Abstract:
:Multiscale simulations are essential in the biomedical domain to accurately model human physiology. We present a modular approach for designing, constructing and executing multiscale simulations on a wide range of resources, from laptops to petascale supercomputers, including combinations of these. Our work features two multiscale applications, in-stent restenosis and cerebrovascular bloodflow, which combine multiple existing single-scale applications to create a multiscale simulation. These applications can be efficiently coupled, deployed and executed on computers up to the largest (peta) scale, incurring a coupling overhead of 1-10% of the total execution time.
journal_name
Interface Focusjournal_title
Interface focusauthors
Groen D,Borgdorff J,Bona-Casas C,Hetherington J,Nash RW,Zasada SJ,Saverchenko I,Mamonski M,Kurowski K,Bernabeu MO,Hoekstra AG,Coveney PVdoi
10.1098/rsfs.2012.0087subject
Has Abstractpub_date
2013-04-06 00:00:00pages
20120087issue
2eissn
2042-8898issn
2042-8901pii
rsfs20120087journal_volume
3pub_type
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