Abstract:
:The integration of nanophotonics and atomic physics has been a long-sought goal that would open new frontiers for optical physics, including novel quantum transport and many-body phenomena with photon-mediated atomic interactions. Reaching this goal requires surmounting diverse challenges in nanofabrication and atomic manipulation. Here we report the development of a novel integrated optical circuit with a photonic crystal capable of both localizing and interfacing atoms with guided photons. Optical bands of a photonic crystal waveguide are aligned with selected atomic transitions. From reflection spectra measured with average atom number N=1.1+/-0.4, we infer that atoms are localized within the waveguide by optical dipole forces. The fraction of single-atom radiative decay into the waveguide is Γ1D/Γ'≃(0.32±0.08), where Γ1D is the rate of emission into the guided mode and Γ' is the decay rate into all other channels. Γ1D/Γ' is unprecedented in all current atom-photon interfaces.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Goban A,Hung CL,Yu SP,Hood JD,Muniz JA,Lee JH,Martin MJ,McClung AC,Choi KS,Chang DE,Painter O,Kimble HJdoi
10.1038/ncomms4808subject
Has Abstractpub_date
2014-05-08 00:00:00pages
3808issn
2041-1723pii
ncomms4808journal_volume
5pub_type
杂志文章abstract::The high incidence of aneuploidy in the embryo is considered the principal cause for low human fecundity. However, the prevalence of aneuploidy dramatically declines as pregnancy progresses, with the steepest drop occurring as the embryo completes implantation. Despite the fact that the plasticity of the embryo in dea...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16796-3
更新日期:2020-06-11 00:00:00
abstract::The alloy-design strategy of combining multiple elements in near-equimolar ratios has shown great potential for producing exceptional engineering materials, often known as 'high-entropy alloys'. Understanding the elemental distribution, and, thus, the evolution of the configurational entropy during solidification, is ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6964
更新日期:2015-01-20 00:00:00
abstract::Controlling the transmission of electrical current using a quantum point contact constriction paved a way to a large variety of experiments in mesoscopic physics. The increasing interest in heat transfer in such systems fosters questions about possible manipulations of quantum heat modes that do not carry net charge (...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02433-z
更新日期:2017-12-21 00:00:00
abstract::Human chromosomes are captured along microtubule walls (lateral attachment) and then tethered to microtubule-ends (end-on attachment) through a multi-step end-on conversion process. Upstream regulators that orchestrate this remarkable change in the plane of kinetochore-microtubule attachment in human cells are not kno...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00209-z
更新日期:2017-07-28 00:00:00
abstract::Future energy demand is likely to increase due to climate change, but the magnitude depends on many interacting sources of uncertainty. We combine econometrically estimated responses of energy use to income, hot and cold days with future projections of spatial population and national income under five socioeconomic sc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10399-3
更新日期:2019-06-24 00:00:00
abstract::The emergence of personalized and stratified medicine requires label-free, low-cost diagnostic technology capable of monitoring multiple disease biomarkers in parallel. Silicon photonic biosensors combine high-sensitivity analysis with scalable, low-cost manufacturing, but they tend to measure only a single biomarker ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12769
更新日期:2016-09-14 00:00:00
abstract::Transition metal catalyzed Sonogashira cross-coupling of terminal alkynes with aryl(vinyl) (pseudo)halides has been successfully extended to alkyl halides for the synthesis of functionalized internal alkynes. The direct alkynylation of remote unfunctionalized sp3 carbon by terminal alkynes remains difficult to realize...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14292-2
更新日期:2020-01-21 00:00:00
abstract::Rather than targeting tumour cells directly, elements of the tumour microenvironment can be modulated to sensitize tumours to the effects of therapy. Here we report a unique mechanism by which ectopic microRNA-103 can manipulate tumour-associated endothelial cells to enhance tumour cell death. Using gain-and-loss of f...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13597
更新日期:2016-11-25 00:00:00
abstract::In many dynamical systems and complex networks time delays appear naturally in feedback loops or coupling connections of individual elements. Moreover, in a whole class of systems, these delay times can depend on the state of the system. Nevertheless, so far the understanding of the impact of such state-dependent dela...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8425
更新日期:2015-06-17 00:00:00
abstract::A variety of flexible and stretchable electronics have been reported for use in flexible electronic devices or biomedical applications. The practical and wider application of such flexible electronics has been limited because commercial electronic components are difficult to be directly integrated into flexible stretc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1980
更新日期:2012-01-01 00:00:00
abstract::Metastasis is the main cause of cancer-related death and thus understanding the molecular and cellular mechanisms underlying this process is critical. Here, our data demonstrate, contrary to established dogma, that loss of haematopoietic-derived focal adhesion kinase (FAK) is sufficient to enhance tumour metastasis. U...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6054
更新日期:2014-10-01 00:00:00
abstract::In adult skin epidermis and the epithelium lining the esophagus cells are constantly shed from the tissue surface and replaced by cell division. Tracking genetically labelled cells in transgenic mice has given insight into cell behavior, but conflicting models appear consistent with the results. Here, we use an additi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15258-0
更新日期:2020-03-18 00:00:00
abstract::Traumatic spinal cord injury results in severe and irreversible loss of function. The injury triggers a complex cascade of inflammatory and pathological processes, culminating in formation of a scar. While traditionally referred to as a glial scar, the spinal injury scar in fact comprises multiple cellular and extrace...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/s41467-019-11707-7
更新日期:2019-08-28 00:00:00
abstract::The quantum spin Hall (QSH) phase is an exotic phenomena in condensed-matter physics. Here we show that a minimal basis of three orbitals (s, px, py) is required to produce a QSH phase via nearest-neighbour hopping in a two-dimensional trigonal lattice. Tight-binding model analyses and calculations show that the QSH p...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12746
更新日期:2016-09-07 00:00:00
abstract::MCR-1 is a lipid A modifying enzyme that confers resistance to the antibiotic colistin. Here, we analyse the impact of MCR-1 expression on E. coli morphology, fitness, competitiveness, immune stimulation and virulence. Increased expression of mcr-1 results in decreased growth rate, cell viability, competitive ability ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02149-0
更新日期:2017-12-12 00:00:00
abstract::Heterogeneous catalysis is an enabling technology that utilises transition metal nanoparticles (NPs) supported on oxides to promote chemical reactions. Structural mismatch at the NP-support interface generates lattice strain that could affect catalytic properties. However, detailed knowledge about strain in supported ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05055-1
更新日期:2018-07-13 00:00:00
abstract::An incorrect version of the Supplementary Information was inadvertently published with this Article. The HTML has now been updated to include the correct version of the Supplementary Information. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-017-01617-x
更新日期:2017-11-23 00:00:00
abstract::Gut-associated inflammation plays a crucial role in the progression of colon cancer. Here, we identify a novel pathogen-host interaction that promotes gut inflammation and the development of colon cancer. We find that enteropathogenic bacteria-secreted particles (ET-BSPs) stimulate intestinal epithelium to produce IDE...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7956
更新日期:2015-04-24 00:00:00
abstract::Flexible organic memory devices are one of the integral components for future flexible organic electronics. However, high-density all-organic memory cell arrays on malleable substrates without cross-talk have not been demonstrated because of difficulties in their fabrication and relatively poor performances to date. H...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3707
更新日期:2013-01-01 00:00:00
abstract::Activation of innate immunity by membrane-localized receptors is conserved across eukaryotes. Plant genomes contain hundreds of such receptor-like genes and those encoding proteins with an extracellular leucine-rich repeat (LRR) domain represent the largest family. Here, we develop a high-throughput approach to study ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03010-8
更新日期:2018-02-09 00:00:00
abstract::The host-guest recognition between two macrocycles to form hierarchical non-intertwined ring-in-ring assemblies remains an interesting and challenging target in noncovalent synthesis. Herein, we report the design and characterization of a box-in-box assembly on the basis of host-guest radical-pairing interactions betw...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07673-1
更新日期:2018-12-10 00:00:00
abstract::Direct cross-coupling between simple arenes and heterocyclic amines under mild conditions is undoubtedly important for C-N bonds construction. Selective C(sp2)-H amination is more valuable. Herein we show a selective C(sp2)-H amination of arenes (alkyl-substituted benzenes, biphenyl and anisole derivatives) accompanie...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14226
更新日期:2017-02-01 00:00:00
abstract::Heterostructures formed by stacking layered materials require atomically clean interfaces. However, contaminants are usually trapped between the layers, aggregating into randomly located blisters, incompatible with scalable fabrication processes. Here we report a process to remove blisters from fully formed heterostru...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07558-3
更新日期:2018-12-19 00:00:00
abstract::Bacterial autotransporters comprise a 12-stranded membrane-embedded β-barrel domain, which must be folded in a process that entraps segments of an N-terminal passenger domain. This first stage of autotransporter folding determines whether subsequent translocation can deliver the N-terminal domain to its functional for...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5239
更新日期:2014-06-26 00:00:00
abstract::Environmental challenges to plants typically entail retardation of vegetative growth and delay or cessation of flowering. Here we report a link between the flowering time regulator, GIGANTEA (GI), and adaptation to salt stress that is mechanistically based on GI degradation under saline conditions, thus retarding flow...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2357
更新日期:2013-01-01 00:00:00
abstract::The early diversification of animals (∼ 630 Ma), and their development into both motile and macroscopic forms (∼ 575-565 Ma), has been linked to stepwise increases in the oxygenation of Earth's surface environment. However, establishing such a linkage between oxygen and evolution for the later Cambrian 'explosion' (54...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8142
更新日期:2015-05-18 00:00:00
abstract::Stimulation of TNFR1 by TNFα can promote three distinct alternative mechanisms of cell death: necroptosis, RIPK1-independent and -dependent apoptosis. How cells decide which way to die is unclear. Here, we report that TNFα-induced phosphorylation of RIPK1 in the intermediate domain by TAK1 plays a key role in regulati...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00406-w
更新日期:2017-08-25 00:00:00
abstract::The Gibbs energy, G, determines the equilibrium conditions of chemical reactions and materials stability. Despite this fundamental and ubiquitous role, G has been tabulated for only a small fraction of known inorganic compounds, impeding a comprehensive perspective on the effects of temperature and composition on mate...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06682-4
更新日期:2018-10-09 00:00:00
abstract::Reversible acetylation of α-tubulin is an evolutionarily conserved modification in microtubule networks. Despite its prevalence, the physiological function and regulation of microtubule acetylation remain poorly understood. Here we report that macrophages challenged by bacterial lipopolysaccharides (LPS) undergo exten...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4479
更新日期:2014-03-17 00:00:00
abstract::The Earth's biggest magmatic events are believed to originate from massive melting when hot mantle plumes rising from the lowermost mantle reach the base of the lithosphere. Classical models predict large plume heads that cause kilometre-scale surface uplift, and narrow (100 km radius) plume tails that remain in the m...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7960
更新日期:2015-04-24 00:00:00