Abstract:
BACKGROUND:Insulin pumps (for continuous subcutaneous insulin infusion [CSII]) are used widely in type 1 diabetes mellitus. Although there has been considerable study of outcomes, there are few recent data on CSII-associated adverse events and no data on family perceptions of adverse events and their confidence in dealing with them. SUBJECTS AND METHODS:We approached all families of children and adolescents ≤ 19 years of age on CSII attending the diabetes clinic over a 16-week clinic cycle. Participants completed a retrospective questionnaire examining issues over the previous 12 months. Data on pump adverse events as well as answers to questions pertaining to education and confidence were collected. RESULTS:Our survey received a response rate of 99%, with 235 of the 238 families approached participating. In the preceding 12 months, 104 of 230 (45%) had reported at least one pump-related adverse event (either mechanical or set-related), with an associated 52 of 229 (23%) resulting in pump replacement. This equated to a minimum incidence density of 53 adverse events/100 person-years. Additionally, 18 of 230 (8%) reported a hospital admission or emergency department attendance as a consequence. Pump malfunction and infusion set/site failures were the most common events reported, with one or more events in 58 of 104 (56%) and 47 of 104 (45%), respectively. Adverse events, excluding set/site failures, were associated with older age (13.1 ± 3.4 years vs. 11.9 ± 4 years; P = 0.02). CONCLUSIONS:This is the first study to look at family perceptions of adverse events while using modern CSII. It highlights a high self-reported rate of CSII-related adverse events, pump replacement, and subsequent presentation to the hospital. Potential areas for additional targeted education are identified. Further prospective study examining pump adverse event characteristics and incidence is warranted.
journal_name
Diabetes Technol Therjournal_title
Diabetes technology & therapeuticsauthors
Wheeler BJ,Donaghue KC,Heels K,Ambler GRdoi
10.1089/dia.2013.0315subject
Has Abstractpub_date
2014-04-01 00:00:00pages
204-7issue
4eissn
1520-9156issn
1557-8593journal_volume
16pub_type
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journal_title:Diabetes technology & therapeutics
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journal_title:Diabetes technology & therapeutics
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章,评审
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章
doi:10.1089/152091502760306544
更新日期:2002-01-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章,评审
doi:10.1089/15209150260007381
更新日期:2002-01-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 临床试验,杂志文章
doi:10.1089/15209150152811207
更新日期:2001-01-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1089/dia.2010.0111
更新日期:2010-12-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2010-10-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 临床试验,杂志文章
doi:10.1089/152091502320798213
更新日期:2002-01-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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更新日期:2006-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-09-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 临床试验,杂志文章,多中心研究
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更新日期:2007-06-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章
doi:10.1089/dia.2009.0121
更新日期:2010-03-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章
doi:10.1089/dia.2009.0100
更新日期:2010-02-01 00:00:00
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pub_type: 临床试验,杂志文章
doi:10.1089/dia.2005.7.124
更新日期:2005-02-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 临床试验,杂志文章
doi:10.1089/dia.2008.0079
更新日期:2008-10-01 00:00:00
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journal_title:Diabetes technology & therapeutics
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1089/dia.2013.0056
更新日期:2013-08-01 00:00:00