Abstract：
:Thirteen healthy women (age 24-44 yrs) were studied during their menstrual cycle. Samples were taken 2-3 times weekly for six consecutive weeks. Plasma concentrations of oestradiol and progesterone were determined in each blood sample and only women found to be ovulatory were included. From the hormone data the cycles were divided in five phases (early follicular phase, late follicular phase, early luteal phase, late luteal phase and menstrual period). The samples for the coagulation and fibrinolysis assays as well as the venous occlusion (20 min) tests were drawn or performed between 8-9 a m after fasting for 8 hrs. The fibrinogen F VIII:C and AT III were assayed and did not show any variations through the study period. Neither were any differences found in platelet counts, platelet mean volumes or platelet function measured as platelet adhesion and plasma beta-thromboglobulin. The fibrinolytic activity after venous occlusion decreased slightly during the late luteal phase (phase 4) as compared with the other phases. Large individual differences were, however, seen and no statistically significant differences between the five different phases were found. The plasminogen activator inhibitor (PAI-1) varied during the cycle but in most individuals within the normal range. In 7/13 women substantial fluctuations of the fibrinolytic activities during the cycle were seen. Four women had a significant fall of the fibrinolytic activity after venous occlusion during the late luteal phase (phase 4) and 3 others during the menstrual phase (phase 5). No co-variation between the fibrinolytic activities and PAI-1 was found. Multiple regression analysis showed a co-variation between fibrinolytic activities and progesterone.
journal_name
Ups J Med Scijournal_title
Upsala journal of medical sciencesauthors
Siegbahn A,Odlind V,Hedner U,Venge Pdoi
10.3109/03009738909178559subject
Has Abstractpub_date
1989-01-01 00:00:00pages
137-52issue
2eissn
0300-9734issn
2000-1967journal_volume
94pub_type
杂志文章abstract：:Vasospastic reactions to cold have been suggested to be related to altered blood rheology, as has been reported in both primary (PVD) and traumatic (TVD) vasospastic disease. Measurements of whole blood viscosity, plasma viscosity, erythrocyte deformability and finger systolic pressure (FSP) were performed in 18 patie...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738509178639
更新日期：1985-01-01 00:00:00
abstract：:Epidemiological data on drug-treated diabetes mellitus was obtained by analyzing prescriptions of insulin and oral antidiabetics in the county of Jämtland Sweden. During a 12-year period, from 1971 to 1982, the prevalence of diabetes increased from 1.5% to 2.2%, while there was no significant change in the annual inci...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738609178494
更新日期：1986-01-01 00:00:00
abstract：:Twelve patients suffering from sickle cell anaemia (Hb less than 75 g/l) with SS-haemoglobin were studied with special regard to Band 3-protein content in their erythrocyte membranes on SDS-PAGE. They were compared in this respect with 7 asymptomatic individuals with AS-haemoglobin and 10 healthy controls with the ord...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009739109179256
更新日期：1991-01-01 00:00:00
abstract：:Allergic alveolitis due to mold dust inhalation in farmers is a severe but rare disease in Scandinavia. In this report 38 cases of the disease are presented. There were 31 men and 7 women, with mean ages of 46 and 38 years respectively. Strict diagnostic criteria were used, resulting in 21 definite, 12 probable and 5 ...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738909178568
更新日期：1989-01-01 00:00:00
abstract：:Introduction: Carotid endarterectomy (CEA) is a surgical procedure used in the prevention of ischemic stroke. However, this procedure can cause complications of ischemia-reperfusion injury to the brain. Clusterin (CLU) is a cytoprotective chaperone protein that is released from neurons in response to various neurologi...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.1080/03009734.2019.1646359
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Autologous chondrocyte implantation (ACI) is considered a promising choice for the treatment of cartilage defects. However, the application of ACI to osteoarthritic patients is, in general, contraindicated. The purpose of this study is to evaluate the efficiency of three-dimensionally structured ACI (3D-ACI;...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009734.2011.552812
更新日期：2011-05-01 00:00:00
abstract：:Radical surgery for renal cancer with invasion of the inferior vena cava can improve the patient's quality of life and, in some cases, offer longer survival or even cure. With a carefully planned surgical approach it is possible to remove renal tumours with thrombotic extension to the most proximal part of the inferio...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738509178646
更新日期：1985-01-01 00:00:00
abstract：:Diabetes in the mother may cause disturbances in the chondrocyte development in the embryo. A rat model was used to investigate whether this was reflected in the production of proteoglycans by cells from two embryonic regions. One of these regions is resistant (limb bud) and the other susceptible (mandibular arch) to ...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009739009178574
更新日期：1990-01-01 00:00:00
abstract：:A thymolipoma in an 8-year-old boy is reported. The tumour had appeared on a routine chest X-ray as a broadened heart shadow and a peculiar right heart contour. Cardiac hypertrophy was suspected primarily. At thoracotomy a thymic tumour was found. ...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009737609179036
更新日期：1976-01-01 00:00:00
abstract：:This study was done to evaluate the absorption of a single oral dose of 12 mg oestriol (Triovex, Leo AB, Sweden) and to confirm the hypothesis that the enterohepatic recirculation can prolong the plasma oestriol elevation obtained. Twelve menopausal women, six of whom had been cholecystectomized earlier, were given 12...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738409178470
更新日期：1984-01-01 00:00:00
abstract：:Cytosolic carbonic anhydrases CAI, CAII, and CAIII from liver, and CAII, and CAIII from muscle of adult male Sprague-Dawley rats were purified to homogeneity. CAIII from liver and muscle had the same amino acid composition and were immunochemically similar. Their kinetic properties at 0 degrees C were also similar. Km...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/2000-1967-131
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Two standard sets of criteria are used to evaluate the tumor response of hepatocellular carcinoma (HCC): RECIST (Response Evaluation Criteria in Solid Tumors) and modified RECIST (mRECIST). The purpose was to compare two tumor response evaluation criteria, RECIST version 1.1 and mRECIST, for HCC treated usin...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章,多中心研究
doi：10.3109/03009734.2012.729104
更新日期：2013-03-01 00:00:00
abstract：:Factors that may influence the water transport through the skin in infants on their first day of life were studied with a method based on determination of the vapour pressure gradient in the air layer close to the skin surface. The evaporation rate from the skin was found to vary with the site of measurement, ambient ...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738109179207
更新日期：1981-01-01 00:00:00
abstract：:A method for estimation of the erythrocyte sedimentation from repeated measurements during the initial part of the sedimentation phase is described. Based on the measurements between 18 and 24 minutes after the beginning of the reaction, the sedimentation at 60 minutes is estimated. The estimate is highly correlated t...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009739409179362
更新日期：1994-01-01 00:00:00
abstract：:Since 1975 Sweden has had a patient insurance system to compensate patients for health-related injuries. The system was initially based on a voluntary patient insurance solution, but in 1997 it was replaced by the Patient Insurance Act. The current Act covers both physical and mental injuries. Although about 9,000-10,...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009730903350749
更新日期：2010-05-01 00:00:00
abstract：:One hundred and fifty women with a diagnosis of toxaemia of pregnancy treated in the Department of Obstetrics and Gynaecology, University Hospital, Uppsala between 1964 and 1968 were investigated. One hundred women were still living in the area in 1975 and thus could be restudied. The participation rate was 100% in th...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009737809179119
更新日期：1978-01-01 00:00:00
abstract：:Post-heparin plasma hepatic triglyceride lipase (H-TGL) and lipoprotein lipase (LPL) activities were 8-34 and 3.5-21 (range) mu mol/ml/hr respectively in males with normal serum lipid concentrations. In females the corresponding values were 4-25 and 4-16 mu mol/ml/hr. No significant differences were observed between a...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009737909179158
更新日期：1979-01-01 00:00:00
abstract：:Background: Hepatic de novo lipogenesis (DNL) is ideally measured in very low-density lipoprotein (VLDL)-triacylglycerol (TAG). In the fasting state, the majority of plasma TAG typically represents VLDL-TAG; however, the merits of measuring DNL in total plasma TAG have not been assessed. This study aimed to assess the...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.1080/03009734.2020.1739789
更新日期：2020-08-01 00:00:00
abstract：:In early ARDS (Adult Respiratory Distress Syndrome) and other inflammatory pulmonary disorders the lung might benefit from a high local deposition of an active drug, in order to optimize the local concentration without systemic side effects. In this methodological study we used pigs under controlled ventilation. The s...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009739009178581
更新日期：1990-01-01 00:00:00
abstract：:Familial aggregation of patients with ovarian carcinoma is unusual. A family with four affected members in three consecutive generations is described. The tumors were all of the serous papillary adenocarcinoma type. The pattern of appearance of the malignant disorder in the present family may be explained as the resul...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009737609179047
更新日期：1976-01-01 00:00:00
abstract：:A material comprising all children in Sweden with acute lymphoblastic leukemia diagnosed in the years 1973-80 was analysed statistically. The total number of children was 505. Studies were made of 38 different variables, using frequency tables, cross tables, life table studies (1) and linear regression analysis accord...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738209178424
更新日期：1982-01-01 00:00:00
abstract：:This study was undertaken to evaluate the utility of a modified technique of triplex scanning of the lower extremity arteries in 20 subjects without any clinical signs of arterial disease. The distal aorta and iliac arteries were examined with the subject in supine position and lying slightly on the opposite side. By ...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009739609178917
更新日期：1996-01-01 00:00:00
abstract：:Twenty-one cases of hepatic abscesses treated during a period of four years (from 1981 to 1985) at the University of Patras, Greece, are presented. This material includes 10 cases with abscesses caused by suppurated echinococcal cysts, corresponding to 21% of the total number of 47 cases of echinococcal cysts of the l...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738809178554
更新日期：1988-01-01 00:00:00
abstract：:Acid phosphatase in serum was measured in 116 patients with prostatic disease, benign in 59 and malignant in 57 cases. Comparisons were made between radioimmunoassay (RIA) and an enzymatic method. The correlation coefficient between the respective values was 0.96 in patients with untreated prostatic cancer, indicating...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738309178446
更新日期：1983-01-01 00:00:00
abstract：:An investigation was made of 150 women who were diagnosed at the Department of Obstetrics and Gynaecology, University Hospital, Uppsala in 1964-68 as having toxaemia of pregnancy. Eleven had eclampsia and the remainder pre-eclampsia. Toxaemia occurred in 0.88% (average) of all parturients during the study period. Some...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009737809179108
更新日期：1978-01-01 00:00:00
abstract：:Inverse ratio ventilation (IRV) is commonly used in clinical practice. Several studies have used IRV in order to recruit collapsed alveoli. In a randomised trial in twelve surfactant depleted piglets, the lungs were ventilated with sufficient positive end-expiratory pressure (PEEP) to prevent end-expiratory collapse, ...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009739609178925
更新日期：1996-01-01 00:00:00
abstract：:A new stimulatory luteinizing hormone-releasing hormone (LRH) analogue D-Ser(TBU)(6)-EA(10)-LRH was administered subcutaneously in a dose of 10 microg into 10 women with amenorrhoea. The injection resulted in a 20-fold increase of the LH level in blood and a 5-fold increase of the FSH level with maxima at 4 and 6 h af...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009737709179054
更新日期：1977-01-01 00:00:00
abstract：:Different methodological aspects on the assay of human erythrocyte catechol-O-methyltransferase (COMT) activity were studied. No temporal variations were found either over a 24 hour period or over one month. Erythrocytes from whole blood collected with any of the anticoagulants heparin, EDTA or citrate could be used a...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009738109179242
更新日期：1981-01-01 00:00:00
abstract：:Alkaline phosphatase from calf intestinal mucosa dephosphorylated histone H1 and fibrinogen that had been phosphorylated with protein kinase C. The reaction velocity was dependent on the ionic strength of the buffer; decreasing with increasing concentration. The pH optimum was around 7, which is lower than pH-optima d...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/03009739109179262
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:There is evidence suggesting that genetic variants in the chondroitin sulfate proteoglycan2 (CSPG2, also known as versican) gene are involved in the pathogenesis of intracranial aneurysms (IAs). Some authors have demonstrated that single nucleotide polymorphisms (SNPs) rs173686 and rs251124 in the promoter r...
journal_title：Upsala journal of medical sciences
pub_type： 杂志文章
doi：10.3109/2000-1967-201
更新日期：2007-01-01 00:00:00
