Abstract:
AIMS:To examine the relationship between statin use in Chinese patients with intracerebral hemorrhage (ICH) during their hospitalization and the outcomes. METHODS:Data were collected from the China National Stroke Registry. Good functional outcome was defined by a modified Rankin Scale score between 0-2. Functional outcome and rate of mortality at 3 months and 1 year were compared between ICH patients on statin and those without it during their hospitalization. Odds ratios (ORs) with 95% confidence intervals (CI) were calculated using the multivariable logistic regression model adjusted for baseline risk factors. RESULTS:Among 3218 consecutive ICH patients from 2007 to 2008, 220 (6.8%) were on statin during their hospitalization. Compared with those without statin, patients on statin were younger, had more stroke risk factors but lower stroke severity. ICH patients on statin had better functional outcome at 3 months (OR 2.24, 95% CI 1.49-3.36) and at 1 year (OR 2.04, 95% CI 1.37-3.06). They also had lower rate of mortality at 3 months (OR 0.44, 95% CI 0.22-0.87) and 1 year (OR 0.49, 95% CI 0.27-0.86). CONCLUSIONS:In-hospital statin use in ICH patients is associated with better functional outcome and lower mortality at 3 months and 1 year.
journal_name
CNS Neurosci Therjournal_title
CNS neuroscience & therapeuticsauthors
Pan YS,Jing J,Wang YL,Zhao XQ,Song B,Wang WJ,Wang D,Liu GF,Liu LP,Wang CX,Wang YJ,CNSR investigators.doi
10.1111/cns.12274subject
Has Abstractpub_date
2014-06-01 00:00:00pages
548-55issue
6eissn
1755-5930issn
1755-5949journal_volume
20pub_type
杂志文章abstract::We will review all available studies on the use of lacosamide in the treatment of partial-onset seizures. The available evidence includes two open-label studies and three randomized controlled trials evaluating the safety and efficacy of oral lacosamide. One open-label study and one randomized controlled trial evaluat...
journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章,评审
doi:10.1111/j.1755-5949.2010.00198.x
更新日期:2011-12-01 00:00:00
abstract::Stroke is a leading cause of death that affects 15 million people worldwide each year. Increasing evidence suggests that stroke confers substantial risk for suicide and following a stroke, patients frequently develop poststroke depression, which is a well-established risk factor for suicide. In this overview of the cu...
journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章,评审
doi:10.1111/j.1755-5949.2012.00364.x
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章,评审
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章
doi:10.1111/cns.12983
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journal_title:CNS neuroscience & therapeutics
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章,多中心研究
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journal_title:CNS neuroscience & therapeutics
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章,评审
doi:10.1111/j.1755-5949.2010.00146.x
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pub_type: 杂志文章,随机对照试验
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章,评审
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journal_title:CNS neuroscience & therapeutics
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pub_type: 杂志文章,评审
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章
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journal_title:CNS neuroscience & therapeutics
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journal_title:CNS neuroscience & therapeutics
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更新日期:2018-10-01 00:00:00
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章
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journal_title:CNS neuroscience & therapeutics
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章,评审
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更新日期:2013-09-01 00:00:00
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章
doi:10.1111/j.1755-5949.2012.00312.x
更新日期:2012-06-01 00:00:00
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journal_title:CNS neuroscience & therapeutics
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journal_title:CNS neuroscience & therapeutics
pub_type: 杂志文章
doi:10.1111/cns.13064
更新日期:2019-02-01 00:00:00
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journal_title:CNS neuroscience & therapeutics
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