Abstract:
:Understanding brain circuits begins with an appreciation of their component parts - the cells. Although GABAergic interneurons are a minority population within the brain, they are crucial for the control of inhibition. Determining the diversity of these interneurons has been a central goal of neurobiologists, but this amazing cell type has so far defied a generalized classification system. Interneuron complexity within the telencephalon could be simplified by viewing them as elaborations of a much more finite group of developmentally specified cardinal classes that become further specialized as they mature. Our perspective emphasizes that the ultimate goal is to dispense with classification criteria and directly define interneuron types by function.
journal_name
Naturejournal_title
Natureauthors
Kepecs A,Fishell Gdoi
10.1038/nature12983subject
Has Abstractpub_date
2014-01-16 00:00:00pages
318-26issue
7483eissn
0028-0836issn
1476-4687pii
nature12983journal_volume
505pub_type
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