Abstract:
AIM:Ketamine is one of the most commonly used sedatives for facilitating painful procedures for paediatric patients in the emergency department (ED). However, the use of ketamine is associated with a common, though not serious, adverse event usually called ketamine-associated vomiting (KAV). The purpose of this study is to evaluate the anti-emetic effect of adjunctive ondansetron in paediatric patients receiving ketamine sedation in the ED. METHODS:We conducted a prospective, randomised, open, controlled study in children from 1 to 18 years of age who had undergone intramuscular ketamine sedation in the ED. The patients were randomised into two groups: a ketamine-only group and a ketamine/ondansetron group. The patients in the first group received ketamine alone, while those in the second group received ketamine with oral ondansetron. The incidence of KAV was estimated in the ED and after discharge, and the time to resumption of a normal diet was measured after sedation. RESULTS:A total of 237 patients were analysed. The incidence of KAV was 29.7% in the ketamine-only group and 25.2% in the ketamine/ondansetron group (P = 0.47). After administration of ketamine, the mean time to resumption of a normal diet was 8 h 54 min in the ketamine-only group and 8 h 39 min in the ketamine/ondansetron group (P = 0.67). CONCLUSIONS:A relatively high rate of KAV (29.7%) was observed, and the time to resumption of a normal diet after ketamine sedation was rather long. It turned out that, however, the adjunctive administration of ondansetron did not effectively reduce the incidence of KAV.
journal_name
J Paediatr Child Healthjournal_title
Journal of paediatrics and child healthauthors
Lee JS,Jeon WC,Park EJ,Min YG,Kim GW,Jung YS,Choi SCdoi
10.1111/jpc.12515subject
Has Abstractpub_date
2014-07-01 00:00:00pages
557-61issue
7eissn
1034-4810issn
1440-1754journal_volume
50pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:To assess the prevalence of hepatitis C in 200 patients with paediatric malignancies, surviving in remission more than 5 years from diagnosis, who had received blood product transfusions before 1990 when routine screening of blood products for hepatitis C began. METHOD:The second and third generation Abbott ...
journal_title:Journal of paediatrics and child health
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abstract:AIM:A retrospective Auckland-wide (total population approximately 1.4 million) study of hospital admissions from 2007 to 2015 was conducted to assess trends in admissions for acute post-streptococcal glomerulonephritis (APSGN) in children aged 0-14 years. METHODS:International Statistical Classification of Diseases (I...
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journal_title:Journal of paediatrics and child health
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journal_title:Journal of paediatrics and child health
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abstract::The established teratogenicity of antiepileptic drugs raises important issues in women of child-bearing age. While the association between neural tube defects and antiepileptic drugs is well recognised, other congenital malformations are known to occur. We report two siblings with characteristic craniofacial features ...
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journal_title:Journal of paediatrics and child health
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doi:10.1046/j.1440-1754.2001.00695.x
更新日期:2001-08-01 00:00:00
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journal_title:Journal of paediatrics and child health
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pub_type: 杂志文章
doi:10.1111/j.1440-1754.2007.01036.x
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abstract:OBJECTIVES:To evaluate the usefulness of a microelectronic tablet-dispenser for monitoring adherence to preventive therapy for tuberculosis infection in adolescents. METHODOLOGY:Twenty-one patients with positive Mantoux tests were treated with isoniazid (INH), dispensed in a microelectronic tablet-dispenser that recor...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:
更新日期:1999-08-01 00:00:00
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journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1046/j.1440-1754.2001.00612.x
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:To document the pattern and sequelae of invasive pneumococcal infection in hospitalized children. METHODOLOGY:Retrospective review of Streptococcus pneumoniae (Sp) isolates from normally sterile sites from 1981 to 1992 at three paediatric centres in Sydney for demographic data, spectrum of disease, predispos...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章,多中心研究
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更新日期:1995-08-01 00:00:00
abstract:AIM:To describe a respiratory support programme for children at home by parents and layperson carers. METHODS:Analysis of records of children with long-term mechanical respiratory support at home. RESULTS:From 1979 to 2008 the programme managed 168 children (median age 7 years, range 3 weeks-19 years) with obstructiv...
journal_title:Journal of paediatrics and child health
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abstract:OBJECTIVES:To determine the aetiology, incidence and short-term outcomes of New Zealand children with acute kidney injury (AKI) requiring renal replacement therapy (RRT) over a 6-year period. METHODS:A retrospective chart review of all children requiring RRT for AKI from January 2001 to December 2006 at Starship Child...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1111/j.1440-1754.2008.01373.x
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journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1111/j.1440-1754.2010.01932.x
更新日期:2012-03-01 00:00:00
abstract:AIM:To determine health-care-seeking behaviour for childhood illnesses in a resource-poor setting. METHOD:Cross-sectional survey was conducted in the children emergency room in a Nigerian tertiary hospital. Socio-demographic data and details of the place and type of care given to ill children before presentation in th...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1111/j.1440-1754.2009.01677.x
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journal_title:Journal of paediatrics and child health
pub_type: 历史文章,杂志文章
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journal_title:Journal of paediatrics and child health
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journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1111/j.1440-1754.2010.01714.x
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:It was shown that oxygen-derived free radicals, and particularly the superoxide anion, are intermediaries in the formation and activation of osteoclasts. Many antioxidant defence systems depend on micronutrients or are micronutrients themselves. Oxidative stress might be related to bone indices in newborn in...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
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更新日期:2007-10-01 00:00:00
abstract:AIM:Despite targeting newborns at risk of hypoglycaemia based on clinical characteristics, blood glucose measured at 1 and 4 h of age is frequently normal. Identification of at-risk newborns at the greatest risk of hypoglycaemia would allow more targeted, earlier intervention. We aimed to determine the ability of calcu...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1111/jpc.14473
更新日期:2019-12-01 00:00:00
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journal_title:Journal of paediatrics and child health
pub_type: 杂志文章,评审
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更新日期:2020-04-01 00:00:00
abstract::Pyridoxine dependency is a rare autosomal-recessive disorder causing intractable seizures in neonates and infants. Life-long therapy with pyridoxine is required for prevention of seizure recurrence and for an optimum intellectual outcome. With the availability of newer biochemical confirmatory tests, the conventional ...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1111/j.1440-1754.2007.01142.x
更新日期:2007-07-01 00:00:00
abstract::The busy clinician is constantly faced with clinical questions regarding patient care. It is easy to feel overwhelmed by the large amount of health information available electronically. This article offers one easy approach for searching the electronic database. It is intended for the busy clinician who is unsure how ...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1111/j.1440-1754.2012.02503.x
更新日期:2012-12-01 00:00:00
abstract::Contemporary paediatric practices of Australian Aboriginal men and women, in more than 100 Aboriginal Language Groups, comprise a living discipline whose origins predate Western medicine by tens of millennia. The history of paediatrics acknowledges this surviving continuum of the world's oldest child-care practices. B...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1111/j.1440-1754.2005.00612.x
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVES:To compare the neurobehavioural outcome of children aged 6-12 years with severe closed head injury [sCHI] (coma > 24 h), mild-to-moderate head injury [mCHI] (coma < 6 h) and orthopaedic controls. METHODS:Twenty-nine children in each group, matched for age, sex and ethnicity, were assessed using the Glasgow ...
journal_title:Journal of paediatrics and child health
pub_type: 杂志文章
doi:10.1046/j.1440-1754.1998.00239.x
更新日期:1998-08-01 00:00:00