Abstract:
:Restriction factors are host cell proteins that inhibit retroviral infection. A new study using mutants of human HIV-1 restriction factor SAMHD1 suggests that it inhibits infection through degradation of viral RNA rather than through its dNTPase activity as previously suggested.
journal_name
Nat Medjournal_title
Nature medicineauthors
Yang Z,Greene WCdoi
10.1038/nm.3657subject
Has Abstractpub_date
2014-08-01 00:00:00pages
808-9issue
8eissn
1078-8956issn
1546-170Xpii
nm.3657journal_volume
20pub_type
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