Comparative genomics of the Bifidobacterium breve taxon.

abstract：BACKGROUND:Ammonia is one of the most common toxicological environment factors affecting shrimp health. Although ammonia tolerance in shrimp is closely related to successful industrial production, few genetic studies of this trait are available. RESULTS:In this study, we constructed a high-density genetic map of the P...

journal_title：BMC genomics

authors： Zeng D,Yang C,Li Q,Zhu W,Chen X,Peng M,Chen X,Lin Y,Wang H,Liu H,Liang J,Liu Q,Zhao Y

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:Cotton (Gossypium spp.) is the most important natural fiber crop worldwide, and cottonseed oil is its most important byproduct. Phospholipid: diacylglycerol acyltransferase (PDAT) is important in TAG biosynthesis, as it catalyzes the transfer of a fatty acyl moiety from the sn-2 position of a phospholipid to...

journal_title：BMC genomics

authors： Zang X,Geng X,Ma L,Wang N,Pei W,Wu M,Zhang J,Yu J

更新日期：2019-05-22 00:00:00

abstract：BACKGROUND:The problem of supervised DNA sequence classification arises in several fields of computational molecular biology. Although this problem has been extensively studied, it is still computationally challenging due to size of the datasets that modern sequencing technologies can produce. RESULTS:We introduce CLA...

journal_title：BMC genomics

authors： Ounit R,Wanamaker S,Close TJ,Lonardi S

更新日期：2015-03-25 00:00:00

abstract：BACKGROUND:Chlamydomonas reinhardtii is the model organism that serves as a reference for studies in algal genomics and physiology. It is of special interest in the study of the evolution of regulatory pathways from algae to higher plants. Additionally, it has recently gained attention as a potential source for bio-fue...

journal_title：BMC genomics

authors： Romero-Campero FJ,Perez-Hurtado I,Lucas-Reina E,Romero JM,Valverde F

更新日期：2016-03-12 00:00:00

abstract：BACKGROUND:Several methods have recently been developed to identify regions of the genome that have been exposed to strong selection. However, recent theoretical and empirical work suggests that polygenic models are required to identify the genomic regions that are more moderately responding to ongoing selection on com...

journal_title：BMC genomics

authors： Decker JE,Vasco DA,McKay SD,McClure MC,Rolf MM,Kim J,Northcutt SL,Bauck S,Woodward BW,Schnabel RD,Taylor JF

更新日期：2012-11-09 00:00:00

abstract：BACKGROUND:The Per-Arnt-Sim (PAS) domain represents a ubiquitous structural fold that is involved in bacterial sensing and adaptation systems, including several virulence related functions. Although PAS domains and the subclass of PhoQ-DcuS-CitA (PDC) domains have a common structure, there is limited amino acid sequenc...

journal_title：BMC genomics

authors： Shah N,Gaupp R,Moriyama H,Eskridge KM,Moriyama EN,Somerville GA

更新日期：2013-07-31 00:00:00

abstract：BACKGROUND:Fragile sites are the chromosomal regions that are susceptible to breakage, and their frequency varies among the human population. Based on the frequency of fragile site induction, they are categorized as common and rare fragile sites. Common fragile sites are sensitive to replication stress and often rearra...

journal_title：BMC genomics

authors： Kumar R,Nagpal G,Kumar V,Usmani SS,Agrawal P,Raghava GPS

更新日期：2019-04-18 00:00:00

abstract：BACKGROUND:Pseudomonas aeruginosa is an opportunistic pathogen with a high incidence of hospital infections that represents a threat to immune compromised patients. Genomic studies have shown that, in contrast to other pathogenic bacteria, clinical and environmental isolates do not show particular genomic differences. ...

journal_title：BMC genomics

authors： Grosso-Becerra MV,Santos-Medellín C,González-Valdez A,Méndez JL,Delgado G,Morales-Espinosa R,Servín-González L,Alcaraz LD,Soberón-Chávez G

更新日期：2014-04-28 00:00:00

abstract：BACKGROUND:Roche 454 pyrosequencing has become a method of choice for generating transcriptome data from non-model organisms. Once the tens to hundreds of thousands of short (250-450 base) reads have been produced, it is important to correctly assemble these to estimate the sequence of all the transcripts. Most transcr...

journal_title：BMC genomics

authors： Kumar S,Blaxter ML

更新日期：2010-10-16 00:00:00

abstract：BACKGROUND:Marek's disease (MD) is a lymphoproliferative disease in chickens caused by Marek's disease virus (MDV) and characterized by T cell lymphoma and infiltration of lymphoid cells into various organs such as liver, spleen, peripheral nerves and muscle. Resistance to MD and disease risk have long been thought to ...

journal_title：BMC genomics

authors： Yu Y,Luo J,Mitra A,Chang S,Tian F,Zhang H,Yuan P,Zhou H,Song J

更新日期：2011-10-12 00:00:00

abstract：:The Avian Genomics Conference and Gene Ontology Annotation Workshop brought together researchers and students from around the world to present their latest research addressing the delivery of value from the billions of base-pairs of Archosaur sequence that have become available in the last few years. This editorial de...

journal_title：BMC genomics

authors： Bridges SM,Burgess SC,McCarthy FM

更新日期：2009-07-14 00:00:00

abstract：BACKGROUND:Dimethylsulfoniopropionate (DMSP) is a small sulphur compound which is produced in prodigious amounts in the oceans and plays a pivotal role in the marine sulfur cycle. Until recently, DMSP was believed to be synthesized exclusively by photosynthetic organisms; however we now know that corals and specific ba...

journal_title：BMC genomics

authors： Aguilar C,Raina JB,Motti CA,Fôret S,Hayward DC,Lapeyre B,Bourne DG,Miller DJ

更新日期：2017-08-14 00:00:00

abstract：BACKGROUND:Compromised intestinal barrier (CIB) has been associated with many enteropathies, including colorectal cancer (CRC) and inflammatory bowel disease (IBD). We hypothesized that CIB could lead to increased host-derived contents including epithelial cells into the gut, change its physio-metabolic properties, and...

journal_title：BMC genomics

authors： Jiang P,Lai S,Wu S,Zhao XM,Chen WH

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:Mitochondrial genomes comprise a small but critical component of the total DNA in eukaryotic organisms. They encode several key proteins for the cell's major energy producing apparatus, the mitochondrial respiratory chain. Additionally, their nucleotide and amino acid sequences are of great utility as marker...

journal_title：BMC genomics

authors： Lloyd RE,Foster PG,Guille M,Littlewood DT

更新日期：2012-09-19 00:00:00

abstract：BACKGROUND:The transcriptome of the fruit pulp of the sweet orange variety Anliu (WT) and that of its red fleshed mutant Hong Anliu (MT) were compared to understand the dynamics and differential expression of genes expressed during fruit development and ripening. RESULTS:The transcriptomes of WT and MT were sampled at...

journal_title：BMC genomics

authors： Yu K,Xu Q,Da X,Guo F,Ding Y,Deng X

更新日期：2012-01-10 00:00:00

abstract：BACKGROUND:Matrix attachment regions (MAR) are the sites on genomic DNA that interact with the nuclear matrix. There is increasing evidence for the involvement of MAR in regulation of gene expression. The unsuitability of experimental detection of MAR for genome-wide analyses has led to the development of computational...

journal_title：BMC genomics

authors： Anthony A,Blaxter M

更新日期：2007-11-15 00:00:00

abstract：BACKGROUND:Atlantic salmon have been subject to domestication for approximately ten generations, beginning in the early 1970s. This process of artificial selection will have created various genetic differences between wild and farmed stocks. Each year, hundreds of thousands of farmed fish escape into the wild. These es...

journal_title：BMC genomics

authors： Bicskei B,Bron JE,Glover KA,Taggart JB

更新日期：2014-10-09 00:00:00

abstract：BACKGROUND:Research on the aryl hydrocarbon receptor (AHR) has largely focused on variations in toxic outcomes resulting from its activation by halogenated aromatic hydrocarbons. But the AHR also plays key roles in regulating pathways critical for development, and after decades of research the mechanisms underlying phy...

journal_title：BMC genomics

authors： Sun RX,Chong LC,Simmons TT,Houlahan KE,Prokopec SD,Watson JD,Moffat ID,Lensu S,Lindén J,P'ng C,Okey AB,Pohjanvirta R,Boutros PC

更新日期：2014-12-03 00:00:00

abstract：BACKGROUND:Microarray data analysts commonly filter out genes based on a number of ad hoc criteria prior to any high-level statistical analysis. Such ad hoc approaches could lead to conflicting conclusions with no clear guidance as to which method is most likely to be reproducible. Furthermore, the number of tests perf...

journal_title：BMC genomics

authors： Hu P,Beyene J,Greenwood CM

更新日期：2006-02-22 00:00:00

abstract：BACKGROUND:As an important nosocomial pathogen, Enterococcus faecium has received increasing attention in recent years. However, a large number of studies have focused on the hospital-associated isolates and ignored isolates originated from the natural environments. RESULTS:In this study, comparative genomic analysis ...

journal_title：BMC genomics

authors： Zhong Z,Kwok LY,Hou Q,Sun Y,Li W,Zhang H,Sun Z

更新日期：2019-07-22 00:00:00

abstract：BACKGROUND:As consumers continue to request food products that have health advantages, it will be important for the livestock industry to supply a product that meet these demands. One such nutrient is fatty acids, which have been implicated as playing a role in cardiovascular disease. Therefore, the objective of this s...

journal_title：BMC genomics

authors： Saatchi M,Garrick DJ,Tait RG Jr,Mayes MS,Drewnoski M,Schoonmaker J,Diaz C,Beitz DC,Reecy JM

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Aspartic proteases are known to play an important role in the biology of nematode parasitism. This role is best characterised in blood-feeding nematodes, where they digest haemoglobin, but they are also likely to play important roles in the biology of nematode parasites that do not feed on blood. In the pres...

journal_title：BMC genomics

authors： Mello LV,O'Meara H,Rigden DJ,Paterson S

更新日期：2009-12-16 00:00:00

abstract：BACKGROUND:A major goal in the post-genomic era is to identify and characterise disease susceptibility genes and to apply this knowledge to disease prevention and treatment. Rodents and humans have remarkably similar genomes and share closely related biochemical, physiological and pathological pathways. In this work we...

journal_title：BMC genomics

authors： Silva DG,Schönbach C,Brusic V,Socha LA,Nagashima T,Petrovsky N

更新日期：2004-04-29 00:00:00

abstract：BACKGROUND:Thousands of intragenic long interspersed element 1 sequences (LINE-1 elements or L1s) reside within genes. These intragenic L1 sequences are conserved and regulate the expression of their host genes. When L1 methylation is decreased, either through chemical induction or in cancer, the intragenic L1 transcri...

journal_title：BMC genomics

authors： Wanichnopparat W,Suwanwongse K,Pin-On P,Aporntewan C,Mutirangura A

更新日期：2013-03-27 00:00:00

abstract：BACKGROUND:Intensive research based on the inverse expression relationship has been undertaken to discover the miRNA-mRNA regulatory modules involved in the infection of Hepatitis C virus (HCV), the leading cause of chronic liver diseases. However, biological studies in other fields have found that inverse expression r...

journal_title：BMC genomics

authors： Song R,Liu Q,Liu T,Li J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The Lundehund is a highly specialized breed characterized by a unique flexibility of the joints and polydactyly in all four limbs. The extremely small population size and high inbreeding has promoted a high frequency of diseased dogs affected by the Lundehund syndrome (LS), a severe gastro-enteropathic disea...

journal_title：BMC genomics

authors： Metzger J,Pfahler S,Distl O

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Bacteriophages are the most abundant and diverse entities in the biosphere, and this diversity is driven by constant predator-prey evolutionary dynamics and horizontal gene transfer. Phage genome sequences are under-sampled and therefore present an untapped and uncharacterized source of genetic diversity, ty...

journal_title：BMC genomics

authors： Oliveira H,Sampaio M,Melo LDR,Dias O,Pope WH,Hatfull GF,Azeredo J

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:Laboratory evolution is an important tool for developing robust yeast strains for bioethanol production since the biological basis behind combined tolerance requires complex alterations whose proper regulation is difficult to achieve by rational metabolic engineering. Previously, we reported on the evolved i...

journal_title：BMC genomics

authors： Wallace-Salinas V,Brink DP,Ahrén D,Gorwa-Grauslund MF

更新日期：2015-07-09 00:00:00

abstract：BACKGROUND:Genetic diversity within a species reflects population evolution, ecology, and ability to adapt. Genome-wide population surveys of both natural and introduced populations provide insights into genetic diversity, the evolutionary processes and the genetic basis underlying local adaptation. Grass carp is the m...

journal_title：BMC genomics

authors： Shen Y,Wang L,Fu J,Xu X,Yue GH,Li J

更新日期：2019-06-07 00:00:00

abstract：BACKGROUND:The transformation of a developing epithelium into an adult structure is a complex process, which often involves coordinated changes in cell proliferation, metabolism, adhesion, and shape. To identify genetic mechanisms that control epithelial differentiation, we analyzed the temporal patterns of gene expres...

journal_title：BMC genomics

authors： O'Keefe DD,Thomas SR,Bolin K,Griggs E,Edgar BA,Buttitta LA

更新日期：2012-09-20 00:00:00