Changes in lipid composition of neuroblastoma C1300 N18 cell during differentiation.

abstract：:The hippocampus plays an important role in the formation of new memories and spatial navigation. Recently, growing evidence supports the view that it is also involved in addiction to opiates and other drugs. Theoretical and experimental studies suggest that hippocampal neural-network oscillations at specific frequenci...

journal_title：Neuroscience

authors： Liu F,Jiang H,Zhong W,Wu X,Luo J

更新日期：2010-12-15 00:00:00

abstract：:Necrostatin-1 (Nec-1) is an inhibitor of necroptosis, playing an important role in inhibition of pathological death in the central nervous system (CNS). Our earlier study suggests that Nec-1 protects the injured spinal cord. In this study, we found that Nec-1 reduces the elevated Ca(2+) concentration in mitochondria p...

journal_title：Neuroscience

authors： Wang Y,Wang J,Yang H,Zhou J,Feng X,Wang H,Tao Y

更新日期：2015-03-19 00:00:00

abstract：:Many of the different morphological types of interneurons in mammalian neocortex are presumed to be inhibitory, but to date, conclusive functional data have been lacking. Using paired intracellular recordings in slices of adult rat somatosensory cortex, we present a sparsely spiny, burst firing interneuron that elicit...

journal_title：Neuroscience

authors： Deuchars J,Thomson AM

更新日期：1995-04-01 00:00:00

abstract：:Our aim was to evaluate continuous theta burst stimulation (cTBS) as a tool to induce temporary impairment (virtual lesion) in semantic processing. Four groups with 20 subjects each were stimulated. In the three experimental groups the stimulation site was the left superior temporal cortex. Stimulation was either 1Hz ...

journal_title：Neuroscience

authors： Brückner S,Kiefer M,Kammer T

更新日期：2013-03-13 00:00:00

abstract：:Nerve growth factor (NGF) synthesized in peripheral organs plays a critical role in the development and maintenance of the nervous system and also participates in processing nociceptive stimuli. Previous studies suggest that reproductive hormones may regulate the expression of NGF. Ovariectomies were performed on fema...

journal_title：Neuroscience

authors： Bjorling DE,Beckman M,Clayton MK,Wang ZY

更新日期：2002-01-01 00:00:00

abstract：:Extensive studies have shown that a sports expert is superior to a sports novice in visually perceptual-cognitive processes of sports scene information, however the attentional and neural basis of it has not been thoroughly explored. The present study examined whether a sport expert has the attentional superiority on ...

journal_title：Neuroscience

authors： He M,Qi C,Lu Y,Song A,Hayat SZ,Xu X

更新日期：2018-05-21 00:00:00

abstract：:S100beta is a calcium-binding peptide produced mainly by astrocytes that exerts paracrine and autocrine effects on neurons and glia. We have previously shown that S100beta is markedly elevated at the mRNA level in the spinal cord following peripheral inflammation, intraplantar administration of complete Freund's adjuv...

journal_title：Neuroscience

authors： Tanga FY,Raghavendra V,Nutile-McMenemy N,Marks A,Deleo JA

更新日期：2006-07-07 00:00:00

abstract：:The distribution, structural organization and state of phosphorylation of neurofilaments have been examined in chromaffin cells from adult bovine adrenal medulla cultured under various conditions using a series of monoclonal antibodies directed against phosphorylated and nonphosphorylated epitopes of the 200,000 mol. ...

journal_title：Neuroscience

authors： Grant NJ,Demeneix B,Aunis D,Langley OK

更新日期：1988-11-01 00:00:00

abstract：:Scratching inhibits pruritogen-evoked responses of neurons in the superficial dorsal horn, implicating a spinal site for scratch inhibition of itch. We investigated if scratching differentially affects neurons depending on whether they are activated by itchy vs. painful stimuli, and if the degree of inhibition depends...

journal_title：Neuroscience

authors： Nishida K,Takechi K,Akiyama T,Carstens MI,Carstens E

更新日期：2013-10-10 00:00:00

abstract：:The effects of two benzodiazepines, diazepam and triazolam, on long-term potentiation were tested in slices of hippocampus and piriform cortex. The drugs had little influence on baseline synaptic responses but both were very effective in blocking LTP elicited by theta pattern stimulation. The effects were fully revers...

journal_title：Neuroscience

authors： del Cerro S,Jung M,Lynch G

更新日期：1992-07-01 00:00:00

abstract：:Miniature endplate potentials were recorded from edge muscle fibers of frog sartorius muscles during high frequencies induced with K-propionate and during recovery. The identified neuromuscular junctions were studied with the electron microscope and their ultrastructure was correlated with amplitude and numbers of min...

journal_title：Neuroscience

authors： Florey E,Kriebel ME

更新日期：1988-12-01 00:00:00

abstract：:The effect of muscarinic agonists on the spontaneous release of [3H]GABA was investigated in vitro on rat substantia nigra slices. Acetylcholine (5 x 10(-5) M) in the presence of eserine (5 x 10(-5) M) induced a 12.3% increase of the spontaneous release of [3H]GABA. Similarly, carbachol (5 x 10(-4) M) enhanced by 9% t...

journal_title：Neuroscience

authors： Kayadjanian N,Gioanni H,Ménetrey A,Besson MJ

更新日期：1994-12-01 00:00:00

abstract：:The functional changes of astrocytes are deeply involved in neurodegenerating processes of various CNS diseases. ATP is released during various neuronal damages such as brain ischemia and may control astrocyte functions. We examined the effect of ATP on the production of nitric oxide in the cultured astrocytes from ra...

journal_title：Neuroscience

authors： Murakami K,Nakamura Y,Yoneda Y

更新日期：2003-01-01 00:00:00

abstract：:In several tauopathies such as Alzheimer's disease (AD), an increased incidence of seizures is observed. Tau, one of the major proteins implicated in AD pathology, is an important regulator of neural network excitability and might participate in the underlying epileptic cascade. However, the mechanisms underlying this...

journal_title：Neuroscience

authors： Van Erum J,Valkenburg F,Van Dam D,De Deyn PP

更新日期：2020-01-15 00:00:00

abstract：:Creatine supplementation has been shown to protect neurons from oxidative damage due to its antioxidant and ergogenic functions. These features have led to the hypothesis of creatine supplementation use during pregnancy as prophylactic treatment to prevent CNS damage, such as hypoxic-ischemic encephalopathy. Unfortuna...

journal_title：Neuroscience

authors： Sartini S,Lattanzi D,Ambrogini P,Di Palma M,Galati C,Savelli D,Polidori E,Calcabrini C,Rocchi MB,Sestili P,Cuppini R

更新日期：2016-01-15 00:00:00

abstract：:GABAergic neurons occur in the myenteric plexus and submucosa and their innervations of the gut, where GABA stimulates motor neurons, and non-neural cells via "central type" GABA(A) receptors. These receptors occur on half of the neurons in the rat intestine. The GABA(A) receptor is a ligand-gated chloride channel con...

journal_title：Neuroscience

authors： Poulter MO,Singhal R,Brown LA,Krantis A

更新日期：1999-01-01 00:00:00

abstract：:Agrin, a synaptic basal lamina protein, is essential for the formation of the vertebrate neuromuscular junction. Agrin's role in synaptogenesis in the central nervous system has, however, not been elucidated. Therefore, we performed immunohistochemical analysis of agrin localization in adult rat brain using agrin-spec...

journal_title：Neuroscience

authors： Cohen NA,Kaufmann WE,Worley PF,Rupp F

更新日期：1997-01-01 00:00:00

abstract：:To investigate the degree of plasticity of hippocampal neural stem cells from adult mice (mHNSC), we have analyzed their differentiation in co-culture with quail neural crest cells. In mixed culture, mHNSC give rise to several non-neuronal neural crest derivatives, including melanocytes, chondrocytes and smooth muscle...

journal_title：Neuroscience

authors： Alexanian AR,Sieber-Blum M

更新日期：2003-01-01 00:00:00

abstract：:Neonatal inhibition of brain estrogen formation in male rats by administration of the aromatase inhibitor, 1,4,6-androstatriene-3,17-dione (ATD), permanently changes aspects of their mating behavior and partner preference in adulthood. The medial preoptic area receives chemosensory inputs via a sexually dimorphic vome...

journal_title：Neuroscience

authors： Bakker J,Baum MJ,Slob AK

更新日期：1996-09-01 00:00:00

abstract：:Adrenalectomy (ADX) abolishes behavioral sensitization to cocaine in DBA/2, but not C57BL/6 inbred mice. The present study tests the hypothesis that this ADX effect on behavioral sensitization in the DBA/2 strain involves changes in midbrain dopamine systems that do not occur in the C57BL/6 strain. For that purpose, w...

journal_title：Neuroscience

authors： de Jong IE,Steenbergen PJ,de Kloet ER

更新日期：2008-05-15 00:00:00

abstract：:Linear sweep voltammograms recorded with carbon paste electrodes in the striatum of the unanaesthetised, unrestrained rat show three separate peaks. The effect on peak 3 of either unilateral 6-hydroxydopamine lesion of the substantia nigra or intraperitoneal administration of alpha-methyl-paratyrosine, supports our ea...

journal_title：Neuroscience

authors： O'Neill RD,Fillenz M

更新日期：1985-03-01 00:00:00

abstract：:The effects of hypothermia on ischemia-reperfusion injury of the cochlea were studied in gerbils. Hearing was assessed by sequentially recording compound action potentials before, during and after the ischemia. The degree of hair cell loss in the organ of Corti was evaluated in specimens stained with rhodamine-phalloi...

journal_title：Neuroscience

authors： Watanabe F,Koga K,Hakuba N,Gyo K

更新日期：2001-01-01 00:00:00

abstract：:The electrophysiological, biochemical and behavioral responses produced by administration of haloperidol were studied in intact rats and in rats with 6-hydroxydopamine-induced partial lesions of the nigrostriatal dopamine pathway. In both control rats and rates tested four to 10 days postlesion, the electrophysiologic...

journal_title：Neuroscience

authors： Hollerman JR,Abercrombie ED,Grace AA

更新日期：1992-01-01 00:00:00

abstract：:Several genetic mutations affecting the development and function of mammalian hair cells have been shown to cause deafness but not vestibular defects, most likely because vestibular deficits are sometimes centrally compensated. The study of hair cell physiology is thus a powerful direct approach to ascertain the funct...

journal_title：Neuroscience

authors： Tavazzani E,Spaiardi P,Zampini V,Contini D,Manca M,Russo G,Prigioni I,Marcotti W,Masetto S

更新日期：2016-07-22 00:00:00

abstract：:Before movement onset, during the reaction time, excitability of M1 is selectively modulated by somatosensory inputs, only in the movement-related muscle. If a similar mechanism operates before the onset of mental movements, then somatosensory afferent inputs are exploited during cognitive representation of movement. ...

journal_title：Neuroscience

authors： Bonassi G,Bisio A,Lagravinese G,Ruggeri P,Bove M,Avanzino L

更新日期：2019-06-15 00:00:00

abstract：:Basic parameters which are crucial for the survival of human embryonic striatal grafts need to be investigated before initiating clinical trials in Huntington's disease. In order to define the dissection of human striatal-donor tissue which gives rise to the largest amount of striatal neurons after intrastriatal trans...

journal_title：Neuroscience

authors： Grasbon-Frodl EM,Nakao N,Lindvall O,Brundin P

更新日期：1996-07-01 00:00:00

abstract：:It was investigated whether grafts of the suprachiasmatic nucleus could re-instate circadian rhythmicity in the absence of its endogenous vasopressin production and whether the restored rhythm would have the long period length of the donor. Grafts of 17-days-old vasopressin-deficient homozygous Brattleboro rat fetuses...

journal_title：Neuroscience

authors： Boer GJ,van Esseveldt KE,van der Geest BA,Duindam H,Rietveld WJ

更新日期：1999-03-01 00:00:00

abstract：:Amyloid-β (Aβ) production and clearance in the brain is a crucial focus of investigations into the pathogenesis of Alzheimer disease. Imbalance between production and clearance leads to accumulation of Aβ. The important Aβ-degrading enzymes in the brain are neprilysin (NEP) and insulin-degrading enzyme (IDE), and defe...

journal_title：Neuroscience

authors： Yamamoto N,Shibata M,Ishikuro R,Tanida M,Taniguchi Y,Ikeda-Matsuo Y,Sobue K

更新日期：2017-10-24 00:00:00

abstract：:The primary visual (V1), auditory (AI), and somatosensory (SI) cortices are reciprocally connected with their respective sensory association cortices. In the rat, we have previously demonstrated that some of the connections arising from the secondary somatosensory (SII) and parietal insular (PA) cortices and terminati...

journal_title：Neuroscience

authors： Bai WZ,Ishida M,Arimatsu Y

更新日期：2004-01-01 00:00:00

abstract：:Paclitaxel is one of the most commonly used anti-neoplastic drugs for the treatment of solid tumors. Unfortunately, its use is often associated with dose-limiting painful peripheral neuropathy and subsequent neuropathic pain that is resistant to standard analgesics. However, there are few clinically available drugs or...

journal_title：Neuroscience

authors： Kiya T,Kawamata T,Namiki A,Yamakage M

更新日期：2011-02-03 00:00:00