Abstract:
:Retrotransposons constitute a major part of the genome in a number of eukaryotes. Long-terminal repeat (LTR) retrotransposons are one type of the retrotransposons. Candida albicans have 34 distinct LTR-retrotransposon families. They respectively belong to the Ty1/copia and Ty3/gypsy groups which have been extensively studied in the model yeast Saccharomyces cerevisiae. LTR-retrotransposons carry two LTRs flanking a long internal protein-coding domain, open reading frames. LTR-retrotransposons use RNA as intermediate to synthesize double-stranded DNA copies. In this article, we describe the structure feature, retrotransposition mechanism and the influence on organism diversity of LTR retrotransposons in C. albicans. We also discuss the relationship between pathogenicity and LTR retrotransposons in C. albicans.
journal_name
Virulencejournal_title
Virulenceauthors
Zhang L,Yan L,Jiang J,Wang Y,Jiang Y,Yan T,Cao Ydoi
10.4161/viru.32180subject
Has Abstractpub_date
2014-08-15 00:00:00pages
655-64issue
6eissn
2150-5594issn
2150-5608pii
32180journal_volume
5pub_type
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