Identification of pathways for bipolar disorder: a meta-analysis.

abstract：IMPORTANCE:In 1939, English mathematician, geneticist, and psychiatrist Lionel Sharples Penrose hypothesized that the numbers of psychiatric hospital beds and the sizes of prison populations were inversely related; 75 years later, the question arises as to whether the hypothesis applies to recent developments in South ...

journal_title：JAMA psychiatry

authors： Mundt AP,Chow WS,Arduino M,Barrionuevo H,Fritsch R,Girala N,Minoletti A,Mitkiewicz F,Rivera G,Tavares M,Priebe S

更新日期：2015-02-01 00:00:00

abstract：:CONTEXT Clinical experience and factor analytic studies suggest that some psychiatric disorders may be more closely related to one another, as indicated by the frequency of their co-occurrence, which may have etiologic and treatment implications. OBJECTIVE To construct a virtual space of common psychiatric disorders, ...

journal_title：JAMA psychiatry

authors： Blanco C,Krueger RF,Hasin DS,Liu SM,Wang S,Kerridge BT,Saha T,Olfson M

更新日期：2013-02-01 00:00:00

abstract：IMPORTANCE:Cocaine addiction is associated with altered resting-state functional connectivity among regions of the mesocorticolimbic dopamine pathways. Methylphenidate hydrochloride, an indirect dopamine agonist, normalizes task-related regional brain activity and associated behavior in cocaine users; however, the neur...

journal_title：JAMA psychiatry

authors： Konova AB,Moeller SJ,Tomasi D,Volkow ND,Goldstein RZ

更新日期：2013-08-01 00:00:00

abstract：IMPORTANCE:Although high rates of current mental disorder are known to exist in the US Army, little is known about the proportions of these disorders that had onsets prior to enlistment. OBJECTIVE:To estimate the proportions of 30-day DSM-IV mental disorders among nondeployed US Army personnel with first onsets prior ...

journal_title：JAMA psychiatry

authors： Kessler RC,Heeringa SG,Stein MB,Colpe LJ,Fullerton CS,Hwang I,Naifeh JA,Nock MK,Petukhova M,Sampson NA,Schoenbaum M,Zaslavsky AM,Ursano RJ,Army STARRS Collaborators.

更新日期：2014-05-01 00:00:00

abstract：IMPORTANCE:Serotonin is involved in negative affect, but whether anxiety syndromes, such as social anxiety disorder (SAD), are characterized by an overactive or underactive serotonin system has not been established. Serotonin 1A autoreceptors, which inhibit serotonin synthesis and release, are downregulated in SAD, and...

journal_title：JAMA psychiatry

authors： Frick A,Åhs F,Engman J,Jonasson M,Alaie I,Björkstrand J,Frans Ö,Faria V,Linnman C,Appel L,Wahlstedt K,Lubberink M,Fredrikson M,Furmark T

更新日期：2015-08-01 00:00:00

abstract：Importance:More than 30 million people live with a stroke diagnosis worldwide. Depression after stroke is frequent, and greater knowledge of associated risk factors and outcomes is needed to understand the etiology and implications of this disabling complication. Objectives:To examine whether the incidence of and risk...

journal_title：JAMA psychiatry

authors： Jørgensen TS,Wium-Andersen IK,Wium-Andersen MK,Jørgensen MB,Prescott E,Maartensson S,Kragh-Andersen P,Osler M

更新日期：2016-10-01 00:00:00

abstract：Importance:Obesity is associated with an increased prevalence of psychiatric disorders. The association of bariatric surgery with mental health outcomes is poorly understood. Objective:To investigate the association of bariatric surgery with the incidence of outpatient, emergency department (ED), and inpatient mental ...

journal_title：JAMA psychiatry

authors： Morgan DJR,Ho KM,Platell C

更新日期：2020-01-01 00:00:00

abstract：Importance:Tobacco use disorder is associated with dysregulated neurocognitive function in the right inferior frontal gyrus (IFG)-one node in a corticothalamic inhibitory control (IC) network. Objective:To examine associations between IC neural circuitry structure and function and lapse/relapse vulnerability in 2 inde...

journal_title：JAMA psychiatry

authors： Froeliger B,McConnell PA,Bell S,Sweitzer M,Kozink RV,Eichberg C,Hallyburton M,Kaiser N,Gray KM,McClernon FJ

更新日期：2017-04-01 00:00:00

abstract：IMPORTANCE:Some, but not all, previous magnetic resonance imaging studies have indicated smaller cortical and local gray matter volumes (GMVs) in men with schizotypal personality disorder (SPD) compared with healthy control (HC) subjects. Thus, there is need for a whole-brain comparison to resolve inconsistencies and p...

journal_title：JAMA psychiatry

authors： Asami T,Whitford TJ,Bouix S,Dickey CC,Niznikiewicz M,Shenton ME,Voglmaier MM,McCarley RW

更新日期：2013-04-01 00:00:00

abstract：IMPORTANCE:Freud argued that in conversion disorder (CD) the affect attached to stressful memories is "repressed" and "converted" into physical symptoms, although this has never been subject to scientific study to our knowledge. OBJECTIVE:To examine the neural correlates of recall of life events judged to be of causal...

journal_title：JAMA psychiatry

authors： Aybek S,Nicholson TR,Zelaya F,O'Daly OG,Craig TJ,David AS,Kanaan RA

更新日期：2014-01-01 00:00:00

abstract：Importance:Deviation from normal adolescent brain development precedes manifestations of many major psychiatric symptoms. Such altered developmental trajectories in adolescents may be linked to genetic risk for psychopathology. Objective:To identify genetic variants associated with adolescent brain structure and explo...

journal_title：JAMA psychiatry

authors： Luo Q,Chen Q,Wang W,Desrivières S,Quinlan EB,Jia T,Macare C,Robert GH,Cui J,Guedj M,Palaniyappan L,Kherif F,Banaschewski T,Bokde ALW,Büchel C,Flor H,Frouin V,Garavan H,Gowland P,Heinz A,Ittermann B,Martinot JL,

更新日期：2019-04-01 00:00:00

abstract：Importance:Autism spectrum disorder (ASD) is 2 to 5 times more common in male individuals than in female individuals. While the male preponderant prevalence of ASD might partially be explained by sex differences in clinical symptoms, etiological models suggest that the biological male phenotype carries a higher intrins...

journal_title：JAMA psychiatry

authors： Ecker C,Andrews DS,Gudbrandsen CM,Marquand AF,Ginestet CE,Daly EM,Murphy CM,Lai MC,Lombardo MV,Ruigrok AN,Bullmore ET,Suckling J,Williams SC,Baron-Cohen S,Craig MC,Murphy DG,Medical Research Council Autism Imaging Multice

更新日期：2017-04-01 00:00:00

abstract：Importance:Several psychotherapy protocols have been evaluated as adjuncts to pharmacotherapy for patients with bipolar disorder, but little is known about their comparative effectiveness. Objective:To use systematic review and network meta-analysis to compare the association of using manualized psychotherapies and th...

journal_title：JAMA psychiatry

authors： Miklowitz DJ,Efthimiou O,Furukawa TA,Scott J,McLaren R,Geddes JR,Cipriani A

更新日期：2020-10-14 00:00:00

abstract：IMPORTANCE:Studies have shown that the scientific literature has overestimated the efficacy of antidepressants for depression, but other indications for these drugs have not been considered. OBJECTIVE:To examine reporting biases in double-blind, placebo-controlled trials on the pharmacologic treatment of anxiety disor...

journal_title：JAMA psychiatry

authors： Roest AM,de Jonge P,Williams CD,de Vries YA,Schoevers RA,Turner EH

更新日期：2015-05-01 00:00:00

abstract：Importance:Great interest exists in identifying methods to predict neuropsychiatric disease states and treatment outcomes from high-dimensional data, including neuroimaging and genomics data. The goal of this review is to highlight several potential problems that can arise in studies that aim to establish prediction. ...

journal_title：JAMA psychiatry

authors： Poldrack RA,Huckins G,Varoquaux G

更新日期：2020-05-01 00:00:00

abstract：IMPORTANCE:Recent estimates indicate that 6.5 million adolescents and young adults in the United States are neither in school nor working. These youth have significant mental health concerns that require intervention. OBJECTIVE:To determine whether a mental health intervention, integrated into an employment training p...

journal_title：JAMA psychiatry

authors： Tandon SD,Latimore AD,Clay E,Mitchell L,Tucker M,Sonenstein FL

更新日期：2015-01-01 00:00:00

abstract：Importance:Dysfunctional reward processing is a leading candidate mechanism for the development of certain depressive symptoms, such as anhedonia. However, to our knowledge, there has not yet been a systematic assessment of whether and to what extent depression is associated with impairments on behavioral reward-proces...

journal_title：JAMA psychiatry

authors： Halahakoon DC,Kieslich K,O'Driscoll C,Nair A,Lewis G,Roiser JP

更新日期：2020-07-29 00:00:00

abstract：Importance:Identifying genes and proteins for cognitive resilience (ie, targets that may be associated with slowing or preventing cognitive decline regardless of the presence, number, or combination of common neuropathologic conditions) provides a complementary approach to developing novel therapeutics for the treatmen...

journal_title：JAMA psychiatry

authors： Yu L,Tasaki S,Schneider JA,Arfanakis K,Duong DM,Wingo AP,Wingo TS,Kearns N,Thatcher GRJ,Seyfried NT,Levey AI,De Jager PL,Bennett DA

更新日期：2020-07-01 00:00:00

abstract：IMPORTANCE:Sedentary behaviors and physical inactivity are not only increasing worldwide but also are critical risk factors for adverse health outcomes. Yet, few studies have examined the effects of sedentary behavior on cognition or the long-term role of either behavior in early to middle adulthood. OBJECTIVE:To inve...

journal_title：JAMA psychiatry

authors： Hoang TD,Reis J,Zhu N,Jacobs DR Jr,Launer LJ,Whitmer RA,Sidney S,Yaffe K

更新日期：2016-01-01 00:00:00

abstract：IMPORTANCE:Forward models predict the sensory consequences of planned actions and permit discrimination of self- and non-self-elicited sensation; their impairment in schizophrenia is implied by an abnormality in behavioral force-matching and the flawed agency judgments characteristic of positive symptoms, including aud...

journal_title：JAMA psychiatry

authors： Shergill SS,White TP,Joyce DW,Bays PM,Wolpert DM,Frith CD

更新日期：2014-01-01 00:00:00

abstract：:In 1893 and 1896, in his fourth and fifth textbook editions, Emil Kraepelin brought together 3 syndromes to form the first and second of his 2 prequels to dementia praecox (DP), a definitive version of which he would propose in his 1899 sixth textbook edition. These syndromes, which would become hebephrenic DP, catato...

journal_title：JAMA psychiatry

authors： Kendler KS

更新日期：2020-06-10 00:00:00

abstract：IMPORTANCE:Anorexia nervosa (AN) is a serious disorder with high rates of morbidity and mortality. Family-based treatment (FBT) is an evidence-based therapy for adolescent AN, but less than half of those who receive this approach recover. Hence, it is important to identify other approaches to prevent the development of...

journal_title：JAMA psychiatry

authors： Agras WS,Lock J,Brandt H,Bryson SW,Dodge E,Halmi KA,Jo B,Johnson C,Kaye W,Wilfley D,Woodside B

更新日期：2014-11-01 00:00:00

abstract：IMPORTANCE:Cocaine dependence is a significant public health problem, yet no validated pharmacological treatment exists. The potent γ-aminobutyric acid (GABA)ergic medication vigabatrin has previously been shown to be effective in a double-blind single-site study conducted in Mexico. OBJECTIVE:To evaluate the safety a...

journal_title：JAMA psychiatry

authors： Somoza EC,Winship D,Gorodetzky CW,Lewis D,Ciraulo DA,Galloway GP,Segal SD,Sheehan M,Roache JD,Bickel WK,Jasinski D,Watson DW,Miller SR,Somoza P,Winhusen T

更新日期：2013-06-01 00:00:00

abstract：IMPORTANCE:Community functioning is a core component of the functional deficits in schizophrenia, yet little systematic research on the origins of these functional deficits has been performed. OBJECTIVES:To examine 3 key domains of community functioning--social activity, independent behavior, and functioning in school...

journal_title：JAMA psychiatry

authors： Velthorst E,Reichenberg A,Kapra O,Goldberg S,Fromer M,Fruchter E,Ginat K,de Haan L,Davidson M,Weiser M

更新日期：2016-01-01 00:00:00

abstract：IMPORTANCE:Mental health (MH) conditions are undertreated in late life. It is important to identify treatment strategies that address variability in treatment content and delivery and take individual-specific symptoms into account, particularly among low-income, community-dwelling older adults. OBJECTIVE:To evaluate p...

journal_title：JAMA psychiatry

authors： Mavandadi S,Benson A,DiFilippo S,Streim JE,Oslin D

更新日期：2015-12-01 00:00:00

abstract：Importance:Altered neurodevelopmental trajectories are thought to reflect heterogeneity in the pathophysiologic characteristics of schizophrenia, but whether neural indicators of these trajectories are associated with future psychosis is unclear. Objective:To investigate distinct neuroanatomical markers that can diffe...

journal_title：JAMA psychiatry

authors： Chung Y,Addington J,Bearden CE,Cadenhead K,Cornblatt B,Mathalon DH,McGlashan T,Perkins D,Seidman LJ,Tsuang M,Walker E,Woods SW,McEwen S,van Erp TGM,Cannon TD,North American Prodrome Longitudinal Study (NAPLS) Consortium and

更新日期：2018-09-01 00:00:00

abstract：IMPORTANCE:Depression and obesity are 2 prevalent disorders that have been repeatedly shown to be associated. However, the mechanisms and temporal sequence underlying this association are poorly understood. OBJECTIVE:To determine whether the subtypes of major depressive disorder (MDD; melancholic, atypical, combined, ...

journal_title：JAMA psychiatry

authors： Lasserre AM,Glaus J,Vandeleur CL,Marques-Vidal P,Vaucher J,Bastardot F,Waeber G,Vollenweider P,Preisig M

更新日期：2014-08-01 00:00:00

abstract：Importance:Preeclampsia during pregnancy has been linked to an increased risk of cerebral palsy in offspring. Less is known about the role of preeclampsia in other neurodevelopmental disorders. Objective:To determine the association between preeclampsia and a range of adverse neurodevelopmental outcomes in offspring a...

journal_title：JAMA psychiatry

authors： Sun BZ,Moster D,Harmon QE,Wilcox AJ

更新日期：2020-08-01 00:00:00

abstract：IMPORTANCE:Psychotic persons who are violent often explain their violence as being due to delusions. However, research has failed to confirm associations between delusions and violent behavior. OBJECTIVES:To investigate which delusional beliefs and characteristics are associated with violent behavior during a first ep...

journal_title：JAMA psychiatry

authors： Coid JW,Ullrich S,Kallis C,Keers R,Barker D,Cowden F,Stamps R

更新日期：2013-05-01 00:00:00

abstract：IMPORTANCE:Mood disorders and alcohol dependence frequently co-occur. Etiologic theories concerning the comorbidity often focus on drinking to self-medicate or cope with affective symptoms. However, there have been few, if any, prospective studies in population-based samples of alcohol self-medication of mood symptoms ...

journal_title：JAMA psychiatry

authors： Crum RM,Mojtabai R,Lazareck S,Bolton JM,Robinson J,Sareen J,Green KM,Stuart EA,La Flair L,Alvanzo AA,Storr CL

更新日期：2013-07-01 00:00:00