Carotid atherosclerosis and right ventricular diastolic dysfunction in a sample of hypertensive Nigerian patients.

Abstract:

AIM:To determine the association of carotid atherosclerosis and right ventricular diastolic dysfunction (DD) among treated hypertensive Nigerian patients. METHODS:This was a single center cross-sectional study performed at the Cardiology Clinic of LAUTECH Teaching Hospital, Ogbomoso, Nigeria between January and December 2012. The study included 122 hypertensive Nigerians (mean age, 57.3±14.7 years, 36.9% women). Patients' clinical, demographic, and echocardiographic parameters were obtained. Diastolic dysfunction was assessed with the trans-tricuspid Doppler flow. RESULTS:Patients with DD were significantly older than those with normal diastolic function. Mean and maximum carotid intima media thickness measurements were significantly higher among patients with right ventricular DD than in those with normal diastolic function. Mean systolic blood pressure (148.3±31.9 vs 128.0±2.8 mm Hg, P=0.049) and interventricular septal thickness in diastole (12.8±2.3 vs 11.6±2.8 mm, P=0.048) were significantly higher and tricuspid annular pulmonary systolic excursion (33.6±4.9 vs 23.0±4.2 mm, P=0.035) was significantly lower in patients with right ventricular DD than in those with normal diastolic function. Carotid intima media thickness measurements were correlated with early trans-tricuspid Doppler flow and early transtricuspid diastolic flow/late right atrial transtricupsid diastolic flow ratio. CONCLUSION:Right ventricular DD in hypertensive patients was significantly correlated with increased carotid atherosclerosis. Carotid intima media thickness measurements may therefore be a surrogate marker for DD in hypertensive subjects.

journal_name

Croat Med J

journal_title

Croatian medical journal

authors

Akintunde AA,Adebayo PB,Aremu AA,Opadijo OG

doi

10.3325/cmj.2013.54.555

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

555-60

issue

6

eissn

0353-9504

issn

1332-8166

journal_volume

54

pub_type

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