Methicillin-resistant Staphylococcus aureus pneumonia in adults.

abstract：:Sarcoidosis is a multisystem disease for which diagnosis relies on the integration of clinical, radiologic, laboratory, and pathologic information. Assessment of clinical features is an important part of the disease evaluation. Computer Tomography provides information not available on routine chest roentgenogram which...

journal_title：Expert review of respiratory medicine

authors： Zhou Y,Lower EE,Li H,Baughman RP

更新日期：2016-01-01 00:00:00

abstract：:Studies on cough have come a long way but many shortfalls still exist. These shortfalls can be attributed to: the lack of randomized controlled studies with a focus on cough; studies not using robust cough outcome measures, poor definition of target groups in studies and guidelines, the lack of safe and efficacious tr...

journal_title：Expert review of respiratory medicine

authors： Chang AB

更新日期：2011-08-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by persistent airflow limitation. It is the third leading cause of death worldwide, and there are currently no curative strategies for this disease. Many factors contribute to COPD susceptibility, progression and exacerbations. These...

journal_title：Expert review of respiratory medicine

authors： Goh F,Shaw JG,Savarimuthu Francis SM,Vaughan A,Morrison L,Relan V,Marshall HM,Dent AG,O'Hare PE,Hsiao A,Bowman RV,Fong KM,Yang IA

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Approximately 14% of UK hospital in-patients receive supplemental oxygen therapy, only 57% have valid prescriptions. Oxygen must be optimally prescribed to ensure maximal therapeutic response whilst minimizing adverse outcomes (including fatality). This study investigates prescription compliance. METHODS:Al...

journal_title：Expert review of respiratory medicine

authors： Barrett R,Catangui E,Scott R

更新日期：2020-10-14 00:00:00

abstract：:Patients suffering from COPD not controlled by a single bronchodilator should be given two bronchodilators with different mechanisms of action. Addition of a LABA to a LAMA induces a larger bronchodilation than that obtained with the LAMA as monotherapy and also improves many patient-reported outcomes. Since the clini...

journal_title：Expert review of respiratory medicine

authors： Calzetta L,Ciaprini C,Puxeddu E,Cazzola M

更新日期：2016-04-01 00:00:00

abstract：:Despite marginal improvements in survival gained from multimodality treatment, long-term survival rates remain low for lung cancer, which remains the leading cause of cancer-related mortality in North America. BLP25 liposomal (L-BLP25) vaccine (Stimuvax) is a promising liposomal vaccine designed to generate an immune ...

journal_title：Expert review of respiratory medicine

authors： Powell E,Chow LQ

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The aim of this pilot study was to determine the combined effect of vitamin D and omega-3 polyunsaturated fatty acid (PUFA) supplementation on airway function and inflammation in recreational athletes with exercise-induced bronchoconstriction (EIB). METHODS:Ten recreational athletes with EIB participated in ...

journal_title：Expert review of respiratory medicine

authors： Price OJ,Hull JH,Howatson G,Robson-Ansley P,Ansley L

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:The independent and central role of the patient with a complex chronic respiratory disease in targeted, personalized disease management strategies is becoming increasingly important. Patients are the ones living with the disease and are finally responsible for their lives underlining their role as essentia...

journal_title：Expert review of respiratory medicine

authors： Houben-Wilke S,Augustin IM,Wouters BB,Stevens RA,Janssen DJ,Spruit MA,Vanfleteren LE,Franssen FM,Wouters EF

更新日期：2017-12-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a very common disease all around the world and has become an increasing public health concern to the Chinese medical community. In the past decades, telehealthcare technology has become a good way to manage COPD but current evidence makes it hard to determine the effecti...

journal_title：Expert review of respiratory medicine

authors： Lao X,Zhang J,Bai C

更新日期：2013-10-01 00:00:00

abstract：:Dendritic cells (DCs) are the most potent antigen-presenting cells in the human lung and are now recognized as crucial initiators of immune responses in general. They are arranged as sentinels in a dense surveillance network inside and below the epithelium of the airways and alveoli, where they are ideally situated to...

journal_title：Expert review of respiratory medicine

authors： Blank F,von Garnier C,Obregon C,Rothen-Rutishauser B,Gehr P,Nicod L

更新日期：2008-04-01 00:00:00

abstract：:Allergic airway disease is a major global health burden, and novel treatment options are urgently needed. Numerous epidemiological and experimental studies suggest that certain helminths and bacteria protect against respiratory allergies. These microorganisms are strong regulators of the immune system, and various pot...

journal_title：Expert review of respiratory medicine

authors： Obieglo K,van Wijck Y,de Kleijn S,Smits HH,Taube C

更新日期：2014-12-01 00:00:00

abstract：:In 2007 the long-term outcome of lung cancer is still disappointing, with a 5-year survival rate not exceeding 15%. However, small but significant improvements in survival times have been achieved in the last decade. This progress has been achieved through the improvement of surgical techniques and following the intro...

journal_title：Expert review of respiratory medicine

authors： Selvaggi G,Scagliotti GV

更新日期：2007-08-01 00:00:00

abstract：INTRODUCTION:Paediatric severe therapy resistant asthma (STRA) affects a very small proportion of all children with asthma, but results in significant morbidity, has a high risk of mortality and utilises approximately half of all healthcare resources for childhood asthma. children with STRA need add-on 'beyond guidelin...

journal_title：Expert review of respiratory medicine

authors： Martin Alonso A,Fainardi V,Saglani S

更新日期：2017-11-01 00:00:00

abstract：:Introduction: Cystic fibrosis (CF) is a complex, multi-system, genetic disease affecting over 70,000 people worldwide. The underlying defect is a mutation in the CFTR gene. Dysfunctional CFTR protein results in abnormal anion movement across epithelial membranes in affected organs. There has been a paradigm shift in C...

journal_title：Expert review of respiratory medicine

authors： Paterson SL,Barry PJ,Horsley AR

更新日期：2020-01-01 00:00:00

abstract：:Some basic scientific data suggest that (S)-enantiomers of beta(2)-agonists have different and sometimes opposing effects to (R)-enantiomers. These data may explain the paradoxical response of the airways to the repeated, chronic administration of racemic beta(2)-agonists. Therefore, it is possible that the use of (R)...

journal_title：Expert review of respiratory medicine

authors： Cazzola M,Hanania NA,Matera MG

更新日期：2010-04-01 00:00:00

abstract：:Non-small-cell lung cancer is the most common cause of cancer-related death worldwide. Surgery remains the cornerstone of treatment for localized, resectable lung cancer, although advanced stages are associated with a high risk of developing distant metastases. Large randomized trials have demonstrated an improvement ...

journal_title：Expert review of respiratory medicine

authors： Kueng MM,Betticher DC

更新日期：2008-10-01 00:00:00

abstract：:Smoke inhalation injury continues to increase morbidity and mortality in burn patients in both the third world and industrialized countries. The lack of uniform criteria for the diagnosis and definition of smoke inhalation injury contributes to the fact that, despite extensive research, mortality rates have changed li...

journal_title：Expert review of respiratory medicine

authors： Rehberg S,Maybauer MO,Enkhbaatar P,Maybauer DM,Yamamoto Y,Traber DL

更新日期：2009-06-01 00:00:00

abstract：:Caveolin-1 (Cav-1) is the major protein present in invaginations of the plasma membrane of cells known as caveolae. Cav-1 is expressed in numerous resident and inflammatory cells implicated in the pathogenesis of asthma and chronic inflammatory respiratory diseases including chronic obstructive pulmonary disease. A re...

journal_title：Expert review of respiratory medicine

authors： Royce SG,Le Saux CJ

更新日期：2014-06-01 00:00:00

abstract：INTRODUCTION:Lung Clearance Index, measured using the multiple breath washout (MBW) technique, may be a useful test in infants with Cystic Fibrosis (CF). However, the requirement for specialised equipment and a number of important technical and methodological considerations relevant to testing in infants have complicat...

journal_title：Expert review of respiratory medicine

authors： Davies G,Aurora P

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Non-small cell lung cancer patients harboring uncommon epidermal growth factor receptor (EGFR) mutations together account for approximately 10% of all EGFR mutations. The most common of which being G719X, S768I, L861Q, and exon 20 insertions. The clinical significance, particularly their response to EGFR t...

journal_title：Expert review of respiratory medicine

authors： Wu TH,Hsiue EH,Lee JH,Lin CC,Yang JC

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Pleural disease encompasses a large range of conditions, is a common presentation to the acute medical take and often requires comprehensive investigation and treatment. Ultrasound is well recognised as a useful investigative tool in pleural disease especially in the field of pleural effusion, pleural thic...

journal_title：Expert review of respiratory medicine

authors： Mercer RM,Psallidas I,Rahman NM

更新日期：2017-04-01 00:00:00

abstract：:Asthma is a disease that affects approximately 7% of adults residing in the USA; the prevalence is even greater in children and approaches 10%. The CDC has reported that the overall prevalence of lifetime asthma is 10.5%. New-onset asthma is most often seen in children and is associated with atopy; however, the majori...

journal_title：Expert review of respiratory medicine

authors： Braman SS

更新日期：2010-04-01 00:00:00

abstract：:Innovations in surgery have significantly increased the number of procedures performed every year. While more individuals benefit from better surgical techniques and technology, a larger group of patients previously deemed ineligible for surgery now undergo high-complexity surgical procedures. Despite continuous impro...

journal_title：Expert review of respiratory medicine

authors： Restrepo RD,Braverman J

更新日期：2015-02-01 00:00:00

abstract：:The hallmarks of allergic bronchial asthma arise from chronic airway inflammation. Thus, elucidating the mechanisms regulating the maintenance of this chronic inflammatory response is key to understanding asthma pathogenesis. To date, it is not clear whether a predominance of proinflammatory factors or a reduced capac...

journal_title：Expert review of respiratory medicine

authors： Lunding L,Schröder A,Wegmann M

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Interstitial lung diseases (ILD) include a broad range of diffuse parenchymal lung disorders of known and unknown etiologies. Patients with ILD can experience acute exacerbations (AE) which are associated with extremely high morbidity and mortality. Little is known about the etiology of AEs, and whether in...

journal_title：Expert review of respiratory medicine

authors： Azadeh N,Moua T,Baqir M,Ryu JH

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:The treatment of infection with Mycobacterium tuberculosis in young children is supported by universal policy based on strong rationale and evidence of effectiveness, but has rarely been implemented in tuberculosis endemic countries. Areas covered: This review highlights a number of important recent develo...

journal_title：Expert review of respiratory medicine

authors： Graham SM

更新日期：2017-01-01 00:00:00

abstract：:In many countries numbers of adults with cystic fibrosis (CF) exceed that of children, with median survival predicted to surpass 50 years. Increasing longevity is, in part, due to intensive therapies including eradication of early infection and suppressive therapies and pulmonary exacerbations. Initial infections with...

journal_title：Expert review of respiratory medicine

authors： Ramsay KA,Stockwell RE,Bell SC,Kidd TJ

更新日期：2016-01-01 00:00:00

abstract：:Chronic airway infection and inflammation are the hallmarks of cystic fibrosis (CF) lung disease. As these events occur early in life, it is critical to develop techniques for the assessment and monitoring of early-CF lung disease in infants and young children. In the last several years, there have been major advances...

journal_title：Expert review of respiratory medicine

authors： Ren CL

更新日期：2008-06-01 00:00:00

abstract：:Introduction: Amongst allergic asthmatics, high allergen exposure increases asthma severity. However, there is no consensus on the role of mite allergen avoidance in the management of asthma, and various guidelines differ in their recommendations. Areas covered: Several systematic reviews/meta-analyses on mite avoidan...

journal_title：Expert review of respiratory medicine

authors： Custovic A,Murray CS,Simpson A

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Acute exacerbations of chronic lung disease account for substantial morbidity and health costs. Repeated inflammatory episodes and attendant bronchoconstriction cause structural remodeling of the airway. Remodeling is a multicellular response to mucosal injury that results in epithelial cell-state changes,...

journal_title：Expert review of respiratory medicine

authors： Brasier AR

更新日期：2018-11-01 00:00:00