Which cardiovascular risk factors are associated with cardiovascular disease and predict future events in advanced age in New Zealand?

Abstract:

AIM:To examine the relationships between cardiovascular risk factors, cardiovascular health at baseline, and cardiovascular disease (CVD) events 28 months later, in advanced age. METHODS:108 adults in advanced age were recruited. Data were collected through a standardised questionnaire including a measure of physical activity, comprehensive physical assessment and fasting blood samples. CVD events at follow-up were ascertained from hospital records. RESULTS:Sixty-seven per cent of participants had CVD at baseline. Physical activity (OR (95% CI): 0.99 (0.98-1.0); P = 0.04) and high-density lipoprotein (HDL) (OR (95% CI): 0.3 (0.09-1.0); P = 0.046) were independently associated with CVD. The 28-month incidence rate of CVD was 6 cases/100 person-years. Baseline diastolic BP (OR (95% CI): 0.9 (0.9-1.0); P = 0.03) and waist circumference (OR (95% CI): 1.06 (1.01-1.1); P = 0.01) were independently associated with subsequent CVD events at follow-up. CONCLUSION:Physical activity and HDL levels were inversely associated with CVD at baseline but did not predict future CVD events. CVD in advanced age warrants further investigation.

journal_name

Australas J Ageing

authors

Teh RO,Kerse NM,Robinson EM,Doughty RN,Whalley GA

doi

10.1111/j.1741-6612.2012.00626.x

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

14-21

issue

1

eissn

1440-6381

issn

1741-6612

journal_volume

33

pub_type

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