Improvement in symptoms and cochlear flow with pycnogenol in patients with Meniere's disease and tinnitus.

Abstract:

AIM:The aim of this supplement registry was to evaluate the efficacy of the Pycnogenol® in improving cochlear flow and symptoms in a 6-month follow-up for patients with Meniere's disease (MD), tinnitus and cochlear hypoperfusion. METHODS:Main signs/symptoms were considered: Spontaneous vertigo, positional vertigo, hearing loss, tinnitus, pressure in the ear, unsteady gait, associated clinical problems, alterations in daily life. All subjects were managed with the best available management (BM); one group used the supplement Pycnogenol (150 mg/day). Cochlear flow and tinnitus were also evaluated. Out of 120 patients incuded in the registry, 55 used Pycnogenol and 52 (controls) were managed only with BM. RESULTS:There was a more significant improvement in all registry items at 3 and 6 months in the Pycnogenol group (P<0.05). The number of lost working days was lower in the Pycnogenol group. At 3 months, 45.4% of subjects using Pycnogenol were completely asymptomatic in comparison with 23.07% of controls. At 6 months 87.3% of the Pycnogenol subjects were asymptomatic compared with 34.6% of controls. Cochlear flow velocity was significantly better (higher flow, higher diastolic component) in the Pycnogenol group (P<0.05). The subjective tinnitus scale decreased in both groups (P<0.05); the decrease was more significant in Pycnogenol subjects (P<0.05) at 3 and 6 months. CONCLUSION:Symptoms of Meniere's disease, flow at cochlear level and tinnitus improved in Pycnogenol subjects in comparison with best management.

journal_name

Minerva Med

journal_title

Minerva medica

authors

Luzzi R,Belcaro G,Hu S,Dugall M,Hosoi M,Cacchio M,Ippolito E,Corsi M

subject

Has Abstract

pub_date

2014-06-01 00:00:00

pages

245-54

issue

3

eissn

0026-4806

issn

1827-1669

pii

R10Y2014N03A0245

journal_volume

105

pub_type

杂志文章
  • [2 cases of toxic epidermal necrolysis or Lyell's syndrome].

    abstract::Two cases of Lyell's syndrome (toxic necrolysis of the epidermis) are reported on account of their rarity. The differential diagnosis of this form and its aetiopathogenesis and treatment are described. ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Barbanera M,Menicagli V,Pardelli GC

    更新日期:1975-12-15 00:00:00

  • [Chronic bronchopneumopathies in chest x-ray findings at the Centro di Medicina Preventiva e Sociale].

    abstract::Screening of secundary school children and the general opulation of the V. Monaldi Hospital Preventive and Social Medicine Centre,Naples showed a by no means negligible incidence of chronic bronchopneumopathy, particulary in infants. It is felt that, if untreated, these forms may be responsible for chronic respiratory...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Brancaccio M,Cocciante B

    更新日期:1975-03-21 00:00:00

  • [Endoscopic study on the gastric tolerance of antalgic-antirheumatic substances:parsalmide].

    abstract::The gastric tolerance of parsalmide, a new analgesic, antirheumatic and sedative substance was tested on a group of 50 arthrorheumatic patients with the purpose of assessing gastric damage if any. It was also compared with the tolerance of the better known antitrheumatic drugs in current use. The study was conducted w...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Mirelli E,Fichera G,Boidi G

    更新日期:1976-10-31 00:00:00

  • [Clinico-functional respiratory assessment of the athlete with exercise-induced asthma or bronchospasm].

    abstract::Asthmatic subjects can only be allowed to take part in sport activities after a careful functional evaluation of pulmonary function. For sport disciplines which require a mainly anaerobic metabolism it is enough to evaluate the respiratory function at rest, while for sport disciplines which require a mainly aerobic me...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Romano A,Canino B,Lo Presti R,Oddo G,Sarno A,Caimi G

    更新日期:1998-09-01 00:00:00

  • [Clinico-statistical and medico-social considerations on giant uterine fibromyomatosis].

    abstract::Observations in the past decade in Veneto and Calabrian hospitals of cases of advanced pathology such as giant uterine fibromas suggest some clinico-statistical and medico-social considerations. ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Giannice C

    更新日期:1981-04-21 00:00:00

  • Is the pattern of liver disease etiology changing in China?

    abstract:: ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:10.23736/S0026-4806.19.06102-0

    authors: Caviglia GP,Rosso C

    更新日期:2019-05-06 00:00:00

  • Anxiety and depression in cystic fibrosis.

    abstract::Cystic fibrosis (CF) is the most common genetic disorders in the Caucasian population, with estimated between 70,000 and 100,000 patients worldwide. Even if improved diagnostics and clinical management have led to an increased life expectancy, CF still remains a disease that significantly impacts patients' life in ter...

    journal_title:Minerva medica

    pub_type: 杂志文章,多中心研究,评审

    doi:

    authors: Baiardini I,Steinhilber G,DI Marco F,Braido F,Solidoro P

    更新日期:2015-10-01 00:00:00

  • [Unilateral pulmonary edema due to rapid re-expansion in pneumothorax].

    abstract::A case of unilateral pulmonary oedema (UPO) caused by rapid re-expansion after drainage of a spontaneous pneumothorax is reported. If acute respiratory failure is noted at the moment of re-expansion the condition can be brought within safe limits by careful clinical observation and if necessary the use of assisted res...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Parisi A,Marianeschi PM,Giustozzi GM,Bellavigna G,Alberti D,Sciannameo F

    更新日期:1986-12-22 00:00:00

  • Improving donor lung suitability: from protective strategies to ex-vivo reconditioning.

    abstract::Lung transplant is a therapeutic option for end stage lung diseases, but only a limited number of lung grafts is considered suitable for transplantation. It has been recently suggested an approach to improve and maximize donor lung suitability, namely ventilation strategies to prevent lung damage and preserve function...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Solidoro P,Schreiber A,Boffini M,Braido F,DI Marco F

    更新日期:2016-06-01 00:00:00

  • Usable donor lungs: exploring the hidden part of the iceberg.

    abstract::Lung transplantation (LTx) remains the only effective treatment of selected patients suffering from end-stage respiratory disease. However, its main limitation is represented by the shortage of suitable organs. In the last years, LTx is progressively changing in the clinical arena and different strategies aiming to in...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Boffini M,Solidoro P

    更新日期:2014-02-01 00:00:00

  • [The role of penile Doppler sonography in impotent diabetics].

    abstract::Penile systolic pressure has been evaluated by the Doppler-sonographic method in 15 diabetic patients suffering from erectile impotence. Urodynamic tests have also been carried out in some patients for a diagnosis of neurological impotence. The results obtained show the possibility of a double or sole origin (neurogen...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Giordanengo F,Pignoli P,De Carlis L,Soleri V,Franch L

    更新日期:1981-12-08 00:00:00

  • [Friedreich's disease, diabetes and pregnancy. Description of a case].

    abstract::Birth of an infant at term to a diabetic woman with a severe form of Friedreich's disease is reported. The aetiopathogenesis of the cardiac deformities that led to the death of the child on day seven of life is discussed. ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Moneta E,Cocchi A,Scoppetta C

    更新日期:1976-02-11 00:00:00

  • [Role of hypnosis in psychosomatic medicine].

    abstract::In Italy, the attitude displayed by psychosomatists towards hypnosis and A.T. is decidedly favourable, since they are considered as forms of short-term psychotherapy, this being primarily indicated in the management of psychosomatosis. While some reservations may be expressed with regard to the employment of hypnosis ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Antonelli F

    更新日期:1975-10-31 00:00:00

  • [Chronobiology of dynamic equilibrium and recurrence of migraine crises].

    abstract::Haemodynamic balance was assessed in relation to platelet-vessel homeostasis in the microcirculation in a group of 15 migraine sufferers and 15 healthy subjects. The results support the hypothesis of a relationship between the typical recurrence of migraine attacks and the chronobiological performance of the haemodyna...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: D'Attoma G,Marconi G,Nacci MG

    更新日期:1986-07-31 00:00:00

  • [Statistical approach to psychosomatic headaches].

    abstract::Three groups of patients were compared statistically: 79 with the diagnosis psychosomatic headache' (in the strict sense of the term), 450 others whose headache was part of another disorder (termed symptomatic headache'), and 850 patients free from headache symptoms. The following characteristics were found for the gr...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Timsit M,Urbain E,Sabatier J,Timsit-Berthier M

    更新日期:1976-06-23 00:00:00

  • Spinal antinflammatory action of Diclofenac.

    abstract::Diclofenac is a non-steroidal antinflammatory drug (NSAID) that finds indication in the treatment of debilitating pathologies characterized by chronic pain sustained by inflammation, such as in rheumatic disease (rheumatoid arthritis or osteoarthritis) or periarthritis, bursitis, tendonitis, myositis and sciatica. Its...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Sandri A

    更新日期:2016-06-01 00:00:00

  • [Diagnostic and therapeutic studies using the cryoprobe in various forms of facial pain, not of the migraine or trigeminal type].

    abstract::The application of cold in neurosurgery (cryosurgery) has already clearly shown that it acts on the nervous structures in two opposite directions, depending on the temperature: i.e., at temperature from 0 degrees to --10 degrees, it stimulates the nervous fibres, and, at lower temperatures (below--80 degrees), it caus...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Fasano VA

    更新日期:1976-06-02 00:00:00

  • [The incidence, etiology and clinical significance of visceral mycoses in patients with AIDS].

    abstract::The incidence, aetiology and clinical significance of visceral mycoses in HIV-infected subjects were evaluated by a retrospective survey of the clinical and microbiological records of 237 consecutive AIDS patients followed-up since 1984. Seventy-four patients out of 237 (31.2%) (56 males, 18 females; 55 IV drug abuser...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Manfredi R,Nanetti A,Mazzoni A,Mastroianni A,Chiodo F

    更新日期:1993-07-01 00:00:00

  • The glaucomas.

    abstract::Glaucoma is the leading cause of irreversible blindness worldwide. The World Health Organization reported in 1995 that 5.1 million persons were bilaterally blind from glaucoma. Its morbidity and prevalence make it a significant public health problem. Because it is a treatable condition, it is important that medical pr...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Coleman AL,Brigatti L

    更新日期:2001-10-01 00:00:00

  • [Kinetics of breast neoplasms].

    abstract::Breast cancer is a disease moderately responsive to chemotherapy. While its curability is inversely related to the tumor burden, a relevant number of patients still progress to metastatic disease even after adjuvant chemotherapy. Also, high-dose chemotherapy appears promising, but can not yet be considered ultimately ...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Surbone A,Norton L

    更新日期:1994-01-01 00:00:00

  • A prognostic evaluation and management of alcoholic hepatitis.

    abstract::Alcoholic hepatitis (AH) is an acute and severe form of alco1holic liver disease associated with high morbidity and mortality of 30-50% worldwide, severity ranging from asymptomatic derangement of liver biochemistries to fulminant liver failure or death. Rapidly progressing jaundice and coagulopathy in prolonged exces...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:10.23736/S0026-4806.17.05136-9

    authors: Rana R,Wang SL,Li J,Xia L,Song MY,Yang CQ

    更新日期:2017-12-01 00:00:00

  • [The onset of double metachronous neoplasms 29 years after the diagnosis of Hodgkin's disease].

    abstract::The occurrence of two new cancers (a diffuse centrocytic lymphoma and a basal cell cancer) in a patient successfully treated for Hodgkin's disease 29 years before is reported. The centrocytic lymphoma mainly involved the skin, the basal cell carcinoma developed on the dorsum of the right hand. The patient had received...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Bisi D,Federico M,Sarti M,Barbieri F,Curci G

    更新日期:1989-05-01 00:00:00

  • [The value of echotomographic data in mesenteric cysts].

    abstract::The Authors report a case of chylous mesenteric cyst of great size in an adult patient. They stress the diagnostic value of roentgen and sonographic findings that are determinant for a correct preoperative diagnosis. Sonography is the most important diagnostic tool; it leads to identification and localization of the m...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Preziosi P,Gonella L,Cucchiara G

    更新日期:1982-12-15 00:00:00

  • [Adrenal cystic masses. Our experience].

    abstract::Cystic masses of the adrenal gland are clinically and pathologically rare findings and few cases have been reported up to now in the medical literature. In the present work 5 new cases are reported: 3 adrenal pseudocysts, 1 lymphangioma, 1 cystic pheochromocytoma. In 3 cases there were clinical symptoms of retroperito...

    journal_title:Minerva medica

    pub_type: 杂志文章,评审

    doi:

    authors: Costantino V,Petrin P,Da Lio C,Zaramella D,Pedrazzoli S

    更新日期:1993-10-01 00:00:00

  • [Differential diagnosis of fever of unknown origin. A case of adult onset Still disease].

    abstract:BACKGROUND:A case of Still's disease in the adult, an uncommon seronegative rheumatoid arthritis-like disease with prominent systemic features is reported. This case did not show the typical clinical features and appeared like a fever of unknown origin. CASE REPORT:A 60 year-old female was admitted to the hospital for...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Regoli G,Trotta M,Agostino I

    更新日期:1998-01-01 00:00:00

  • Emerging trends in cardiovascular research: HFpEF in the spotlight. A bibliometric analysis of the years 2009-2016.

    abstract:BACKGROUND:Up to 50% of patients suffering from acute decompensated heart failure show normal or slightly reduced left ventricular ejection fraction (LVEF). This syndrome, which is known as "heart failure with preserved ejection fraction" (HFpEF) is associated with increasing age. Epidemiological studies could portrait...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:10.23736/S0026-4806.20.06447-2

    authors: Edlinger C,Mösenlechner T,Krizanic F,Wernly B,Kretzschmar D,Hoppe UC,Butter C,Neuss M,Noutsias M,Granitz C,Schernthaner C,Wintersteller W,Lichtenauer M

    更新日期:2020-03-12 00:00:00

  • [Doping and sports].

    abstract::Doping is widely known as the use of banned substances and practices by athletes in an attempt to improve sporting performances. The term doping likely derives from "dope", an ancient expression referred to a primitive alcoholic drink that was used as a stimulant in South African ceremonial dances; gradually, the term...

    journal_title:Minerva medica

    pub_type: 历史文章,杂志文章,评审

    doi:

    authors: Lippi G,Guidi G

    更新日期:1999-09-01 00:00:00

  • [Cases of enuresis nocturna treated with single reflexotherapy. Clinical and therapeutic evaluation].

    abstract::Treatment of children with nocturnal enuresis by means of acupuncture, auriculotherapy, etc. is reported. The aetiopathogenetic background, the results of treatment, and the neurophysiological mechanisms through which the action of reflexotherapy can be explained are discussed. ...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Milani L

    更新日期:1976-11-24 00:00:00

  • [A case of thrombotic thrombocytopenic purpura].

    abstract::Thrombocytopenic thrombotic purpura is a comparatively rare disease and little is known about its aetiopathogenesis. Once almost invariably negative, the prognosis has been changed by the introduction of plasmapheresis. A particularly complex clinical case is described and a number of conclusions are drawn from it: 1)...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Meregalli M,Gambelli F,Torchio G,Bocchia M

    更新日期:1989-03-01 00:00:00

  • [Immunohistochemical study of the enteric glia in chronic intestinal inflammatory disease].

    abstract::Enteric glial cells, strictly associated with enteric neurons to build up enteric ganglia, belong to the enteric nervous system (ENS), which coordinates many bowel functions. The ENS is spread throughout the gut in myenteric and submucosal plexuses. In our research work, we studied immunohistochemically the ENS in two...

    journal_title:Minerva medica

    pub_type: 杂志文章

    doi:

    authors: Bongioanni P,Castagna M,Morisi M

    更新日期:1996-07-01 00:00:00