Effect of occlusal rehabilitation on spatial memory and hippocampal neurons after long-term loss of molars in rats.

Abstract:

:Experimental loss of occlusal support caused by the extraction or grinding of molar teeth has been reported to foment the impairment of learning and memory in laboratory animals. The purpose of this study was to examine the effect of occlusal reconstruction after long-term loss of molars on spatial memory by using 8-arm radial maze and by assessing histopathological changes of neuron density in the hippocampus. Experimental dentures were inserted into the oral cavities of molarless rats to recover the occlusal support. Age-matched groups of control, molarless and denture-wearing rats were trained to perform the maze tasks. The difference of the error incidence in the maze task was evaluated between three groups. The difference of neuron density between three groups was also evaluated at the end of the maze task. Serum corticosterone levels were also measured to estimate the chronic stress, which could be caused by extraction, insertion of the experimental denture or any experimental procedure. The error incidence in the denture-wearing group was significantly higher than that of the control group, but significantly lower than that of the molarless group. Significant differences of neuron density were observed between three groups in each of the hippocampal CA1, CA3 and DG subfields. No significant difference of the serum corticosterone levels between three groups could be observed. From the results of this study, it was suggested that the recovery of occlusal support would bring amelioration of cognitive impairment concomitant with long period loss of molars in rats.

journal_name

J Oral Rehabil

authors

Sakamoto S,Hara T,Kurozumi A,Oka M,Kuroda-Ishimine C,Araki D,Iida S,Minagi S

doi

10.1111/joor.12198

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

715-22

issue

10

eissn

0305-182X

issn

1365-2842

journal_volume

41

pub_type

杂志文章
  • Jaw movements in patients with a history of pain: an exploratory study.

    abstract::The aims were to determine whether individuals with a past history of pain exhibit (i) altered jaw movement (e.g. reduced amplitude, increased jaw movement variability) in comparison with matched asymptomatic controls, and (ii) correlations between psychological measures (e.g. catastrophising) and altered jaw movement...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/joor.12220

    authors: Bhaskaracharya M,Memon SM,Whittle T,Murray GM

    更新日期:2015-01-01 00:00:00

  • In vitro cytotoxicity of six dentin bonding agents.

    abstract::The cytotoxicity of six dentin bonding agents (Syntac, Solobond, Bond 1, Scotchbond 1, Heliobond and F-2000) was tested against an established cell line, L929. Under aseptic conditions 3, 5 and 10 microL dentin bonding agents were placed in the centre of Petri dishes. Each dish was covered with a 5-mL suspension of fi...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1046/j.1365-2842.2001.00769.x

    authors: Koliniotou-Koubia E,Dionysopoulos P,Koulaouzidou EA,Kortsaris AH,Papadogiannis Y

    更新日期:2001-10-01 00:00:00

  • Monitoring of the discrimination threshold for interocclusal thicknesses in rehabilitated edentulous patients.

    abstract::Thirty-seven white Caucasian subjects with unsatisfactory dentures were tested for interocclusal thickness discrimination threshold. New dentures were prepared and the test was repeated on days 1, 4 and 90 (from delivery). Eight patients whose situation was still unsatisfactory were given osseointegrated implant ancho...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1994.tb01137.x

    authors: Preti G,Gassino G,Lombardi M,Mazzone P

    更新日期:1994-03-01 00:00:00

  • Osseointegration of anodized titanium implants under different current voltages: a rabbit study.

    abstract::The oxide layer that covers a titanium surface is extremely stable and appears to have excellent biocompatibility, which can result in successful osseointegration. The aim of this study was to analyse the characteristics of an oxide layer formed by anodic oxidation (anodization), and to evaluate the extent of bone hea...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.2006.01688.x

    authors: Park KH,Heo SJ,Koak JY,Kim SK,Lee JB,Kim SH,Lim YJ

    更新日期:2007-07-01 00:00:00

  • Leached components from dental composites in oral simulating fluids and the resultant composite strengths.

    abstract::The aim of this study was to analyse the leached moieties of dental composites after storage in ethanol and organic acids of plaque and further evaluate the resultant effect on the diametral tensile strength (DTS) of the composites. Three commercial composites were used: Bis-GMA-based Z100, Bis-GMA/UDMA-based Heliomol...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1046/j.1365-2842.1998.00284.x

    authors: Lee SY,Huang HM,Lin CY,Shih YH

    更新日期:1998-08-01 00:00:00

  • The effectiveness of dentine adhesives as demonstrated by dye penetration and SEM investigations.

    abstract::A previous investigation identified three types of cuspal movement that occur as a result of polymerization shrinkage when extracted molar teeth are filled with a microfine or hybrid composite used in conjunction with a dentine adhesive. That investigation was extended further by dye penetration and SEM studies of the...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1990.tb00019.x

    authors: Hegarty SM,Pearson GJ

    更新日期:1990-07-01 00:00:00

  • Asymmetry of masticatory muscle activity during intercuspal maximal clenching in healthy subjects and subjects with stomatognathic dysfunction syndrome.

    abstract::The present study investigated the asymmetry of masticatory muscle activity during maximal intercuspal clenching in healthy subjects and subjects with stomatognathic dysfunction syndrome. Stomatognathic dysfunction syndrome, unilateral mastication and the asymmetry of masticatory muscle activity appear to be related t...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1995.tb01069.x

    authors: Abekura H,Kotani H,Tokuyama H,Hamada T

    更新日期:1995-09-01 00:00:00

  • Clinico-pathological study on denture stomatitis.

    abstract::The clinical and pathological study was performed in order to determine the histopathological and cytoimmunological characteristics of denture stomatitis. All specimens were biopsy materials from seventeen patients with denture stomatitis. Normal palatal mucosae from ten patients served as the control. In addition to ...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1987.tb00747.x

    authors: Morimoto K,Kihara A,Suetsugu T

    更新日期:1987-11-01 00:00:00

  • Difference in dental arch size between obese and non-obese patients with obstructive sleep apnoea.

    abstract::A large tongue is recognised as a factor that increases the collapsibility of the upper airway in obstructive sleep apnoea (OSA) patients. We hypothesised that the propensity to develop severe OSA could be minimised if the dental arches were enlarged in obese OSA people who are thought to have a large tongue. We there...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.2011.02243.x

    authors: Maeda K,Tsuiki S,Isono S,Namba K,Kobayashi M,Inoue Y

    更新日期:2012-02-01 00:00:00

  • Fluoride ion diffusion from a glass-ionomer cement.

    abstract::The aims of this study were to observe the release of fluoride ions (F-) from GC-Fuji Lining-LC(R) glass-ionomer cement, to assess the diffusion process, and to measure fluoride diffusivity (D) in the set cement. Specimens of various dimensions and shapes, ranging from discs to cylindrical rods, were fabricated for bo...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1046/j.1365-2842.2000.00554.x

    authors: Lee SY,Dong DR,Huang HM,Shih YH

    更新日期:2000-07-01 00:00:00

  • A survey of treatment outcomes with removable partial dentures.

    abstract::The patient's satisfaction with removable partial denture (RPD) therapy has become an increasingly important factor in prosthetic treatment. This study examined patients' satisfaction with RPDs in relation to some socio-economic variables, patients' habits of wearing and cleaning RPDs, comfort of wearing RPDs and diff...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1046/j.1365-2842.2003.01039.x

    authors: Knezović Zlatarić D,Celebić A,Valentić-Peruzović M,Jerolimov V,Pandurić J

    更新日期:2003-08-01 00:00:00

  • Single-crystal sapphire endosseous dental implant loaded with functional stress--clinical and histological evaluation of peri-implant tissues.

    abstract::Peri-implant tissues of the single-crystal sapphire implant connected with neighbouring teeth by a metal bridge-work were examined clinically, radiographically, and histologically in ten monkeys. Professional tooth cleaning was performed during the study. At 3-12 months after insertion, most of the implants were firml...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1988.tb00147.x

    authors: Hashimoto M,Akagawa Y,Nikai H,Tsuru H

    更新日期:1988-01-01 00:00:00

  • A survey of U.K. centres on implant failures.

    abstract::This study investigated the experience of endossoseus implants in the U.K. - how success rates compare with other countries; the common causes of failure; early detection, definition and treatment of the failing implant. Information was gathered by means of a questionnaire sent to 120 centres in the U.K. Thirty-nine c...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章,多中心研究

    doi:10.1046/j.1365-2842.1999.00355.x

    authors: Tinsley D,Watson CJ,Ogden AR

    更新日期:1999-01-01 00:00:00

  • Studies on optical properties of two commercial visible-light-cured composite resins by diffuse reflectance measurements.

    abstract::Two commercial visible-light (VL)-cured composite resins were examined for their optical properties by diffuse reflectance measurements in VL spectrum and Kubelka-Munk's theory. Cured Silux Plus displayed diffuse reflectance similar to that of cured Z100, although uncured Silux Plus showed diffuse reflectance less tha...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1046/j.1365-2842.1999.00378.x

    authors: Taira M,Okazaki M,Takahashi J

    更新日期:1999-04-01 00:00:00

  • Use of sonographic elastography of the masseter muscles for optimizing massage pressure: a preliminary study.

    abstract::To examine the stiffness of the masseter muscle using sonographic elastography and to investigate its relationship with the most comfortable massage pressure in the healthy volunteers. In 16 healthy volunteers (10 men and 6 women), the Masseter Stiffness Index (MSI) was measured using EUB-7000 real-time tissue elastog...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.2009.01977.x

    authors: Ariji Y,Katsumata A,Hiraiwa Y,Izumi M,Iida Y,Goto M,Sakuma S,Ogi N,Kurita K,Ariji E

    更新日期:2009-09-01 00:00:00

  • Comparative wear ranking of dental restorative materials utilizing different wear simulation modes.

    abstract::The aim of this study was to compare the wear of seven different restorative materials using two different wear simulation modes. This included a non-impact sliding wear test (rotary pin and disc) and an impact-cum-sliding wear test (masticatory simulator). The difference in wear ranking between the two wear tests was...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1046/j.1365-2842.1997.00528.x

    authors: Yap AU,Teoh SH,Hastings GW,Lu CS

    更新日期:1997-08-01 00:00:00

  • Temporomandibular joint osteoarthritis: a comparative clinical and tomographic study pre- and post-treatment.

    abstract::Nineteen patients with definite and suspected temporomandibular joint (TMJ) osteoarthritis participated in this study. All patients were treated by dental care including bite plane therapy. By comparing the pre-treatment clinical symptoms and TMJ tomograms with those post-treatment, efficacy of the dental treatment ap...

    journal_title:Journal of oral rehabilitation

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1365-2842.1994.tb01153.x

    authors: Sato H,Fujii T,Yamada N,Kitamori H

    更新日期:1994-07-01 00:00:00

  • Functional evaluation after TMJ surgery.

    abstract::Oral function was evaluated in 30 patients (25 women and five men) after TMJ surgery by means of bite force measurements. Twenty-seven discectomies and three condylectomies had been performed. The follow-up period was, on average, 2.5 years. The mean bite force values on the function level 'biting as when chewing' was...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1995.tb01054.x

    authors: Widmark G,Haraldson T,Kahnberg KE

    更新日期:1995-08-01 00:00:00

  • The influence of stimulus type and stimulus strength on the silent period in human masticatory muscles.

    abstract::The silent period in the jaw-closing muscles of nine healthy subjects was investigated. The stimulus types used were the open-close-clench movement (OCC), the mechanical chin tap and electrical skin stimulation. Irrespective of the jaw-closing speed for the OCC movements only the unmeasurable and single type silent pe...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1984.tb00608.x

    authors: Kroon GW,Naeije M

    更新日期:1984-11-01 00:00:00

  • Obturator prostheses for hemimaxillectomy patients.

    abstract::Maxillary defects are created by surgical treatment of benign or malignant neoplasms, congenital malformation and by trauma. The size and location of the defects influence the degree of impairment and difficulty in prosthetic rehabilitation. Lack of support, retention, and stability are common prosthodontic treatment ...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2842.2001.00754.x

    authors: Keyf F

    更新日期:2001-09-01 00:00:00

  • Localization of lymph capillaries and blood capillaries in human temporomandibular joint discs.

    abstract::The localization of lymph capillaries and blood capillaries in the human temporomandibular joint (TMJ) discs was examined immunohistologically with anti-human collagen IV antibody and anti-human von Willebrand factor in 26 human TMJ samples. The 16 internal derangement cases were then compared with the 10 normal contr...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1046/j.1365-2842.1999.00402.x

    authors: Yoshida H,Fujita S,Nishida M,Iizuka T

    更新日期:1999-07-01 00:00:00

  • The effect of tooth clenching on the sensory and pain perception in the oro-facial region of symptom-free men and women.

    abstract::The aim of this study was (i) to examine the effect of light tooth contact as in diurnal tooth clenching on the tactile detection threshold (TDT), the filament-prick pain detection threshold (FPT) and the pressure pain threshold (PPT) in the oro-facial region and (ii) to examine the possible gender difference in this ...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.2009.01961.x

    authors: Okayasu I,Oi K,De Laat A

    更新日期:2009-07-01 00:00:00

  • Posterior palatal seal adaptation: influence of processing technique, palate shape and immersion.

    abstract::Accuracy of fit of denture bases is critical to adequate retention. This study compared the dimensional change of a newer continuous-injection technique with a standard trial-pack technique as determined by measuring the posterior palatal border opening. The influence of palate shape and immersion were also assessed. ...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1993.tb01511.x

    authors: Sykora O,Sutow EJ

    更新日期:1993-01-01 00:00:00

  • Correlation between autoregressive moving-average model parameters of electromyogram of human jaw closing muscles and maximum clenching time at intercuspal position.

    abstract::During maximum clenching in the intercuspal position, surface electromyograms of left masseter and anterior temporal muscles were sampled in 16 healthy subjects with natural dentitions to establish a four-order, autoregressive (AR) moving-average (MA) model of the myoelectrical signals. The correlation coefficients an...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1994.tb01170.x

    authors: Shi CS,Mao Y,Guo TW

    更新日期:1994-09-01 00:00:00

  • The selection of anterior teeth appropriate for the age and sex of the individual. How variable are dental staff in their choice?

    abstract::As part of the development of a guide to aid the undergraduate in the selection of artificial teeth, the aim of this study was to investigate the variability in choice of dental staff to select teeth appropriate to the age and sex of the individual with the aid of a series of three-dimensional guides. Four three-dimen...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1046/j.1365-2842.2002.00922.x

    authors: Sellen PN,Jagger DC,Harrison A

    更新日期:2002-09-01 00:00:00

  • Self-perceived oral health and salivary proteins in children with type 1 diabetes.

    abstract::The aim was to validate self-perceived oral health with salivary IgG as an inflammatory parameter in children with type 1 diabetes. Unstimulated whole saliva samples were collected from 36 children with well controlled and 12 with poorly controlled type 1 diabetes and 40 non-diabetic children (Controls). Salivary flow...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.2008.01895.x

    authors: Javed F,Sundin U,Altamash M,Klinge B,Engström PE

    更新日期:2009-01-01 00:00:00

  • Repair of glass ionomer cements--methods for conditioning the surface of the cement to achieve bonding.

    abstract::Two chemically different glass ionomer cements (Ketac Fil and ChemFil II Caps) and three different methods of conditioning the surface for repair were evaluated. Specimens of each material were prepared, aged and sectioned. The cut surfaces were treated with either phosphoric acid, polyacrylic acid or a combination of...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1994.tb01180.x

    authors: Jamaluddin A,Pearson GJ

    更新日期:1994-11-01 00:00:00

  • The temporal/masseter co-contraction: an electromyographic and clinical evaluation of short-term stabilization splint therapy in myogenous CMD patients.

    abstract::The short-term effect (3-6 weeks) of the use of a stabilization splint was investigated in a group of 35 myogenous craniomandibular disorder patients. The patients were clinically examined and surface EMG recordings of the temporal and masseter muscles were made during clenching in the intercuspal position (ICP), imme...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1111/j.1365-2842.1995.tb00789.x

    authors: Visser A,Naeije M,Hansson TL

    更新日期:1995-05-01 00:00:00

  • The effects of phosphoric acid, sodium hypochlorite, ferric oxalate and Scotchbond Multipurpose on the rate of pressure change across dentine: a laboratory study.

    abstract::The aim of this study was to investigate the consequences of dentine treatment on dentine permeability of crown preparations treated with phosphoric acid, sodium hypochlorite (NaOCl), and then ferric oxalate (Sensodyne sealant) or bis-phenol-A-diglycidyldimethacrylate (BIS-GMA) and hydroxyethylmethacrylate (HEMA) resi...

    journal_title:Journal of oral rehabilitation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2842.2005.01456.x

    authors: Ng LP,Wilson PR

    更新日期:2005-06-01 00:00:00

  • Fatigue resistance of removable orthodontic appliance reinforced with glass fibre weave.

    abstract::The aim of this study was to measure the fatigue resistance of fibre-reinforced composite (FRC) reinforced polymeric parts of a removable orthodontic appliance beside the clasp. The effect of quantity and position of FRC-reinforcement were investigated. In addition, the influence of water storage on the fatigue proper...

    journal_title:Journal of oral rehabilitation

    pub_type: 杂志文章

    doi:10.1046/j.1365-2842.2003.01108.x

    authors: Rantala LI,Lastumäki TM,Peltomäki T,Vallittu PK

    更新日期:2003-05-01 00:00:00