Abstract：
:Ionic liquids (ILs), entirely composed of cations and anions, are liquid solvents at room temperature. They are interesting due to their low vapor pressure, high polarity and thermostability, and also for the possibility to fine-tune their physicochemical properties through modification of the chemical structures of their cations or anions. In recent years, ILs have been widely used in biotechnological fields involving whole-cell biotransformations of biodiesel or biomass, and organic compound synthesis with cells. Research studies in these fields have increased from the past decades and compared to the typical solvents, ILs are the most promising alternative solvents for cell biotransformations. However, there are increasing limitations and new challenges in whole-cell biotransformations with ILs. There is little understanding of the mechanisms of ILs' interactions with cells, and much remains to be clarified. Further investigations are required to overcome the drawbacks of their applications and to broaden their application spectrum. This work mainly reviews the applications of ILs in whole-cell biotransformations, and the possible mechanisms of ILs in microbial cell biotransformation are proposed and discussed.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Fan LL,Li HJ,Chen QHdoi
10.3390/ijms150712196subject
Has Abstractpub_date
2014-07-09 00:00:00pages
12196-216issue
7issn
1422-0067pii
ijms150712196journal_volume
15pub_type
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更新日期：2013-06-28 00:00:00
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更新日期：2013-09-06 00:00:00
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