Abstract:
:Obstructive sleep apnoea (OSA) is increasingly considered as a risk factor for metabolic disturbances, such as diabetes mellitus or dyslipidaemia. Continuous positive airway pressure (CPAP) therapy, the standard treatment for patients with OSA, may improve various metabolic variables, such as insulin sensitivity, glucose metabolism, lipids, fat distribution and adipokines. Several observational and uncontrolled clinical studies claim an improvement of these metabolic variables through the use of CPAP. However, there is only a limited number of clinical randomised controlled trials (RCTs) evaluating the effect of CPAP on metabolic variables. In this review, we summarise and discuss non-randomised studies and RCTs evaluating the effect of CPAP on metabolic variables in patients with OSA. In summary, the currently available body of evidence does not support a clinically important effect of CPAP treatment on any of the investigated metabolic variables. However, some investigators found small, but statistically significant changes in some metabolic variables, thus beneficial effects of CPAP treatment in selected patient cohorts cannot be excluded. To answer this question, more data from RCTs with well-defined study populations are warranted.
journal_name
Chron Respir Disjournal_title
Chronic respiratory diseaseauthors
Schlatzer C,Schwarz EI,Kohler Mdoi
10.1177/1479972313516882subject
Has Abstractpub_date
2014-02-01 00:00:00pages
41-52issue
1eissn
1479-9723issn
1479-9731pii
11/1/41journal_volume
11pub_type
杂志文章,评审abstract::Nutritional status has been associated with clinical outcome in chronic airflow limitation (CAL), but epidemiological studies are scarce. We aimed to assess the relationship between body mass index (BMI) and CAL, taking into account confounding factors. 18,606 participants (49% male, 21% smokers, mean age: 55.8 ± 11.2...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972315626012
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Effective asthma management requires a multidisciplinary approach that includes; the physician, the patient, and the patient's family. OBJECTIVES:The current study aimed to assess the roles played by community pharmacists toward asthma control together with the barriers hindering their practice and possible...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479973120952679
更新日期:2020-01-01 00:00:00
abstract::Sleep-disordered breathing (SDB) is a chronic condition characterized by repeated breathing pauses during sleep. The reported prevalence of SDB in the general population has increased over time. Furthermore, in the literature, a distinction is made between SDB, obstructive sleep apnea (OSA), and "OSA syndrome" (OSAS)....
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479973120928103
更新日期:2020-01-01 00:00:00
abstract::Sexual expression is an important part of our individual identity and yet, this area is rarely addressed by health professionals. This article will explore the possible reasons for this and will also demonstrate the importance of assessing sexuality in patients with chronic obstructive pulmonary disease (COPD). ...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972306076105
更新日期:2007-01-01 00:00:00
abstract::Recent studies have suggested that an increased peripheral monocyte count predicts a poor outcome in fibrosing interstitial lung disease (ILD). However, the association between an increased monocyte count and acute exacerbations (AEs) of fibrosing ILD remains to be elucidated. Our retrospective cohort study aimed to a...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479973120909840
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abstract::Some patients suffer from clinical symptoms of chronic obstructive pulmonary disease (COPD) but their pulmonary function tests are in the normal range (at risk group). The objective of this study was to discover a practical test to distinguish these patients from non-COPD subjects. A total of 77 subjects including 40 ...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972313507461
更新日期:2013-01-01 00:00:00
abstract::In a world where digital technology has revolutionized the way we work, shop and manage our finances it is unsurprising that digital systems are suggested as potential solutions to delivering clinically and cost-effective care for an aging population with one or more long-term conditions. However, recent evidence sugg...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
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abstract::One of the primary objectives in management of chronic obstructive pulmonary disease (COPD) is preventing decrease in lung function and reducing the annual number of acute exacerbations of COPD (AECOPD). An oral course of systemic corticosteroids is a commonly used treatment in AECOPD. We hypothesize that this treatme...
journal_title:Chronic respiratory disease
pub_type: 信件,随机对照试验
doi:10.1177/1479972317721929
更新日期:2018-05-01 00:00:00
abstract::The aim of this study was to give an in-depth consideration of the chronic obstructive pulmonary disease (COPD) patients' subjective view of the impact of pulmonary rehabilitation (PR) on their lives. A systematic review in PubMed, Embase, CINAHL and PsychInfo databases yielded 3306 articles, of which 387 were duplica...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479972313493796
更新日期:2013-08-01 00:00:00
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journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972306070074
更新日期:2006-01-01 00:00:00
abstract::Acute effects of music and relaxation have not been evaluated in hospitalized subjects with chronic obstructive pulmonary disease (COPD). This study aims to evaluate the acute effects of music and progressive muscle relaxation (PMR) in hospitalized COPD subjects after a recent episode of exacerbation. A Randomized con...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/1479972309346754
更新日期:2009-01-01 00:00:00
abstract::Pulmonary rehabilitation (PR) can improve aerobic exercise capacity, health-related quality of life and dyspnoea in patients with chronic obstructive pulmonary disease (COPD). Recent studies have suggested that exercise training may improve blood pressure and arterial stiffness, albeit in small highly selected cohorts...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972315587515
更新日期:2015-08-01 00:00:00
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journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479972311423111
更新日期:2011-01-01 00:00:00
abstract::Self-management (SM) is defined as the provision of interventions to increase patients' skills and confidence, empowering the individual to take an active part in their disease management. There is uncertainty regarding the optimal format and the short- and long-term benefits of chronic obstructive pulmonary disease (...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479972316687208
更新日期:2017-08-01 00:00:00
abstract::To help answer the question of length of intravenous antibiotics during an acute exacerbation of cystic fibrosis (CF), we had subjects to follow daily home spirometry while on intravenous antibiotics. CF patients, 18 and older, with an acute exacerbation requiring intravenous antibiotics had a daily FEV1. The average ...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972317743756
更新日期:2018-08-01 00:00:00
abstract::There should be a clear pathway through pulmonary rehabilitation and follow-on services. The aim of this survey was to determine the characteristics of the different components of the patient pathway, that is, pulmonary rehabilitation programs, ongoing exercise facilities, and support networks in Northern Ireland. Que...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972308091825
更新日期:2008-01-01 00:00:00
abstract::Patients with chronic obstructive pulmonary disease (COPD) complain of dyspnea and fatigue. We sought to estimate the prevalence of high fatigue in this population and to determine whether individuals with high fatigue had a different response to pulmonary rehabilitation. This observational study was embedded within a...
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pub_type: 杂志文章
doi:10.1177/1479972310396737
更新日期:2011-01-01 00:00:00
abstract::Home noninvasive ventilation (NIV) is widely used to correct nocturnal alveolar hypoventilation in patients with chronic respiratory failure of various etiologies. The most commonly used ventilation mode is pressure support with a backup respiratory rate. This mode requires six main settings, as well as some additiona...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479973119844090
更新日期:2019-01-01 00:00:00
abstract::To inform recommendations for the exercise component of a healthy lifestyle intervention for adults with obesity and treated obstructive sleep apnoea (OSA), we investigated the total energy expenditure (EE) and cardiorespiratory response to weight-supported (cycling) and unsupported (walking) exercise. Individuals wit...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972316643699
更新日期:2017-11-01 00:00:00
abstract::The objective of this study was to investigate the discriminant validity of commonly used depression and anxiety screening tools in order to determine the most suitable tool for patients with chronic obstructive pulmonary disease (COPD). COPD patients (n = 56) completed the Hospital Anxiety and Depression Scale (HADS)...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,多中心研究
doi:10.1177/1479972316634604
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journal_title:Chronic respiratory disease
pub_type: 杂志文章,随机对照试验
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更新日期:2015-11-01 00:00:00
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journal_title:Chronic respiratory disease
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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更新日期:2018-11-01 00:00:00
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journal_title:Chronic respiratory disease
pub_type: 临床试验,杂志文章
doi:10.1177/1479972311422547
更新日期:2011-01-01 00:00:00
abstract::Chronic obstructive pulmonary disease (COPD) imposes a costly burden on healthcare. Pulmonary rehabilitation (PR) is the best practice to better manage COPD to improve patient outcomes and reduce acute hospital care utilization. To evaluate the impact of a once-weekly, eight-week multidisciplinary PR program as an int...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972309104419
更新日期:2009-01-01 00:00:00
abstract::Recent advances in information communication technology allow contact with patients at home through e-Health services (telemedicine, in particular). We provide insights on the state of the art of e-Health and telemedicine for possible wider future clinical use. Telemedicine opportunities are summarized as i) home tele...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
doi:10.1177/1479972309102805
更新日期:2009-01-01 00:00:00
abstract::Health-related quality of life (HRQoL) measurement in cystic fibrosis (CF) allows the inclusion of the patient's perspective in research and clinical practice. HRQoL scales have been used for many purposes and this review focuses on how HRQoL measurement has been implemented in CF research and care. Specifically, the ...
journal_title:Chronic respiratory disease
pub_type: 杂志文章,评审
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更新日期:2009-01-01 00:00:00
abstract::Patients with bronchiectasis (BE) present exacerbations that increase with severity of the disease. We aimed to determine the annual cost of BE treatment according to its severity, determined by FACED score, as well as the parameters associated with higher costs. Multicentre historical cohorts study with patients from...
journal_title:Chronic respiratory disease
pub_type: 杂志文章
doi:10.1177/1479972316643698
更新日期:2016-11-01 00:00:00
abstract::Dyspnea-related anxiety may lead to reduced quality of life and functional disability through fearful avoidance of dyspnea-evoking activity. We describe the validation of a generic - diagnosis-independent - instrument assessing dyspnea-related anxiety. A total of 187 patients with respiratory diseases completed the Br...
journal_title:Chronic respiratory disease
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journal_title:Chronic respiratory disease
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更新日期:2018-05-01 00:00:00