Neuronal osmotransduction: push-activating TRPV1 with microtubules.

Abstract:

:Regulating the osmotic pressure of our body fluids relies on osmosensory neurons that depolarize when their volume decreases. Recently in Neuron, Prager-Khoutorsky et al. (2014) report that this depolarization arises from direct interactions between the transient receptor potential channel TRPV1 and microtubules, which seem to directly push open the channel.

journal_name

Dev Cell

journal_title

Developmental cell

authors

Andrés M,Göpfert MC

doi

10.1016/j.devcel.2014.08.012

subject

Has Abstract

pub_date

2014-08-25 00:00:00

pages

363-4

issue

4

eissn

1534-5807

issn

1878-1551

pii

S1534-5807(14)00522-X

journal_volume

30

pub_type

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