Thinking in circuits: toward neurobiological explanation in cognitive neuroscience.

Abstract:

:Cognitive theory has decomposed human mental abilities into cognitive (sub) systems, and cognitive neuroscience succeeded in disclosing a host of relationships between cognitive systems and specific structures of the human brain. However, an explanation of why specific functions are located in specific brain loci had still been missing, along with a neurobiological model that makes concrete the neuronal circuits that carry thoughts and meaning. Brain theory, in particular the Hebb-inspired neurocybernetic proposals by Braitenberg, now offers an avenue toward explaining brain-mind relationships and to spell out cognition in terms of neuron circuits in a neuromechanistic sense. Central to this endeavor is the theoretical construct of an elementary functional neuronal unit above the level of individual neurons and below that of whole brain areas and systems: the distributed neuronal assembly (DNA) or thought circuit (TC). It is shown that DNA/TC theory of cognition offers an integrated explanatory perspective on brain mechanisms of perception, action, language, attention, memory, decision and conceptual thought. We argue that DNAs carry all of these functions and that their inner structure (e.g., core and halo subcomponents), and their functional activation dynamics (e.g., ignition and reverberation processes) answer crucial localist questions, such as why memory and decisions draw on prefrontal areas although memory formation is normally driven by information in the senses and in the motor system. We suggest that the ability of building DNAs/TCs spread out over different cortical areas is the key mechanism for a range of specifically human sensorimotor, linguistic and conceptual capacities and that the cell assembly mechanism of overlap reduction is crucial for differentiating a vocabulary of actions, symbols and concepts.

journal_name

Biol Cybern

journal_title

Biological cybernetics

authors

Pulvermüller F,Garagnani M,Wennekers T

doi

10.1007/s00422-014-0603-9

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

573-93

issue

5

eissn

0340-1200

issn

1432-0770

journal_volume

108

pub_type

杂志文章,评审
  • Properties of basis functions generated by shift invariant sparse representations of natural images.

    abstract::The idea that a sparse representation is the computational principle of visual systems has been supported by Olshausen and Field [Nature (1996) 381: 607-609] and many other studies. On the other hand neurons in the inferotemporal cortex respond to moderately complex features called icon alphabets, and such neurons res...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220000149

    authors: Hashimoto W,Kurata K

    更新日期:2000-08-01 00:00:00

  • On the description of neuronal output properties using spike train data.

    abstract::Neuronal output properties for input stimuli that evoke a deterministic response can be efficiently described by the interspike-interval function (Awiszus 1988a). It is shown in this paper that there are stimuli for which both the Hodgkin-Huxley (HH-) model of an action potential encoding membrane (Hodgkin and Huxley ...

    journal_title:Biological cybernetics

    pub_type: 杂志文章,评审

    doi:10.1007/BF00204770

    authors: Awiszus F

    更新日期:1989-01-01 00:00:00

  • Simulation of nonstationary EEG.

    abstract::In this paper we present a systematic method for generating simulations of nonstationary EEG. Such simulations are needed, for example, in the evaluation of tracking algorithms. First a state evolution process is simulated. The states are initially represented as segments of stationary autoregressive processes which a...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220050348

    authors: Kaipio JP,Karjalainen PA

    更新日期:1997-05-01 00:00:00

  • Comparing internal models of the dynamics of the visual environment.

    abstract::It is well known that the human postural control system responds to motion of the visual scene, but the implicit assumptions it makes about the visual environment and what quantities, if any, it estimates about the visual environment are unknown. This study compares the behavior of four models of the human postural co...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-004-0535-x

    authors: Carver S,Kiemel T,van der Kooij H,Jeka JJ

    更新日期:2005-03-01 00:00:00

  • Palisade endings and proprioception in extraocular muscles: a comparison with skeletal muscles.

    abstract::This article describes current views on motor and sensory control of extraocular muscles (EOMs) based on anatomical data. The special morphology of EOMs, including their motor innervation, is described in comparison to classical skeletal limb and trunk muscles. The presence of proprioceptive organs is reviewed with em...

    journal_title:Biological cybernetics

    pub_type: 杂志文章,评审

    doi:10.1007/s00422-012-0519-1

    authors: Lienbacher K,Horn AK

    更新日期:2012-12-01 00:00:00

  • A posteriori time-varying filtering of averaged evoked potentials. II. Mathematical and computational aspects.

    abstract::The problem of estimating an unknown transient signal, given an ensemble of waveforms, in which this signal appears as a nonrandom component in the presence of additive noise is considered. This problem is solved by generalizing the method of "a posteriori 'Wiener' filtering". In the new method, the ensemble average i...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00340323

    authors: de Weerd JP,Kap JI

    更新日期:1981-01-01 00:00:00

  • Slow changes and Wiener analysis of nonlinear summation in contractions in cat muscles.

    abstract::With regular trains of stimuli at a high frequency, the contribution of each stimulus to the force generated over time declines from the second to about the tenth stimulus, but then begins to increase again. This late increase is referred to as tetanic potentiation in analogy with the post-tetanic potentiation of the ...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00340074

    authors: Parmiggiani F,Stein RB,Rolf R

    更新日期:1982-01-01 00:00:00

  • The relationship between absolute disparity and ocular vergence.

    abstract::The relationship between disparity and ocular vergence was investigated under closed-loop as well as under open-loop viewing conditions. First we examined whether vergence responded similarly to disparity presented under open-loop and closed-loop conditions. Similar response were observed in both conditions. The direc...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00224855

    authors: Pobuda M,Erkelens CJ

    更新日期:1993-01-01 00:00:00

  • A neural network study of precollicular saccadic averaging.

    abstract::Saccadic averaging is the phenomenon that two simultaneously presented retinal inputs result in a saccade with an endpoint located on an intermediate position between the two stimuli. Recordings from neurons in the deeper layers of the superior colliculus have revealed neural correlates of saccade averaging, indicatin...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220050450

    authors: Krommenhoek KP,Wiegerinck WA

    更新日期:1998-06-01 00:00:00

  • A model for light adaptation: producing Weber's law with bleaching-type kinetics.

    abstract::An "adaptation model" having two stages is introduced and its mathematical properties are examined. The two stages are the "adaptive process" (parameter Kb), which has bleaching-type kinetics, and the "response function" (parameters Kr and n), which incorporates response saturation. In order to study the increment thr...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00361040

    authors: Dawis SM

    更新日期:1978-09-28 00:00:00

  • Information-theoretic analysis of de-efferented single muscle spindles.

    abstract::The information transmission properties of single, de-efferented primary muscle-spindle afferents from the hind limb of the cat were investigated. The gastrocnemius medialis muscle was stretched randomly while recording spike trains from several muscle-spindle afferents in the dorsal root. Two classes of input stimuli...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-002-0341-2

    authors: Tock Y,Ljubisavljevic M,Thunberg J,Windhorst U,Inbar GF,Johansson H

    更新日期:2002-10-01 00:00:00

  • Dynamical estimation of neuron and network properties III: network analysis using neuron spike times.

    abstract::Estimating the behavior of a network of neurons requires accurate models of the individual neurons along with accurate characterizations of the connections among them. Whereas for a single cell, measurements of the intracellular voltage are technically feasible and sufficient to characterize a useful model of its beha...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-014-0601-y

    authors: Knowlton C,Meliza CD,Margoliash D,Abarbanel HD

    更新日期:2014-06-01 00:00:00

  • On the respresentation of multi-input systems: computational properties of polynomial algorithms.

    abstract::This paper introduces a theoretical frame-work for characterizing and classifying simple parallel algorithms and systems with many inputs, for example an array of photoreceptors. The polynomial representation (Taylor series development) of a large class of operators is introduced and its range of validity discussed. T...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00355455

    authors: Poggio T,Reichardt W

    更新日期:1980-01-01 00:00:00

  • Conductance-based refractory density approach: comparison with experimental data and generalization to lognormal distribution of input current.

    abstract::The conductance-based refractory density (CBRD) approach is an efficient tool for modeling interacting neuronal populations. The model describes the firing activity of a statistical ensemble of uncoupled Hodgkin-Huxley-like neurons, each receiving individual Gaussian noise and a common time-varying deterministic input...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-017-0727-9

    authors: Chizhov AV

    更新日期:2017-12-01 00:00:00

  • Synchronizing human movement with an external clock source.

    abstract::Temporal information processing was studied in humans attempting to tap a key in synchrony with a metronome whose base period was subjected to subliminal random changes. Statistical measures of the sequential timing of metronome and key-tap events were compared with similar time series generated by computer-simulated ...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00319511

    authors: Hary D,Moore GP

    更新日期:1987-01-01 00:00:00

  • Human stick balancing: an intermittent control explanation.

    abstract::There are two issues in balancing a stick pivoting on a finger tip (or mechanically on a moving cart): maintaining the stick angle near to vertical and maintaining the horizontal position within the bounds of reach or cart track. The (linearised) dynamics of the angle are second order (although driven by pivot acceler...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-013-0564-4

    authors: Gawthrop P,Lee KY,Halaki M,O'Dwyer N

    更新日期:2013-12-01 00:00:00

  • Dynamic updating of distributed neural representations using forward models.

    abstract::In this paper, we present a continuous attractor network model that we hypothesize will give some suggestion of the mechanisms underlying several neural processes such as velocity tuning to visual stimulus, sensory discrimination, sensorimotor transformations, motor control, motor imagery, and imitation. All of these ...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-006-0131-3

    authors: Sauser EL,Billard AG

    更新日期:2006-12-01 00:00:00

  • Multifrequency behavioral patterns and the phase attractive circle map.

    abstract::With relative phase as a collective variable or order parameter, phase attractive dynamics can capture the temporally coherent behavior of a large number of different experimental systems. We present results from multifrequency coordination experiments in humans showing: a) that phase attraction persists especially fo...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00202613

    authors: deGuzman GC,Kelso JA

    更新日期:1991-01-01 00:00:00

  • Revealing non-analytic kinematic shifts in smooth goal-directed behaviour.

    abstract::How do biological agents plan and organise a smooth accurate path to shift from one smooth mode of behaviour to another as part of graceful movement that is both plastic and controlled? This paper addresses the question in conducting a novel shape analysis of approach and adjustment phases in rapid voluntary target ai...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-011-0449-3

    authors: Weir MK,Wale AP

    更新日期:2011-08-01 00:00:00

  • From lamprey to salamander: an exploratory modeling study on the architecture of the spinal locomotor networks in the salamander.

    abstract::The evolutionary transition from water to land required new locomotor modes and corresponding adjustments of the spinal "central pattern generators" for locomotion. Salamanders resemble the first terrestrial tetrapods and represent a key animal for the study of these changes. Based on recent physiological data from sa...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-012-0538-y

    authors: Bicanski A,Ryczko D,Cabelguen JM,Ijspeert AJ

    更新日期:2013-10-01 00:00:00

  • Study of neuronal gain in a conductance-based leaky integrate-and-fire neuron model with balanced excitatory and inhibitory synaptic input.

    abstract::Neurons receive a continual stream of excitatory and inhibitory synaptic inputs. A conductance-based neuron model is used to investigate how the balanced component of this input modulates the amplitude of neuronal responses. The output spiking rate is well described by a formula involving three parameters: the mean mu...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-003-0408-8

    authors: Burkitt AN,Meffin H,Grayden DB

    更新日期:2003-08-01 00:00:00

  • Saccade control in a simulated robot camera-head system: neural net architectures for efficient learning of inverse kinematics.

    abstract::The high speed of saccades means that they cannot be guided by visual feedback, so that any saccadic control system must know in advance the correct output signals to fixate a particular retinal position. To investigate neural-net architectures for learning this inverse-kinematics problem we simulated a 4 deg-of-freed...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00196450

    authors: Dean P,Mayhew JE,Thacker N,Langdon PM

    更新日期:1991-01-01 00:00:00

  • Human visual navigation in the presence of 3-D rotations.

    abstract::We report on the ability of human observers in judging their direction of translation from sparse, moving random dot patterns for varying extents of 3--D rotation. The observers have to discriminate possible axes of translation with angular separations of 2.5 deg or 5 deg. The field of view is either 20 X 20 deg or 10...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00449594

    authors: Rieger JH,Toet L

    更新日期:1985-01-01 00:00:00

  • Pattern-recognition by an artificial network derived from biologic neuronal systems.

    abstract::A novel artificial neural network, derived from neurobiological observations, is described and examples of its performance are presented. This DYnamically STable Associative Learning (DYSTAL) network associatively learns both correlations and anticorrelations, and can be configured to classify or restore patterns with...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00197642

    authors: Alkon DL,Blackwell KT,Barbour GS,Rigler AK,Vogl TP

    更新日期:1990-01-01 00:00:00

  • Estimation of dynamic joint torques and trajectory formation from surface electromyography signals using a neural network model.

    abstract::In this study, human arm movement was reconstructed from electromyography (EMG) signals using a forward dynamics model acquired by an artificial neural network within a modular architecture. Dynamic joint torques at the elbow and shoulder were estimated for movements in the horizontal plane from the surface EMG signal...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00199465

    authors: Koike Y,Kawato M

    更新日期:1995-09-01 00:00:00

  • A control model of human tongue movements in speech.

    abstract::Tongue movements during speech production have been investigated by means of a simple yet realistic biomechanical model, based on a finite elements modeling of soft tissues, in the framework of the equilibrium point hypothesis (lambda-model) of motor control. In particular, the model has been applied to the estimation...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220050362

    authors: Sanguineti V,Laboissière R,Payan Y

    更新日期:1997-07-01 00:00:00

  • Numerical fourier transform spectroscopy of EMG half-waves: fragmentary-decomposition-based approach to nonstationary signal analysis.

    abstract::A nonstationary signal analysis technique is introduced, which regards an oscillatory physiological signal as a sum of its fragments, presented in the form of a fragmentary decomposition (FD). The virtue of FD is that it is free of the necessity to choose a priori the basis functions intended for signal analysis or sy...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220050575

    authors: Melkonian D,Blumenthal T,Gordon E

    更新日期:1999-11-01 00:00:00

  • Animals and ICE: meaning, origin, and diversity.

    abstract::ICE stands for internally coupled ears. More than half of the terrestrial vertebrates, such as frogs, lizards, and birds, as well as many insects, are equipped with ICE that utilize an air-filled cavity connecting the two eardrums. Its effect is pronounced and twofold. On the basis of a solid experimental and mathemat...

    journal_title:Biological cybernetics

    pub_type: 社论

    doi:10.1007/s00422-016-0702-x

    authors: van Hemmen JL,Christensen-Dalsgaard J,Carr CE,Narins PM

    更新日期:2016-10-01 00:00:00

  • A test for constant natural frequencies in electrocortical activity under lateral hypothalamic control.

    abstract::An initial test for a theory of lateral hypothalamic regulation of electrocortical activity is undertaken. The theory supposes lateral hypothalamic input directly or indirectly damps telencephalic resonances involving linear wave phenomena, enabling this pathway to act as parametric control of information processing i...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00337154

    authors: Wright JJ,Kydd RR

    更新日期:1984-01-01 00:00:00

  • Optimal association with partly missing key vectors.

    abstract::A new association scheme which can still recall appropriate data when some key elements are missing (blank) is presented. The traditional associative memory models are designed to deal with complete (memorized) keys, but in the real world, key elements are often missing due to error, equipment failure, observation dif...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00317975

    authors: Murakami K,Aibara T

    更新日期:1982-01-01 00:00:00