Abstract:
:In high magnetic fields, two-dimensional electron systems can form a number of phases in which interelectron repulsion plays the central role, since the kinetic energy is frozen out by Landau quantization. These phases include the well-known liquids of the fractional quantum Hall effect, as well as solid phases with broken spatial symmetry and crystalline order. Solids can occur at the low Landau-filling termination of the fractional quantum Hall effect series but also within integer quantum Hall effects. Here we present microwave spectroscopy studies of wide quantum wells that clearly reveal two distinct solid phases, hidden within what in d.c. transport would be the zero diagonal conductivity of an integer quantum-Hall-effect state. Explanation of these solids is not possible with the simple picture of a Wigner solid of ordinary (quasi) electrons or holes.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Hatke AT,Liu Y,Magill BA,Moon BH,Engel LW,Shayegan M,Pfeiffer LN,West KW,Baldwin KWdoi
10.1038/ncomms5154subject
Has Abstractpub_date
2014-06-20 00:00:00pages
4154issn
2041-1723pii
ncomms5154journal_volume
5pub_type
杂志文章abstract::Accurate prediction of an individual's phenotype from their DNA sequence is one of the great promises of genomics and precision medicine. We extend a powerful individual-level data Bayesian multiple regression model (BayesR) to one that utilises summary statistics from genome-wide association studies (GWAS), SBayesR. ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12653-0
更新日期:2019-11-08 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/s41467-019-12107-7
更新日期:2019-09-05 00:00:00
abstract::MicroRNAs (miRNAs) associated with Argonaute proteins (AGOs) regulate gene expression in mammals. miRNA 3' ends are subject to frequent sequence modifications, which have been proposed to affect miRNA stability. However, the underlying mechanism is not well understood. Here, by genetic and biochemical studies as well ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16533-w
更新日期:2020-06-02 00:00:00
abstract::Phagocytosis is responsible for the elimination of particles of widely disparate sizes, from large fungi or effete cells to small bacteria. Though superficially similar, the molecular mechanisms involved differ: engulfment of large targets requires phosphoinositide 3-kinase (PI3K), while that of small ones does not. H...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9623
更新日期:2015-10-14 00:00:00
abstract::The design and assembly of artificial protocell consortia displaying dynamical behaviours and systems-based properties are emerging challenges in bottom-up synthetic biology. Cellular processes such as morphogenesis and differentiation rely in part on reaction-diffusion gradients, and the ability to mimic rudimentary ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11316-4
更新日期:2019-07-25 00:00:00
abstract::In the originally published version of this Article, the affiliation details for Eric E. Schadt and Radoslav Savic incorrectly omitted 'Sema4, a Mount Sinai venture, Stamford, Connecticut, USA'. This has been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-07326-3
更新日期:2018-11-19 00:00:00
abstract::Topologically protected pseudospin transport, analogous to the quantum spin Hall effect, cannot be strictly implemented for photons and in general bosons because of the lack of symmetry-protected pseudospins. Here we show that the required protection can be provided by the real-space topological excitation of an inter...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06520-7
更新日期:2018-09-28 00:00:00
abstract::In addition to acting as a cellular energy source, ATP can also act as a damage-associated molecular pattern in both animals and plants. Stomata are leaf pores that control gas exchange and, therefore, impact critical functions such as photosynthesis, drought tolerance, and also are the preferred entry point for patho...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02340-3
更新日期:2017-12-22 00:00:00
abstract::5-Fluorouracil (5-FU) remains the first-line treatment for colorectal cancer (CRC). Although 5-FU initially de-bulks the tumor mass, recurrence after chemotherapy is the barrier to effective clinical outcomes for CRC patients. Here, we demonstrate that p53 promotes WNT3 transcription, leading to activation of the WNT/...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19173-2
更新日期:2020-10-21 00:00:00
abstract::Studying emerging or neglected pathogens is often challenging due to insufficient information and absence of genetic tools. Dual RNA-seq provides insights into host-pathogen interactions, and is particularly informative for intracellular organisms. Here we apply dual RNA-seq to Orientia tsutsugamushi (Ot), an obligate...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17094-8
更新日期:2020-07-03 00:00:00
abstract::Central insulin is thought to act at the neural interface between metabolic and hedonic drives to eat. Here, using pharmacological fMRI, we show that intranasal insulin (INI) changes the value of food cues through modulation of mesolimbic pathways. Overnight fasted participants rated the palatability of food pictures ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms16052
更新日期:2017-07-18 00:00:00
abstract::Genome replication is highly regulated in time and space, but the rules governing the remodeling of these programs during evolution remain largely unknown. We generated genome-wide replication timing profiles for ten Lachancea yeasts, covering a continuous evolutionary range from closely related to more divergent spec...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-04628-4
更新日期:2018-06-06 00:00:00
abstract::In humans, mutations in the PIEZO2 gene, which encodes for a mechanosensitive ion channel, were found to result in skeletal abnormalities including scoliosis and hip dysplasia. Here, we show in mice that loss of Piezo2 expression in the proprioceptive system recapitulates several human skeletal abnormalities. While lo...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16971-6
更新日期:2020-06-23 00:00:00
abstract::The biological pump transports organic carbon produced by photosynthesis to the meso- and bathypelagic zones, the latter removing carbon from exchanging with the atmosphere over centennial time scales. Organisms living in both zones are supported by a passive flux of particles, and carbon transported to the deep-sea t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19875-7
更新日期:2020-11-27 00:00:00
abstract::Weyl points, as monopoles of Berry curvature in momentum space, have captured much attention recently in various branches of physics. Realizing topological materials that exhibit such nodal points is challenging and indeed, Weyl points have been found experimentally in transition metal arsenide and phosphide and gyroi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13038
更新日期:2016-10-05 00:00:00
abstract::While free electrons in metals respond to ultrafast excitation with refractive index changes on femtosecond time scales, typical relaxation mechanisms occur over several picoseconds, governed by electron-phonon energy exchange rates. Here, we propose tailoring these intrinsic rates by engineering a non-uniform electro...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10840-7
更新日期:2019-07-04 00:00:00
abstract::Symmetry-breaking phase transitions are an example of non-equilibrium processes that require real-time treatment, a major challenge in strongly coupled systems without long-lived quasiparticles. Holographic duality provides such an approach by mapping strongly coupled field theories in D dimensions into weakly coupled...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8406
更新日期:2015-06-23 00:00:00
abstract::Layer-by-layer-stacked chemical vapour deposition (CVD) graphene films find applications as transparent and conductive electrodes in solar cells, organic light-emitting diodes and touch panels. Common to lamellar-type systems with anisotropic electron delocalization, the plane-to-plane (vertical) conductivity in such ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6461
更新日期:2014-11-20 00:00:00
abstract::Mutators represent a successful strategy in rapidly adapting asexual populations, but theory predicts their eventual extinction due to their unsustainably large deleterious load. While antimutator invasions have been documented experimentally, important discrepancies among studies remain currently unexplained. Here we...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11217-6
更新日期:2019-07-15 00:00:00
abstract::Understanding and extracting the full functions of single-molecule characteristics are key factors in the development of future device technologies, as well as in basic research on molecular electronics. Here we report a new methodology for realizing a three-dimensional (3D) dynamic probe of single-molecule conductanc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9465
更新日期:2015-10-06 00:00:00
abstract::The xeroderma pigmentosum C (XPC) complex initiates nucleotide excision repair by recognizing DNA lesions before recruiting downstream factors. How XPC detects structurally diverse lesions embedded within normal DNA is unknown. Here we present a crystal structure that captures the yeast XPC orthologue (Rad4) on a sing...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6849
更新日期:2015-01-06 00:00:00
abstract::Flexible organic memory devices are one of the integral components for future flexible organic electronics. However, high-density all-organic memory cell arrays on malleable substrates without cross-talk have not been demonstrated because of difficulties in their fabrication and relatively poor performances to date. H...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3707
更新日期:2013-01-01 00:00:00
abstract::Clustered regularly-interspaced palindromic repeats (CRISPR)-based genetic screens using single-guide-RNA (sgRNA) libraries have proven powerful to identify genetic regulators. Applying CRISPR screens to interrogate functional elements in noncoding regions requires generating sgRNA libraries that are densely covering,...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11178
更新日期:2016-03-30 00:00:00
abstract::The isolation of the two-dimensional semiconductor molybdenum disulphide introduced a new optically active material possessing a band gap that can be facilely tuned via elastic strain. As an atomically thin membrane with exceptional strength, monolayer molybdenum disulphide subjected to biaxial strain can embed wide b...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8381
更新日期:2015-06-19 00:00:00
abstract::Ufuk Günesdogan was incorrectly associated with Center for Genetic Analysis of Behaviour, National Institute for Physiological Sciences, 5-1 Higashiyama Myodaiji, Okazaki, Aichi 444-8787, Japan and Toshihiro Kobayashi was incorrectly associated with Department of Developmental Biology, University of Göttingen, Götting...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-07765-y
更新日期:2018-12-11 00:00:00
abstract::Excessive nitrogen runoff leads to degraded water quality, harming human and ecosystem health. We examine the impact of changes in land use and land management for six combinations of socioeconomic pathways and climate outcomes, and find that societal choices will substantially impact riverine total nitrogen loading (...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08884-w
更新日期:2019-02-26 00:00:00
abstract::The construction of enzyme-inspired artificial catalysts with enzyme-like active sites and microenvironment remains a great challenge. Herein, we report a single-atomic-site Co catalyst supported by carbon doped boron nitride (BCN) with locally polarized B-N bonds (Co SAs/BCN) to simulate the reductive dehalogenases. ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20619-w
更新日期:2021-01-12 00:00:00
abstract::Building a population-specific catalogue of single nucleotide variants (SNVs), indels and structural variants (SVs) with frequencies, termed a national pan-genome, is critical for further advancing clinical and public health genetics in large cohorts. Here we report a Danish pan-genome obtained from sequencing 10 trio...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6969
更新日期:2015-01-19 00:00:00
abstract::Overexpression of a drug's molecular target often increases drug resistance, offering a pathway for adaptive evolution and a tool for target identification. It is unclear though why this phenomenon applies to some drugs but not others. Here we gradually overexpressed antibiotic targets in Escherichia coli and found th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5296
更新日期:2014-07-01 00:00:00
abstract::Extracellular matrix (ECM) proteins secreted by blood-brain barrier (BBB) endothelial cells (ECs) are implicated in cell trafficking. We discovered that the expression of ECM epidermal growth factor-like protein 7 (EGFL7) is increased in the CNS vasculature of patients with multiple sclerosis (MS), and in mice with ex...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03186-z
更新日期:2018-02-26 00:00:00