Susceptible mice present higher macrophage activation than resistant mice during infections with myotropic strains of Trypanosoma cruzi.

abstract：:Recent advances in molecular genetics and in imaging mean that it is now increasingly feasible to image biological processes within helminth parasites and to visualize interactions between worms and their hosts. Moreover, other innovative imaging approaches that are not dependent on transgenic parasites have been appl...

journal_title：Parasite immunology

authors： Pearce EJ,Lok JB

更新日期：2013-09-01 00:00:00

abstract：:Toxoplasma gondii is a worldwide protozoan parasite which causes severe disease in congenitally infected children and in immunocompromised patients. Besides the well-defined cytoplasmic and membrane antigens of tachyzoites, we felt that excreted/secreted antigens could play a major role in the immune response. We firs...

journal_title：Parasite immunology

authors： Darcy F,Deslee D,Santoro F,Charif H,Auriault C,Decoster A,Duquesne V,Capron A

更新日期：1988-09-01 00:00:00

abstract：:Schistosomiasis poses a serious threat to public health, and the infection will develop into chronic and advanced late-stage disease if not treated. Apart from the clinical signs due to immune reactions to schistosome eggs trapped in host tissues, it also increases the risk for the development of autoimmunity reflecte...

journal_title：Parasite immunology

authors： Wang X,Fu Q,Song R,Duan B,Bergquist R,Xu J,Li S,Zhou D,Qin Z

更新日期：2018-10-01 00:00:00

abstract：:Research undertaken over the past 40 years has established many of the general principals concerning immunity to taeniid cestodes. Although much is well understood about the host-protective mechanisms against taeniids and this knowledge has been exploited in studies on vaccine development, many aspects require further...

journal_title：Parasite immunology

authors： Lightowlers MW

更新日期：2010-11-01 00:00:00

abstract：:Lysates of the haematoprotozoa Trypanosoma brucei or Plasmodium berghei stimulated murine peritoneal exudate cells to release a mediator, which suppressed lipoprotein lipase activity in differentiating 3T3-L1 preadipocytes. The parasite-induced mediator suppressed the activity of cell surface lipoprotein lipase up to ...

journal_title：Parasite immunology

authors： Hotez PJ,Le Trang N,Fairlamb AH,Cerami A

更新日期：1984-05-01 00:00:00

abstract：:Longitudinal cohort studies are important to describe the dynamics of naturally acquired antibody response profiles to defined Plasmodium falciparum malaria antigens relative to clinical malaria episodes. In children under 7 years of age in The Gambia, serum IgG responses were measured to P. falciparum merozoite antig...

journal_title：Parasite immunology

authors： Akpogheneta OJ,Dunyo S,Pinder M,Conway DJ

更新日期：2010-04-01 00:00:00

abstract：:The present paper reviews the available literature on the development of immunity to animal Schistosoma infections. The majority of the studies on animal schistosomiasis were performed in cattle and pigs and only Schistosoma mattheei, S. bovis and S. japonicum received particular attention, mainly because of their rec...

journal_title：Parasite immunology

authors： Vercruysse J,Gabriel S

更新日期：2005-07-01 00:00:00

abstract：:Trichuris muris is an intestinal nematode that invades the colonic epithelium triggering a mucosal inflammation. Vitamin A and its active metabolite retinoic acid are strongly linked with the modulation of gut immune responses. Here, we describe the temporal changes in the expression of aldehyde dehydrogenase (ALDH) e...

journal_title：Parasite immunology

authors： Hurst RJ,Else KJ

更新日期：2013-07-01 00:00:00

abstract：:We assayed the vaccine potentialities of a recombinant S. bovis-derived glutathione S-transferase (rSb28GST), member of a molecular family already shown to have protective capacities in the S. mansoni and S. japonicum models. Injection of the rSb28GST in Freund's Complete Adjuvant resulted in good specific IgG respons...

journal_title：Parasite immunology

authors： Boulanger D,Trottein F,Mauny F,Bremond P,Couret D,Pierce RJ,Kadri S,Godin C,Sellin E,Lecocq JP

更新日期：1994-08-01 00:00:00

abstract：:Host cell death induced by Entamoeba histolytica is an important mechanism for both host defence and microbial immune evasion during human amoebiasis. However, the signalling pathways underlying cell death induced by E. histolytica are not fully understood. This study investigated the involvement of the protein tyrosi...

journal_title：Parasite immunology

authors： Kim KA,Lee YA,Shin MH

更新日期：2010-03-01 00:00:00

abstract：:Neurocysticercosis (NCC), one of the most common parasitic diseases of the central nervous system, is caused by Taenia solium. This parasite involves two hosts, intermediate hosts (pig and human) and a definitive host (human) and has various stages in its complex life cycle (eggs, oncosphere, cysticerci and adult tape...

journal_title：Parasite immunology

authors： Arora N,Tripathi S,Kumar P,Mondal P,Mishra A,Prasad A

更新日期：2017-07-01 00:00:00

abstract：:Human toxocariasis is a helminth zoonosis resulting from accidental infection of humans by the roundworms Toxocara canis (T. canis) and cati (T. cati). The infection occurs in five forms: systemic (VLM), ocular, neurological, covert and asymptomatic. The aim of this study was to characterize the radiological and immun...

journal_title：Parasite immunology

authors： Mazur-Melewska K,Jończyk K,Modlińska-Cwalińska A,Figlerowicz M,Służewski W

更新日期：2014-12-01 00:00:00

abstract：:An attenuated line of Leishmania mexicana (the L. mexicana H-line) has been established by culturing in vitro under gentamicin pressure. BALB/c mice infected with the L. mexicana H-line developed a CD4(+)Th1-like response, indicated by the cytokine profile of their splenocytes stimulated by L. mexicana wild-type (WT) ...

journal_title：Parasite immunology

authors： Daneshvar H,Hagan P,Phillips RS

更新日期：2003-11-01 00:00:00

abstract：:Entamoeba histolytica is the aetiological agent of invasive amoebiasis, the third leading parasitic cause of mortality in the world. The disease can be easily cured by chemotherapy; however, prevention, mainly in the form of vaccination, could greatly decrease the incidence of the disease, and possibly help in its era...

journal_title：Parasite immunology

authors： Gaucher D,Chadee K

更新日期：2003-02-01 00:00:00

abstract：:Isotype/subclass-specific antibody responses to adult Onchocerca volvulus extract (OvAg) were assessed by both ELISA and immunoblotting for a group of putatively immune individuals (PIs, n = 29) from a hyperendemic area in Ecuador and for a group of infected individuals (INFs, n = 470) from the same regions. As a grou...

journal_title：Parasite immunology

authors： Stewart GR,Elson L,Araujo E,Guderian R,Nutman TB,Bradley JE

更新日期：1995-07-01 00:00:00

abstract：:Dirofilaria immitis is the agent of the heartworm disease in canids and felids, and of pulmonary dirofilariosis in man. Like other filariae, D. immitis harbours endosymbion Wolbachia bacteriae. In this work we analyse the response of specific IgE antibodies against both D. immitis antigens and the Wolbachia surface pr...

journal_title：Parasite immunology

authors： Pou-Barreto C,Quispe-Ricalde MA,Morchón R,Vázquez C,Genchi M,Postigo I,Valladares B,Simón F

更新日期：2008-11-01 00:00:00

abstract：:SUMMARY Previous experiments have shown that genetic resistance to infection by Teladorsagia circumcincta in sheep can be measured by the level of IgA in gastric mucus, jointly with other parameters. The aim of this study has been to observe the influence of IgA on adult worms. The experiment was carried out with Chur...

journal_title：Parasite immunology

authors： Martínez-Valladares M,Vara-Del Río MP,Cruz-Rojo MA,Rojo-Vázquez FA

更新日期：2005-06-01 00:00:00

abstract：:A limiting dilution microculture system was optimized to quantify the frequency of Theileria parva-specific cytotoxic T lymphocyte precursors (CTLp) in peripheral blood mononuclear cells (PBMC) from immune cattle. Optimal results were obtained with responder cell input levels ranging from 2 x 10(4)/well to 6.25 x 10(2...

journal_title：Parasite immunology

authors： Taracha EL,Goddeeris BM,Scott JR,Morrison WI

更新日期：1992-03-01 00:00:00

abstract：:Infective forms of Trypanosoma cruzi, the parasite that causes Chagas' disease, express on their surface an enzyme denominated trans-sialidase (TS). The present study was designed to evaluate the naturally acquired immune responses to a bacterial recombinant protein representing the catalytic domain of TS in chronical...

journal_title：Parasite immunology

authors： Ribeirão M,Pereira-Chioccola VL,Rénia L,Augusto Fragata Filho A,Schenkman S,Rodrigues MM

更新日期：2000-01-01 00:00:00

abstract：:Groups of five dogs were vaccinated against Babesia canis using soluble parasite (SPA) antigens from in vitro cultures. Although vaccination did not significantly alter peripheral parasitaemia upon challenge, protected animals had lower levels of SPA in the plasma after a challenge infection. The severity of anaemia c...

journal_title：Parasite immunology

authors： Schetters TP,Scholtes NC,Kleuskens JA,Bos HJ

更新日期：1996-01-01 00:00:00

abstract：:On a B10 (Lshs) genetic background, the development of acquired T cell mediated immunity to Leishmania donovani infection in mice is under H-2 linked genetic control. Following intravenous inoculation of 10(7) amastigotes three phenotypic patterns of recovery have been described: 'early cure' (H-2r,s), 'cure' (H-2b) a...

journal_title：Parasite immunology

authors： Ulczak OM,Blackwell JM

更新日期：1983-09-01 00:00:00

abstract：:The in vitro binding serum complement (C) components to Schistosoma mansoni worms was studied. By exposing frozen sections of adult male and female parasites to normal human serum, binding of both classical and alternative pathway C components was observed. By immunofluorescence (IFL) microscopy selective binding of C...

journal_title：Parasite immunology

authors： Linder E,Huldt G

更新日期：1983-03-01 00:00:00

abstract：:Analysis by one-dimensional (1-D) SDS-PAGE/Western blotting of whole mite extract (larval and adult stages) with sheep sera taken 0-84 days after infection with the sheep scab mite, Psoroptes ovis revealed a progressive IgE antibody response, with a dominant high molecular weight allergen (MW 180 kDa) detected early d...

journal_title：Parasite immunology

authors： Huntley JF,Machell J,Nisbet AJ,Van den Broek A,Chua KY,Cheong N,Hales BJ,Thomas WR

更新日期：2004-08-01 00:00:00

abstract：:Plasmodium falciparum-specific antibodies tend to be short-lived, but their cognate memory B cells (MBCs) circulate in the peripheral blood of exposed subjects for several months or years after the last infection. However, the time course of antigen-specific antibodies and B-cell responses to the relatively neglected ...

journal_title：Parasite immunology

authors： Soares RR,Cunha CF,Ferraz-Nogueira R,Marins-Dos-Santos A,Rodrigues-da-Silva RN,da Silva Soares I,da Costa Lima-Junior J,Bertho AL,Ferreira MU,Scopel KKG

更新日期：2019-09-01 00:00:00

abstract：:Two monoclonal antibodies against the surface of S. mansoni schistosomula were found to confer significant passive protection to mice (M7B3A, range 28-70%; M22H12C, range 14-58%). No additive effect was observed when both were transferred together. Neither McAb bound to the cercarial surface but both bound to the surf...

journal_title：Parasite immunology

authors： Bickle QD,Andrews BJ,Taylor MG

更新日期：1986-01-01 00:00:00

abstract：:In modern societies, diseases that are driven by dysregulated immune responses are increasing at an alarming pace, such as inflammatory bowel diseases and diabetes. There is an urgent need to understand these epidemiological trends, which are likely to be driven by the changing environment of the last few decades. The...

journal_title：Parasite immunology

authors： Loke P,Lim YA

更新日期：2015-06-01 00:00:00

abstract：:A surface enriched fraction was prepared from adults of Onchocerca volvulus by brief extraction of entire worms with detergent. This was then gel filtered to yield a low molecular weight fraction which functioned specifically in ELISA analysis. An identical result was also obtained when the related cattle parasite, O....

journal_title：Parasite immunology

authors： Cabrera Z,Parkhouse RM

更新日期：1987-01-01 00:00:00

abstract：:Leishmaniasis is a parasitic disease transmitted by the bite of Leishmania-infected sand flies. Here we show for the first time the ability of Maxadilan (Max), a vasodilatory peptide isolated from the sand fly Lutzomyia longipalpis, and salivary gland lysate (SGL) from Phlebotomus papatasi to decrease the secretion of...

journal_title：Parasite immunology

authors： Rogers KA,Titus RG

更新日期：2003-03-01 00:00:00

abstract：:Haemonchus contortus is an economically important parasite that survives the host defense system by modulating the immune response. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is secreted by the parasite and the host responds by producing anti-enzyme antibodies. The enzyme inhibits complement cascade, an arm of t...

journal_title：Parasite immunology

authors： Rajan P,Mishra PKK,Joshi P

更新日期：2019-02-01 00:00:00

abstract：:Plasma from chronic or advanced hepatosplenic schistosomiasis (mansoni) patients (PCS) suppressed mitogen-induced responses of normal human peripheral blood mononuclear cells. 1 x 10(5) Ficoll-Hypaque isolated lymphocytes were cultured in 100 microliter RPMI 1640 media with 100 microliter plasma preparation and stimul...

journal_title：Parasite immunology

authors： Kamal KA,Higashi GI

更新日期：1982-07-01 00:00:00