当前位置： SCI文献检索 > ANNALS OF SURGICAL ONCOLOGY期刊下所有文献 > Clinical and socioeconomic factors influence treatment decisions in Graves' disease.

Clinical and socioeconomic factors influence treatment decisions in Graves' disease.

Abstract：

BACKGROUND:Definitive treatment of Graves' disease includes radioactive iodine (RAI) and thyroidectomy, but utilization varies. We hypothesize that, in addition to clinical reasons, there are socioeconomic factors that influence whether a patient undergoes thyroidectomy or RAI. METHODS:Patients treated for Graves' disease between August 2007 and September 2013 at our university hospital were included. A comparative analysis of clinical and socioeconomic factors was completed. RESULTS:Of 427 patients, 300 (70 %) underwent RAI, whereas 127 (30 %) underwent surgery. Multiple factors were associated with surgery: younger age (mean 36 vs. 41 years, p < 0.01), female gender (33 vs. 19 % males, p = 0.01), black race (56 vs. 28 % nonblack, p < 0.01), Medicaid or uninsured (43 vs. 27 % private insurance or Medicare, p < 0.01), ophthalmopathy (38 vs. 26 %, p < 0.01), goiter (35 vs. 23 %, p < 0.01), and lowest quartile of median household income (38 vs. 27 % upper three quartiles, p = 0.03). Thyroidectomy increased annually, with 52 % undergoing surgery during the final year (p < 0.01). Adjusting for confounding, younger age (odds ratio [OR] 1.04; 95 % confidence interval [CI] 1.02, 1.05), female gender (OR 2.06; 95 % CI 1.06, 4.01), ophthalmopathy (OR 2.35; 95 % CI 1.40, 3.96), and later year of treatment (OR 1.66; 95 % CI 1.41, 1.95) remained significantly associated with surgery. CONCLUSIONS:Surgery has now become the primary treatment modality of choice for Graves' disease at our institution. Clinical factors are the main drivers behind treatment choice, but patients with lower SES are more likely to have clinical features best treated with surgery, underlying the importance of improving access to quality surgical care for all patients.

journal_name

Ann Surg Oncol

journal_title

Annals of surgical oncology

authors

Elfenbein DM,Schneider DF,Havlena J,Chen H,Sippel RS

doi

10.1245/s10434-014-4095-6

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

1196-9

issue

4

eissn

1068-9265

issn

1534-4681

journal_volume

22

pub_type

杂志文章

相关文献

ANNALS OF SURGICAL ONCOLOGY文献大全
  • Prognostic value of basal phenotype in HER2-overexpressing breast cancer.

    abstract：BACKGROUND:Primary breast cancers that overexpress human epidermal growth factor receptor 2 have variable biological features and clinical outcomes. A subgroup of HER2-overexpressing tumors that express basal-like immunohistochemical markers-the so-called basal-HER2+ subtype--is associated with poor prognosis. We inves...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-011-2032-5

    authors： Bagaria SP,Ray PS,Wang J,Kropcho L,Chung A,Sim MS,Shamonki JM,Martino S,Cui X,Giuliano AE

    更新日期：2012-03-01 00:00:00

  • Comparison of Detrusor Muscle Sampling Rate in Monopolar and Bipolar Transurethral Resection of Bladder Tumor: A Randomized Trial.

    abstract：PURPOSE:Our aim was to investigate the detrusor muscle sampling rate after monopolar versus bipolar transurethral resection of bladder tumor (TURBT). METHODS:This was a single-center, prospective, randomized, phase III trial on monopolar versus bipolar TURBT. Baseline patient characteristics, disease characteristics a...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,随机对照试验

    doi：10.1245/s10434-016-5700-7

    authors： Teoh JY,Chan ES,Yip SY,Tam HM,Chiu PK,Yee CH,Wong HM,Chan CK,Hou SS,Ng CF

    更新日期：2017-05-01 00:00:00

  • Hilar cholangiocarcinoma: a review and commentary.

    abstract：:Hilar cholangiocarcinoma is an uncommon cause of malignant biliary obstruction marked by local tumor spread for which surgery offers the only chance of cure. The diagnostic evaluation and surgical management of this disease continues to evolve. Although direct cholangiography and endoscopic biliary procedures have bee...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,评审

    doi：10.1007/s10434-000-0055-4

    authors： Chamberlain RS,Blumgart LH

    更新日期：2000-01-01 00:00:00

  • A randomized prospective study of lumpectomy margin assessment with use of MarginProbe in patients with nonpalpable breast malignancies.

    abstract：BACKGROUND:The presence of tumor cells at the margins of breast lumpectomy specimens is associated with an increased risk of ipsilateral tumor recurrence. Twenty to 30 % of patients undergoing breast-conserving surgery require second procedures to achieve negative margins. This study evaluated the adjunctive use of the...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,随机对照试验

    doi：10.1245/s10434-014-3602-0

    authors： Schnabel F,Boolbol SK,Gittleman M,Karni T,Tafra L,Feldman S,Police A,Friedman NB,Karlan S,Holmes D,Willey SC,Carmon M,Fernandez K,Akbari S,Harness J,Guerra L,Frazier T,Lane K,Simmons RM,Estabrook A,Allweis T

    更新日期：2014-05-01 00:00:00

  • Accelerated hepatic arginine transport in the tumor-bearing rat.

    abstract：BACKGROUND:Arginine plays a pivotal role in regulating ureagenesis, polyamine biosynthesis, and nitric oxide production, metabolic pathways that may be stimulated in the liver of the tumor-bearing host. Normally, plasma arginine is excluded from the hepatocyte intracellular space by the low basal activity of its membra...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1007/BF02303559

    authors： Espat NJ,Copeland EM,Souba WW

    更新日期：1994-03-01 00:00:00

  • Endoscopic and pathologic findings associated with clinical outcomes of melanoma in the upper gastrointestinal tract.

    abstract：BACKGROUND:Melanoma that involves the upper gastrointestinal (GI) tract is rare and studies relating to endoscopic and pathologic findings with clinical outcomes are lacking. We reviewed the gross and microscopic patterns of the upper GI tract in primary and metastatic melanoma, and examined their association with clin...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-014-3637-2

    authors： Ahn JY,Hwang HS,Park YS,Kim HR,Jung HY,Kim JH,Lee SE,Kim MA

    更新日期：2014-08-01 00:00:00

  • Impact of multifocal or multicentric disease on surgery and locoregional, distant and overall survival of 6,134 breast cancer patients treated with neoadjuvant chemotherapy.

    abstract：BACKGROUND:The impact of tumor focality on type of surgery, local recurrence rate, and survival after neoadjuvant chemotherapy (NACT) for breast cancer is not fully understood. This study aimed to compare local recurrence-free survival (LRFS), disease-free survival (DFS), and overall survival (OS) according to focality...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1245/s10434-014-4122-7

    authors： Ataseven B,Lederer B,Blohmer JU,Denkert C,Gerber B,Heil J,Kühn T,Kümmel S,Rezai M,Loibl S,von Minckwitz G

    更新日期：2015-04-01 00:00:00

  • Initial results with preoperative tattooing of biopsied axillary lymph nodes and correlation to sentinel lymph nodes in breast cancer patients.

    abstract：BACKGROUND:Pretreatment evaluation of axillary lymph nodes (ALNs) and marking of biopsied nodes in patients with newly diagnosed breast cancer is becoming routine practice. We sought to test tattooing of biopsied ALNs with a sterile black carbon suspension (Spot™). The intraoperative success of identifying tattooed ALN...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-014-4034-6

    authors： Choy N,Lipson J,Porter C,Ozawa M,Kieryn A,Pal S,Kao J,Trinh L,Wheeler A,Ikeda D,Jensen K,Allison K,Wapnir I

    更新日期：2015-02-01 00:00:00

  • Comparison of multiphase CT, FDG-PET and intra-operative ultrasound in patients with colorectal liver metastases selected for surgery.

    abstract：BACKGROUND:For patients with colorectal liver metastases, resection is the treatment of choice. Careful selection of these patients is crucial in order to reduce the chance of unexpected findings at laparotomy and abandoning further surgical intervention. Here, we evaluate the predictive value of CT and FDG-PET of the ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-006-9259-6

    authors： Wiering B,Ruers TJ,Krabbe PF,Dekker HM,Oyen WJ

    更新日期：2007-02-01 00:00:00

  • Perceptions of contralateral breast cancer: an overestimation of risk.

    abstract：INTRODUCTION:The rate of contralateral prophylactic mastectomy (CPM) has recently increased. The aim of this study is to assess perceptions of contralateral breast cancer (CBC) risk among breast cancer patients and to evaluate tumor and patient factors associated with risk perception. METHODS:We conducted a prospectiv...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-011-1914-x

    authors： Abbott A,Rueth N,Pappas-Varco S,Kuntz K,Kerr E,Tuttle T

    更新日期：2011-10-01 00:00:00

  • The Landmark Series: Randomized Trials Examining Surgical Margins for Cutaneous Melanoma.

    abstract：:Between 1980 and 2004, six randomized, controlled trials (RCTs) have been performed to evaluate the width of surgical margin excision for primary cutaneous melanoma and its influence on recurrence and survival. These trials have led to the current recommendation of not more than a 2-cm margin excision and have allowed...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,评审

    doi：10.1245/s10434-019-07866-y

    authors： Angeles CV,Wong SL,Karakousis G

    更新日期：2020-01-01 00:00:00

  • Fluctuating mastectomy rates across time and geography.

    abstract：:In 2009, 2 single-institution studies from the United States reported increasing mastectomy rates during the last decade. We have recently reported unilateral mastectomy trends from a European database and demonstrated a significant trend of decreasing mastectomy rates from 38.1 % in 2005 to 13.1 % in 2010. A recent s...

    journal_title：Annals of surgical oncology

    pub_type： 社论

    doi：10.1245/s10434-013-2982-x

    authors： Garcia-Etienne CA,Tomatis M,Heil J,Danaei M,Rageth CJ,Marotti L,Rosselli Del Turco M,Ponti A

    更新日期：2013-07-01 00:00:00

  • Long-term outcome of patients with complete pathologic response after neoadjuvant chemoradiation for cT3 rectal cancer: implications for local excision surgical strategies.

    abstract：BACKGROUND:Neoadjuvant chemoradiotherapy (CRT) followed by radical surgery including total mesorectal excision (TME) is standard treatment in patients with locally advanced rectal cancer. Emerging data indicate that patients with complete pathologic response (ypCR) after CRT have favorable outcome, suggesting the possi...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-011-1822-0

    authors： Belluco C,De Paoli A,Canzonieri V,Sigon R,Fornasarig M,Buonadonna A,Boz G,Innocente R,Perin T,Cossaro M,Polesel J,De Marchi F

    更新日期：2011-12-01 00:00:00

  • Combined hepatectomy and radiofrequency ablation for multifocal hepatocellular carcinomas: long-term follow-up results and prognostic factors.

    abstract：BACKGROUND:For multifocal hepatocellular carcinomas (HCCs) that are untreatable with resection only, locoregional therapies added to hepatectomy have been introduced. However, some preliminary reports have documented average survival results and relatively high complication rates. We evaluated the long-term survival re...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-007-9492-7

    authors： Choi D,Lim HK,Joh JW,Kim SJ,Kim MJ,Rhim H,Kim YS,Yoo BC,Paik SW,Park CK

    更新日期：2007-12-01 00:00:00

  • Tumor-associated macrophages promote oral cancer progression through activation of the Axl signaling pathway.

    abstract：BACKGROUND:Recent studies suggest that tumor-associated macrophages (TAMs) promote tumor growth and metastasis. Our previous report demonstrated that Axl signaling promotes carcinogenesis and progression of oral squamous cell carcinoma (OSCC). This study aims to test the potential involvement of growth arrest-specific ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-013-3400-0

    authors： Lee CH,Liu SY,Chou KC,Yeh CT,Shiah SG,Huang RY,Cheng JC,Yen CY,Shieh YS

    更新日期：2014-03-01 00:00:00

  • RAS Mutation is Associated with Unsalvageable Recurrence Following Hepatectomy for Colorectal Cancer Liver Metastases.

    abstract：BACKGROUND:RAS mutation status predicts survival after hepatectomy for colorectal liver metastases (CRLM) and survival after repeat hepatectomy for intrahepatic recurrence. This study was aimed at determining the impact of RAS mutation on amenability of recurrence to local therapy and on post-recurrence survival follow...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-018-6517-3

    authors： Okuno M,Goumard C,Kopetz S,Vega EA,Joechle K,Mizuno T,Omichi K,Tzeng CD,Chun YS,Vauthey JN,Conrad C

    更新日期：2018-08-01 00:00:00

  • Harvest of at Least 23 Lymph Nodes is Indispensable for Stage N3 Gastric Cancer Patients.

    abstract：BACKGROUND:The National Comprehensive Cancer Network (NCCN) recommends that at least 15 lymph nodes (LNs) be removed during radical gastrectomy. This study aims to investigate the optimal number of LNs resected for radical gastrectomy. PATIENTS AND METHODS:From September 2008 to March 2015, a total of 1990 gastric can...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-016-5667-4

    authors： Zheng G,Feng F,Guo M,Xu G,Liu S,Liu Z,Sun L,Hong L,Yang J,Lian X,Fan D,Zhang H

    更新日期：2017-04-01 00:00:00

  • Routine screening for local recurrence following breast-conserving therapy for cancer with dynamic contrast-enhanced magnetic resonance imaging of the breast.

    abstract：BACKGROUND:Dynamic contrast-enhanced magnetic resonance imaging (MRI) of the breast is highly sensitive for the diagnosis of primary breast malignancy. We investigated the clinical application of dedicated dynamic breast MR for routine screening for local recurrence following breast-conserving therapy. METHODS:Patient...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1007/BF02303784

    authors： Drew PJ,Kerin MJ,Turnbull LW,Imrie M,Carleton PJ,Fox JN,Monson JR

    更新日期：1998-04-01 00:00:00

  • Correction to: Clinical Surveillance After Macroscopically Complete Surgery for Low-Grade Appendiceal Mucinous Neoplasms (LAMN) with or Without Limited Peritoneal Spread: Long-Term Results in a Prospective Series.

    abstract：:In the original article Massimo Milione's last name was spelled incorrectly. It is correct as reflected here. The original article has also been updated. ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,已发布勘误

    doi：10.1245/s10434-018-6341-9

    authors： Guaglio M,Sinukumar S,Kusamura S,Milione M,Pietrantonio F,Battaglia L,Guadagni S,Baratti D,Deraco M

    更新日期：2018-12-01 00:00:00

  • Total Laparoscopic Resection of Hilar Cholangiocarcinoma Type 3b: Applying a Parachute Technique for Hepaticojejunostomy.

    abstract：BACKGROUND:Laparoscopic liver resection for perihilar cholangiocarcinoma (pCCA) is still in its infancy. The biliary-enteric reconstruction represents one of the most delicate parts of this minimally invasive procedure. METHODS:In this study, a 78-year old woman with perihilar cholangiocarcinoma (pCCA) type 3b underwe...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-09175-1

    authors： Sucher R,Scheuermann U,Seehofer D

    更新日期：2020-09-30 00:00:00

  • Lymph node dissection after chemoradiation in esophageal cancer: a subgroup analysis of patients with and without pathological response.

    abstract：BACKGROUND:Extensive lymph node dissection (LND) is beneficial in primarily resected esophageal cancer patients. Such benefit was believed to be seen in neoadjuvant chemoradiotherapy (CRT)-treated patients, but evidence was inconsistent. We hypothesized that CRT might offset the benefit of LND in certain subgroup of pa...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-012-2402-7

    authors： Chao YK,Liu HP,Hsieh MJ,Wu YC,Liu YH,Yeh CH,Chang HK,Tseng CK

    更新日期：2012-10-01 00:00:00

  • Prognostic significance of c-erbB-2 and vascular endothelial growth factor in colorectal liver metastases.

    abstract：BACKGROUND:The prognostic value of c-erbB-2 and vascular endothelial growth factor (VEGF) expression in colorectal liver metastases (CLM) is unclear. The purpose of this study was to clarify the relationship of c-erbB-2 and VEGF with the clinicopathological parameters and the survival results in CLM. METHODS:For 44 pa...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-009-0897-3

    authors： Chen J,Li Q,Wang C,Wu J,Zhao G

    更新日期：2010-06-01 00:00:00

  • Effects of Antihypertensive Drugs on Outcomes of Breast Reconstruction.

    abstract：BACKGROUND:Angiotensin receptor blocker (ARB), a commonly used antihypertensive drug, is reported to affect wound healing and flap survival in animal models. However, this has not been elucidated in a clinical series. This study aimed to investigate the impact that perioperative use of ARB has on outcomes after breast ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-019-07293-z

    authors： Park JW,Lee KT,Jeon BJ,Pyon JK,Bang SI,Mun GH

    更新日期：2019-06-01 00:00:00

  • Clinical and pathologic factors associated with distant metastasis and survival in patients with thin primary cutaneous melanoma.

    abstract：BACKGROUND:Approximately 3-5% of patients with thin (≤ 1 mm) cutaneous melanomas develop distant metastases. We sought to identify clinical and pathologic factors associated with distant metastasis and survival in a large number of patients with thin melanoma treated at a single institution. METHODS:We identified pati...

    journal_title：Annals of surgical oncology

    pub_type： 临床试验,杂志文章

    doi：10.1245/s10434-012-2265-y

    authors： Murali R,Haydu LE,Long GV,Quinn MJ,Saw RP,Shannon K,Spillane AJ,Stretch JR,Kefford RF,Thompson JF,Scolyer RA

    更新日期：2012-06-01 00:00:00

  • Re-excision rates of invasive ductal carcinoma with lobular features compared with invasive ductal carcinomas and invasive lobular carcinomas of the breast.

    abstract：BACKGROUND:Invasive ductal carcinoma (IDC) with lobular features (IDC-L) is not recognized as a subtype of breast cancer. We previously showed that IDC-L may be a variant of IDC with clinicopathological characteristics more similar to invasive lobular carcinoma (ILC). We sought to determine the re-excision rates of IDC...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-014-3871-7

    authors： Arps DP,Jorns JM,Zhao L,Bensenhaver J,Kleer CG,Pang JC

    更新日期：2014-12-01 00:00:00

  • The impact of the introduction of total mesorectal excision on local recurrence rate and survival in rectal cancer: long-term results.

    abstract：PURPOSE:To investigate the influence of the introduction of total mesorectal excision (TME) on local recurrence rate and survival in patients with rectal cancer. METHODS:A total of 171 consecutive patients underwent anterior or abdominoperineal resection for primary rectal cancer. When the TME technique was introduced...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-011-1571-0

    authors： Maurer CA,Renzulli P,Kull C,Käser SA,Mazzucchelli L,Ulrich A,Büchler MW

    更新日期：2011-07-01 00:00:00

  • Sentinel-Lymph-Node-Based Management or Routine Axillary Clearance? Five-Year Outcomes of the RACS Sentinel Node Biopsy Versus Axillary Clearance (SNAC) 1 Trial: Assessment and Incidence of True Lymphedema.

    abstract：PURPOSE:To determine whether the benefits of sentinel-node-based management (SNBM) over routine axillary clearance (RAC) persisted to 5 years. METHODS:A total of 1088 women with breast cancer less than 3 cm in diameter and clinically negative axillary nodes were randomized to SNBM with axillary clearance if the sentin...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,随机对照试验

    doi：10.1245/s10434-016-5669-2

    authors： Wetzig N,Gill PG,Espinoza D,Mister R,Stockler MR,Gebski VJ,Ung OA,Campbell I,Simes J

    更新日期：2017-04-01 00:00:00

  • Prognostic Utility of Pre- and Postoperative Circulating Tumor DNA Liquid Biopsies in Patients with Peritoneal Metastases.

    abstract：BACKGROUND:Circulating tumor DNA (ctDNA) is a promising technology for treatment selection, prognostication, and surveillance after definitive therapy. Its use in the perioperative setting for patients with metastatic disease has not been well studied. We characterize perioperative plasma ctDNA and its association with...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-08331-x

    authors： Baumgartner JM,Riviere P,Lanman RB,Kelly KJ,Veerapong J,Lowy AM,Kurzrock R

    更新日期：2020-09-01 00:00:00

  • The role of radiation therapy after nipple-sparing mastectomy.

    abstract：PURPOSE:The aim of this review was to examine the incidence of nipple-areola complex (NAC) involvement, the rates of NAC recurrence, and the data regarding the role of radiation therapy (RT) following nipple-sparing mastectomy (NSM). METHODS:A literature review was performed using the PubMed search engine, with articl...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,评审

    doi：10.1245/s10434-013-3446-z

    authors： Gomez C,Shah C,McCloskey S,Foster N,Vicini F

    更新日期：2014-07-01 00:00:00

  • Lymph node ratio: role in the staging of node-positive colon cancer.

    abstract：BACKGROUND:Recent literature has shown that lymph node ratio (LNR) is superior to the number of positive lymph nodes (pLNs) in predicting the prognosis in several malignances other than colon cancer. We hypothesize that LNR may play a similar role in stage III colon cancer. METHODS:We included 24,477 stage III colon c...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-007-9716-x

    authors： Wang J,Hassett JM,Dayton MT,Kulaylat MN

    更新日期：2008-06-01 00:00:00