Abstract:
AIM:We aimed to investigate the role of adiponectin in acute rheumatic fever by evaluating correlations with cytokines and acute-phase reactants. METHODS:Patients were divided into three groups by clinical findings. Group 1 included 8 patients with only chorea, Group 2 included 13 patients with arthritis and carditis, and Group 3 included 12 patients with only carditis. A total of 54 age- and gender-matched children were enrolled in the control group. Blood samples were drawn for analysing acute-phase reactants, adiponectin, tumour necrosis factor-α, interleukin-6, and interleukin-8 levels at baseline on Days 2, 5, 10, and 15, and at 8 weeks. RESULTS:There was no statistically significant difference between baseline age, gender, body mass index, serum triglyceride, total cholesterol, and low-density lipoprotein levels of the study and control groups (p>0.05). No correlation was found between baseline plasma adiponectin levels, age, body mass index, follicle-stimulating hormone, luteinising hormone, oestradiol, total testosterone, and blood lipid levels of the study and control groups (p>0.05). We found that adiponectin and interleukin-6 levels increased, tumour necrosis factor-α levels decreased, and interleukin-8 levels remained unchanged in acute rheumatic fever, which is an inflammatory disease. Moreover, adiponectin level was higher and tumour necrosis factor-α level was lower in the improvement period in comparison with the acute period, particularly in the carditis group. CONCLUSION:It was considered that, increasing throughout the treatment period, adiponectin may have anti-inflammatory effects in acute rheumatic fever. In addition, adiponectin levels are associated with a decline in inflammatory mediators in rheumatic fever.
journal_name
Cardiol Youngjournal_title
Cardiology in the youngauthors
Ozgen H,Ucar B,Yildirim A,Colak O,Bal C,Kilic Zdoi
10.1017/S1047951114001012subject
Has Abstractpub_date
2015-06-01 00:00:00pages
879-92issue
5eissn
1047-9511issn
1467-1107pii
S1047951114001012journal_volume
25pub_type
杂志文章abstract::Isolated aortic regurgitation and myocardial infarction are a rare congenital defect among neonatal patients. We present a case of a neonate with an unusual aortic valve morphology causing both regurgitation and obstruction of the left coronary artery ostium. Despite both non-invasive and invasive imaging modalities, ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120001377
更新日期:2020-07-01 00:00:00
abstract:UNLABELLED:Aims This is the first autopsy study in the United Kingdom to analyse the demographic and pathological characteristics of atheroma associated with sudden cardiac death in young people. METHODS:An observational retrospective study of referred cases of sudden cardiac death in the young (⩽35 years) associated ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115001286
更新日期:2016-04-01 00:00:00
abstract::Untreated congenital long QT syndrome may result in potentially lethal ventricular tachycardia. In the most common type, risk of such an event has been linked to exercise. This originally resulted in very restrictive guidelines for sports participation in affected individuals. Although the complex interactions of a sp...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951116002225
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to detect structural and functional changes in the left and right ventricles in obese Egyptian adolescents. Methods and results Anthropometric and echocardiographic parameters, including tissue Doppler imaging, were obtained from 70 obese adolescents with average body mass inde...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001910
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Right heart function is an important predictor of morbidity and mortality in pulmonary arterial hypertension and many CHD. We investigated whether treatment with the prostacyclin analogue treprostinil could prevent pressure overload-induced right ventricular hypertrophy and failure. METHODS:Male Wistar rats...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116000160
更新日期:2017-01-01 00:00:00
abstract::A 10-month-old infant with severe tricuspid valve disease due to staphylococcal bacterial endocarditis, underwent surgical replacement of the valve. The new valve was fashioned using an autologous pericardial patch. Over 3 years of follow-up, the new valve has functioned satisfactorily, with moderately elevated right ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001903
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To categorise records according to primary cardiac diagnosis in the United Kingdom Central Cardiac Audit Database in order to add this information to a risk adjustment model for paediatric cardiac surgery. DESIGN:Codes from the International Paediatric Congenital Cardiac Code were mapped to recognisable prim...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951112001369
更新日期:2013-08-01 00:00:00
abstract::Arterial switch surgery for d-transposition of great arteries is usually performed in the first 2 weeks of life before the left ventricle regresses. The arterial switch surgery that helps achieve anatomic and physiologic correction of this condition has better long-term outcomes than other surgical approaches. The pro...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001004
更新日期:2012-02-01 00:00:00
abstract::An interarterial course of anomalous left main coronary artery originating from the right aortic coronary sinus of valsalva is a rare condition among anomalous aortic origin of the coronary artery. Various surgical options are available. We performed an alternative procedure, that is, mobilisation of the pulmonic root...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111002113
更新日期:2012-10-01 00:00:00
abstract::Catecholaminergic polymorphic ventricular tachycardia is a rare life-threatening arrhythmogenic disorder. An association with paroxysmal atrial fibrillation and other atrial arrhythmias has been described, but in all published cases the initial manifestation of the disease was ventricular arrhythmia. This is the first...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113001091
更新日期:2014-08-01 00:00:00
abstract::Sialidosis, a rare autosomal recessive disorder, is caused by a deficiency of NEU1 encoded enzyme alpha-N-acetyl neuraminidase. We report a premature male with neonatal-onset type II sialidosis which was associated with left ventricular dysfunction. The clinical presentation and subsequent progression which culminated...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120004953
更新日期:2021-01-28 00:00:00
abstract::Improvements in diagnosis and surgical technique for correction have led to an increasing number of women with congenital heart disease reaching the child-bearing age. Pregnancy places considerable strain on the heart and circulation and necessitates marked cardiorespiratory adaptation. Today, with the exception of th...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/s1047951100007496
更新日期:1999-01-01 00:00:00
abstract::ABSTRACTPatent ductus arteriosus is among the most common congenital heart diseases. With the increasing use of transcatheter closure procedures, the incidence of complications related to the procedure has increased. Embolization of the ductus closure device to the pulmonary artery is a very rare complication. Since t...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119000921
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Neonates undergoing heart surgery for CHD are at risk for postoperative gastrointestinal complications and aspiration events. There are limited data regarding the prevalence of aspiration after neonatal cardiothoracic surgery; thus, the effects of aspiration events on this patient population are not well und...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795111600278X
更新日期:2017-09-01 00:00:00
abstract::In Respiratory Syncytial Virus infection, the early identification of infants at risk for severe disease in order to potentially decrease morbidity could be considered a major goal. Current guidelines recommend only clinical observation for this purpose in infants without known comorbidities. However, recent evidence ...
journal_title:Cardiology in the young
pub_type: 信件
doi:10.1017/S1047951119002348
更新日期:2019-11-01 00:00:00
abstract::VACTERL association and Scimitar syndrome are rare congenital diseases. In this study, we report on a neonate with prenatal suspicion of VACTERL association and small left-sided cardiac structures, which, only on postnatal angiography, could be revealed to be part of a Scimitar syndrome. As this is the second reported...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114000924
更新日期:2015-03-01 00:00:00
abstract::Introduction Neurodevelopmental abnormalities are common in children with CHD and are the highest-priority concerns for parents and professionals following cardiac surgery in childhood. There is no additional routine monitoring of development for children with CHD in the United Kingdom; hence, neurodevelopmental conce...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117002918
更新日期:2018-04-01 00:00:00
abstract::Congenital anomalies of the coronary arteries are present in 0.2-1.4% of the general population. These anomalies represent one of the most confusing issues in the field of cardiology and challenges for interventional cardiologists and cardiac surgeons if the anomalies are unrecognised. Double right coronary artery is ...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951113000176
更新日期:2014-02-01 00:00:00
abstract::Percutaneous treatment of aortic coarctation is a widely used option. Covered stents have increased the profile of efficacy and safety of this procedure. Here we report on a 32-year-old woman with significant aortic recoarctation associated with aortic wall aneurysm and close proximity of both lesions to the origin of...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114001061
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Infants undergoing stage 1 palliation for hypoplastic left heart syndrome may have post-operative feeding difficulties. Although the cause of feeding difficulties in these patients is multi-factorial, residual arch obstruction may affect gut perfusion, contributing to feeding intolerance. We hypothesised t...
journal_title:Cardiology in the young
pub_type: 杂志文章,多中心研究
doi:10.1017/S1047951120000177
更新日期:2020-03-01 00:00:00
abstract::Most patients with the Mustard procedure are now adults. To date, however, there have been few reports on resting and exercise hemodynamics in a large population of adults with this circulation. The aim of this study is to describe such parameters in one of the largest and oldest populations of adults with the Mustard...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s104795110100052x
更新日期:2001-07-01 00:00:00
abstract::Myocardial ischaemia and infarction in pulmonary atresia and intact ventricular septum with right ventricular-dependent coronary circulation is a well-established complication. We report an interesting case of an acquired aneurysm in the ventricular septum in a patient who underwent staged palliation. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001120
更新日期:2012-04-01 00:00:00
abstract::Fibrates are peroxisome proliferator-activated receptor-α agonists and are clinically used for treatment of dyslipidemia and hypertriglyceridemia. Fenofibrate is reported as a cardioprotective agent in various models of cardiac dysfunction; however, limited literature is available regarding the role of gemfibrozil as ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S104795111400081X
更新日期:2015-04-01 00:00:00
abstract::The aims of this study were to assess the development of heart failure in patients with congenitally corrected transposition of the great arteries in a medium-term follow-up, to identify the impact of tricuspid regurgitation on the development of heart failure, and to determine the most reliable marker for its identif...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114002479
更新日期:2015-10-01 00:00:00
abstract::Chest pain in adolescents is rarely associated with cardiac disease. Adolescents with medically unexplained chest pain usually have high levels of anxiety and depression. Psychological stress may trigger non-cardiac chest pain. This study evaluated risk factors that particularly characterise adolescence, such as major...
journal_title:Cardiology in the young
pub_type: 杂志文章,多中心研究
doi:10.1017/S1047951116002109
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:Arrhythmias are common in patients admitted to the paediatric intensive care unit. We sought to identify the rates of occurrence and types of arrhythmias, and determine whether an arrhythmia was associated with illness severity and paediatric intensive care unit length of stay. DESIGN:This is a prospective, ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114002339
更新日期:2015-10-01 00:00:00
abstract::Cognitive, functional, educational achievement and behavioural measures were employed to assess neurobehavioral status in 57 of 60 participants who were initially enrolled in the Baltimore-Washington Infant Study, and who survived surgical correction of complete transposition (concordant atrioventricular and discordan...
journal_title:Cardiology in the young
pub_type: 杂志文章,多中心研究
doi:10.1017/s1047951100006867
更新日期:1998-07-01 00:00:00
abstract::Conotruncal heart defects are considered to be one of the most common types of birth defect worldwide. Genetic disturbances in folate metabolism such as Thymidylate synthase may increase risk for conotruncal heart defects. We evaluated two common Thymidylate synthase polymorphisms, including the 28 bp tandem repeat in...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951118002184
更新日期:2018-12-21 00:00:00
abstract:OBJECTIVE:To evaluate heart rate variability by Holter monitoring in type 1 diabetic children compared with a healthy control group and determine the factors modifying heart rate variability. METHODS:This was designed as a prospective study comparing 28 patients, diagnosed with type 1 diabetes and under follow-up, wit...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113001224
更新日期:2014-10-01 00:00:00
abstract::Several surgical approaches for completion of a total cavopulmonary connection have been established for patients with anomalies of systemic venous connection in association with a functionally univentricular heart. We report an alternative technique designed to address the problem of widely separated inferior systemi...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116001311
更新日期:2017-03-01 00:00:00