Abstract：
PURPOSE:The potential association between endometriosis and coffee/caffeine consumption has been analysed in several epidemiological studies. In order to establish whether caffeine influences the risk of endometriosis, we provide to summarize the evidence from published studies on this issue. METHODS:We performed a meta-analysis of epidemiological studies published up to January 2013. We computed summary relative risks (RR) of endometriosis for any, high and low versus no coffee/caffeine consumption. RESULTS:We identified a total eight studies, six case-control and two cohort studies, including a total of 1,407 women with endometriosis. The summary RR for any versus non-consumption were 1.26 [95% confidence interval (CI) 0.95-1.66] for caffeine and 1.13 (95% CI 0.46-2.76) for coffee consumption; the overall estimate was 1.18 (95% CI 0.92-1.49). The summary RR were 1.09 (95% CI 0.84-1.42) and 1.09 (95% CI 0.89-1.33) for high and low caffeine consumption as compared to no consumption, respectively. CONCLUSION:The present meta-analysis provided no evidence for an association between coffee/caffeine consumption and the risk of endometriosis. Coffee/caffeine consumption, as currently used in diet, does not carry a health risk.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Chiaffarino F,Bravi F,Cipriani S,Parazzini F,Ricci E,Viganò P,La Vecchia Cdoi
10.1007/s00394-014-0662-7subject
Has Abstractpub_date
2014-10-01 00:00:00pages
1573-9issue
7eissn
1436-6207issn
1436-6215journal_volume
53pub_type
杂志文章,meta分析abstract：PURPOSE:Nonalcoholic fatty liver disease (NAFLD) is currently the leading cause of chronic liver disease in developing countries. The pathogenesis is complex, and there is currently no effective treatment. Betaine is an essential intermediate in choline catabolism and an important component of the methionine cycle. Bet...
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pub_type： 临床试验,杂志文章
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pub_type： 临床试验,杂志文章,随机对照试验
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pub_type： 杂志文章,随机对照试验
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更新日期：2008-12-01 00:00:00
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