DeNovoGUI: an open source graphical user interface for de novo sequencing of tandem mass spectra.

Abstract:

:De novo sequencing is a popular technique in proteomics for identifying peptides from tandem mass spectra without having to rely on a protein sequence database. Despite the strong potential of de novo sequencing algorithms, their adoption threshold remains quite high. We here present a user-friendly and lightweight graphical user interface called DeNovoGUI for running parallelized versions of the freely available de novo sequencing software PepNovo+, greatly simplifying the use of de novo sequencing in proteomics. Our platform-independent software is freely available under the permissible Apache2 open source license. Source code, binaries, and additional documentation are available at http://denovogui.googlecode.com .

journal_name

J Proteome Res

authors

Muth T,Weilnböck L,Rapp E,Huber CG,Martens L,Vaudel M,Barsnes H

doi

10.1021/pr4008078

subject

Has Abstract

pub_date

2014-02-07 00:00:00

pages

1143-6

issue

2

eissn

1535-3893

issn

1535-3907

journal_volume

13

pub_type

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