Abstract:
BACKGROUND:Compared to volume/circumference measurements to diagnose lymphedema, thickening and disturbance of echogenicity of cutis and subcutis associated with the development of lymphedema is measured directly by ultrasonography. The aim of the present study was to investigate the evolution of thickness and echogenicity of cutis and subcutis of the lower and upper arm after axillary dissection for breast cancer and compare patients with and without arm lymphedema. METHODS AND RESULTS:Immediately after the surgery and at 6 and 12 months post-surgery, 42 patients received an ultrasonography of both arms, at the wrist, ventral and dorsal side of the lower arm, and biceps and triceps side of the upper arm. Thickness and echogenicity of cutis and subcutis were determined. Lymphedema was defined as 5.0% or more increase compare to the preoperative value. Eighteen patients had developed lymphedema of the lower arm, and 24 patients of the upper arm. Thickness of the cutis decreased significantly during the postoperative period on the healthy and affected side as well. The difference of cutis thickness between affected and healthy side increased postoperatively in patients with lymphedema and decreased in patients without lymphedema at the wrist and dorsal side of the lower arm. Patients with lymphedema had more frequent disturbance of echogenicity of the cutis at all measurement points. In exception of the triceps, thickness and echogenicity of the subcutis is less obvious disturbed. Sensitivity to detect arm lymphedema by ultrasonography was acceptable for increased subcutis thickness at the ventral lower arm and triceps and disturbed cutis echogenicity at the wrist (67%-100%). Sensitivity for the other measurements was bad. Specificity was for all measurements acceptable (59%-100%). CONCLUSION:Ultrasonography may be useful to diagnose lymphedema developing after axillary dissection for breast cancer. However, it cannot be used as a separate diagnostic test for lymphedema.
journal_name
Lymphat Res Bioljournal_title
Lymphatic research and biologyauthors
Devoogdt N,Pans S,De Groef A,Geraerts I,Christiaens MR,Neven P,Vergote I,Van Kampen Mdoi
10.1089/lrb.2013.0028subject
Has Abstractpub_date
2014-03-01 00:00:00pages
23-31issue
1eissn
1539-6851issn
1557-8585journal_volume
12pub_type
杂志文章abstract:BACKGROUND:Lymphedema of limbs affects a large mass of tissues. Pathological changes develop in skin and subcutaneous tissue. Bacterial retention in edema fluid is followed by chronic inflammatory reaction. The question arises whether the chronic processes affecting a large mass of limb tissues are reflected in the ser...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
doi:10.1089/lrb.2017.0003
更新日期:2017-09-01 00:00:00
abstract:: Background: Multiple staging systems for classifying the severity of lymphedema exist. The International Society of Lymphology (ISL) stage is considered standard for clinical reporting, but the relationship between clinical and functional/imaging stage remains poorly defin...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
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abstract::Pediatric hepatic angiosarcoma is a very rare malignant vascular tumor. A few cases have shown pediatric hepatic angiosarcoma occurring on a background of preexisting vascular lesions. We report the case of a newborn girl who presented extensive limbs and upper trunk cutaneous mixed vascular malformations at birth. Th...
journal_title:Lymphatic research and biology
pub_type: 杂志文章
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journal_title:Lymphatic research and biology
pub_type: 杂志文章,多中心研究
doi:10.1089/lrb.2017.0048
更新日期:2018-06-01 00:00:00
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journal_title:Lymphatic research and biology
pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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journal_title:Lymphatic research and biology
pub_type: 杂志文章
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journal_title:Lymphatic research and biology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Lymphatic research and biology
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journal_title:Lymphatic research and biology
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journal_title:Lymphatic research and biology
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journal_title:Lymphatic research and biology
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journal_title:Lymphatic research and biology
pub_type: 临床试验,杂志文章,随机对照试验
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doi:10.1089/lrb.2006.4.3
更新日期:2006-04-01 00:00:00
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journal_title:Lymphatic research and biology
pub_type: 杂志文章,评审
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journal_title:Lymphatic research and biology
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更新日期:2018-06-01 00:00:00
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journal_title:Lymphatic research and biology
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journal_title:Lymphatic research and biology
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journal_title:Lymphatic research and biology
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journal_title:Lymphatic research and biology
pub_type: 杂志文章
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pub_type: 杂志文章
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