaria admitted in Kasturba Medical College, Manipal between January and December, 2010. Patients with mixed malarial infectio...

journal_title：Asian Pacific journal of tropical medicine

authors： Naha K,Dasari S,Prabhu M

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To investigate the hepatoprotective and antioxidant activities of Alchornea cordifolia (A. cordifolia) leaf extract. METHODS:Various solvent fractions of the methanol extract of the leaf of the plant A. cordifolia Mull. Arg (Fam: Euphorbiaceae) were evaluated for hepatoprotective activity by carbon tetrachlo...

journal_title：Asian Pacific journal of tropical medicine

authors： Osadebe PO,Okoye FB,Uzor PF,Nnamani NR,Adiele IE,Obiano NC

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:To explore the value of B-ultrasound on the evaluation of the effects of traditional Chinese medicine compound of Radix astragali, Salvia miltiorrhiza and Angelica sinensis, and TCM + praziquantel on liver fibrosis in rabbits with schistosomiasis. METHODS:The hepatic fibrosis model in rabbits with schistosom...

journal_title：Asian Pacific journal of tropical medicine

authors： Liang XL,Yuan JY

更新日期：2013-08-01 00:00:00

abstract：:Brucellosis is a zoonotic disease characterized by reproductive failure in animals and undulent fever in humans. In cattle, it is caused by Brucella abortus while in goats by Brucella melitensis, the main cause of brucellosis in humans. Brucellosis in livestock has been associated with importation of animals from bree...

journal_title：Asian Pacific journal of tropical medicine

authors： Zamri-Saad M,Kamarudin MI

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To discuss the liver function damage mechanism of patients with clonorchiasis by analyzing the ultrasound characteristics, liver function, change of the serum inflammatory factors and cell apoptosis factors. METHODS:Color Doppler ultrasound technique was adopted to detect the portal vein and blood flow chang...

journal_title：Asian Pacific journal of tropical medicine

authors： Fan M,Lu L,Su C,Xue M,Dou JM,Li P,Feng HQ,Fan YB

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To investigate the feasibility of ultrasonic diagnosis for monitoring fracture healing. METHODS:Thirty rabbit models with fraction of mandible body were established by surgically removing partial lower jawbone. At the 1st, 2nd, 4th, 6th, 8th and 12th week after the operation, they were examined by X-ray and ...

journal_title：Asian Pacific journal of tropical medicine

authors： Chen T,Lai RF,Zhou ZY,Zhao QT,Yin ZD

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence and intensity of infection and the risk factors associated with urinary schistosomiasis in pre-school and school aged children in Guma Local Government Area of Benue State, Nigeria. METHODS:Urine filtration technique using polycarbonate membrane filters was employed to process uri...

journal_title：Asian Pacific journal of tropical medicine

authors： Amuta EU,Houmsou RS

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To compare the anti-atherosclerotic effects of two different extracts from the leaves of Mallotus furetianus by using rat model of atherosclerosis. METHODS:The air-dried powdered Mallotus furetianus leaves were extracted with ethanol and then evaporated. The ethanol extract was experienced Diaion HP-20 CC wi...

journal_title：Asian Pacific journal of tropical medicine

authors： Yueli L,Liqun W,Haitao W,Lianbo L,Xinan Y

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To screen for Escherichia coli (E. coli) resistant to tetracycline, followed by identification of tet efflux genes by polymerase chain reaction (PCR). In addition, detection of tetracycline residues in chicken livers and kidneys were conducted using high performance liquid chromatography-tandem quadrupole mas...

journal_title：Asian Pacific journal of tropical medicine

authors： S N AB,B M AM,A S AA,A E E,I Y M

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To study the expression of caveolin-1 in colorectal adenocarcinoma tissues and its correlation with microlymphatic vessel density (LMVD), and to investigate the clinical pathological prognostic significance of caveolin-1 and LMVD in patients with colorectal cancer. METHODS:The expression of caveolin-1 and LM...

journal_title：Asian Pacific journal of tropical medicine

authors： Xue J,Wu XL,Huang XT,Guo F,Yu HF,Zhang PC,Wang LK,Qu M,Pan LM

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of pomegranate peel aqueous extract (PGE) on the development of secondary experimental echinococcosis and on the viability of Echinococcus granulosus protoscoleces, and the immunomodulatory properties of PGE. METHODS:Swiss mice were inoculated intraperitoneally with viable protoscol...

journal_title：Asian Pacific journal of tropical medicine

authors： Labsi M,Khelifi L,Mezioug D,Soufli I,Touil-Boukoffa C

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To elucidates the immunoprophylactic potential of glutathion-s-transferase (GST) from cattle filarial parasite Setaria digitata (S. digitata) against lymphatic filariasis. METHODS:GST was purified through affinity chromatography (SdGST) and chacterized by SDS-PAGE and Nano-LC MS/MS analysis. Antibody isotype...

journal_title：Asian Pacific journal of tropical medicine

authors： Bal M,Mandal N,Achary KG,Das MK,Kar SK

更新日期：2011-03-01 00:00:00

abstract：:We present an atypical case of disseminated cutaneous leishmaniasis in the Sihuas district, located in the Andean valleys of Ancash-Peru. A 62-year-old man with no particular medical history presented multiple lesions located on the inferior abdomen, lumbar region and the right anterior thigh. Histological analysis fo...

journal_title：Asian Pacific journal of tropical medicine

authors： Espinoza-Morales D,Lucchetti Rodríguez A,Silva-Caso W,Suarez-Ognio L,Pons MJ,Del Valle Mendoza J

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of ischemic precondition to protect ischemia-reperfusion injury and reduce IL-6 expression in the rats liver transplantation. METHODS:The rat portal vein infusion of autologous liver transplantation model were used. The rats were divided into ischemic preconditioning rats liver tran...

journal_title：Asian Pacific journal of tropical medicine

authors： Cui LZ,Wang B,Chen LY,Zhou J

更新日期：2013-05-13 00:00:00

abstract：OBJECTIVE:To study the correlation of lipid ratios and individual lipid indexes of patients with type 2 diabetes with glycosylated hemoglobin (HbA(1c)). METHODS:Samples were collected from 128 type 2 diabetic patients (aged 19-90 years; male 72, female 56). The sera were analyzed for HbA(1c), total cholesterol (TC), t...

journal_title：Asian Pacific journal of tropical medicine

authors： Yan Z,Liu Y,Huang H

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To determine drug resistance mutations and the HIV-1 subtypes among antiretroviral treatment naive HIV-1 patients in Peninsular Malaysia. METHODS:A total of 45 samples from four hospitals that provide HIV viral load services were subjected to the amplification of the protease and two third of reverse transcr...

journal_title：Asian Pacific journal of tropical medicine

authors： Zain RM,Ibrahim N,Ismail S,Suppiah J,Mat Rahim NA,Thayan R

更新日期：2017-01-01 00:00:00

abstract：:Toxoplasmosis is a globally distributed parasitic protozoan disease, caused by Toxoplasma gondii. The infection can result in more severe symptoms with potentially life-threatening in case of immunocompromised individuals. Sulfadiazine and pyrimethamine are the two drugs used as a part of standard therapy for toxoplas...

journal_title：Asian Pacific journal of tropical medicine

authors： Al Nasr I,Ahmed F,Pullishery F,El-Ashram S,Ramaiah VV

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To demonstrate malaria situation analysis, stratification and planning for an endemic area in southern Iran. METHODS:Data on health system, population, meteorological parameters, malaria cases, anopheline vectors, and control activities during 2005-2007 was obtained from Minab Health Center, Minab Meteorolog...

journal_title：Asian Pacific journal of tropical medicine

authors： Hassan V,Arash R,Mehdi J,Ahmad R,Ali HB,Wali YA,Ali D,Abdulrasool M,Abbas P

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To investigate the protective role of Cardiospermum halicacabum (C. halicacabum) leaf extract on glycoprotein metabolism in streptozotocin (STZ)-induced diabetic rats. METHODS:Diabetes was induced in male albino Wistar rats by intraperitonial administration of STZ. The C. halicacabum leaf extract (CHE) was a...

journal_title：Asian Pacific journal of tropical medicine

authors： Veeramani C,Al-Numair KS,Alsaif MA,Chandramohan G,Al-Numair NS,Pugalendi KV

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To investigate the levels of serum cortisol in patients with uncomplicated Plasmodium falciparum (P. falciparum) malaria in an area of unstable malaria transmission in eastern Sudan. METHODS:The concentrations of cortisol were measured in sera of 25 patients with uncomplicated P. falciparum malaria (at prese...

journal_title：Asian Pacific journal of tropical medicine

authors： Ibrahim EA,Kheir MM,Elhardello OA,Almahi WA,Ali NI,Elbashir MI,Ishag A

更新日期：2011-02-01 00:00:00

abstract：:Captive reptiles, always more often present in domestic environment as pets, may harbor and excrete a large variety of zoonotic pathogens. Among them, Salmonella is the most well-known agent, whereas there are very scant data about infections by mycobacteria, chlamydiae and leptospirae in cold-blooded animals. However...

journal_title：Asian Pacific journal of tropical medicine

authors： Ebani VV

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To analyze the cytoprotective and antidiabetic activities as well as phytochemical composition of the immature inflorescence of Cocos nucifera belonging to the Arecaceae Family. METHODS:The phytochemical screening of inflorescence was done to determine the major constituents present in Cocos nucifera inflore...

journal_title：Asian Pacific journal of tropical medicine

authors： Renjith RS,Chikku AM,Rajamohan T

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To study the biocompatibility and neovascularization of the PLGA nanospheres wrapped with vascular endothelial growth factor (VEGF), which can improve bladder acellular matrix graft (BAMG) with local continuous release of VEGF. METHODS:A total of 18 rabbit model (length of stenosis: 3 cm) with anterior ureth...

journal_title：Asian Pacific journal of tropical medicine

authors： Wang JH,Xu YM,Fu Q,Song LJ,Li C,Zhang Q,Xie MK

更新日期：2013-06-01 00:00:00

abstract：:Harmony is defined as the pleasing combination of elements of a system to form an all-inclusive, all involving and more productive team. The aim of this present review was to investigate the factors militating against harmony among healthcare professional in the Nigerian healthcare delivery system. This review was car...

journal_title：Asian Pacific journal of tropical medicine

authors： Osaro E,Charles AT

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of Cannabis sativa resin and/or tramadol, two commonly drugs of abuse on acetylcholinesterase and butyrylcholinesterase activities as a possible cholinergic biomarkers of neurotoxicity induced by these agents. METHODS:Rats were treated with cannabis resin (5, 10 or 20 mg/kg) (equiva...

journal_title：Asian Pacific journal of tropical medicine

authors： Abdel-Salam OM,Youness ER,Khadrawy YA,Sleem AA

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To explore the regulatory role of thioredoxin-interacting protein (TXNIP) in Wnt/β-catenin signaling pathway and therefore to elucidate its function in diabetic myocardial infarction. METHODS:Diabetic myocardial infarction models were generated in mice. The expression levels of TXNIP and β-catenin and level ...

journal_title：Asian Pacific journal of tropical medicine

authors： Yu H,Zhao XX,Shan XH,Li P,Chen T

更新日期：2015-11-01 00:00:00

abstract：:Hookworm infection is a relatively common cause of anemia in endemic areas. The most common hookworm species are Ancylostoma duodenale and Necator americanus. In this report we present a case of overt gastrointestinal bleeding because of hookworm infection. Capsule endoscopy revealed many hookworms in the lumen of pro...

journal_title：Asian Pacific journal of tropical medicine

authors： Chen JM,Zhang XM,Wang LJ,Chen Y,Du Q,Cai JT

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:To build the rat model of gastric precancerous lesions and discuss the effect of transplantation of mesenchymal stem cells (BMMSCs) on the pathological change. METHODS:The rat model of gastric precancerous lesions was built using N-methyl-N'-nitro-N'-nitrosoguanidine. After the intravenous transplantation of...

journal_title：Asian Pacific journal of tropical medicine

authors： Lin ZL,Zheng GW,Zhang L,Zheng JT,Chen H

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To investigation the chemopreventive potential of Fumaria indica (F. indica) extract (FIE) on N-nitrosodiethylamine and CCl(4)-induced hepatocarcinogenesis in Wistar rats. METHODS:The experimental animals were divided into six groups (n=6). Hepatocellular carcinoma was induced by single intraperitoneal injec...

journal_title：Asian Pacific journal of tropical medicine

authors： Hussain T,Siddiqui HH,Fareed S,Vijayakumar M,Rao CV

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To identify the possible antiplasmodial compounds from leaf, stem, root and flower extracts of Ocimum canum (O. canum), Ocimum sanctum (O. sanctum) and Ocimum basilicum (O. basilicum). METHODS:The O. canum, O. sanctum and O. basilicum were collected from Ramanathapuram District, Tamil Nadu and the extraction...

journal_title：Asian Pacific journal of tropical medicine

authors： Inbaneson SJ,Sundaram R,Suganthi P

更新日期：2012-02-01 00:00:00