Abstract:
OBJECTIVES:Rule induction is one of the major methods of machine learning. Rule-based models can be easily read and interpreted by humans, that makes them particularly useful in survival studies as they can help clinicians to better understand analysed data and make informed decisions about patient treatment. Although of such usefulness, there is still a little research on rule learning in survival analysis. In this paper we take a step towards rule-based analysis of survival data. METHODS:We investigate so-called covering or separate-and-conquer method of rule induction in combination with a weighting scheme for handling censored observations. We also focus on rule quality measures being one of the key elements differentiating particular implementations of separate-and-conquer rule induction algorithms. We examine 15 rule quality measures guiding rule induction process and reflecting a wide range of different rule learning heuristics. RESULTS:The algorithm is extensively tested on a collection of 20 real survival datasets and compared with the state-of-the-art survival trees and random survival forests algorithms. Most of the rule quality measures outperform Kaplan-Meier estimate and perform at least equally well as tree-based algorithms. CONCLUSIONS:Separate-and-conquer rule induction in combination with weighting scheme is an effective technique for building rule-based models of survival data which, according to predictive accuracy, are competitive with tree-based representations.
journal_name
Methods Inf Medjournal_title
Methods of information in medicineauthors
Wróbel Ł,Sikora Mdoi
10.3414/ME13-01-0046subject
Has Abstractpub_date
2014-01-01 00:00:00pages
137-48issue
2eissn
0026-1270issn
2511-705Xpii
13-01-0046journal_volume
53pub_type
杂志文章abstract:OBJECTIVES:Data collected within the German nosocomial infection surveillance system KISS are recommended as reference data for judging nosocomial infection rates in German intensive care units (ICUs). It is unknown whether the KISS data tend to under- or overestimate the true infection incidence rates. In this article...
journal_title:Methods of information in medicine
pub_type: 杂志文章,多中心研究
doi:
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:IMIA, the International Medical Informatics Association, has adopted the IMIA Strategic Plan, "Towards IMIA 2015". In order to turn the vision into reality, we invite all members of IMIA, and others with an interest in our work, to engage in activities designed to achieve the key strategic goals of the plan. ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:To assess the effects of a CPOE system on inter-professional workflow in the medication process. METHODS:Twenty-three semi-structured interviews with physicians, nurses, and pharmacists were conducted in a Dutch academic hospital. In addition, the handwritten and system-generated documents used daily were c...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME0631
更新日期:2010-01-01 00:00:00
abstract::Appropriateness and necessity research of various procedures in medicine may be the most complex field of innovation in healthcare and technology assessment. Nevertheless, the appropriateness of the indication of any medical intervention is probably more important than the outcome since even ideal quality components o...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::Four tabular and two graphical techniques for the presentation of laboratory test results were evaluated in a reaction time experiment with 25 volunteers. Artificial variables and values were used to represent sets of 12 laboratory tests to eliminate the possible effects of clinical experience. Analyses focused on fou...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:The exchange of medical data from research and clinical routine across institutional borders is essential to establish an integrated healthcare platform. In this project we want to realize the standardized exchange of medical data between different healthcare institutions to implement an integrated and inter...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::Three ways are proposed to help the occupational physician in constructing a worker's job history or Curriculum Laboris (CL) with a PC. The quality and, therefore, the usefulness of any job history is greatly conditioned by the method and quality of data collection. The Curriculum Laboris method explained in a previou...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::The graduates and students of the School of Health Information Science (HIS) at the University of Victoria (UVic) have pioneered the Canadian sphere in health informatics since 1982. After six years of growth this co-operative education program has matured and establishment of a research base and graduate school has b...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract:OBJECTIVES:To investigate the nonlinear characteristics of visual evoked potentials (VEPs), and their correlation with the visual responses on parvocellular and magnocellular pathways. First and second-order kernels of the VEPs elicited by several checkerboard patterns were estimated, and their relations to the visual ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:This article is part of the Focus Theme of Methods of Information in Medicine on "Big Data and Analytics in Healthcare". BACKGROUND:Hospital readmissions raise healthcare costs and cause significant distress to providers and patients. It is, therefore, of great interest to healthcare organizations to pred...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME14-02-0017
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The information present in Hospital Information Systems (HIS) is heterogeneous and is used primarily by health practitioners to support and improve patient care. Conducting clinical research, data analyses or knowledge discovery projects using electronic patient data in secondary care centres relies on accur...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME10-01-0069
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:In this study, we evaluated the internal validity of EPICON, an application for grouping ICPC-coded diagnoses from electronic medical records into episodes of care. These episodes are used to estimate morbidity rates in general practice. METHODS:Morbidity rates based on EPICON were compared to a gold standa...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:Ventricular tachycardia (VT) provoking sudden cardiac death (SCD) are a major cause of mortality in the developed countries. The most efficient therapy for SCD prevention are implantable cardioverter defibrillators (ICD). In this study heart rate variability (HRV) measures were analyzed for short-term foreca...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:Our objective was to design and develop a mobile clinical decision support system for emergency triage of different acute pain presentations. The system should interact with existing hospital information systems, run on mobile computing devices (handheld computers) and be suitable for operation in weak-conne...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Many clinics are interested to use software packages in daily practice, but lack of integration of such packages seriously limits their scope. In practice this often entails switching between programs and interrupting the run of an individual program. A multi-task approach would not solve this problem as it would not ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract:OBJECTIVES:To discuss the advantages and disadvantages of an interfaced approach to clinical information systems architecture. METHODS:After many years of internally building almost all components of a hospital clinical information system (HELP) at Intermountain Health Care, we changed our architectural approach as we...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:This paper addresses the design of a platform for the management of medical decision data in the ICU. Whenever new medical data from laboratories or monitors is available or at fixed times, the appropriate medical support services are activated and generate a medical alert or suggestion to the bedside termin...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/me0480
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:The availability of large amounts of data in heterogeneous formats and the rapid progress in fields such as computer based drug design, medical imaging and medical simulations have lead to a growing demand for large computational power and easy accessibility to heterogeneous data sources. OBJECTIVES:The goa...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:The National Cancer Institute (NCI) has developed the Common Data Elements (CDE) to serve as a controlled vocabulary of data descriptors for cancer research, to facilitate data interchange and inter-operability between cancer research centers. We evaluated CDE's structure to see whether it could represent th...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract::BRAINDEX (Brain-Death Expert System) is an interactive, knowledge-based expert system offering support to physicians in decision making concerning brain death. The physician is given the possibility of communicating in almost natural language and, therefore, in terms with which he is familiar. This updated version of ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract:INTRODUCTION:This article is part of the Focus Theme of METHODS of Information in Medicine on "Managing Interoperability and Complexity in Health Systems". OBJECTIVES:In previous work, we have defined methods for the extraction of lexical patterns from labels as an initial step towards semi-automatic ontology enrichme...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME13-02-0026
更新日期:2015-01-01 00:00:00
abstract::A Bonhoeffer-van der Pol equation with a stable limit cycle is proposed as a model of the pacemaker in the sino-atrial node to explain heart rate regulation. Standard tools, such as the phase transition curve in nonlinear dynamic system theory, are used to analyze the model and results are compared with other studies ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::In this study, we attempted to discriminate the acceleration signal for horizontal level and stairway walking using wavelet-based fractal analysis method. The acceleration signal was measured close to the center of gravity of the body, while the subjects walked continuously in the corridor and up and down the stairs. ...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract:OBJECTIVE:Introducing the Special Topic of Methods of Information in Medicine on pervasive healthcare, with selected papers from the Pervasive Healthcare Conference at Tampere, Finland, January 30 to February 1, 2008. METHODS:Describing pervasive healthcare as field. Reporting about the content of the selected papers ...
journal_title:Methods of information in medicine
pub_type: 社论
doi:
更新日期:2008-01-01 00:00:00
abstract::To display multidimensional laboratory measurements, Hoeke et al. (1991) proposed a technique that uses plotting axes radiating from a point, assigns each test to a separate axis, and links the test results with line segments. A special nonlinear scaling ensures that a patient whose results all fall in the normal rang...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVES:The main objective is to show current topics and future trends in the field of medical signal processing which are derived from current research concepts. Signal processing as an integrative concept within the scope of medical informatics is demonstrated. METHODS:For all examples time-variant multivariate a...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::This editorial is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Evidence-based Health informatics: How do we know what we know?", written by Elske Ammenwerth [1]. Health informatics uses and applications have crept up on health systems over half a century, starting as simple a...
journal_title:Methods of information in medicine
pub_type: 评论,社论
doi:10.3414/ME14-10-0139
更新日期:2015-01-01 00:00:00
abstract::In this paper we describe LIED (Liver: Information, Education and Diagnosis), a diagnostic expert system devoted to medical education in the field of hepatology. LIED combines the facilities of a traditional expert system for clinical diagnosis with several modules designed for educational purposes. The goal of such m...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract:INTRODUCTION:This article is part of the focus theme of Methods of Information in Medicine on "Pervasive Intelligent Technologies for Health". BACKGROUND:This paper addresses the evaluation with hospital staff of an in-patient environment that supports patients, family, nursing staff and medical specialists during the...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:10.3414/ME13-02-0032
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Cerebral ventricular volume has the potential to become an important parameter in quantitative neurological diagnosis. However, no accepted methodology for routine clinical use exists to date. We sought a robust, reproducible, and fast technique to evaluate cerebral ventricular volume in young children. MET...
journal_title:Methods of information in medicine
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00