A single nucleotide polymorphism in the dopamine receptor D2 gene may be informative for resistance to fescue toxicosis in angus-based cattle.

Abstract:

:Fescue toxicosis (FT) reduces beef animal growth and fertility. Animals afflicted with FT typically have decreased circulating prolactin concentrations and thicker summer hair coats. Preliminary experiments examined the informativeness of a novel Dopamine Receptor 2 (DRD2) G/A SNP for resistance to FT. Steers grazed tall fescue containing a toxic (E+) or non-toxic (NTE) strain of endophyte. Decreased serum prolactin concentrations were observed in GG steers in May compared to AA steers when grazing E+ pastures (P < 0.02). In a second study, GG steers had decreased prolactin concentrations (P = 0.004) and increased hair coat scores (P = 0.01) relative to AA steers when grazing E+ pastures. Allele and genotypic frequencies were different (P = 0.016 and 0.026, respectively) between spring-calving and fall-calving herds grazing E+ pastures, such that the A allele and the AA genotype were more prevalent in spring-calving herds, suggesting active selection for the A allele. Regardless of calving season, AA heifers tended toward fewer days to first calf (733.6 ± 4.4 d) than did GG heifers (756.6 ± 9.2 days; P = 0.055). These results suggest that the DRD2 SNP may have use in selecting animals resistant to FT.

journal_name

Anim Biotechnol

journal_title

Animal biotechnology

authors

Campbell BT,Kojima CJ,Cooper TA,Bastin BC,Wojakiewicz L,Kallenbach RL,Schrick FN,Waller JC

doi

10.1080/10495398.2013.796960

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

1-12

issue

1

eissn

1049-5398

issn

1532-2378

journal_volume

25

pub_type

杂志文章
  • Biomedical applications of ovarian transvaginal ultrasonography in cattle.

    abstract::Ovarian transvaginal ultrasonography (OTU) has been used world-wide for commercial ovum pick-up programs for in vitro embryo production in elite herds, providing an excellent model for the elucidation of factors controlling bovine oocyte developmental competence. Noninvasive sampling and treatment of ovarian structure...

    journal_title:Animal biotechnology

    pub_type: 杂志文章,评审

    doi:10.1080/10495398.2013.870075

    authors: Velazquez MA,Kues WA,Niemann H

    更新日期:2014-01-01 00:00:00

  • Comparative pharmacokinetic study of two kinds of altrenogest oral solutions for sows.

    abstract::This study was to compare the pharmacokinetic characteristics of domestic altrenogest oral solution (DAOS) or imported altrenogest oral solution (IAOS) in healthy sows. A single administration (1 mg/kg body weight) of DAOS or IAOS was performed in sixteen healthy sows according to a two-period crossover design. Plasma...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2020.1723608

    authors: Li Y,Yang H,Xia L,Wang S,Bu S

    更新日期:2020-03-17 00:00:00

  • Mutations in Leptin (LEP) Gene Are Associated with Carcass and Meat Quality Traits in Crossbreed Rabbits.

    abstract::Leptin is a hormone synthesized and secreted primarily in adipose cells that help to regulate energy balance. This study examined the associations of single nucleotide polymorphisms in the rabbit leptin gene with growth traits, slaughter traits and physicochemical parameters of New Zealand White (NZW) and Belgian Gian...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2017.1347881

    authors: Migdal L,Koziol K,Palka S,Migdal W,Zabek T,Otwinowska-Mindur A,Migdal A,Kmiecik M,Maj D,Bieniek J

    更新日期:2018-04-03 00:00:00

  • Stage specific expression of ATP-binding cassette and solute carrier superfamily of transporter genes in mammary gland of riverine buffalo (Bubalus bubalis).

    abstract::In the present study, expression level of various ATP-binding cassette (ABC) viz., ABCA1, ABCA7, ABCG1, ABCG2, and ABCG5; associated transcription factors viz., SREBF1, LXRα (NR1H3), PPARA, and Solute Carriers (SLC); or Glucose transporters (GLUT) viz., SLC2A1(GLUT1), SLC2A4 (GLUT4), SLC2A8 (GLUT8), and SLC2A12 (GLUT1...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2013.839949

    authors: Sharma A,Aggarwal J,Sodhi M,Kishore A,Mishra BP,Mohanty AK,Kataria RS,Kaushik JK,Mukesh M

    更新日期:2014-01-01 00:00:00

  • Analysis of association between the MUC4 g.8227C>G polymorphism and production traits in Italian heavy pigs using a selective genotyping approach.

    abstract::In pigs, susceptibility to enterotoxigenic Escherichia coli (ETEC) K88 strains (locus F4bcR) is determined by a dominant allele, with the recessive allele determining resistance. The susceptible allele also appeared to be associated with higher growth rate even with discordant results. A single nucleotide polymorphism...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2011.653462

    authors: Fontanesi L,Bertolini F,Dall'Olio S,Buttazzoni L,Gallo M,Russo V

    更新日期:2012-01-01 00:00:00

  • Effects of Recombinant Human Lactoferrin on Osteoblast Growth and Bone Status in Piglets.

    abstract::Lactoferrin (LF), an ~80 kDa iron-binding glycoprotein, modulates many biological effects, including antimicrobial and immunomodulatory activities. Recently, it was shown that LF also regulates bone cell activity, suggesting its therapeutic effect on postmenopausal bone loss. However, a minimal amount is known regardi...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2017.1313269

    authors: Li Q,Zhao J,Hu W,Wang J,Yu T,Dai Y,Li N

    更新日期:2018-04-03 00:00:00

  • Effects of microbial feed additives on feed utilization and growth performance in growing Barki lambs fed diet based on peanut hay.

    abstract::The effects of supplementing diet of growing lambs with microbial feed additive mixture (direct-fed microbial; DFM) based on Saccharomyces cerevisiae, lactic acid bacteria and exogenous enzymes on feed intake, nutrient digestibility, nitrogen (N) utilization, ruminal fermentation, blood chemistry and growth performanc...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2019.1616554

    authors: Sallam SMA,Kholif AE,Amin KA,El-Din ANMN,Attia MFA,Matloup OH,Anele UY

    更新日期:2020-10-01 00:00:00

  • FTO Promotes Adipogenesis through Inhibition of the Wnt/β-catenin Signaling Pathway in Porcine Intramuscular Preadipocytes.

    abstract::Numerous studies have demonstrated that FTO plays an important role in adipogenesis. Herein, we designed a small interfering RNA targeting FTO to knock down its endogenous expression and investigated its effects on the proliferation and differentiation of porcine intramuscular preadipocytes. Its possible mechanism was...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2016.1273835

    authors: Chen X,Luo Y,Jia G,Liu G,Zhao H,Huang Z

    更新日期:2017-10-02 00:00:00

  • Genomic organization and promoter analysis of the bovine ADAM12 gene.

    abstract::A disintegrin and metalloprotease (ADAM) 12 is a member of the ADAM family possessing a putative role in a variety of biological processes such as modulation of proteolytic processing, cell adhesion, cell fusion, and signaling. Recently, it has been suggested that ADAM12 is involved in regulation of adipogenesis as we...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495390802212445

    authors: Taniguchi Y,Doronbekov K,Yamada T,Sasaki Y,Takano A,Sugimoto Y

    更新日期:2008-01-01 00:00:00

  • Harvesting the genomic promise: recombineering sequences for phenotypes.

    abstract::The past decade has witnessed the construction of linkage and physical maps defining quantitative trait loci (QTL) in various domesticated species. Targeted chromosomal regions are being further characterized through the construction of bacterial artificial chromosome (BAC) contigs in order to isolate and characterize...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1081/ABIO-120026481

    authors: Rogatcheva MB,Rund LA,Beever JE,Schook LB

    更新日期:2003-11-01 00:00:00

  • Evaluation of Bovine High-Density SNP Genotyping Array in Indigenous Dairy Cattle Breeds.

    abstract::In total 52 samples of Sahiwal ( 19 ), Tharparkar ( 17 ), and Gir ( 16 ) were genotyped by using BovineHD SNP chip to analyze minor allele frequency (MAF), genetic diversity, and linkage disequilibrium among these cattle. The common SNPs of BovineHD and 54K SNP Chips were also extracted and evaluated for their perform...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2017.1329150

    authors: Dash S,Singh A,Bhatia AK,Jayakumar S,Sharma A,Singh S,Ganguly I,Dixit SP

    更新日期:2018-04-03 00:00:00

  • Molecular Characterization of Equine APRIL and its Expression Analysis During the Adipogenic Differentiation of Equine Adipose-Derived Stem Cell In Vitro.

    abstract::A proliferation inducing ligand (APRIL) is a member of the TNF superfamily. It shares two receptors with B-cell activating factor (BAFF), B-cell maturation antigen (BCMA), and transmembrane activator and CAML interactor (TACI). Herein, the equine APRIL was identified from equine adipose-derived stem cell (ASC), and th...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2016.1182540

    authors: Wu H,Bi X,Cao F,Zhu C,Liu H,Song J,Ma L,Ma L,Zhang Y,Zhao D,Liu H,Xu X,Zhang S

    更新日期:2016-10-01 00:00:00

  • Characterization of a normalized cDNA library from bovine intestinal muscle and epithelial tissues.

    abstract::Tissue-specific cDNA library sequences (expressed sequence tags, or EST) yield a detailed snapshot of gene expression and are useful in developing second-generation molecular resources (i.e., microarrays) for gene expression profiling. The objective of this study was to develop and characterize an intestine-specific c...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1081/abio-200053398

    authors: Baumann RG,Baldwin RL,Van Tassell CP 6th,Sonstegard TS,Matukumalli LK

    更新日期:2005-01-01 00:00:00

  • Isolation of thirty-one new porcine microsatellites from a microsatellite enriched microdissected chromosome 8 library.

    abstract::Chromosome 8 (SSC8) is an important one in the swine genome because it has been shown to harbor several economically important quantitative trait loci (QTL). The entire porcine chromosome 8 was microdissected and amplified by degenerate oligonucleotide primer (DOP) PCR. The PCR product was then enriched for (CA)n micr...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495390009525945

    authors: Wang Z,Rohrer G,Stone R,Troyer D

    更新日期:2000-01-01 00:00:00

  • Growth, immunity, relative gene expression, carcass traits and economic efficiency of two rabbit breeds fed prebiotic supplemented diets.

    abstract::The current study designed to evaluate the effect of oligosaccharide supplemented diets on growth performance, histomorphometric changes, economic efficiency and genetic expression of some growth and immunity-relative genes. One hundred and twenty weaned male rabbits, six weeks of age of two breeds (NZW and APPRI) wer...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2020.1800485

    authors: Abd El-Aziz AH,El-Kasrawy NI,Abd El-Hack ME,Kamel SZ,Mahrous UE,El-Deeb EM,Atta MS,Amer MS,Naiel MAE,Khafaga AF,Metwally AE,Abo Ghanima MM

    更新日期:2020-07-31 00:00:00

  • A cloned pig model for examining atherosclerosis induced by high fat, high cholesterol diets.

    abstract::The pig is a recognized model for the onset of coronary heart disease and heart attacks. Previous studies have shown that serum cholesterol levels in the pig can be elevated using a high fat, high cholesterol (HFHC) diet. What has been lacking is a genetically defined model corresponding to human ApoE4 susceptibility ...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2010.490693

    authors: Jensen TW,Mazur MJ,Pettigew JE,Perez-Mendoza VG,Zachary J,Schook LB

    更新日期:2010-07-01 00:00:00

  • Metabolome fingerprints, performance and carcass quality of beef calves supplemented with antibiotic free additive.

    abstract::The aim of this study was to investigate the effects of probiotics on pre-weaning performance, muscle, and fat deposition and serum metabolite profiles in male and female Senepol calves. Thirty new-born Senepol calves, 15 males and 15 females, were randomly allocated to the following treatments: CON a control group th...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2020.1828095

    authors: Gandra JR,Pedrini CA,Cônsolo NRB,Acosta AP,Seno LO,Barbosa LCGS,Noia IZ,Buarque VLM,Padilla ARH,Colnago LA,Gandra ERS

    更新日期:2020-10-06 00:00:00

  • Beneficial and adverse effects of medicinal plants as feed supplements in poultry nutrition: a review.

    abstract::Medicinal plants exhibit colossal impact on poultry industries by improving its performance and productivity. However, some of these plants show adverse influence too by decreasing egg production percentage, egg mass, and microbiota counts. Green tea, nettle, pennyroyal, yarrow, and alfalfa in the form of seed, powder...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2020.1798973

    authors: Pliego AB,Tavakoli M,Khusro A,Seidavi A,Elghandour MMMY,Salem AZM,Márquez-Molina O,Rene Rivas-Caceres R

    更新日期:2020-08-03 00:00:00

  • Investigation of tissue-specific human orthologous alternative splice events in pig.

    abstract::Alternative splicing of pre-mRNA can contribute to differences between tissues or cells either by regulating gene expression or creating proteins with various functions encoded by one gene. The number of investigated alternative splice events in pig has so far been limited. In this study we have investigated alternati...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2010.497729

    authors: Nygard AB,Jørgensen CB,Cirera S,Fredholm M

    更新日期:2010-10-01 00:00:00

  • Evaluation of real-time PCR as an alternative for potency testing of Brucella abortus vaccines.

    abstract::The aim of the research was to evaluate real-time PCR (qPCR) as an alternate method for quantitative detection of Brucella abortus strain 544 (S544) in the spleen of mice for potency testing of live B. abortus strain 19 (S19) vaccine. IS711 and eryC gene-based qPCR were optimized for calculating copy number. The copy ...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2020.1735404

    authors: Gupta T,Rawat M,Kumar B,Varshney R,Chakravarti S,Qureshi S

    更新日期:2020-04-02 00:00:00

  • The expression and regulation of miR-1 in goat skeletal muscle and satellite cell during muscle growth and development.

    abstract::MicroRNA-1 (miR-1) has been shown to play an important role in muscle growth and development, however, it was mainly discovered in model animals. To explore the function and mechanism of miR-1 in goat, we firstly explored the expression profile of miR-1 in goat tissues and cells. Furthermore, the target gene of miR-1 ...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2019.1622555

    authors: Sui M,Zheng Q,Wu H,Zhu L,Ling Y,Wang L,Fang F,Liu Y,Zhang Z,Chu M,Zhang Y

    更新日期:2020-10-01 00:00:00

  • Molecular Characterization, Polymorphism, and Association of Porcine GADD45G Gene.

    abstract::Growth arrest and DNA-damage-inducible gamma (GADD45G) is a reproduction related gene. In this study, the full-length cDNA sequence of porcine GADD45G gene was cloned through rapid amplification of cDNA ends (RACE) method. The porcine GADD45G gene encodes a protein of 159 amino acids that shares high homology with the...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2015.1005216

    authors: Liu C,Zhang W,Yang D,Liu Y

    更新日期:2015-01-01 00:00:00

  • Expressional and Bioinformatic Analysis of Bovine Filia/Ecat1/Khdc3l Gene: A Comparison with Ovine Species.

    abstract::Maternal effect genes have highly impressive effects on pre-implantation development. Filia/Ecat1/Khdc3l is a maternal effect gene found in mouse oocytes and embryos, loss of which causes a 50% decrease in fertility. In the present study, we investigated Filia mRNA expression in bovine oviduct, 30- to 40-day fetus, li...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2016.1157081

    authors: Zahmatkesh A,Ansari Mahyari S,Daliri Joupari M,Rahmani H,Shirazi A,Amiri Roudbar M,Ansari Majd S

    更新日期:2016-01-01 00:00:00

  • Identification of piRNAs in the testes of Sunite and Small-tailed Han sheep.

    abstract::P-element-induced wimpy testis-interacting RNAs (piRNAs) are small RNAs that are essential for mammalian spermatogenesis and testicular development. Comparative analyses of the molecular mechanisms of spermatogenesis among different organisms are therefore dependent on accurate piRNA characterizations. In this study, ...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2019.1640717

    authors: He X,Li B,Fu S,Wang B,Qi Y,Da L,Te R,Sun S,Liu Y,Zhang W

    更新日期:2019-07-18 00:00:00

  • Screening and scanning of single nucleotide polymorphisms in the pig melanocortin 1 receptor gene (MC1R) by pyrosequencing.

    abstract::The increasing interest in the discovery and characterization of single nucleotide polymorphisms (SNPs) emphasis the need for high-throughput and cost effective scoring methods. Pyrosequencing is a novel method for screening SNPs. In this study we examine breed specific SNPs in the pig melanocortin 1 receptor gene (MC...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1081/ABIO-100108341

    authors: Gustafsson AC,Kijas JM,Alderborn A,Uhlén M,Andersson L,Lundeberg J

    更新日期:2001-11-01 00:00:00

  • Candidate gene approach: potentional association of caspase-1, inhibitor of apoptosis protein-1, and prosaposin gene polymorphisms with response to Salmonella enteritidis challenge or vaccination in young chicks.

    abstract::Salmonella enteritidis (SE) contamination of poultry products is a major cause of foodborne disease worldwide. Caspase-1 and inhibitor of apoptosis protein-1 (IAP-1) were selected as candidate genes for chicken response to SE because their proteins play critical roles in the apoptotic pathway when intracellular bacter...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1081/ABIO-120022136

    authors: Liu W,Lamont SJ

    更新日期:2003-05-01 00:00:00

  • Interferon-alpha genes from Bos and Bubalus bubalus.

    abstract::Interferon-a genes were cloned from six breeds of three species of two genera (three Chinese native cattle breeds of yellow cattle, wild yak and HuanHu domestic yak, one European breed of Holstein cow, and two water buffalo breeds of FuAn water buffalo and FuZhong water buffalo) by direct PCR. The PCR products were di...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495390500461104

    authors: Shi X,Xia C,Pan B,Wang M

    更新日期:2006-01-01 00:00:00

  • Temporal microRNA expression profile of pig peripheral blood during postnatal development.

    abstract::Gene expression profiles of blood can reflect the physiopathologic status of the immune system. The dynamic microRNA (miRNA) expression profiles of peripheral blood from pigs at different developmental stages, and how differential expression of miRNAs might relate to immune system development, are unknown. In this stu...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2020.1824920

    authors: Zhong Z,Zhu X,Tang Q,Hong L,Gu Y,He Z,Tao X,Yang X,Liang Y,Shen L,Tan Y,Zeng K,Ying S,Yang Y,Lei Y,Wang Y,Gong J,Chen X,Zhou R,Zhu L,Lv X

    更新日期:2021-01-18 00:00:00

  • Lipopolysaccharide binding protein/CD14/ TLR4-dependent recognition of salmonella LPS induces the functional activation of chicken heterophils and up-regulation of pro-inflammatory cytokine and chemokine gene expression in these cells.

    abstract::Lipopolysaccharide (LPS) is the major pathogen-associated molecular pattern (PAMP) found in the cell wall of gram-negative bacteria and, in mammals, is recognized by the Toll-like receptor 4 (TLR4) in conjunction with the serum protein, lipopolysaccharide-binding protein (LBP), and the CD14 co-receptor. We have found ...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495390500264896

    authors: Kogut MH,He H,Kaiser P

    更新日期:2005-01-01 00:00:00

  • Subcellular Localization and Polymorphism of Bovine FABP4 in Bovine Intramuscular Adipocytes.

    abstract::Fatty acid binding protein 4 (FABP4) I74 V, a gene polymorphism associated with unsaturated fatty acid contents, was discovered in Japanese Black cattle. Individuals with FABP4 I/I genotype contain a significantly high level of palmitoleic acid compared to those with FABP4 V/V genotype. It remains unknown how the FABP...

    journal_title:Animal biotechnology

    pub_type: 杂志文章

    doi:10.1080/10495398.2015.1102148

    authors: Yonekura S,Hirota S,Miyazaki H,Tokutake Y

    更新日期:2016-01-01 00:00:00