Immunosuppressive treatment of multiple sclerosis.

Abstract:

:Multiple sclerosis is thought, by many investigators, to be an immunologic disease. Therefore, a rationale exists for treating this disease by immunosuppressive therapy. In exacerbating-remitting multiple sclerosis, corticosteroids and adrenocorticotropic hormone are the most widely used drugs; high doses of intravenously administered methylprednisolone have recently gained favor. Chronic progressive multiple sclerosis has been treated with a number of immunosuppressive regimens, several of which have shown promise to date. Cyclophosphamide and azathioprine have been used most often and are reviewed in this report, as are other agents currently under investigation. No firm guidelines for the treatment of chronic progressive multiple sclerosis can be offered, but an approach to immunosuppressive therapy is suggested in this review.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Carter JL,Rodriguez M

doi

10.1016/s0025-6196(12)65345-2

subject

Has Abstract

pub_date

1989-06-01 00:00:00

pages

664-9

issue

6

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(12)65345-2

journal_volume

64

pub_type

临床试验,杂志文章,评审
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    更新日期:1992-07-01 00:00:00

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    pub_type: 杂志文章

    doi:

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    abstract::Advances in liver transplantation continue to evolve but are hampered by continued increasing shortages in donor organs. This has resulted in a high incidence of patients dying while on the United Network for Organ Sharing waiting list. Indeed, we continue to assess ways of expanding the donor pool by using marginal d...

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    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

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    pub_type: 杂志文章

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    doi:10.4065/71.1.37

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