Abstract:
:The afferent inputs to the rostral pole of the anterior pretectal nucleus have been examined by utilizing the retrograde axonal transport of a fluorescent dye, Fast Blue. After unilateral injection of the dye into the rostral anterior prectectal nucleus, large numbers of labelled neuronal somata were found in the somatosensory cortex, the ventrolateral geniculate nucleus, the zona incerta, the superior colliculus, the deep mesencephalic nuclei, the pedunculopontine tegmental nucleus and the medial vestibular nucleus. In addition, the contralateral parabigeminal nucleus provided a major input to the rostral part of the anterior pretectal nucleus. Smaller and sparser collections of stained cell bodies could be found in the ventromedial hypothalamus, the posterior pretectal nucleus, the nucleus of the posterior commissure, the peripeduncular nucleus, the periaqueductal central gray, the contralateral anterior pretectal nucleus, and the locus coeruleus. Many of the inputs originated in areas associated with nociceptive pathways. The regional distribution of neurons projecting to the rostral pole of the anterior pretectal nucleus differs substantially from that of the cells innervating the anterior pretectal nucleus proper, i.e. its more caudal parts. It is concluded from this that the rostral pole constitutes a separate nucleus, anatomically distinct from the rest of the anterior pretectal nucleus and other cell groups in the pretectal complex. The demonstration that many of the afferents to the rostral anterior pretectal nucleus arise in regions involved in nociception supports recent electrophysiological and behavioural evidence that this brain area plays a role in the processing of noxious stimuli, rather than as a component in the pretectal control of visual system reflexes.
journal_name
Neurosciencejournal_title
Neuroscienceauthors
Foster GA,Sizer AR,Rees H,Roberts MHdoi
10.1016/0306-4522(89)90141-3subject
Has Abstractpub_date
1989-01-01 00:00:00pages
685-94issue
3eissn
0306-4522issn
1873-7544pii
0306-4522(89)90141-3journal_volume
29pub_type
杂志文章相关文献
NEUROSCIENCE文献大全abstract::Administration of selective agonists of D1 dopamine receptors increases immediate early gene expression in striatal neurons, a response which is particularly robust in the dopamine-depleted striatum. Although interactions between dopamine and glutamate receptor-mediated responses in striatal neurons have been demonstr...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(98)00327-3
更新日期:1999-03-01 00:00:00
abstract::The available data on the innervation of the thoracolumbar fascia (TLF) are inconsistent and partly contradictory. Therefore, the role of the fascia as a potential source of pain in the low back is difficult to assess. In the present study, a quantitative evaluation of calcitonin gene-related peptide (CGRP) and substa...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2011.07.066
更新日期:2011-10-27 00:00:00
abstract::We have examined the relationship between brain-derived neurotrophic factor gene expression in the hippocampus and memory retention as well as long-term potentiation of rats. One-way inhibitory avoidance learning was adopted as the behavioural paradigm. Results revealed that brain-derived neurotrophic factor messenger...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(97)00325-4
更新日期:1998-02-01 00:00:00
abstract::Normal adult cerebellar Purkinje cells in the rat rarely express low-affinity nerve growth factor receptor immunoreactivity. However, intense anti-low-affinity nerve growth factor receptor immunostaining was observed as early as one day after a lesion of the cerebellar cortex. Low-affinity nerve growth factor receptor...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(93)90408-8
更新日期:1993-02-01 00:00:00
abstract::It is now well established that vestibular information plays an important role in spatial memory processes. Although vestibular lesions induce anxiety in humans, this finding remains controversial in rodents. However, it is possible that anxiety-related behavior is associated with spatial memory impairments after vest...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2012.05.029
更新日期:2012-08-30 00:00:00
abstract::In mammals, the extraocular muscle fibers can be categorized in singly-innervated and multiply-innervated muscle fibers. In the monkey oculomotor, trochlear and abducens nucleus the motoneurons of multiply-innervated muscle fibers lie separated from those innervating singly-innervated muscle fibers and show different ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2005.10.038
更新日期:2006-02-01 00:00:00
abstract::Electrophysiological and anatomical studies were carried out in parallel to investigate the ability of lateral geniculate body neurons to regenerate axons damaged by the removal of the primary visual cortex and to innervate graft neurons functionally after transplantation of fetal neocortical tissue to a lesion cavity...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(94)90278-x
更新日期:1994-06-01 00:00:00
abstract::There is evidence of structural and functional deterioration in the brain, including the prefrontal cortex (PFC) and hippocampus, during the normal aging process in animals and humans. Extracellular matrix-associated glycoproteins, such as chondroitin sulfate proteoglycans (CSPGs), are involved in not only maintaining...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2009.08.060
更新日期:2009-12-15 00:00:00
abstract::Tissue injury results in several changes in spinal cord neurons that contribute to hyperalgesia arising from the injured tissue. In models of unilateral hindpaw inflammation, changes in the neurochemistry and electrophysiology of dorsal horn neurons ipsilateral, and to a much lesser extent contralateral, to the inflam...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(92)90290-i
更新日期:1992-12-01 00:00:00
abstract::The majority of work examining the nucleus accumbens core (NAc) has focused on functions pertaining to behaviors guided by appetitive outcomes. These studies have pointed to the NAc as being critical for motivating behavior toward desirable outcomes. For example, we have recently shown that lesions of the NAc impaired...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2013.11.028
更新日期:2014-01-31 00:00:00
abstract::Neurotoxicity of (2S,1'R,2'R,3'R)-2-(2,3-dicarboxycyclopropyl)glycine (DCG-IV), a potent agonist for metabotropic glutamate receptors negatively coupled to adenylyl cyclase, was investigated in vivo by the intraventricular administration in the rat, compared with that of (2S,1'S,2'S)-2-(carboxycyclopropyl)glycine (L-C...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(96)00043-7
更新日期:1996-08-01 00:00:00
abstract::Our previous studies on olfactory bulbar responses in salmonid fishes suggest that pheromone signals might be processed by a mechanism distinct from that of other odorants. Using in vivo single-unit and electroencephalographic recordings, we investigated response characteristics of olfactory neurons in lake whitefish,...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(02)00717-0
更新日期:2003-01-01 00:00:00
abstract::We explored the contribution of inhibitory peanut-binding extracellular matrix glycoproteins to the regeneration of characteristic outgrowth patterns by different types of identified neurons. Adult leech neurons were isolated one by one and plated in culture on a substrate that consisted of the capsules that encase th...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2005.10.036
更新日期:2006-01-01 00:00:00
abstract::Previous studies have raised the possibility that a decrease in voltage-gated K+ currents may contribute to hyperexcitability of injured dorsal root ganglion (DRG) neurons and the emergence of neuropathic pain. We examined the effects of axotomy on mRNA levels for various Kv1 family subunits and voltage-gated K+ curre...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2003.11.014
更新日期:2004-01-01 00:00:00
abstract::A dysfunction of noradrenergic mechanisms originating in the locus coeruleus has been hypothesised to be the critical factor underlying the evolution of central neurodegenerative diseases [Colpaert FC (1994) Noradrenergic mechanism Parkinson's disease: a theory. In: Noradrenergic mechanisms in Parkinson's disease (Bri...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(02)00757-1
更新日期:2003-01-01 00:00:00
abstract::Binding of cyclic AMP to the regulatory subunit of cyclic AMP-dependent protein kinase is an essential step in cyclic AMP-mediated intracellular signal transduction. In the present study, the binding capacity of cyclic AMP-dependent protein kinase for cyclic AMP was examined by autoradiography with local cerebral bloo...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(99)00314-0
更新日期:1999-01-01 00:00:00
abstract::Iron may catalyse the production of reactive oxygen species during post-ischemic reoxygenation and subsequently lead to brain damage. Ferritin, an iron sequestering and storage protein, can also be a source of iron after ischemic insult. However, its role in ischemia-reperfusion has not been carefully investigated. In...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(00)00317-1
更新日期:2000-01-01 00:00:00
abstract::Dephosphin/dynamin is a 94,000/96,000 mol. wt protein kinase C substrate from rat brain that is phosphorylated in nerve terminals and dephosphorylated upon stimulation of exocytosis and synaptic vesicle recycling. Phosphorylation activates an intrinsic GTPase activity and dephosphin may play a role in endocytosis [Rob...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(94)00337-5
更新日期:1995-02-01 00:00:00
abstract::Population-based studies have demonstrated that children with a history of febrile seizure (FS) perform better than age-matched controls at hippocampus-dependent memory tasks. Here, we report that FSs induce two distinct structural reorganizations in the hippocampus and bidirectionally modify future learning abilities...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2016.01.011
更新日期:2016-03-24 00:00:00
abstract::Mast cells and their location in the cat lateral geniculate complex of the thalamus were examined by means of histamine immunohistochemistry and the mast cell stain pinacyanol erythrosinate. Brain sections from seven normal adult pigmented cats were processed for light or electron microscopy. Histamine-containing and ...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(94)90016-7
更新日期:1994-11-01 00:00:00
abstract::The aim of the present work was to investigate the mechanism by which the diffusible factor nitric oxide regulates GABAA receptor function in the brain. The effect of nitric oxide on GABAA receptor function has been studied in two different neuronal preparations: rat cerebral cortex microsacs and rat cerebellum granul...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(96)00110-8
更新日期:1996-09-01 00:00:00
abstract::Neural activity varies continually from moment to moment. Such temporal variability (TV) has been highlighted as a functionally specific brain property playing a fundamental role in cognition. We sought to investigate the mechanisms involved in TV changes between two basic behavioral states, namely having the eyes ope...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2018.02.041
更新日期:2018-05-21 00:00:00
abstract::The role of the cerebral cortex in maintaining human standing balance remains unclear. Beta corticomuscular coherence (CMC) provides a measure of communication between the sensory-motor cortex and muscle, but past literature has not demonstrated significant beta CMC during human stance. This study evaluated the effect...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2015.04.009
更新日期:2015-07-09 00:00:00
abstract::Toll-like receptor 2 (TLR2) and TLR4 belong to a family of highly conserved pattern recognition receptors and are well-known upstream sensors of signaling pathways of innate immunity. TLR2 and TLR4 upregulation is thought to be associated with poor outcome in stroke patients. We currently show that transient focal isc...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2018.01.014
更新日期:2018-03-01 00:00:00
abstract::On guinea-pig neocortical slices the spatial organization of dendrites sensitive to excitatory amino acids was studied. Extracellular recording were obtained from the the soma of layer V neurons. Responses of 135 neurons to iontophoretically applied glutamate or aspartate have been analysed. An increased firing rate t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/0306-4522(95)00189-p
更新日期:1995-11-01 00:00:00
abstract::We examined the expression of SIRT1 in several experimental paradigms of human pathologies. We used a neuroblastoma cell line (B65), neuronal primary cultures (hippocampus and cerebellar granule cells) and in vivo approaches in rat and senescence murine models (SAM). Cell cultures and rats were treated with several we...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2008.04.065
更新日期:2008-07-17 00:00:00
abstract::Numerous epidemiological studies have shown an association between pesticide exposure and the increased risk of developing Parkinson's disease. Previously we have reported that Dichlorvos exposure can induce oxidative stress, resulting in over-expression of pro-apoptotic genes and finally caspase-dependent nigrostriat...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2013.11.004
更新日期:2014-01-31 00:00:00
abstract::Androgens are known to affect cognitive and mnemonic aspects of spatial processing. The cholinergic system is thought to play an important role in cognition and memory, but little is known about the interaction between androgen and cholinergic neurons. The present study focused on the effects of testosterone on the ch...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(01)00513-9
更新日期:2002-01-01 00:00:00
abstract::We have shown that cortical acetylcholine modulates the balance between excitation and inhibition evoked in layer 5 pyramidal neurons of rat visual cortex [Lucas-Meunier E, Monier C, Amar M, Baux G, Frégnac Y, Fossier P (2009) Cereb Cortex 19:2411-2427]. Our aim is now to establish a functional basis for the role of t...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/j.neuroscience.2010.06.019
更新日期:2010-09-15 00:00:00
abstract::During periods of high-frequency stimulation the maintenance of synaptic transmission depends on a continued supply of synaptic vesicles. Local recycling in the terminals ensures synaptic vesicle replenishment, but the intermediate steps are still a matter of debate. We analyzed changes in synaptic vesicle pools and e...
journal_title:Neuroscience
pub_type: 杂志文章
doi:10.1016/s0306-4522(01)00450-x
更新日期:2002-01-01 00:00:00