当前位置： SCI文献检索 > ATHEROSCLEROSIS期刊下所有文献 > Postprandial effects of a high salt meal on serum sodium, arterial stiffness, markers of nitric oxide production and markers of endothelial function.

Postprandial effects of a high salt meal on serum sodium, arterial stiffness, markers of nitric oxide production and markers of endothelial function.

Abstract：

AIM:The aim of the study was to determine if a high salt meal containing 65 mmol Na causes a rise in sodium concentrations and a reduction in plasma nitrate/nitrite concentrations (an index of nitric oxide production). Secondary aims were to determine the effects of a high salt meal on augmentation index (AIx) a measure of arterial stiffness and markers of endothelial function. METHODS AND RESULTS:In a randomised cross-over study 16 healthy normotensive adults consumed a low sodium soup containing 5 mmol Na and a high sodium soup containing 65 mmol Na. Sodium, plasma nitrate/nitrite, endothelin-1 (ET-1), C-reactive protein (CRP), vasopressin (AVP) and atrial natriuretic peptide (ANP) concentrations before and every 30 min after the soup for 2 h. Blood pressure (BP) and AI were also measured at these time points. There were significant increases in serum sodium, osmolality and chloride in response to the high sodium meal. However plasma nitrate/nitrite concentrations were not different between meals (meal p = 0.812; time p = 0.45; meal × time interaction p = 0.50). Plasma ANP, AVP and ET-1 were not different between meals. AI was significantly increased following the high sodium meal (p = 0.02) but there was no effect on BP. CONCLUSIONS:A meal containing 65 mmol Na increases serum sodium and arterial stiffness but does not alter postprandial nitrate/nitrite concentration in healthy normotensive individuals. Further research is needed to explore the mechanism by which salt affects vascular function in the postprandial period. This trial was registered with the Australian and New Zealand Clinical Trials Registry Unique Identifier: ACTRN12611000583943http://www.anzctr.org.au/trial_view.aspx?ID=343019.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Dickinson KM,Clifton PM,Burrell LM,Barrett PH,Keogh JB

doi

10.1016/j.atherosclerosis.2013.10.032

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

211-6

issue

1

eissn

0021-9150

issn

1879-1484

pii

S0021-9150(13)00632-1

journal_volume

232

pub_type

杂志文章,随机对照试验

相关文献

ATHEROSCLEROSIS文献大全
  • Adipose tissue diacylglycerol acyltransferase activity and blood lipoprotein triglyceride enrichment in women with abdominal obesity.

    abstract：UNLABELLED:Previous studies have suggested altered triglyceride (TG) storage in patients with abdominal obesity and blood lipid disorders. OBJECTIVE:We hypothesized that women with abdominal obesity and a dysmetabolic profile have low DGAT activity in their abdominal fat compartments. METHODS:Paired omental (OM) and ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2013.12.041

    authors： Côté JA,Nadeau M,Leboeuf M,Blackburn L,Tchernof A

    更新日期：2014-03-01 00:00:00

  • Effects of bezafibrate on the expression of endothelial nitric oxide synthase gene and its mechanisms in cultured bovine endothelial cells.

    abstract：OBJECTIVE:Peroxisome proliferator-activated receptors alpha (PPARalpha) is a target gene for atherosclerosis and cardiovascular diseases. However, effects of PPARalpha on endothelial nitric oxide synthase (eNOS) remain unknown. We investigated the eNOS regulation by bezafibrate, a ligand of PPARalpha, and involved sign...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2005.09.008

    authors： Wang Y,Wang Y,Yang Q,Yan JT,Zhao C,Cianflone K,Wang DW

    更新日期：2006-08-01 00:00:00

  • Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation.

    abstract：:Leukotriene B(4) (LTB(4)) is a pro-inflammatory lipid mediator generated by the enzymes 5-lipoxygenase (5-LO) and LTA(4)-hydrolase. LTB(4) signals primarily through its G protein-coupled receptor BLT1, which is highly expressed on specific leukocyte subsets. Recent genetic studies in humans as well as knockout studies...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2009.11.031

    authors： Kristo F,Hardy GJ,Anderson TJ,Sinha S,Ahluwalia N,Lin AY,Passeri J,Scherrer-Crosbie M,Gerszten RE

    更新日期：2010-05-01 00:00:00

  • Association between nutrient intake and peripheral artery disease: results from the InCHIANTI study.

    abstract：BACKGROUND:Little is known about the relationship between dietary patterns and peripheral arterial disease (PAD). Our aim was to estimate the association between nutrient intake and diagnosis of PAD. METHODS AND RESULTS:We assessed the nutrient intake of 1251 home-dwelling subjects enrolled in the InCHIANTI study, mea...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.atherosclerosis.2005.07.016

    authors： Antonelli-Incalzi R,Pedone C,McDermott MM,Bandinelli S,Miniati B,Lova RM,Lauretani F,Ferrucci L

    更新日期：2006-05-01 00:00:00

  • Impact of attenuated-signal plaque observed by intravascular ultrasound on vessel response after drug-eluting stent implantation.

    abstract：BACKGROUND AND AIMS:The aim of this study was to investigate the impact of attenuated-signal plaque (ASP) observed by intravascular ultrasound (IVUS) on vessel response after drug-eluting stent implantation. METHODS:Data were derived from the IVUS cohort of the J-DESsERT trial comparing paclitaxel- and sirolimus-eluti...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.atherosclerosis.2017.02.009

    authors： Kitahara H,Waseda K,Sakamoto K,Yamada R,Huang CC,Nakatani D,Sakata K,Kawarada O,Yock PG,Matsuyama Y,Yokoi H,Nakamura M,Muramatsu T,Nanto S,Fitzgerald PJ,Honda Y

    更新日期：2017-04-01 00:00:00

  • Lipid metabolism after an oral fat test meal is affected by age-associated features of metabolic syndrome, but not by age.

    abstract：OBJECTIVE:Postprandial lipemia influences the development of atherosclerosis. Age has been defined as a regulating factor of the extent of postprandial lipemia, but its independence of other age-associated phenotypic features, such as metabolic syndrome, has not been fully elucidated. METHODS:To investigate if age is ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2012.10.052

    authors： Perez-Caballero AI,Alcala-Diaz JF,Perez-Martinez P,Garcia-Rios A,Delgado-Casado N,Marin C,Yubero-Serrano E,Camargo A,Caballero J,Malagon MM,Tinahones FJ,Perez-Jimenez F,Lopez-Miranda J,Delgado-Lista J

    更新日期：2013-01-01 00:00:00

  • Genetic and pharmacological inhibition of the 5-lipoxygenase/leukotriene pathway in atherosclerotic lesion development in ApoE deficient mice.

    abstract：:The 5-lipoxygenase (5-LO) catalyzed formation of leukotriene (LT) lipid mediators is a pathway contributing to inflammatory events in asthma and more recently has been associated with cardiovascular disease. However, the relative impact of this pathway in atherogenesis has been controversial and a variety of mixed res...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2008.07.045

    authors： Cao RY,St Amand T,Gräbner R,Habenicht AJ,Funk CD

    更新日期：2009-04-01 00:00:00

  • Detection of atherosclerotic cardiovascular disease influences the perceived need for aggressive lipid management.

    abstract：BACKGROUND AND AIMS:Overt atherosclerotic cardiovascular disease (ASCVD) warrants aggressive lipid lowering. Imaging for ambiguous symptoms suggesting ischemia or for clarification of CV risk in asymptomatic individuals often uncovers previously unknown ASCVD. Guidelines do not provide clear recommendations for aggress...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2017.06.006

    authors： Mancini GBJ,Gupta M,Tsigoulis M,Cannon CP,Genest J,Ray KK,Santos RD,Watts GF,Raggi P

    更新日期：2017-08-01 00:00:00

  • Increased platelet Fc receptor expression in diabetes is limited to those with type 2 disease and low LDL cholesterol levels.

    abstract：:A potential role for the platelet Fc gammaRIIA immunoreceptor (FcR) in collagen-mediated platelet activation associated with diabetes has recently been described. This study was undertaken to prospectively determine which diabetes patient population (type 1, type 2, or both) was more likely to over express platelet Fc...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2005.06.002

    authors： Calverley DC,Baldermann LV,Heldt ML,Kinney GL,Hokanson JE

    更新日期：2006-03-01 00:00:00

  • Increased atherosclerosis in mice with increased vascular biglycan content.

    abstract：OBJECTIVE:The response to retention hypothesis of atherogenesis proposes that atherosclerosis is initiated via the retention of atherogenic lipoproteins by vascular proteoglycans. Co-localization studies suggest that of all the vascular proteoglycans, biglycan is the one most closely co-localized with LDL. The goal of ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2014.03.037

    authors： Thompson JC,Tang T,Wilson PG,Yoder MH,Tannock LR

    更新日期：2014-07-01 00:00:00

  • Analysis of the postulated interaction between the angiotensin II sub-type 1 receptor gene A1166C polymorphism and the insertion/deletion polymorphism of the angiotensin converting enzyme gene on risk of myocardial infarction.

    abstract：:A synergistic interaction between the insertion/deletion (I/D) polymorphism within the angiotensin-converting enzyme (ACE) gene and an A/C transversion at nucleotide position 1166 within the angiotensin II sub-type 1 receptor (AT1R) gene on risk of myocardial infarction has been reported. The risk associated with the ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(00)00438-x

    authors： Steeds RP,Wardle A,Smith PD,Martin D,Channer KS,Samani NJ

    更新日期：2001-01-01 00:00:00

  • P-selectin and subclinical and clinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis (MESA).

    abstract：OBJECTIVE:P-selectin is a cellular adhesion molecule that has been shown to be crucial in development of coronary heart disease (CHD). We sought to determine the role of P-selectin on the risk of atherosclerosis in a large multi-ethnic population. METHODS:Data from the Multi-Ethnic Study of Atherosclerosis (MESA), inc...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.atherosclerosis.2015.02.036

    authors： Bielinski SJ,Berardi C,Decker PA,Kirsch PS,Larson NB,Pankow JS,Sale M,de Andrade M,Sicotte H,Tang W,Hanson NQ,Wassel CL,Polak JF,Tsai MY

    更新日期：2015-05-01 00:00:00

  • Coadministration of colesevelam hydrochloride with atorvastatin lowers LDL cholesterol additively.

    abstract：:Colesevelam hydrochloride is a novel, potent, non-absorbed lipid-lowering agent previously shown to reduce low density lipoprotein (LDL) cholesterol. To examine the efficacy and safety of coadministration of colesevelam and atorvastatin, administration of these agents alone or in combination was examined in a double-b...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0021-9150(01)00437-3

    authors： Hunninghake D,Insull W Jr,Toth P,Davidson D,Donovan JM,Burke SK

    更新日期：2001-10-01 00:00:00

  • Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease.

    abstract：OBJECTIVE:Several studies have shown that periodontitis is a risk factor for cardiovascular diseases. There is an association between inflammation and endothelial dysfunction. The purpose of this study was to evaluate endothelial function in patients with coronary artery disease (CAD) who had periodontitis. METHODS AN...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2009.03.037

    authors： Higashi Y,Goto C,Hidaka T,Soga J,Nakamura S,Fujii Y,Hata T,Idei N,Fujimura N,Chayama K,Kihara Y,Taguchi A

    更新日期：2009-10-01 00:00:00

  • Antiatherogenic effect of angiotensin converting enzyme inhibitor (benazepril) and angiotensin II receptor antagonist (valsartan) in the cholesterol-fed rabbits.

    abstract：:The purpose of this study was to determine whether an angiotensin converting enzyme (ACE) inhibitor, benazepril, and an angiotensin receptor antagonist, valsartan, would decrease atherosclerotic severity in cholesterol-fed rabbits. Male rabbits were fed either: (a) normal rabbit chow; (b) 2% cholesterol diet; (c) 2% c...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(98)00309-8

    authors： Li J,Hirose N,Kawamura M,Arai Y

    更新日期：1999-04-01 00:00:00

  • Variants in the cholesterol ester transfer protein and lipoprotein lipase genes are predictors of plasma cholesterol response to dietary change.

    abstract：:There are no definitive explanations as to why individuals with hypercholesterolemia, a major cardiovascular risk factor, respond differently to dietary change. Fifty five free-living individuals completed a double crossover trial with two dietary regimens, a high saturated fat diet (providing 21% energy from saturate...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0021-9150(99)00490-6

    authors： Wallace AJ,Mann JI,Sutherland WH,Williams S,Chisholm A,Skeaff CM,Gudnason V,Talmud PJ,Humphries SE

    更新日期：2000-10-01 00:00:00

  • Serum complement and familial combined hyperlipidemia.

    abstract：:Familial combined hyperlipidemia (FCHL) is one of the most common inherited lipid disorders. Resistance of adipocytes to the effects of acylation stimulating protein (ASP) may contribute to ineffective triglyceride synthesis and thereby prolonged postprandial lipemia and increased fatty acid flux to the liver seen in ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(96)06054-6

    authors： Ylitalo K,Porkka KV,Meri S,Nuotio I,Suurinkeroinen L,Vakkilainen J,Pajukanta P,Viikari JS,Peltonen L,Ehnholm C,Taskinen MR

    更新日期：1997-03-21 00:00:00

  • Markers of endothelial dysfunction and low-grade inflammation are associated in the offspring of type 2 diabetic subjects.

    abstract：:The offspring of type 2 diabetic patients are at elevated risk for type 2 diabetes and cardiovascular disease. The aim of our study was to characterize the role of various biomarkers of endothelial activation in a cohort of offspring of type 2 diabetic subjects and to assess the association of adhesion molecules with ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2007.04.021

    authors： Ruotsalainen E,Vauhkonen I,Salmenniemi U,Pihlajamäki J,Punnonen K,Kainulainen S,Jalkanen S,Salmi M,Laakso M

    更新日期：2008-03-01 00:00:00

  • Low dose apolipoprotein A-I rescues carotid arteries from inflammation in vivo.

    abstract：:This study investigates the ability of a single, low dose of apolipoprotein (apo) A-I, the main lipoprotein of high density lipoproteins (HDL), to inhibit acute vascular inflammation in normocholesterolemic New Zealand White rabbits. Acute vascular inflammation was induced in the animals by placing a non-occlusive, si...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2007.05.008

    authors： Puranik R,Bao S,Nobecourt E,Nicholls SJ,Dusting GJ,Barter PJ,Celermajer DS,Rye KA

    更新日期：2008-01-01 00:00:00

  • Efficacy of clinical diagnostic criteria for familial hypercholesterolemia genetic testing in Poland.

    abstract：BACKGROUND AND AIMS:Familial hypercholesterolemia (FH), which leads to premature cardiovascular events, still remains underrecognized and undertreated in most countries. Untreated FH individuals aged 20-39 years are at 100-fold higher risk of mortality from coronary heart disease compared to those of a general populati...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2016.03.025

    authors： Mickiewicz A,Chmara M,Futema M,Fijalkowski M,Chlebus K,Galaska R,Bandurski T,Pajkowski M,Zuk M,Wasag B,Limon J,Rynkiewicz A,Gruchala M

    更新日期：2016-06-01 00:00:00

  • Relationship of serum ferritin concentrations with metabolic cardiovascular risk factors in men without evidence for coronary artery disease.

    abstract：:Elevated serum ferritin concentrations between 200 and 500 microg/l have been found to be a strong risk factor for acute myocardial infarction in Finnish men, but the reason for this association is still uncertain. In the Finnish population ferritin concentrations correlated with factors of insulin resistance syndrome...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(96)05994-1

    authors： Halle M,König D,Berg A,Keul J,Baumstark MW

    更新日期：1997-02-10 00:00:00

  • Fibroblast growth factor 23, left ventricular mass, and left ventricular hypertrophy in community-dwelling older adults.

    abstract：OBJECTIVES:In chronic kidney disease (CKD), high FGF23 concentrations are associated with left ventricular hypertrophy (LVH), cardiovascular events, and death. The associations of FGF23 with left ventricular mass (LVM) and LVH in the general population and the influence of CKD remains uncertain. METHODS:C-terminal pla...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2013.09.002

    authors： Jovanovich A,Ix JH,Gottdiener J,McFann K,Katz R,Kestenbaum B,de Boer IH,Sarnak M,Shlipak MG,Mukamal KJ,Siscovick D,Chonchol M

    更新日期：2013-11-01 00:00:00

  • The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis.

    abstract：BACKGROUND:Atherosclerosis is characterized by lipid accumulation and chronic inflammation in the arterial wall. Elevated levels of apolipoprotein (apo) B-containing lipoproteins are a risk factor for cardiovascular disease (CVD). By contrast, plasma levels of functional high-density lipoprotein (HDL) and apoA-I are pr...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2016.03.003

    authors： Hennuyer N,Duplan I,Paquet C,Vanhoutte J,Woitrain E,Touche V,Colin S,Vallez E,Lestavel S,Lefebvre P,Staels B

    更新日期：2016-06-01 00:00:00

  • Endothelial dysfunction and arterial stiffness in patients with systemic lupus erythematosus: A systematic review and meta-analysis.

    abstract：BACKGROUND AND AIMS:Non-invasive surrogates of cardiovascular (CV) disease such as endothelial dysfunction (ED) and peripheral arterial stiffness (AS) have been evaluated in systemic lupus erythematosus (SLE) patients. The aim of this study was to systematically review and meta-analyze reports of cardiovascular disease...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2020.01.028

    authors： Mendoza-Pinto C,Rojas-Villarraga A,Molano-González N,García-Carrasco M,Munguía-Realpozo P,Etchegaray-Morales I,Morales-Sánchez H,Berra-Romani R,Cervera R

    更新日期：2020-03-01 00:00:00

  • Characterization of atherosclerosis in a patient with familial high-density lipoprotein deficiency.

    abstract：:We describe the cardiovascular state of a 60-year-old homozygous patient with familial HDL deficiency (Tangier disease). The patient was examined by coronary angiography and intravascular ultrasound because of chest pain at rest and on exertion. We found a normal left ventricular function, moderately diffuse coronary ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(94)90205-4

    authors： Walter M,Kerber S,Fechtrup C,Seedorf U,Breithardt G,Assmann G

    更新日期：1994-10-01 00:00:00

  • Coordinate changes in the low density lipoprotein receptor activity of liver and mononuclear cells in the rabbit.

    abstract：:In the rabbit, dietary cholesterol downregulates the hepatic LDL receptor and concomitant treatment with 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors partly restores its expression. The aim of this study was to determine whether the LDL receptor activity of circulating mononuclear cells would r...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(93)90112-8

    authors： Roach PD,Kerry NL,Whiting MJ,Nestel PJ

    更新日期：1993-07-01 00:00:00

  • Impact of implanted bone marrow progenitor cell composition on limb salvage after cell implantation in patients with critical limb ischemia.

    abstract：OBJECTIVE:The aim of this study is to identify which factors influence limb salvage after bone marrow mononuclear cell implantation (BMI) in patients with chronic critical limb ischemia (CLI). METHODS:Thirteen no-option CLI patients treated with BMI were enrolled in the present study. Limb ischemia was assessed using ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2009.08.028

    authors： Iso Y,Soda T,Sato T,Sato R,Kusuyama T,Omori Y,Shoji M,Koba S,Katagiri T,Kobayashi Y,Suzuki H

    更新日期：2010-03-01 00:00:00

  • Effects of dietary sunflowerseed oil and marine oil on platelet membrane fluidity, arterial thrombosis, and platelet responses in rats.

    abstract：:The relationships among platelet membrane fluidity, arterial thrombosis tendency, and platelet aggregation and prostanoid formation were investigated after feeding rats diets enriched in (n-6) or (n-3) polyunsaturated fatty acids. For at least 8 weeks, rats were fed a control diet containing 5 energy % (en%) sunflower...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(86)90101-2

    authors： Rand ML,Hennissen AA,Hornstra G

    更新日期：1986-12-01 00:00:00

  • Effect of hyperapo B LDL on cholesterol esterification in THP-1 macrophages.

    abstract：:Hyperapobetalipoproteinemia (hyperapo B), a common disorder associated with coronary artery disease, is characterized by an increased number of small, dense, low density lipoprotein (LDL) particles. The cellular mechanisms responsible for early atherosclerosis in hyperapo B are unknown. We tested the hypothesis that h...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(93)90081-5

    authors： Kafonek SD,Raikhel I,Bachorik PS,Kwiterovich PO Jr

    更新日期：1993-08-01 00:00:00

  • A year-long study of changes induced by thyroidectomy in the plasma lipid and lipoprotein spectrum in the European badger.

    abstract：:Hypothyroidism is associated with hypercholesterolemia and increased risk for atherosclerotic disease. The European badger exhibits large seasonal changes in thyroid activity and the annual minimum of plasma thyroxine level in this species occurs at the same period of the year (i.e. late fall) as a pronounced hypercho...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(84)90190-4

    authors： Laplaud PM,Beaubatie L,Maurel D,Catanzano G

    更新日期：1984-11-01 00:00:00