Role of (1,3)(1,4)-β-glucan in cell walls: interaction with cellulose.

abstract：:Synthesis of novel zwitterionic block copolypeptides, poly(N-isopropylacrylamide)-block-poly(L-glutamic acid-co-L-lysine) [PNiPAM(n)(PLG(x)-co-PLLys(y))m , where n is the number-average degree of polymerization (DP(n)) of PNiPAM block, x and y are the mole fraction of glutamic acid and lysine residues, respectively, a...

journal_title：Biomacromolecules

authors： Li J,Wang T,Wu D,Zhang X,Yan J,Du S,Guo Y,Wang J,Zhang A

更新日期：2008-10-01 00:00:00

abstract：:A novel linear multifunctional polyethylene glycol (PEG)-dexamethasone (Dex) conjugate (click PEG-Dex) was synthesized using facile Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition (a click reaction). Dex was conjugated to the click PEG via an acid-labile hydrazone bond to allow the drug release in a pathophysiologic...

journal_title：Biomacromolecules

authors： Liu XM,Quan LD,Tian J,Laquer FC,Ciborowski P,Wang D

更新日期：2010-10-11 00:00:00

abstract：:A His-tagged coiled coil stem loop peptide with stable secondary structure was designed and biosynthesized. A series of oligopeptides related to the EBV envelope glycoprotein 350/220 N-terminal nonapeptide as potential CD21 receptor-binding epitopes were engineered into the loop region of the peptide scaffold. It was ...

journal_title：Biomacromolecules

authors： Tang A,Kopecek J

更新日期：2002-05-01 00:00:00

abstract：:Peptide RATEA16 spontaneously self-assembled into higher-order nanofiber hydrogels with extremely high water content (>99.5% (wt/vol)) under physiological condition. The hydrogels could undergo pH-reversible transitions from viscous solution to elastic hydrogel and to precipitate. The supramolecular self-assembly and ...

journal_title：Biomacromolecules

authors： Zhao Y,Yokoi H,Tanaka M,Kinoshita T,Tan T

更新日期：2008-06-01 00:00:00

abstract：:This study investigated the impact of the protein adsorption mechanism(s) on the efficiency of thermally controlled cell adhesion and release from poly(N-isopropyl acrylamide) brushes. Large format polymer gradients were used to screen for grafting densities and substrate chemistries that alter both cell adhesion at 3...

journal_title：Biomacromolecules

authors： Choi S,Choi BC,Xue C,Leckband D

更新日期：2013-01-14 00:00:00

abstract：:Benefiting from their inherent localized and controlled release properties, hydrogels are ideal delivery systems for therapeutic drugs or nanoparticles. In particular, applications of hydrogels for the delivery and release of photoresponsive drugs or nanoparticles are receiving increasing attention. However, the effec...

journal_title：Biomacromolecules

authors： Xia LY,Zhang X,Cao M,Chen Z,Wu FG

更新日期：2017-10-09 00:00:00

abstract：:Nanocoating of individual mammalian cells with polymer layers has been of increasing interest in biotechnology and biomedical engineering applications. Electrostatic layer-by-layer (LbL) deposition of polyelectrolytes on negatively charged cell surfaces has been utilized for cell nanocoatings using synthetic or natura...

journal_title：Biomacromolecules

authors： Hasturk O,Sahoo JK,Kaplan DL

更新日期：2020-07-13 00:00:00

abstract：:The application of nanoparticles comprising amphiphilic block copolymers for the delivery of drugs is a subject of great interest as they hold promise for more effective and selective therapies. In order to achieve this ambition, it is of critical importance to develop our understanding of the self-assembly mechanisms...

journal_title：Biomacromolecules

authors： Ridolfo R,Arends JJ,van Hest JCM,Williams DS

更新日期：2020-06-08 00:00:00

abstract：:The islet amyloid polypeptide (IAPP) is a regulatory peptide that can aggregate into fibrillar structures associated with type 2 diabetes. In this study, the IAPP21-27 segment was modified with a biotin linker at the N-terminus (Btn-GNNFGAIL) to immobilize peptide fibrils on streptavidin-coated surfaces. Key residues ...

journal_title：Biomacromolecules

authors： John T,Bandak J,Sarveson N,Hackl C,Risselada HJ,Prager A,Elsner C,Abel B

更新日期：2020-02-10 00:00:00

abstract：:Anionic copolymer systems containing sulfated monomers have great potential for delivery of cationic therapeutics, but N-isopropylacrylamide (NIPAm) 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) copolymer nanoparticles have seen limited characterization to date with regard to physical properties relevant to load...

journal_title：Biomacromolecules

authors： Bartlett RL 2nd,Medow MR,Panitch A,Seal B

更新日期：2012-04-09 00:00:00

abstract：:Cellular uptake and intracellular targeting to specific organelles are key events in the cellular processing of nanomaterials. Herein, we perform a detailed structure-property relationship study on carboxylic acid-side-chain-bearing polyacrylates to provide design criteria for the manipulation of their cellular intera...

journal_title：Biomacromolecules

authors： Mahmoud AM,Morrow JP,Pizzi D,Azizah AM,Davis TP,Tabor RF,Kempe K

更新日期：2020-08-10 00:00:00

abstract：:A systematic study is carried out to understand how physical and covalent crosslinks affect the mechanical properties of an eight-arm poly(ethyleneglycol)-based hydrogel. Heparin and heparin-binding peptide are used as a physical crosslinker, and an enzymatically cleavable peptide with a cysteine on each end serves as...

journal_title：Biomacromolecules

authors： Jeong KJ,Panitch A

更新日期：2009-05-11 00:00:00

abstract：:Hybrid dendritic-linear block copolymers based on a 4-arm poly(ethylene glycol) (PEG) core were synthesized using an accelerated AB2/CD2 dendritic growth approach through orthogonal amine/epoxy and thiol-yne chemistries. The biological activity of these 4-arm and the corresponding 2-arm hybrid dendrimers revealed an e...

journal_title：Biomacromolecules

authors： Albertazzi L,Mickler FM,Pavan GM,Salomone F,Bardi G,Panniello M,Amir E,Kang T,Killops KL,Bräuchle C,Amir RJ,Hawker CJ

更新日期：2012-12-10 00:00:00

abstract：:The aggregation phenomena in aqueous solutions of hydrophobically modified (HM) chitosan, containing 4 mol % of n-dodecyl side chains, were studied by viscometry and fluorescence spectroscopy with pyrene as a probe. The results are compared with those for unmodified chitosan. Surprisingly, fluorescence data reveal the...

journal_title：Biomacromolecules

authors： Philippova OE,Volkov EV,Sitnikova NL,Khokhlov AR,Desbrieres J,Rinaudo M

更新日期：2001-07-01 00:00:00

abstract：:The ability to direct neurite growth into a close proximity of stimulating elements of a neural prosthesis, such as a retinal or cochlear implant (CI), may enhance device performance and overcome current spatial signal resolution barriers. In this work, spiral ganglion neurons (SGNs), which are the target neurons to b...

journal_title：Biomacromolecules

authors： Tuft BW,Zhang L,Xu L,Hangartner A,Leigh B,Hansen MR,Guymon CA

更新日期：2014-10-13 00:00:00

abstract：:The synthesis of core-shell star copolymers via living free radical polymerization provides a convenient route to three-dimensional nanostructures having a poly(ethylene glycol) outer shell, a hydrophilic inner shell bearing reactive functional groups, and a central hydrophobic core. By starting with well-defined line...

journal_title：Biomacromolecules

authors： Fukukawa K,Rossin R,Hagooly A,Pressly ED,Hunt JN,Messmore BW,Wooley KL,Welch MJ,Hawker CJ

更新日期：2008-04-01 00:00:00

abstract：:In this paper, we describe the preparation and characterization of Langmuir and Langmuir-Blodgett (LB) monolayers of the enzyme organophosphorus acid anhydrolase (OPAA). Langmuir films of OPAA were characterized on different subphases, such as phosphate, ammonium carbonate, and bis-tris-propane buffers. Monolayers at ...

journal_title：Biomacromolecules

authors： Mello SV,Mabrouki M,Cao X,Leblanc RM,Cheng TC,DeFrank JJ

更新日期：2003-07-01 00:00:00

abstract：:Biodegradable multilayered capsules encapsulating basic fibroblast growth factor (bFGF) were developed as a cytokine release carrier for drug delivery systems. The multilayered hollow capsules were fabricated via the layer-by-layer (LbL) assembly of chitosan (CT) and dextran sulfate (Dex). The bFGF was encapsulated in...

journal_title：Biomacromolecules

authors： Itoh Y,Matsusaki M,Kida T,Akashi M

更新日期：2008-08-01 00:00:00

abstract：:Herein we present a unique method of using dynamic cross-links, which are dynamic covalent bonding and ionic interaction, for the construction of injectable double-network (DN) hydrogels, with the objective of cell delivery for cartilage repair. Glycol chitosan and dibenzaldhyde capped poly(ethylene oxide) formed the ...

journal_title：Biomacromolecules

authors： Yan Y,Li M,Yang D,Wang Q,Liang F,Qu X,Qiu D,Yang Z

更新日期：2017-07-10 00:00:00

abstract：:The stability of internally cross-linked casein micelles against disruption by urea (which disrupts hydrogen bonds and hydrophobic interactions) and trisodium citrate (which sequesters micellar calcium phosphate) was investigated. Addition of urea (0-6 mol L-1) and/or citrate (0-50 mmol L-1) progressively reduced the ...

journal_title：Biomacromolecules

authors： Huppertz T,Smiddy MA,de Kruif CG

更新日期：2007-04-01 00:00:00

abstract：:The synthesis of poly(methyl methacrylate-co-methacryloxysuccinimide-graft-poly(ethylene glycol)) (PMMA-co-PMASI-g-PEG) via living free radical polymerization provides a convenient route to well-defined amphiphilic graft copolymers having a controllable number of reactive functional groups, variable length PEG grafts,...

journal_title：Biomacromolecules

authors： Pressly ED,Rossin R,Hagooly A,Fukukawa K,Messmore BW,Welch MJ,Wooley KL,Lamm MS,Hule RA,Pochan DJ,Hawker CJ

更新日期：2007-10-01 00:00:00

abstract：:Glycosaminoglycans (GAGs) and glycoproteins are vital components of the extracellular matrix, directing cell proliferation, differentiation, and migration and tissue homeostasis. Here, we demonstrate supramolecular GAG-like glycopeptide nanofibers mimicking bioactive functions of natural hyaluronic acid molecules. Sel...

journal_title：Biomacromolecules

authors： Ustun Yaylaci S,Sardan Ekiz M,Arslan E,Can N,Kilic E,Ozkan H,Orujalipoor I,Ide S,Tekinay AB,Guler MO

更新日期：2016-02-08 00:00:00

abstract：:The oxidation-responsive behaviors of OEGylated poly-L-cysteine homopolypeptides, that is, poly(L-EG(x)MA-C)n, were investigated. These poly-L-cysteine derivatives adopted mixed conformation in water, in which the β-sheet accounted for a significant proportion. Upon oxidation, the thioethers in polypeptide side chains...

journal_title：Biomacromolecules

authors： Fu X,Ma Y,Shen Y,Fu W,Li Z

更新日期：2014-03-10 00:00:00

abstract：:C13-dipeptides that did not gel on their own were found to form hydrogels when combined with mixtures (coassembly). At pH = 4.6, by mixing negatively charged C13-WD (C13-WD2- and/or C13-WD-) with C13-KW or C13-YK, where the side chain of K carried positive charge, two composite hydrogels with different mechanical prop...

journal_title：Biomacromolecules

authors： Hu T,Zhang Z,Euston SR,Geng M,Pan S

更新日期：2020-12-14 00:00:00

abstract：:Bovine serum albumin (BSA) and poly(diallyldimethylammonium chloride) (PDADMAC) spontaneously form, over a range of ionic strength I and pH, dense fluids rich in both macroions. To study their nanostructure, these coacervates were prepared at low I and high pH (strong interaction) or at high I and lower pH (weaker int...

journal_title：Biomacromolecules

authors： Bohidar H,Dubin PL,Majhi PR,Tribet C,Jaeger W

更新日期：2005-05-01 00:00:00

abstract：:To investigate the influence of surface-functionalized substrates with nanostructures on the behaviors of mesenchymal stem cells, we conjugated bone morphogenetic protein 2 (BMP2) onto TiO(2) nanotubes with different diameter sizes of 30, 60, and 100 nm for in vitro study. Polydopamine was employed as the intermediate...

journal_title：Biomacromolecules

authors： Lai M,Cai K,Zhao L,Chen X,Hou Y,Yang Z

更新日期：2011-04-11 00:00:00

abstract：:Biodegradable aliphatic polyesters such as poly(lactide) and poly(ε-caprolactone), largely used in tissue engineering applications, lack suitable functional groups and biological cues to enable interactions with cells. Because of the ubiquity of thiol groups in the biological environment and the pliability of thiol ch...

journal_title：Biomacromolecules

authors： Fuoco T,Finne-Wistrand A,Pappalardo D

更新日期：2016-04-11 00:00:00

abstract：:Polyamines are essential molecules supporting the structure, conformation, and function of nucleic acids and proteins. We studied stereoisomers of alpha,alpha'-dimethylated spermine [(R,R)-Me(2)Spm, (S,S)-Me(2)Spm, (R,S)-Me(2)Spm] for their ability to provoke DNA condensation and protect DNA from damage. (R,R)- and (R...

journal_title：Biomacromolecules

authors： Nayvelt I,Hyvönen MT,Alhonen L,Pandya I,Thomas T,Khomutov AR,Vepsäläinen J,Patel R,Keinänen TA,Thomas TJ

更新日期：2010-01-11 00:00:00

abstract：:Nanoparticles with high aspect ratios have favorable attributes for drug delivery and bioimaging applications based on their enhanced tissue penetration and tumor homing properties. Here, we investigated a novel filamentous viral nanoparticle (VNP) based on the Pepino mosaic virus (PepMV), a relative of the establishe...

journal_title：Biomacromolecules

authors： Le DHT,Méndez-López E,Wang C,Commandeur U,Aranda MA,Steinmetz NF

更新日期：2019-01-14 00:00:00

abstract：:As with many other biosourced colloids, chitin nanocrystals (ChNCs) can form liquid crystalline phases with chiral nematic ordering. In this work, we demonstrate that it is possible to finely tune the liquid crystalline behavior of aqueous ChNC suspensions finely. Such control was made possible by carefully studying h...

journal_title：Biomacromolecules

authors： Narkevicius A,Steiner LM,Parker RM,Ogawa Y,Frka-Petesic B,Vignolini S

更新日期：2019-07-08 00:00:00