Abstract:
:Eumelanin is a ubiquitous biological pigment, and the origin of its broadband absorption spectrum has long been a topic of scientific debate. Here, we report a first-principles computational investigation to explain its broadband absorption feature. These computations are complemented by experimental results showing a broadening of the absorption spectra of dopamine solutions upon their oxidation. We consider a variety of eumelanin molecular structures supported by experiments or theoretical studies, and calculate the absorption spectra with proper account of the excitonic couplings based on the Frenkel exciton model. The interplay of geometric order and disorder of eumelanin aggregate structures broadens the absorption spectrum and gives rise to a relative enhancement of absorption intensity at the higher-energy end, proportional to the cube of absorption energy. These findings show that the geometric disorder model is as able as the chemical disorder model, and complements this model, to describe the optical properties of eumelanin.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Chen CT,Chuang C,Cao J,Ball V,Ruch D,Buehler MJdoi
10.1038/ncomms4859subject
Has Abstractpub_date
2014-05-22 00:00:00pages
3859issn
2041-1723pii
ncomms4859journal_volume
5pub_type
杂志文章abstract::Dynamic changes in histone modifications under various physiological cues play important roles in gene transcription and cancer. Identification of new histone marks critical for cancer development is of particular importance. Here we show that, in a glucose-dependent manner, E3 ubiquitin ligase NEDD4 ubiquitinates his...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14799
更新日期:2017-03-16 00:00:00
abstract::UV vision is prevalent, but we know little about its utility in common general tasks, as in resolving habitat structure. Here we visualize vegetated habitats using a multispectral camera with channels mimicking bird photoreceptor sensitivities across the UV-visible spectrum. We find that the contrast between upper and...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-08142-5
更新日期:2019-01-22 00:00:00
abstract::Diversity-oriented synthesis (DOS) can provide a collection of diverse and complex drug-like small molecules, which is critical in the development of new chemical probes for biological research of undruggable targets. However, the design and synthesis of small-molecule libraries with improved biological relevance as w...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13196
更新日期:2016-10-24 00:00:00
abstract::Visualization of ion transport in electrolytes provides fundamental understandings of electrolyte dynamics and electrolyte-electrode interactions. However, this is challenging because existing techniques are hard to capture low ionic concentrations and fast electrolyte dynamics. Here we show that stimulated Raman scat...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05289-z
更新日期:2018-07-30 00:00:00
abstract::Plants can produce organs throughout their entire life from pluripotent stem cells located at their growing tip, the shoot apical meristem (SAM). At the time of flowering, the SAM of Arabidopsis thaliana switches fate and starts producing flowers instead of leaves. Correct timing of flowering in part determines reprod...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15120
更新日期:2017-05-17 00:00:00
abstract::The diversity reflected by >100 different neural cell types fundamentally contributes to brain function and a central idea is that neuronal identity can be inferred from genetic information. Recent large-scale transcriptomic assays seem to confirm this hypothesis, but a lack of morphological information has limited th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20328-4
更新日期:2021-01-04 00:00:00
abstract::The Greenland ice sheet has become one of the main contributors to global sea level rise, predominantly through increased meltwater runoff. The main drivers of Greenland ice sheet runoff, however, remain poorly understood. Here we show that clouds enhance meltwater runoff by about one-third relative to clear skies, us...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10266
更新日期:2016-01-12 00:00:00
abstract::The midge, Belgica antarctica, is the only insect endemic to Antarctica, and thus it offers a powerful model for probing responses to extreme temperatures, freeze tolerance, dehydration, osmotic stress, ultraviolet radiation and other forms of environmental stress. Here we present the first genome assembly of an extre...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5611
更新日期:2014-08-12 00:00:00
abstract::Conventional lithium-ion batteries embrace graphite anodes which operate at potential as low as metallic lithium, subjected to poor rate capability and safety issues. Among possible alternatives, oxides based on titanium redox couple, such as spinel Li4Ti5O12, have received renewed attention. Here we further expand th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17233-1
更新日期:2020-07-13 00:00:00
abstract::The original version of this article contained an error in the author affiliations. Oliver J. Furzer was incorrectly associated with Department of Plant Sciences, College of Life Sciences, Wuhan University, 430072, Wuhan, China.This has now been corrected in the HTML version of the article. The PDF version of the arti...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-08095-9
更新日期:2019-01-08 00:00:00
abstract::Macrophages regulate host responses to implants through their dynamic adhesion, release, and activation. Herein, we employ bisphosphonate (BP)-coated gold nanoparticle template (BNP) to direct the swift and convertible formation of Mg2+-functional Mg2+-BP nanoparticle (NP) on the BP-AuNP surface via reversible Mg2+-BP...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09733-6
更新日期:2019-04-12 00:00:00
abstract::Artificial particle ices are model systems of constrained, interacting particles. They have been introduced theoretically to study ice-manifolds emergent from frustration, along with domain wall and grain boundary dynamics, doping, pinning-depinning, controlled transport of topological defects, avalanches, and memory ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06631-1
更新日期:2018-10-08 00:00:00
abstract::Mutant p53s (mutp53) increase cancer invasiveness by upregulating Rab-coupling protein (RCP) and diacylglycerol kinase-α (DGKα)-dependent endosomal recycling. Here we report that mutp53-expressing tumour cells produce exosomes that mediate intercellular transfer of mutp53's invasive/migratory gain-of-function by incre...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07339-y
更新日期:2018-11-29 00:00:00
abstract::The cell cytosol is crowded with high concentrations of many different biomacromolecules, which is difficult to mimic in bottom-up synthetic cell research and limits the functionality of existing protocellular platforms. There is thus a clear need for a general, biocompatible, and accessible tool to more accurately em...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20124-0
更新日期:2020-12-08 00:00:00
abstract::Sclerosing stromal tumor (SST) of the ovary is a rare type of sex cord-stromal tumor (SCST), whose genetic underpinning is currently unknown. Here, using whole-exome, targeted capture and RNA-sequencing, we report recurrent FHL2-GLI2 fusion genes in 65% (17/26) of SSTs and other GLI2 rearrangements in additional 15% (...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13806-x
更新日期:2020-01-02 00:00:00
abstract::In the original version of this Article, the title of the legend to Fig. 7 incorrectly read 'Knockdown of B55α increases breast cancer metastasis' instead of 'Knockdown of B55α decreases breast cancer metastasis'. This has now been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-06265-3
更新日期:2018-09-17 00:00:00
abstract::Selective thermal emission in a useful range of energies from a material operating at high temperatures is required for effective solar thermophotovoltaic energy conversion. Three-dimensional metallic photonic crystals can exhibit spectral emissivity that is modified compared with the emissivity of unstructured metals...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3630
更新日期:2013-01-01 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/s41467-020-15500-9
更新日期:2020-03-31 00:00:00
abstract::Memories link information about specific experiences to more general knowledge that is abstracted from and contextualizes those experiences. Hippocampal-cortical activity patterns representing features of past experience are reinstated during awake memory reactivation events, but whether representations of both specif...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-04498-w
更新日期:2018-06-07 00:00:00
abstract::The widespread CsrA/RsmA protein regulators repress translation by binding GGA motifs in bacterial mRNAs. CsrA activity is primarily controlled through sequestration by multiple small regulatory RNAs. Here we investigate CsrA activity control in the absence of antagonizing small RNAs by examining the CsrA regulon in t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11667
更新日期:2016-05-27 00:00:00
abstract::Approximately 30% of ERα breast cancer patients relapse with metastatic disease following adjuvant endocrine therapies. The connection between acquisition of drug resistance and invasive potential is poorly understood. In this study, we demonstrate that the type II keratin topological associating domain undergoes epig...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09676-y
更新日期:2019-05-09 00:00:00
abstract::Acoustic waves, capable of transmitting through optically opaque objects, have been widely used in biomedical imaging, industrial sensing and particle manipulation. High-fidelity wave front shaping is essential to further improve performance in these applications. An acoustic analog to the successful spatial light mod...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18347-2
更新日期:2020-09-10 00:00:00
abstract::Past studies of the end-Permian extinction (EPE), the largest biotic crisis of the Phanerozoic, have not resolved the timing of events in southern high-latitudes. Here we use palynology coupled with high-precision CA-ID-TIMS dating of euhedral zircons from continental sequences of the Sydney Basin, Australia, to show ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07934-z
更新日期:2019-01-23 00:00:00
abstract::CDKL5 deficiency disorder (CDD) is characterized by epilepsy, intellectual disability, and autistic features, and CDKL5-deficient mice exhibit a constellation of behavioral phenotypes reminiscent of the human disorder. We previously found that CDKL5 dysfunction in forebrain glutamatergic neurons results in deficits in...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10689-w
更新日期:2019-06-14 00:00:00
abstract::Neurodegenerative lesions induce sprouting of new collaterals from surviving axons, but the extent to which this form of axonal remodelling alters brain functional structure remains unclear. To understand how collateral sprouting proceeds in the adult brain, we imaged post-lesion sprouting of cerebellar climbing fibre...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12938
更新日期:2016-09-21 00:00:00
abstract::The Mott metal-insulator transition-a manifestation of Coulomb interactions among electrons-is known as a discontinuous transition. Recent theoretical studies, however, suggest that the transition is continuous if the Mott insulator carries a spin liquid with a spinon Fermi surface. Here, we demonstrate the case of a ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02679-7
更新日期:2018-01-22 00:00:00
abstract::Solar radio observations provide a unique diagnostic of the outer solar atmosphere. However, the inhomogeneous turbulent corona strongly affects the propagation of the emitted radio waves, so decoupling the intrinsic properties of the emitting source from the effects of radio wave propagation has long been a major cha...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01307-8
更新日期:2017-11-15 00:00:00
abstract::The same odorant can induce attractive or repulsive responses depending on its concentration in various animals including humans. However, little is understood about the neuronal basis of this behavioural phenomenon. Here we show that Caenorhabditis elegans avoids high concentrations of odorants that are attractive at...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1750
更新日期:2012-03-13 00:00:00
abstract::It is commonly assumed that neural systems efficiently process natural sensory input. However, the mechanisms by which such efficient processing is achieved, and the consequences for perception and behaviour remain poorly understood. Here we show that small conductance calcium-activated potassium (SK) channels enable ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11353
更新日期:2016-04-18 00:00:00
abstract::This corrects the article DOI: 10.1038/ncomms14454. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/ncomms16007
更新日期:2017-06-23 00:00:00