Abstract：
:The development of the DNA theory of inheritance culminated in the publication of the molecular structure of DNA 60 years ago. This paper describes this development, beginning with the discovery of DNA as a chemical substance by Friedrich Miescher in 1869, followed by its basic chemical analysis and demonstration of its participation in the structure of chromosomes. Subsequently it was discovered by Oswald Avery in 1944 that DNA was the genetic material, and then Erwin Chargaff showed that the proportions of the bases included in the structure of DNA followed a certain law. These findings, in association with the biophysical studies of Maurice Wilkins and Rosalind Franklin with Raymond Gosling, led James Watson and Francis Crick to the discovery of the double-helical structure of DNA in 1953. The paper ends with a short description of the development of the DNA theory of inheritance after the discovery of the double helix.
journal_name
J Genetjournal_title
Journal of geneticsauthors
Portin Pdoi
10.1007/s12041-014-0337-4subject
Has Abstractpub_date
2014-04-01 00:00:00pages
293-302issue
1eissn
0022-1333issn
0973-7731journal_volume
93pub_type
历史文章,杂志文章,评审abstract：:Multiple experimental evolution studies on Drosophila melanogaster in the 1980s and 1990s indicated that enhanced competitive ability evolved primarily through increased larval tolerance to nitrogenous wastes and increased larval feeding and foraging rate, at the cost of efficiency of food conversion to biomass, and t...
journal_title：Journal of genetics
pub_type： 杂志文章
doi：10.1007/s12041-016-0656-8
更新日期：2016-09-01 00:00:00
abstract：:Molecular characterization of 23 cytogenetically confirmed XY females was attempted by screening coding regions of SRY and androgen receptor (AR) genes. Five of the index cases showed sequence variations in various exons of the AR gene: a deletion (n.1911delG) and substitutions n.1761G>A and n.1317C>T in exon 1; n.351...
journal_title：Journal of genetics
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doi：10.1007/s12041-016-0716-0
更新日期：2016-12-01 00:00:00
abstract：:Central Himalayan region of India encompasses varied ecological habitats ranging from near tropics to the mid-elevation forests dominated by cool-temperate taxa. In past, we have reported several new records and novel species from Uttarakhand state of India. Here, we assessed genetic variations in three mitochondrial ...
journal_title：Journal of genetics
pub_type： 杂志文章
doi：10.1007/s12041-016-0646-x
更新日期：2016-06-01 00:00:00
abstract：:Eucalyptus is an important short rotation pulpy woody plant, grown widely in the tropics. Recently, many genomic programmes are underway leading to the accumulation of voluminous genomic and expressed sequence tag sequences in public databases. These sequences can be utilized for analysis of simple sequence repeats (S...
journal_title：Journal of genetics
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doi：10.1007/s12041-008-0003-9
更新日期：2008-04-01 00:00:00
abstract：:Association mapping is a powerful high-resolution mapping tool for complex traits. The objective of this study was to identify QTLs for partial resistance to Phytophthora sojae. In this study, we evaluated a total of 214 soybean accessions by the hypocotyl inoculation method, and 175 were susceptible. The 175 suscepti...
journal_title：Journal of genetics
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doi：10.1007/s12041-014-0383-y
更新日期：2014-08-01 00:00:00
abstract：:ABC (ATP-binding cassette) transporters are members of a large superfamily of proteins that utilize ATP hydrolysis to translocate a wide range of substrates across biological membranes. In general, members of C subfamily (ABCC) are structurally characterized by an additional (N-terminal) transmembrane domain (TMD0). P...
journal_title：Journal of genetics
pub_type： 杂志文章
doi：10.1007/s12041-014-0327-6
更新日期：2014-04-01 00:00:00
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journal_title：Journal of genetics
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journal_title：Journal of genetics
pub_type： 杂志文章
doi：10.1007/BF02935327
更新日期：2006-12-01 00:00:00
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journal_title：Journal of genetics
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更新日期：2019-03-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章
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更新日期：2018-12-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章,评审
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更新日期：2017-07-01 00:00:00
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journal_title：Journal of genetics
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更新日期：2018-03-01 00:00:00
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journal_title：Journal of genetics
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doi：
更新日期：2019-06-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章
doi：10.1007/BF02717907
更新日期：2001-12-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章
doi：10.1007/s12041-016-0738-7
更新日期：2017-03-01 00:00:00
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journal_title：Journal of genetics
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doi：
更新日期：2018-03-01 00:00:00
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journal_title：Journal of genetics
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更新日期：2019-09-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章
doi：10.1007/s12041-013-0271-x
更新日期：2013-12-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章
doi：10.1007/s12041-009-0030-1
更新日期：2009-08-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章
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更新日期：2012-08-01 00:00:00
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pub_type： 杂志文章,评审
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journal_title：Journal of genetics
pub_type： 杂志文章
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更新日期：2003-04-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章,多中心研究
doi：
更新日期：2018-03-01 00:00:00
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journal_title：Journal of genetics
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更新日期：2020-01-01 00:00:00
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journal_title：Journal of genetics
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更新日期：2017-09-01 00:00:00
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journal_title：Journal of genetics
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更新日期：2016-03-01 00:00:00
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journal_title：Journal of genetics
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更新日期：2018-12-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章
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更新日期：2016-12-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章
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更新日期：2014-12-01 00:00:00
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journal_title：Journal of genetics
pub_type： 杂志文章
doi：
更新日期：2019-11-01 00:00:00
