Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.

abstract：:William Adams (Miura Anjin) was an English navigator who sailed with a Dutch trading fleet to the far East and landed in Japan in 1600. He became a vassal under the Shogun, Tokugawa Ieyasu, was bestowed with a title, lands and swords, and became the first SAMURAI from England. "Miura" comes from the name of the territ...

journal_title：Scientific reports

authors： Mizuno F,Ishiya K,Matsushita M,Matsushita T,Hampson K,Hayashi M,Tokanai F,Kurosaki K,Ueda S

更新日期：2020-12-10 00:00:00

abstract：:The κ opioid receptor (κOR) is a member of G-protein-coupled receptors, and is considered as a promising drug target for treating neurological diseases. κOR selective 6'-GNTI was proved to be a G-protein biased agonist, whereas 5'-GNTI acts as an antagonist. To investigate the molecular mechanism of how these two liga...

journal_title：Scientific reports

authors： Cheng J,Sun X,Li W,Liu G,Tu Y,Tang Y

更新日期：2016-01-08 00:00:00

abstract：:Recently, it has been reported that human hepatocyte-like cells can be generated from fibroblasts by direct reprogramming technology. However, the conversion efficiency of human induced hepatocyte-like cells (hiHeps) is not high enough. In addition, comparative analysis with the existing models of hepatocytes, such as...

journal_title：Scientific reports

authors： Nakamori D,Akamine H,Takayama K,Sakurai F,Mizuguchi H

更新日期：2017-11-30 00:00:00

abstract：:A highly sensitive bismuth/silver nanoparticles/Nafion-modified screen-printed graphene electrode was fabricated and was utilized for the detection of trace lead (Pb) concentrations in river water samples prior to and after remediation using calamansi (Citrofortunella Microcarpa) rinds in different forms viz., ground ...

journal_title：Scientific reports

authors： Palisoc ST,Vitto RIM,Noel MG,Palisoc KT,Natividad MT

更新日期：2021-01-14 00:00:00

abstract：:Knee osteoarthritis (OA) is the most common musculoskeletal disorder. OA diagnosis is currently conducted by assessing symptoms and evaluating plain radiographs, but this process suffers from subjectivity. In this study, we present a new transparent computer-aided diagnosis method based on the Deep Siamese Convolution...

journal_title：Scientific reports

authors： Tiulpin A,Thevenot J,Rahtu E,Lehenkari P,Saarakkala S

更新日期：2018-01-29 00:00:00

abstract：:Adult-onset vitelliform macular dystrophy (AVMD) is a common and benign macular degeneration which can be caused by BEST1 mutation. Here, we investigated the clinical characteristics associated with a newly identified BEST1 mutation, p.Ile38Ser and confirmed the associated physiological functional defects. The 51-year...

journal_title：Scientific reports

authors： Jun I,Lee JS,Lee JH,Lee CS,Choi SI,Gee HY,Lee MG,Kim EK

更新日期：2017-08-22 00:00:00

abstract：:The health effects of the endocrine disruptor Bisphenol A (BPA) led to its partial replacement with Bisphenol S (BPS) in several products including food containers, toys, and thermal paper receipts. The acute effects of BPS on myocardial contractility are unknown. We perfused mouse hearts from both sexes for 15 min wi...

journal_title：Scientific reports

authors： Ferguson M,Lorenzen-Schmidt I,Pyle WG

更新日期：2019-11-04 00:00:00

abstract：:Strong pinning depends on the pinning force strength and number density of effective defects. Using the hydrostatic pressure method, we demonstrate here that hydrostatic pressure of 1.2 GPa can significantly enhance flux pinning or the critical current density (Jc) of optimally doped Ba0.6K0.4Fe2As2 crystals by a fact...

journal_title：Scientific reports

authors： Shabbir B,Wang X,Ma Y,Dou SX,Yan SS,Mei LM

更新日期：2016-03-17 00:00:00

abstract：:Acute kidney disease (AKD) is a state between acute kidney injury (AKI) and chronic kidney disease (CKD), but the prognosis of AKD is unclear and there are no risk-prediction tools to identify high-risk patients. 2,556 AKI patients were selected from 277,898 inpatients of three affiliated hospitals of Central South Un...

journal_title：Scientific reports

authors： Xiao YQ,Cheng W,Wu X,Yan P,Feng LX,Zhang NY,Li XW,Duan XJ,Wang HS,Peng JC,Liu Q,Zhao F,Deng YH,Yang SK,Feng S,Duan SB

更新日期：2020-09-24 00:00:00

abstract：:Fitness-related costs of evolving insecticide resistance have been reported in a number of insect species, but the interplay between evolutionary adaptation to insecticide pressure and variable environmental conditions has received little attention. We provisioned nymphs from three German cockroach (Blattella germanic...

journal_title：Scientific reports

authors： Jensen K,Ko AE,Schal C,Silverman J

更新日期：2016-06-27 00:00:00

abstract：:Alternatives to antibiotics for improving productivity and maintaining the health of livestock health are urgently needed. The scope of this research was conducted to investigate the effects of two alternatives (Bacillus licheniformis and Saccharomyces cerevisiae) to monensin on growth performance, antioxidant capacit...

journal_title：Scientific reports

authors： Jia P,Cui K,Ma T,Wan F,Wang W,Yang D,Wang Y,Guo B,Zhao L,Diao Q

更新日期：2018-11-12 00:00:00

abstract：:Highly efficient and specific biomolecular recognition requires both affinity and specificity. Previous quantitative descriptions of biomolecular recognition were mostly driven by improving the affinity prediction, but lack of quantification of specificity. We developed a novel method SPA (SPecificity and Affinity) ba...

journal_title：Scientific reports

authors： Yan Z,Wang J

更新日期：2012-01-01 00:00:00

abstract：:Associations between HLA class I alleles and HIV progression in populations exhibiting Amerindian and Caucasian genetic admixture remain understudied. Using univariable and multivariable analyses we evaluated HLA associations with five HIV clinical parameters in 3,213 HIV clade B-infected, ART-naïve individuals from M...

journal_title：Scientific reports

authors： Valenzuela-Ponce H,Alva-Hernández S,Garrido-Rodríguez D,Soto-Nava M,García-Téllez T,Escamilla-Gómez T,García-Morales C,Quiroz-Morales VS,Tapia-Trejo D,Del Arenal-Sánchez S,Prado-Galbarro FJ,Hernández-Juan R,Rodríguez-Aguirre E,

更新日期：2018-04-17 00:00:00

abstract：:Systems with a discrete rotational symmetry [Formula: see text] where [Formula: see text] that also have electromagnetic duality symmetry exhibit zero backscattering. The impact of breaking one of the two symmetries on the emerging backscattering has not yet been systematically studied. Here, we investigate the effect...

journal_title：Scientific reports

authors： Abdelrahman MI,Slivina E,Rockstuhl C,Fernandez-Corbaton I

更新日期：2021-01-18 00:00:00

abstract：:The control of Salmonella from farm to fork is challenging due to the emergence of antimicrobial-resistant isolates and the limited effects of current control methods. Advanced chemical technologies have made accessible a wide range of uncharacterized small molecules (SMs) with encouraging chemical properties for anti...

journal_title：Scientific reports

authors： Deblais L,Helmy YA,Kathayat D,Huang HC,Miller SA,Rajashekara G

更新日期：2018-09-06 00:00:00

abstract：:Feedback information is essential for us to adapt appropriately to the environment. The feedback-related negativity (FRN), a frontocentral negative deflection after the delivery of feedback, has been found to be larger for outcomes that are worse than expected, and it reflects a reward prediction error derived from th...

journal_title：Scientific reports

authors： Gu Y,Hu X,Pan W,Yang C,Wang L,Li Y,Chen A

更新日期：2016-10-03 00:00:00

abstract：:The tissue microenvironment is a major contributor to cellular functions, such as cell adhesion, migration and invasion. A critical physical parameter for determining the effect of the microenvironment on cellular functions is the average pore-size of filamentous scaffolds, such as 3D collagen fiber matrices, which ar...

journal_title：Scientific reports

authors： Fischer T,Hayn A,Mierke CT

更新日期：2019-06-07 00:00:00

abstract：:Although differentiated thyroid carcinoma (DTC) has a good prognosis and survival rate, long-term medication and recurrence monitoring might be needed. The factors that affect postoperative health-related quality of life (HRQoL) in patients with DTC in different regions remain unclear or conflicting. The purpose of th...

journal_title：Scientific reports

authors： Li J,Zhang B,Bai Y,Liu Y,Zhang B,Jin J

更新日期：2020-04-01 00:00:00

abstract：:Commercial Pt/C anodes of direct formic acid fuel cells (DFAFCs) get rapidly poisoned by in-situ generated CO intermediates from formic acid non-faradaic dissociation. We succeeded in increasing the Pt nanoparticles (PtNPs) stability and activity for formic acid oxidation (DFAFCs anodic reaction) by embedding them ins...

journal_title：Scientific reports

authors： El-Nagar GA,Hassan MA,Lauermann I,Roth C

更新日期：2017-12-19 00:00:00

abstract：:We examined whether it is possible to identify individual subjects on the basis of brain anatomical features. For this, we analyzed a dataset comprising 191 subjects who were scanned three times over a period of two years. Based on FreeSurfer routines, we generated three datasets covering 148 anatomical regions (corti...

journal_title：Scientific reports

authors： Valizadeh SA,Liem F,Mérillat S,Hänggi J,Jäncke L

更新日期：2018-04-04 00:00:00

abstract：:An effective analysis method was developed based on a chemometric tool for the simultaneous quantification of five different post-harvest pesticides (2,4-dichlorophenoxyacetic acid (2,4-D), carbendazim, thiabendazole, iprodione, and prochloraz) in fruits and vegetables. In the modified QuEChERS (quick, easy, cheap, ef...

journal_title：Scientific reports

authors： Li M,Dai C,Wang F,Kong Z,He Y,Huang YT,Fan B

更新日期：2017-02-22 00:00:00

abstract：:We report the molecular basis of the largest Tunisian cohort with inherited retinal dystrophies (IRD) reported to date, identify disease-causing pathogenic variants and describe genotype-phenotype correlations. A subset of 26 families from a cohort of 73 families with clinical diagnosis of autosomal recessive IRD (AR-...

journal_title：Scientific reports

authors： Habibi I,Falfoul Y,Turki A,Hassairi A,El Matri K,Chebil A,Schorderet DF,El Matri L

更新日期：2020-07-08 00:00:00

abstract：:We evaluated the effect of separately adding two sources of lanthanum (La), LaCl3 and La(NO3)3 × 6H2O at a concentration of 40 µM each, to the preservative solution of 15 cut tulip flower varieties. Ascorbic acid (AsA; 0.2 g/L) was used as a reference solution, while distilled water was used as control. The variety La...

journal_title：Scientific reports

authors： Gómez-Merino FC,Ramírez-Martínez M,Castillo-González AM,Trejo-Téllez LI

更新日期：2020-03-06 00:00:00

abstract：:Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as rheumatoid arthritis and psoriasis. However, current TNF-α blockers...

journal_title：Scientific reports

authors： Cui X,Chang L,Li Y,Lv Q,Wang F,Lin Y,Li W,Meade JD,Walden JC,Liang P

更新日期：2018-05-09 00:00:00

abstract：:One of the most challenging issues in HIV-associated neurocognitive disorders (HAND) caused by HIV-1 virotoxins and drug abuse is the lack of understanding the underlying mechanisms that are commonly associated with disorders of the blood-brain barrier (BBB), which mainly consists of brain microvascular endothelial ce...

journal_title：Scientific reports

authors： Liu L,Yu J,Li L,Zhang B,Liu L,Wu CH,Jong A,Mao DA,Huang SH

更新日期：2017-01-11 00:00:00

abstract：:Although the cognitive impairment in Alzheimer's disease (AD) is believed to be caused by amyloid-β (Aβ) plaques and neurofibrillary tangles (NFTs), several postmortem studies have reported cognitive normal subjects with AD brain pathology. As the mechanism underlying these discrepancies has not been clarified, we foc...

journal_title：Scientific reports

authors： Kobayashi E,Nakano M,Kubota K,Himuro N,Mizoguchi S,Chikenji T,Otani M,Mizue Y,Nagaishi K,Fujimiya M

更新日期：2018-01-26 00:00:00

abstract：:Chrysopidae (green lacewings) is the second largest family in Neuroptera, and it includes medium-size lacewings largely recognized by the presence of golden-colored eyes, bright green bodies and delicate wings with dense venation patterns. The subfamily Chrysopinae includes 97% of the species diversity in the family a...

journal_title：Scientific reports

authors： Jiang Y,Garzón-Orduña IJ,Winterton SL,Yang F,Liu X

更新日期：2017-08-03 00:00:00

abstract：:The group-IV tin has been hypothesized to possess intriguing electronic properties in an atom-thick hexagonal form. An attractive pathway of producing sizable 2D crystallites of tin is based on deintercalation of bulk compounds with suitable tin frameworks. Here, we have identified a new synthesizable metal distannide...

journal_title：Scientific reports

authors： Shao J,Beaufils C,Kolmogorov AN

更新日期：2016-07-08 00:00:00

abstract：:Mycoplasma pneumoniae infection is conventionally diagnosed using serum antibody testing, microbial culture, and genetic testing. Recently, immunochromatography-based rapid mycoplasma antigen test kits have been developed and commercialised for rapid diagnosis of M. pneumoniae infection. However, as these kits do not ...

journal_title：Scientific reports

authors： Namkoong H,Yamazaki M,Ishizaki M,Endo I,Harada N,Aramaki M,Tanaka Y,Kaburagi S,Ichikawa M,Ohata T,Sakaguchi S,Saito F,Nakao A,Yuki H,Mitamura K

更新日期：2018-01-23 00:00:00

abstract：:Worldwide, Bartonella infections are known to inflict a wide range of mammals and, within rodents alone, more than 20 Bartonella species have been detected. There is, however, a lack of studies on the presence of Bartonella spp. in rodents in the Baltic region. We analysed 580 individuals belonging to eight small rode...

journal_title：Scientific reports

authors： Mardosaitė-Busaitienė D,Radzijevskaja J,Balčiauskas L,Bratchikov M,Jurgelevičius V,Paulauskas A

更新日期：2019-08-26 00:00:00