Early urban impact on Mediterranean coastal environments.

Abstract:

:A common belief is that, unlike today, ancient urban areas developed in a sustainable way within the environmental limits of local natural resources and the ecosystem's capacity to respond. This long-held paradigm is based on a weak knowledge of the processes underpinning the emergence of urban life and the rise of an urban-adapted environment in and beyond city boundaries. Here, we report a 6000-year record of environmental changes around the port city of Akko (Acre), Israel, to analyse ecological processes and patterns stemming from the emergence and growth of urban life. We show that early urban development deeply transformed pre-existing ecosystems, swiftly leading to an urban environment already governed by its own ecological rules and this, since the emergence of the cities.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Kaniewski D,Van Campo E,Morhange C,Guiot J,Zviely D,Shaked I,Otto T,Artzy M

doi

10.1038/srep03540

subject

Has Abstract

pub_date

2013-12-18 00:00:00

pages

3540

issn

2045-2322

pii

srep03540

journal_volume

3

pub_type

历史文章,杂志文章
  • Dyssynergic patterns of defecation in constipated adolescents and young adults with anorectal malformations.

    abstract::We aimed to evaluate the etiologies of constipation in patients with anorectal malformations having a good prognosis for bowel control but a high risk of constipation. We included twenty-five patients from the Odense university hospital in Denmark. Patients were subjected to colon transit time examination and high res...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-76841-5

    authors: Bjørsum-Meyer T,Christensen P,Baatrup G,Jakobsen MS,Asmussen J,Qvist N

    更新日期:2020-11-12 00:00:00

  • Quasisolitons in self-diffusive excitable systems, or Why asymmetric diffusivity obeys the Second Law.

    abstract::Solitons, defined as nonlinear waves which can reflect from boundaries or transmit through each other, are found in conservative, fully integrable systems. Similar phenomena, dubbed quasi-solitons, have been observed also in dissipative, "excitable" systems, either at finely tuned parameters (near a bifurcation) or in...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep30879

    authors: Biktashev VN,Tsyganov MA

    更新日期:2016-08-05 00:00:00

  • Methadone induces testosterone suppression in patients with opioid addiction.

    abstract::Sex hormones may have a role in the pathophysiology of substance use disorders, as demonstrated by the association between testosterone and addictive behaviour in opioid dependence. Although opioid use has been found to suppress testosterone levels in men and women, the extent of this effect and how it relates to meth...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep06189

    authors: Bawor M,Dennis BB,Samaan MC,Plater C,Worster A,Varenbut M,Daiter J,Marsh DC,Desai D,Steiner M,Anglin R,Coote M,Pare G,Thabane L,Samaan Z

    更新日期:2014-08-26 00:00:00

  • Multidirectional digital scanned light-sheet microscopy enables uniform fluorescence excitation and contrast-enhanced imaging.

    abstract::Light-sheet fluorescence microscopy (LSFM) has emerged as a powerful method for rapid and optically efficient 3D microscopy. Initial LSFM designs utilized a static sheet of light, termed selective plane illumination microscopy (SPIM), which exhibited shadowing artifacts and deteriorated contrast due to light scatterin...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-32367-5

    authors: Glaser AK,Chen Y,Yin C,Wei L,Barner LA,Reder NP,Liu JTC

    更新日期:2018-09-17 00:00:00

  • Genome-wide analysis of enhancer RNA in gene regulation across 12 mouse tissues.

    abstract::Enhancers play a crucial role in gene regulation but the participation of enhancer transcripts (i.e. enhancer RNA, eRNAs) in regulatory systems remains unclear. We provide a computational analysis on eRNAs using genome-wide data across 12 mouse tissues. The expression of genes targeted by transcribing enhancer is posi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep12648

    authors: Cheng JH,Pan DZ,Tsai ZT,Tsai HK

    更新日期:2015-07-29 00:00:00

  • Dipeptidyl Peptidase-4 Inhibitor Increases Vascular Leakage in Retina through VE-cadherin Phosphorylation.

    abstract::The inhibitors of CD26 (dipeptidyl peptidase-4; DPP4) have been widely prescribed to control glucose level in diabetic patients. DPP4-inhibitors, however, accumulate stromal cell-derived factor-1α (SDF-1α), a well-known inducer of vascular leakage and angiogenesis both of which are fundamental pathophysiology of diabe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep29393

    authors: Lee CS,Kim YG,Cho HJ,Park J,Jeong H,Lee SE,Lee SP,Kang HJ,Kim HS

    更新日期:2016-07-06 00:00:00

  • Effects of FSH and the weather during induced ovulation and timed artificial insemination to increase jenny conception rates.

    abstract::Experiments were conducted to improve jenny conception rates through induced ovulation and timed insemination. Jennies in control, hCG and LH groups were injected intramuscularly with saline alone or saline containing hCG or LH, respectively, when the dominant follicle diameter reached 35 mm. Then, follicle developmen...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-39757-3

    authors: Chang ZL,Li BX,Liu B,Yao L,Yu J,Jiang GM,Tan JH

    更新日期:2019-03-01 00:00:00

  • Bacterial community structure and function shift along a successional series of tidal flats in the Yellow River Delta.

    abstract::Coastal ecosystems play significant ecological and economic roles but are threatened and facing decline. Microbes drive various biogeochemical processes in coastal ecosystems. Tidal flats are critical components of coastal ecosystems; however, the structure and function of microbial communities in tidal flats are poor...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep36550

    authors: Lv X,Ma B,Yu J,Chang SX,Xu J,Li Y,Wang G,Han G,Bo G,Chu X

    更新日期:2016-11-08 00:00:00

  • Role of Mast Cells in clearance of Leishmania through extracellular trap formation.

    abstract::Mast Cells (MCs) are one of the first immune cells encountered by invading pathogens. Their presence in large numbers in the superficial dermis, where Leishmania is encountered, suggests that they may play a critical role in immune responses to Leishmania. In this study the interactions of Leishmania donovani, the cau...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-12753-1

    authors: Naqvi N,Ahuja K,Selvapandiyan A,Dey R,Nakhasi H,Puri N

    更新日期:2017-10-16 00:00:00

  • Retinal Vascular Density as A Novel Biomarker of Acute Renal Injury after Acute Coronary Syndrome.

    abstract::Iodinated contrast agent (ICA)-induced acute kidney injury (AKI) following acute coronary syndrome (ACS) is a frequent complication, which may lead to chronic kidney disease and increased mortality. Optical coherence tomography angiography (OCT-A) of the retina is new tool delivering a rapid and noninvasive assessment...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44647-9

    authors: Alan G,Guenancia C,Arnould L,Azemar A,Pitois S,Maza M,Bichat F,Zeller M,Gabrielle PH,Bron AM,Creuzot-Garcher C,Cottin Y

    更新日期:2019-05-30 00:00:00

  • Morphological Characteristics of Posterior Wall Fragments Associated with Acetabular Both-column Fracture.

    abstract::Treatment of both-column fractures with posterior wall involvement is still a controversial topic. This type of posterior wall fracture is different from isolated acetabular posterior wall fracture (AO/OTA62-A1). The aim of this study is to compare the morphology of the posterior wall fragments of these two fracture p...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-56838-5

    authors: Tian S,Chen Y,Yin Y,Zhang R,Hou Z,Zhang Y

    更新日期:2019-12-27 00:00:00

  • Long non-coding RNAs harboring miRNA seed regions are enriched in prostate cancer exosomes.

    abstract::Long non-coding RNAs (lncRNAs) form the largest transcript class in the human transcriptome. These lncRNA are expressed not only in the cells, but they are also present in the cell-derived extracellular vesicles such as exosomes. The function of these lncRNAs in cancer biology is not entirely clear, but they appear to...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24922

    authors: Ahadi A,Brennan S,Kennedy PJ,Hutvagner G,Tran N

    更新日期:2016-04-22 00:00:00

  • NMDA receptors in mouse anterior piriform cortex initialize early odor preference learning and L-type calcium channels engage for long-term memory.

    abstract::The interactions of L-type calcium channels (LTCCs) and NMDA receptors (NMDARs) in memories are poorly understood. Here we investigated the specific roles of anterior piriform cortex (aPC) LTCCs and NMDARs in early odor preference memory in mice. Using calcium imaging in aPC slices, LTCC activation was shown to be dep...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep35256

    authors: Mukherjee B,Yuan Q

    更新日期:2016-10-14 00:00:00

  • Effects of Nanotexture on Electrical Profiling of Single Tumor Cell and Detection of Cancer from Blood in Microfluidic Channels.

    abstract::Microfluidic channels have been implemented to detect cancer cells from blood using electrical measurement of each single cell from the sample. Every cell provided characteristic current profile based on its mechano-physical properties. Cancer cells not only showed higher translocation time and peak amplitude compared...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep13031

    authors: Islam M,Bellah MM,Sajid A,Hasan MR,Kim YT,Iqbal SM

    更新日期:2015-09-16 00:00:00

  • A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging.

    abstract::An ongoing challenge in biomedical research is the search for simple, yet robust assays using 3D cell cultures for toxicity screening. This study addresses that challenge with a novel spheroid assay, wherein spheroids, formed by magnetic 3D bioprinting, contract immediately as cells rearrange and compact the spheroid ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep13987

    authors: Tseng H,Gage JA,Shen T,Haisler WL,Neeley SK,Shiao S,Chen J,Desai PK,Liao A,Hebel C,Raphael RM,Becker JL,Souza GR

    更新日期:2015-09-14 00:00:00

  • Optimization and standardization of the culturomics technique for human microbiome exploration.

    abstract::Culturomics is a high-throughput culture approach that has dramatically contributed to the recent renewal of culture. While metagenomics enabled substantial advances in exploring the microbiota, culturomics significantly expanded our knowledge regarding the bacterial gut repertoire through the discovery and the descri...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-66738-8

    authors: Diakite A,Dubourg G,Dione N,Afouda P,Bellali S,Ngom II,Valles C,Tall ML,Lagier JC,Raoult D

    更新日期:2020-06-15 00:00:00

  • Trivalent Y3+ ionic sensor development based on (E)-Methyl-N'-nitrobenzylidene-benzenesulfonohydrazide (MNBBSH) derivatives modified with nafion matrix.

    abstract::(E)-Methyl-N'-nitrobenzylidene-benzenesulfonohydrazide (MNBBSH) compounds were synthesized using a condensation procedure from the derivatives of nitrobenzaldehyde and 4-Methyl-benzenesulfonylhydrazine, which crystallized in ethanol and methanol as well as characterized by FTIR, UV-Vis, 1H-NMR, and 13C-NMR. MNBBSH str...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05703-4

    authors: Hussain MM,Rahman MM,Arshad MN,Asiri AM

    更新日期:2017-07-19 00:00:00

  • Levels of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in raw wastewater as an innovative perspective for investigating population-wide exposure to third-hand smoke.

    abstract::Tobacco smoking is the major cause of many chronic diseases, especially lung cancer. Knowledge about population-wide tobacco use and exposure is essential to characterise its burden on public health and evaluate policy efficacy. Obtaining such knowledge remains challenging with current methods (e.g., surveys, biomonit...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-31324-6

    authors: Lai FY,Lympousi K,Been F,Benaglia L,Udrisard R,Delémont O,Esseiva P,Thomaidis NS,Covaci A,van Nuijs ALN

    更新日期:2018-09-05 00:00:00

  • Crepidtumines A and B, Two Novel Indolizidine Alkaloids from Dendrobium crepidatum.

    abstract::Two new indolizidine alkaloids crepidatumines A (1) and B (2) together with the stereoisomer of dendrocrepidine B (3) and known analog dendrocrepine (4) were isolated from D. crepidatum. Their structures were determined by HR-ESI-MS, NMR, and Electronic Circular Dichroism (ECD) experiments together with comparison of ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-66552-2

    authors: Xu X,Chen X,Yang R,Li Z,Zhou H,Bai Y,Yu M,Li B,Ding G

    更新日期:2020-06-12 00:00:00

  • Suicide Risk Associated with Experience of Violence and Impulsivity in Alcohol Dependent Patients.

    abstract::Alcohol dependence (AD) and aggression-impulsivity are both associated with increased suicide risk. There is a need to evaluate clinical tools in order to improve suicide risk assessment of AD patients. The present study consisted of 95 individuals with a diagnosis of AD, consecutively admitted for addiction treatment...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19373

    authors: Khemiri L,Jokinen J,Runeson B,Jayaram-Lindström N

    更新日期:2016-01-19 00:00:00

  • Oxygen vacancies promoting photoelectrochemical performance of In(2)O(3) nanocubes.

    abstract::This work reports a facile method for preparing the new photoactive In(2)O(3) films as well as their implementation in photoelectrochemical (PEC) application. We firstly investigated the relationship between oxygen vacancies (V(O)) and PEC performance and revealed a rule between them. We found that the optimized In(2)...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep01021

    authors: Gan J,Lu X,Wu J,Xie S,Zhai T,Yu M,Zhang Z,Mao Y,Wang SC,Shen Y,Tong Y

    更新日期:2013-01-01 00:00:00

  • Reprogramming to pluripotency does not require transition through a primitive streak-like state.

    abstract::Pluripotency can be induced in vitro from adult somatic mammalian cells by enforced expression of defined transcription factors regulating and initiating the pluripotency network. Despite the substantial advances over the last decade to improve the efficiency of direct reprogramming, exact mechanisms underlying the co...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-15187-x

    authors: Raab S,Klingenstein M,Möller A,Illing A,Tosic J,Breunig M,Kuales G,Linta L,Seufferlein T,Arnold SJ,Kleger A,Liebau S

    更新日期:2017-11-29 00:00:00

  • Apoptosis characterization in mononuclear blood leukocytes of HIV patients during dengue acute disease.

    abstract::Dengue virus (DENV) co-circulation in Brazil represents a challenge for treatment and vaccine development. Despite public health impact, the occurrence of coinfections with other viruses is a common event. Increased T cell activation and altered inflammatory response are found during DENV coinfection with Human Immuno...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-62776-4

    authors: Torrentes-Carvalho A,Sánchez-Arcila JC,Azamor T,Barbosa LS,Hottz ED,Gandini M,Bozza FA,da Cunha RV,de Oliveira Pinto LM,Damasco PV,de Azeredo EL

    更新日期:2020-04-14 00:00:00

  • Developing an in silico minimum inhibitory concentration panel test for Klebsiella pneumoniae.

    abstract::Antimicrobial resistant infections are a serious public health threat worldwide. Whole genome sequencing approaches to rapidly identify pathogens and predict antibiotic resistance phenotypes are becoming more feasible and may offer a way to reduce clinical test turnaround times compared to conventional culture-based m...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18972-w

    authors: Nguyen M,Brettin T,Long SW,Musser JM,Olsen RJ,Olson R,Shukla M,Stevens RL,Xia F,Yoo H,Davis JJ

    更新日期:2018-01-11 00:00:00

  • Numerical simulations of tunable ultrashort power splitters based on slotted multimode interference couplers.

    abstract::This paper presents an ultracompact tunable device for power splitting and switching by tuning the Fermi energy level of monolayer patternless graphene underneath a slotted multimode interference (MMI) coupler operating in the mid-infrared, λ = 9-11 μm. By introducing a high-index silicon slot in the central region of...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-49186-x

    authors: Huang CC,Sun TC

    更新日期:2019-09-04 00:00:00

  • Skeletal muscle cutoff values for sarcopenia diagnosis using T10 to L5 measurements in a healthy US population.

    abstract::Measurements of skeletal muscle cross-sectional area, index, and radiation attenuation utilizing clinical computed tomography (CT) scans are used in assessments of sarcopenia, the loss of skeletal muscle mass and function associated with aging. To classify individuals as sarcopenic, sex-specific cutoffs for 'low' valu...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29825-5

    authors: Derstine BA,Holcombe SA,Ross BE,Wang NC,Su GL,Wang SC

    更新日期:2018-07-27 00:00:00

  • A potent synthetic inorganic antibiotic with activity against drug-resistant pathogens.

    abstract::The acronymously named "ESKAPE" pathogens represent a group of bacteria that continue to pose a serious threat to human health, not only due to their propensity for repeated emergence, but also due to their ability to "eskape" antibiotic treatment. The evolution of multi-drug resistance in these pathogens alone has gr...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41999

    authors: Hubick S,Jayaraman A,McKeen A,Reid S,Alcorn J,Stavrinides J,Sterenberg BT

    更新日期:2017-02-06 00:00:00

  • Toll-like receptor dual-acting agonists are potent inducers of PBMC-produced cytokines that inhibit hepatitis B virus production in primary human hepatocytes.

    abstract::Recombinant interferon-α (IFN-α) treatment functionally cures chronic hepatitis B virus (HBV) infection in some individuals and suppresses virus replication in hepatocytes infected in vitro. We studied the antiviral effect of conditioned media (CM) from peripheral blood mononuclear cells (PBMCs) stimulated with agonis...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-69614-7

    authors: Janovec V,Hodek J,Clarova K,Hofman T,Dostalik P,Fronek J,Chlupac J,Chaperot L,Durand S,Baumert TF,Pichova I,Lubyova B,Hirsch I,Weber J

    更新日期:2020-07-29 00:00:00

  • Author Correction: NIHSS is not enough for cognitive screening in acute stroke: A cross-sectional, retrospective study.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-020-60584-4

    authors: Abzhandadze T,Reinholdsson M,Sunnerhagen KS

    更新日期:2020-02-27 00:00:00

  • ATHB17 enhances stress tolerance by coordinating photosynthesis associated nuclear gene and ATSIG5 expression in response to abiotic stress.

    abstract::Photosynthesis is sensitive to environmental stress and must be efficiently modulated in response to abiotic stress. However, the underlying mechanisms are not well understood. Here we report that ARABIDOPSIS THALIANA HOMEOBOX 17 (ATHB17), an Arabidopsis HD-Zip transcription factor, regulated the expression of a numbe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep45492

    authors: Zhao P,Cui R,Xu P,Wu J,Mao JL,Chen Y,Zhou CZ,Yu LH,Xiang CB

    更新日期:2017-03-30 00:00:00