Supersusceptibility to hydrophobic antimicrobial agents and cell surface hydrophobicity in Branhamella catarrhalis.

Abstract:

:To clarify the cause of the supersusceptibility of Branhamella catarrhalis to macrolide antibiotics, which are well-known to be inactive to most Gram-negative bacteria, we determined its cell surface hydrophobicity by the partition experiment between water and hydrocarbons. Its cell surface was found to be markedly more hydrophobic than that of Escherichia coli or Pseudomonas aeruginosa cells. This suggested that the outer membrane of B. catarrhalis plays no role as a diffusion barrier towards hydrophobic agents.

journal_name

FEMS Microbiol Lett

authors

Gotoh N,Tanaka S,Nishino T

doi

10.1016/0378-1097(89)90488-6

subject

Has Abstract

pub_date

1989-05-01 00:00:00

pages

211-3

issue

1-2

eissn

0378-1097

issn

1574-6968

journal_volume

50

pub_type

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