Abstract:
BACKGROUND:Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the gastrointestinal tract and make up 1-2% of all gastrointestinal malignancies. Traditionally, the treatment of choice for primary disease is surgical resection; however, no single surgeon or institution gets extensive exposure to these patients so appropriate decision-making is difficult, particularly since the introduction of the tyrosine kinase inhibitor imatinib, which has become an important additional management tool. METHOD:All patients were diagnosed and treated for GISTs in Christchurch Hospital (Christchurch, New Zealand) between 1 January 2000 and 31 December 2010. We maintain a prospective database of all patients with GISTs. Data on clinical and histopathological variables, management and survival outcomes were recorded. These were then reviewed. RESULTS:There were 93 patients in this study. Fifty were women. Median age was 69 (interquartile range (IQR) 59-76) years. Fifty-one tumours were located in the stomach, 27 in the small bowel, six in the colon, three in the oesophagus, one in the rectum and five were extra-gastrointestinal. In total, 22 patients received imatinib therapy; four patients with metastatic disease had imatinib as sole therapy. The median follow-up was 58 (IQR 30-90) months. The 5-year overall survival and disease-free survival (DFS) for the entire study population was 69% and 64%, respectively. The 5-year DFS was higher for all patients who have localized disease when compared with those who have metastatic disease (76% versus 28%, P-value 0.001). CONCLUSION:Surgery aiming at an R0 resection remains the mainstay of treatment. We propose the most effective way to grow the knowledge base in New Zealand is the establishment of a national register, thereby allowing better clinical decision-making by interpretation of a larger data set.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Siu J,Lim M,Fischer J,Dobbs B,Wakeman C,Ing A,Frizelle Fdoi
10.1111/ans.12429subject
Has Abstractpub_date
2016-03-01 00:00:00pages
162-6issue
3eissn
1445-1433issn
1445-2197journal_volume
86pub_type
杂志文章abstract:AIM:To identify the outcome of laparoscopic revision of gastric band surgery with respect to percentage of excess weight lost (%EWL). METHODS:Analysis of a prospective database was then performed and %EWL was plotted with respect to time from initial procedure and also time from revision procedure. RESULTS:All revisi...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2009.05088.x
更新日期:2010-05-01 00:00:00
abstract:AIM:To establish a proinflammatory cytokine profile of the cerebrospinal fluid (CSF) following trauma. BACKGROUND:Trauma is associated with a postinjury syndrome consisting of loss of weight and nitrogen, pyrexia, anorexia and fatigue. It has been proposed that cytokines are pathophysiologically involved in this syndr...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03530.x
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Urgent assessment of haematuria is critical to exclude malignancy. The objective of this study is to report the outcomes of the first 3 years of a dedicated haematuria clinic at the Royal Melbourne Hospital, a Victorian tertiary hospital. METHODS:All patients assessed in the haematuria clinic from April 201...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12742
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Implant-based breast reconstruction is becoming increasingly popular because of the widespread adoption of acellular dermal matrix (ADM), which allows surgeons to obtain good aesthetic results with fewer operations. To develop more conservative surgical techniques, a retrospective, three-centre, proof-of-con...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12849
更新日期:2017-06-01 00:00:00
abstract::In the early years of the introduction of Christianity into China, one American medical missionary distinguished himself by his kindness and generosity towards the Chinese people, and also by his surgical prowess. Peter Parker (1804-1888) was a graduate from the Yale University Medical School and was also an ordained ...
journal_title:ANZ journal of surgery
pub_type: 传,历史文章,杂志文章
doi:10.1111/ans.12402
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:To examine any geographical variation in the management of urolithiasis amongst the Australian states and territories. METHODS:Retrospective study with data obtained from the Medicare Australia database, the Royal Australasian College of Surgeons and the Urological Society of Australia and New Zealand. RES...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13646
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Perioperative hypothermia occurs frequently and can have serious health-related and financial consequences. Despite multiple warming methods available, perioperative hypothermia remains prevalent. To be effective, preventative measures must be timely and target patients most at risk. The aim of this retrospe...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12369
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Evidence suggests that there is considerable variation in the types of procedures used to treat cancer. This variation may result in suboptimal or cost-ineffective care. The present study examined the variation in surgical treatment of melanoma before the establishment of a Melanoma Network that could promot...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03717.x
更新日期:2006-05-01 00:00:00
abstract::Gluteal compartment syndrome is uncommon and is often diagnosed late, resulting in muscle necrosis and sciatic nerve palsy. The mainstay of treatment is prompt diagnosis and early surgery. A high index of suspicion is essential, especially in the setting of major bleeding and excessive pain. Embolization and hyperbari...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03797.x
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:The objective of the research was to validate our results on sentinel lymph node biopsy (SLNB) and to determine factors affecting false-negative (FN) rates of SLNB in Chinese patients with invasive breast cancers. METHODS:A retrospective study of patients with clinically node-negative invasive breast cancer...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04260.x
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Patients with centrally located tumours involving the nipple-areolar complex (NAC) who undergo breast-conserving treatment (BCT) are at high risk for breast deformity and asymmetry. Immediate oncoplastic breast reconstruction (OBR) can have a favourable impact on surgical outcome. METHODS:We retrospectively...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15078
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Patients taking warfarin are often given interim anticoagulation in the perioperative period. Institutional guidelines that use low-molecular-weight heparin (LMWH) 'bridging' while the international normalized ratio (INR) is sub-therapeutic are often based on the American College of Chest Physicians Anticoag...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12070
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:There is increasing evidence that uncomplicated acute diverticulitis (UAD) can be safely and effectively managed as an outpatient. The aim of the current study was to evaluate if an early computed tomography (CT) scan in the emergency department (ED) can reduce the number of hospital admissions when UAD is d...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15285
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Use and techniques of oesophageal replacement for long gap oesophageal atresia are still evolving. Gastric tube graft interposition as an oesophageal substitute was evaluated on an animal model. METHODS:Twenty-three postweaned, 28-day-old-piglets were used as the experimental animals. Isoperistaltic gastric...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1440-1622.2001.02023.x
更新日期:2001-01-01 00:00:00
abstract::It was the achievement of Andreas Vesalius (1514-1564) to redefine the understanding of human anatomy; and that of Homer was to write the first historical novel. This paper offers a link between the works of these two venturers, by way of an examination of the clinical anatomy of the clavicle. ...
journal_title:ANZ journal of surgery
pub_type: 传,历史文章,杂志文章
doi:10.1111/j.1445-2197.2011.05711.x
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Worldwide, the evolution of management of liver injury has resulted in improved outcomes. The aim of this study was to examine the trend in the management and outcomes of patients with liver injury. Primary outcomes were defined as mortality and hospital length of stay. The secondary aim was to identify inde...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13248
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Optimal management of regional lymph nodes for thin cutaneous melanoma is uncertain. We evaluated regional lymph node involvement and 5-year melanoma-specific survival (MSS) in patients with thin (≤1 mm) primary melanoma. METHODS:Patients with a melanoma, American Joint Committee on Cancer Staging 8th Editi...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15804
更新日期:2020-04-01 00:00:00
abstract::Adenoid cystic carcinoma of the trachea, although rare, is the second most common primary tumour of the trachea. It is a slow-growing tumour found in younger patients than the more common squamous cell carcinoma and is relatively resistant to treatment, but metastasizes late in the course of disease and even in unrese...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03848.x
更新日期:2006-08-01 00:00:00
abstract::About 50% of the trauma victims die at the scene mostly because of exsanguinating haemorrhage. Most trials of resuscitation fail in face of the ongoing bleeding. Ongoing research/studies to save these victims by inducing rapid hypothermia using cardiopulmonary bypass as an emergency initial measure along with delayed ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.14313
更新日期:2018-07-01 00:00:00
abstract:INTRODUCTION:Baseline measurements are an essential component of clinical trials. They should establish that the groups involved are clinically equivalent so that any observed differences can be attributed to the intervention under evaluation. The objective of this study was to review the use of baseline comparisons in...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1046/j.1445-2197.2002.02476.x
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate the correlation between serum albumin level change (ΔALB) and post-operative complications in patients with normal preoperative serum albumin after gastrectomy of gastric cancer. METHODS:A total of 193 patients undergoing curative (R0) gastrectomy from September 201...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15363
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:The aim of this project was to increase rates of day surgery, reduce elective surgical waiting lists, give patients a guaranteed date of surgery and improve operating theatre utilization. The guiding principle behind the project was to treat the administration of elective surgery as a separate business unit,...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03526.x
更新日期:2005-09-01 00:00:00
abstract::With the widespread use of abdominal imaging, the detection and therefore incidence of adrenal tumours is increasing. The laparoscopic approach to primary surgical resection of adrenal tumours has now become the standard of care. There is scarce published literature regarding the management and outcomes of recurrent a...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2009.04892.x
更新日期:2009-05-01 00:00:00
abstract::This paper examines the career of Johann Sebastian Bach (1685-1750) and the role played by Wilhelm His I (who was, with Albert von Haller, a noted pioneer of physiology) in the exhumation of Bach's remains in 1894. His's examination of these remains allowed the sculptor Carl Seffner to produce the celebrated statue of...
journal_title:ANZ journal of surgery
pub_type: 传,历史文章,杂志文章
doi:10.1111/ans.12398
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:In the present paper we describe the presentation and management of ductal carcinoma in situ (DCIS) of the breast in women in Australia in 1995. This representative, national data set provides a historical comparator for studies examining DCIS management that follow. METHODS:Surgeons identified by populatio...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2002.02532.x
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:The ability to predict the behaviour of breast cancer from its dimensions allows the clinician to inform a woman about the absolute benefits of adjuvant therapies or further surgery to control her disease. Tumour size and grade are independent predictors of nodal disease. This study aims to generate a tool, ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03918.x
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Late laparoscopic cholecystectomy (LC) after endoscopic retrograde cholangiopancreatography (ERCP) and sphincterotomy (ES) for common bile duct (CBD) stone clearance, two-stage LC (TSLC), is associated with difficult surgical dissection and an increased rate of conversion to open procedure. The purpose of th...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12967
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Despite conflicting data regarding oncological outcomes, studies demonstrate that complete mesocolic excision (CME) and central vascular ligation (CVL) for right-sided colon cancer removes significantly more tissue and yields higher lymph node counts when compared to conventional resection. This study aims t...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.16224
更新日期:2020-08-11 00:00:00
abstract::Total thyroidectomy is the treatment of choice for clinically significant papillary thyroid cancer (PTC); however, 10-15% develop palpable local recurrence in the cervical lymph nodes. Metastases in the cervical lymph nodes account for 75% of loco-regional recurrence and up to 50% of these patients eventually die of t...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04019.x
更新日期:2007-04-01 00:00:00
abstract::In the seventeenth century, Holland and the allied provinces of the northern Netherlands won final independence from their Spanish overlords and formed a worldwide economic empire. Dutch ships dominated the seas from the Caribbean to Japan and reconnoitred the coasts of Australia and New Zealand. Dutch society was cos...
journal_title:ANZ journal of surgery
pub_type: 传,历史文章
doi:10.1111/j.1445-2197.2007.04327.x
更新日期:2007-12-01 00:00:00