Clinical features and glaucoma according to optic disc size in a South Korean population: the Namil study.

Abstract:

PURPOSE:To assess the proportion of glaucomatous eyes based on the association between optic disc (OD) size and its clinical determinants in the resident population of Namil-myon, Central South Korea. METHODS:Of the 1,532 participants in the Namil study, we included 1,410 Koreans (2,734 eyes) with legible fundus photographs in this study. Following the estimation of OD size on the photographs using Image J software, we corrected for image magnification. Associations between the clinical features, such as age, sex, axial length (AL), spherical equivalent (SE), and central corneal thickness, and the estimated OD size were assessed for individual eyes. After adjusting for the influencing factors, the proportion of glaucoma was compared among three categories of measured OD size (small, medium, and large OD groups). RESULTS:After adjusting for the potential confounders using a linear mixed model, age, sex, AL, and SE were correlated with the OD size estimates (P = 0.003, P = 0.029, P < 0.001, and P < 0.001, respectively). The percentage of glaucomatous eyes was 3.77 % in the small disc group, which was higher than in the other groups (P = 0.054). In particular, normal tension glaucoma (NTG) was statistically significantly more frequent in this group (odds ratio = 1.86, P = 0.042). CONCLUSIONS:These results suggest that clinical features such as age, sex, AL, and SE might need to be considered for an accurate evaluation of the OD. In addition, in individuals with a small OD, the presence of NTG must be carefully investigated in the South Korea population.

journal_name

Jpn J Ophthalmol

authors

Kang NH,Jun RM,Choi KR,Namil Study group, Korean Glaucoma Society.

doi

10.1007/s10384-014-0303-y

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

205-11

issue

2

eissn

0021-5155

issn

1613-2246

journal_volume

58

pub_type

杂志文章
  • Eye wall resection in the management of uveal neoplasms.

    abstract::Management of intraocular tumors, specifically uveal melanoma, is a matter of controversy. The treatment of these ocular neoplasms varies from observation to enucleation, irradiation (cobalt plaque and proton-helium particle) and eye wall resection. Over the last 18 years, we have developed two techniques for surgical...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Peyman GA,Gremillion CM

    更新日期:1989-01-01 00:00:00

  • Novel XLRS1 gene mutations cause X-linked juvenile retinoschisis in Chinese families.

    abstract:PURPOSE:To investigate various XLRS1 (RS1) gene mutations in Chinese families with X-linked juvenile retinoschisis (XLRS or RS). METHODS:Genomic DNA was isolated from leukocytes of 29 male patients with X-linked juvenile retinoschisis, 38 female carriers, and 100 normal controls. All 6 exons of the RS1 gene were ampli...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-007-0488-4

    authors: Ma X,Li X,Wang L

    更新日期:2008-01-01 00:00:00

  • Comparison of Yatabe-Guilford personality test results in retinitis pigmentosa and glaucoma patients.

    abstract:PURPOSE:To determine the psychological state and personality traits of patients with retinitis pigmentosa (RP) or glaucoma so that a closer and better relationship can be developed with the patients. METHODS:The Yatabe-Guilford personality test was administered to 75 RP patients and 42 glaucoma patients. The latter gr...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(02)00621-4

    authors: Igarashi Y,Sato E,Ito A,Miyauchi O,Ikejiri M,Hanawa T,Tsuyama Y,Mizota A,Fujimoto N,Adachi-Usami E

    更新日期:2003-01-01 00:00:00

  • Electroretinographic findings in retinitis pigmentosa.

    abstract::Full-field electroretinograms (ERGs) provide a basis for establishing the diagnosis of widespread progressive forms of retinitis pigmentosa in early life even at a time when fundus abnormalities visible with the ophthalmoscope are minimal or absent. Patients characteristically show delays in rod or cone b-wave implici...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:

    authors: Berson EL

    更新日期:1987-01-01 00:00:00

  • Unilateral disc-shaped cataract with coloboma of lens.

    abstract::A case of unilateral disc-shaped cataract with coloboma of the lens is reported. The patient, a 17-year-old girl, had best corrected visual acuity of 0.01 (+ 9 D) in the right eye and 1.2 in the left eye. Exotropia of 10 Hirschberg degrees was found in her right eye. The visual disturbance of that eye was thought to b...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Kihara Y,Shimomura Y,Omoto T,Fukuda M

    更新日期:1988-01-01 00:00:00

  • Expression of distribution of alpha 2,3-sialyltransferase mRNA in rat cornea.

    abstract::The glycocalyx, present on the surface of the corneal epithelium, contains sialoglycoconjugates. The developmental change in the sialylated residues may be evaluated by examining the expression of the sialyltransferase mRNA. We examined the distribution of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase mRNA in rat cor...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Uehara F,Ozawa M,Iwakiri N,Ohba N

    更新日期:1995-01-01 00:00:00

  • Optic disk drusen with central retinal artery occlusion.

    abstract::An 18-year-old Japanese boy with optic disk drusen associated with left central retinal artery occlusion was reported. Transient central blurred vision, possibly caused by central retinal artery spasm, was noticed as an initial symptom of optic disk drusen in the left eye. Prolonged and repeated spasm might have given...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Uehara M,Inomata H,Yamana Y,Taniguchi Y,Tsuji K

    更新日期:1982-01-01 00:00:00

  • Annual incidences of visual impairment during 10-year period in Mie prefecture, Japan.

    abstract:PURPOSE:To determine the annual incidence of visual impairment in a Japanese population during a 10-year period. METHODS:We examined the physical disability certificates issued yearly between 2004 and 2013 in Mie prefecture, Japan. During this period 2468 visually impaired people were registered under the newly define...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s10384-017-0517-x

    authors: Ikesugi K,Ichio T,Tsukitome H,Kondo M

    更新日期:2017-07-01 00:00:00

  • Sweet's syndrome with panuveitis resembling Behçet's disease.

    abstract:PURPOSE:Sweet's syndrome (SS) is a skin disorder clinically characterized by fever, neutrophilia, and painful edematous plaques that occasionally causes posterior uveitis. We present two cases of SS with panuveitis resembling Behçet's disease (BD). SUBJECTS:Two patients with panuveitis associated with SS. OBSERVATION...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-012-0129-4

    authors: Matsumiya W,Kusuhara S,Yamada Y,Azumi A,Negi A

    更新日期:2012-05-01 00:00:00

  • Retinal cell death by light damage.

    abstract:PURPOSE:To determine the relationship between apoptotic photoreceptor cell death and the duration of light exposure. METHODS:Ten-week-old male albino rats (Wistar strain) were dark-adapted for 2 days and then exposed to intense light for 12 hours, and 1, 2, 3, 7, 14, 21, and 28 days. The presence of apoptosis was conf...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(99)00011-8

    authors: Aonuma H,Yamazaki R,Watanabe I

    更新日期:1999-05-01 00:00:00

  • Patterns of glaucoma progression in retinal nerve fiber and macular ganglion cell-inner plexiform layer in spectral-domain optical coherence tomography.

    abstract:PURPOSE:To evaluate the progressive changes of circumpapillary retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer (GCIPL) thicknesses measured by spectral-domain optical coherence tomography (Cirrus SD-OCT) in open-angle glaucoma. METHODS:One hundred-fourteen eyes of open-angle glaucoma p...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-017-0511-3

    authors: Kim HJ,Jeoung JW,Yoo BW,Kim HC,Park KH

    更新日期:2017-07-01 00:00:00

  • Diagnostic utility of combined retinal ganglion cell count estimates in Japanese glaucoma patients.

    abstract:PURPOSE:To assess the combined estimate of retinal ganglion cell (RGC) count developed by Medeiros et al. as a tool for diagnosis of glaucoma in Japanese patients. STUDY DESIGN:Cross-sectional study. METHODS:Thirty-one eyes of 19 healthy controls and 106 eyes of 70 glaucoma patients underwent standard automated perim...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-017-0540-y

    authors: Sakamoto M,Mori S,Ueda K,Akashi A,Inoue Y,Kurimoto T,Kanamori A,Yamada Y,Nakamura M

    更新日期:2018-01-01 00:00:00

  • Factors associated with polyp regression after intravitreal ranibizumab injections for polypoidal choroidal vasculopathy.

    abstract:PURPOSE:To investigate the predictive factors of polyp regression after intravitreal ranibizumab injections for polypoidal choroidal vasculopathy (PCV). METHODS:Sixty-nine eyes (69 patients) with treatment-naïve PCV received an initial series of 3-monthly intravitreal ranibizumab injections, followed by as-needed inje...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-014-0349-x

    authors: Cho HJ,Han SY,Kim HS,Lee TG,Kim JW

    更新日期:2015-01-01 00:00:00

  • A comparative study of latanoprost (Xalatan) and isopropyl unoprostone (Rescula) in normal and glaucomatous monkey eyes.

    abstract::Latanoprost (PhXA41, Xalatan) and isopropyl unoprostone (UF-021, unoprostone, Rescula) two new prostanoid derivatives, have been shown to reduce intraocular pressure (IOP) significantly in patients with glaucoma or ocular hypertension. This study was designed to compare the ocular hypotensive effects of latanoprost an...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(97)00128-7

    authors: Serle JB,Podos SM,Kitazawa Y,Wang RF

    更新日期:1998-03-01 00:00:00

  • Ocular fundus lesions in systemic lupus erythematosus model mice.

    abstract::We investigated the ocular fundus of (NZWXBXSB) F1 mice, which are considered to be a good model for systemic lupus erythematosus (SLE) with antiphospholipid syndrome. The abnormal fundus findings were documented by fundus photography, and the chorioretinal lesions were studied histopathologically. The incidence of oc...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(98)00023-9

    authors: Nakamura A,Yokoyama T,Kodera S,Zhang D,Hirose S,Shirai T,Kanai A

    更新日期:1998-09-01 00:00:00

  • Suppression of experimental autoimmune uveoretinitis by anti-alphabeta TCR monoclonal antibody.

    abstract:PURPOSE:To evaluate the effects of anti-alphabeta T cell receptor monoclonal antibody (R73) on the induction of experimental autoimmune uveoretinitis (EAU) in rats. METHODS:Lewis rats in which EAU was induced were treated with R73. All rats were examined for the clinical course of EAU, pathological findings of the glo...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(02)00538-5

    authors: Inoki T,Yamagami S,Sakai R,Isobe M,Tsuru T,Kawashima H

    更新日期:2002-09-01 00:00:00

  • The usefulness of infraorbital nerve enlargement on MRI imaging in clinical diagnosis of IgG4-related orbital disease.

    abstract:PURPOSE:To investigate the frequency of infraorbital nerve enlargement (IONE) in orbital lymphoproliferative disorders, and to show that IONE can contribute to the clinical diagnosis of IgG4-related orbital diseases (IgG4-ROD). SUBJECTS AND METHODS:71 cases in which orbital lymphoproliferative disorders were diagnosed...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-012-0151-6

    authors: Ohshima K,Sogabe Y,Sato Y

    更新日期:2012-07-01 00:00:00

  • A new method for quantification of metamorphopsia in patients with epiretinal membrane.

    abstract:PURPOSE:A new method for quantification of metamorphopsia was applied to study distorted vision in patients with epiretinal membrane. METHOD:Sixty-three patients with unilateral epiretinal membrane in the macula were examined. A modified Amsler chart (a grid of black lines on a white background measuring 12 x 12 cm wi...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(00)00173-8

    authors: Shinoda K,Ishida S,Kawashima S,Matsuzaki T,Yamada K,Katsura H

    更新日期:2000-07-01 00:00:00

  • Ocular toxocariasis in Korea.

    abstract:PURPOSE:To analyze the characteristics and clinical manifestations of clinically diagnosed and serologically confirmed ocular toxocariasis in patients. METHODS:Thirty-three eyes of 33 patients diagnosed as having ocular toxocariasis at the Hallym University Medical Center between January 1999 and December 2008 were in...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-010-0909-7

    authors: Kwon SI,Lee JP,Park SP,Lee EK,Huh S,Park IW

    更新日期:2011-03-01 00:00:00

  • Laser subepithelial keratomileusis for low to moderate myopia: 6-month follow-up.

    abstract:PURPOSE:To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. METHODS:This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative myopi...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(02)00473-2

    authors: Lee JB,Choe CM,Seong GJ,Gong HY,Kim EK

    更新日期:2002-05-01 00:00:00

  • Distribution and expression of transforming growth factor-beta and platelet-derived growth factor in the normal and glaucomatous monkey optic nerve heads.

    abstract:PURPOSE:Remodeling of the extracellular matrix occurs in the lamina cribrosa in progressed glaucomatous optic nerve damage including disc cupping. We examined immunohistochemical changes in the transforming growth factor (TGF)-beta and platelet-derived growth factor (PDGF) in the optic nerve head in an experimentally i...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(01)00414-2

    authors: Fukuchi T,Ueda J,Hanyu T,Abe H,Sawaguchi S

    更新日期:2001-11-01 00:00:00

  • Morphological study of the pathogenesis of retinal cotton wool spot.

    abstract::To investigate the true structural changes in retinal cotton wool spots, serial sections of several blocks of retinal corresponding to cotton wool spots obtained from two hypertensive cases were studied by light and electron microscopy. Occlusion of the feeder arteriole and capillaries, and numerous vacuoles of variou...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Murata M,Yoshimoto H

    更新日期:1983-01-01 00:00:00

  • Proteomic analysis of human lens epithelial cells exposed to microwaves.

    abstract:PURPOSE:To study proteomic changes in human lens epithelial cells (HLECs) exposed to 1800-MHz Global System for Mobile Communication (GSM)-like microwaves. METHODS:In three separate experiments, HLECs were exposed and sham-exposed (six dishes each) to 1800-MHz GSM-like radiation for 2 h. The specific absorption rates ...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-007-0483-9

    authors: Li HW,Yao K,Jin HY,Sun LX,Lu DQ,Yu YB

    更新日期:2007-11-01 00:00:00

  • Possible pathogenesis of congenital stationary night blindness.

    abstract::We reported a case of congenital stationary night blindness (CSNB) who showed Schubert-Bornschein type electroretinogram (ERG) in the right eye and nearly normal ERG in the left eye with absolute glaucoma. From the electrophysiological findings of both eyes and histological findings of the enucleated eye, we concluded...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Kato M,Aonuma H,Kawamura H,Miura Y,Watanabe I

    更新日期:1987-01-01 00:00:00

  • Ciclosporin microemulsion preconcentrate treatment of patients with Behçet's disease.

    abstract:PURPOSE:The new microemulsion preconcentrate (MEPC) formulation of ciclosporin has been developed to reduce problems in intestinal absorption and to stabilize fluctuations in blood levels. A multicenter, open-label clinical trial of MEPC was conducted to assess its efficacy and safety in Behçet's disease patients with ...

    journal_title:Japanese journal of ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/s0021-5155(99)00025-8

    authors: Fujino Y,Joko S,Masuda K,Yagi I,Kogure M,Sakai J,Usui M,Kotake S,Matsuda H,Ikeda E,Mochizuki M,Nakamura S,Ohno S

    更新日期:1999-07-01 00:00:00

  • Evaluation of lamina cribrosa thickness and depth in ocular hypertension.

    abstract:PURPOSE:To investigate the differences in thickness and depth of the lamina cribrosa (LC) between ocular hypertension (OH) patients and normal control subjects, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). METHODS:EDI-OCT data were obtained from the subjects in a cross-sect...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-015-0407-z

    authors: Han JC,Choi DY,Kwun YK,Suh W,Kee C

    更新日期:2016-01-01 00:00:00

  • Development of an instrument for measurement of light scattering at the corneal epithelial basement membrane in diabetic patients.

    abstract:PURPOSE:Diabetic complications are associated with abnormality of the basement membranes. We have developed a light-scattering detection system (LSDS) specifically for measurement of light scattering at the corneal epithelial basement membrane, and have determined the reproducibility and clinical significance of the re...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-007-0427-4

    authors: Takahashi N,Wakuta M,Morishige N,Chikama T,Nishida T,Sumii Y

    更新日期:2007-05-01 00:00:00

  • Multicenter genetic study of retinitis pigmentosa in Japan: I. Genetic heterogeneity in typical retinitis pigmentosa.

    abstract::A nationwide, multicenter study of typical retinitis pigmentosa (RP) was carried out in collaboration with 18 hospitals throughout Japan to obtain current information for genetic counseling. We analyzed the genetic heterogeneity of RP based on the parental consanguinity of 434 probands registered during a 6-month peri...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0021-5155(96)00018-4

    authors: Hayakawa M,Fujiki K,Kanai A,Matsumura M,Honda Y,Sakaue H,Tamai M,Sakuma T,Tokoro T,Yura T,Kubota N,Kawano S,Matsui M,Yuzawa M,Oguchi Y,Akeo K,Adachi E,Kimura T,Miyake Y,Horiguchi M,Wakabayashi K,Ishizaka N,Koi

    更新日期:1997-01-01 00:00:00

  • Core vitrectomy preceding triple corneal procedure in patients at high risk for increased posterior chamber pressure.

    abstract::We evaluated the effectiveness of performing a core vitrectomy to prevent intraoperative posterior chamber pressure evaluation in eyes at high risk for development of this complication, prior to penetrating keratoplasty, extracapsular cataract extraction and posterior chamber lens (IOL) implantation. Results in 10 cas...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0021-5155(97)00046-4

    authors: Shimomura Y,Hosotani H,Kiritoshi A,Watanabe H,Tano Y

    更新日期:1997-07-01 00:00:00

  • Expression profiles of cytokines and chemokines in vitreous fluid in diabetic retinopathy and central retinal vein occlusion.

    abstract:PURPOSE:The involvement of cytokines and chemokines in vitreous fluid is important in the development and progression of diabetic retinopathy (DR) and central retinal vein occlusion (CRVO). In this study, the concentrations of cytokines and chemokines in the vitreous fluid of eyes with DR and CRVO were measured and com...

    journal_title:Japanese journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1007/s10384-011-0004-8

    authors: Suzuki Y,Nakazawa M,Suzuki K,Yamazaki H,Miyagawa Y

    更新日期:2011-05-01 00:00:00