Welcome to the Journal of Comparative Effectiveness Research.

abstract：AIMS:To analyze administrative claims data from Medicaid, Medicare and commercial insurance sources to estimate stroke risk, bleeding risk, and the use of antithrombotic treatment in patients with atrial fibrillation (AF). METHODS:Included patients were aged ≥18 years with a new or existing diagnosis of AF. Outcomes w...

journal_title：Journal of comparative effectiveness research

authors： Lang K,Federico V,Patel AA,Munsell M,Nelson WW,Owens G,Mody SH,Schein J,Menzin J

更新日期：2016-01-01 00:00:00

abstract：:Aim: Dedicated brain imaging is advocated by the National Comprehensive Cancer Network guidelines for newly diagnosed non-small-cell cancer (NSCLC) patients beyond stage I. The current study assessed the performance characteristics of this recommendation. Methods: Through accessing the Surveillance, Epidemiology and E...

journal_title：Journal of comparative effectiveness research

authors： Abdel-Rahman O

更新日期：2019-06-01 00:00:00

abstract：:Alternative approaches to the current rebate system are being considered by policymakers and stakeholders in the private insurance market. This paper presents an analysis of three alternative options to the current rebate model: retaining retroactive rebates but requiring 100% pass-through of rebates and fees to plan ...

journal_title：Journal of comparative effectiveness research

authors： Pearson SD,Segel C,Cole A,Henshall C,Towse A

更新日期：2019-10-01 00:00:00

abstract：AIM:To evaluate overall survival (OS) in unresectable American Joint Committee on Cancer (AJCC) stage I/II hepatocellular carcinoma (HCC) treated with drug-eluting-bead transarterial chemoembolization (DEB-TACE) versus best supportive care. MATERIALS & METHODS:OS in consecutive patients with AJCC stage I/II unresectab...

journal_title：Journal of comparative effectiveness research

authors： Xing M,Kokabi N,Prajapati HJ,Close O,Ludwig JM,Kim HS

更新日期：2016-03-01 00:00:00

abstract：:Aim: Increasing use of selective serotonin-reuptake inhibitors (SSRIs) in Scotland, coupled with safety concerns with some SSRIs, and the increasing availability of generic SSRIs, have resulted in multiple initiatives to improve the quality and efficiency of their prescribing in Scotland. Our aim is to assess their in...

journal_title：Journal of comparative effectiveness research

authors： Godman B,Kurdi A,McCabe H,Johnson CF,Barbui C,MacBride-Stewart S,Hurding S,Leporowski A,Bennie M,Morton A

更新日期：2019-05-01 00:00:00

abstract：AIM:Details of data quality and how quality issues were solved have not been reported in published comparative effectiveness studies using electronic health record data. METHODS:We developed a conceptual framework of data quality assessment and preprocessing and apply it to a study comparing angiotensin-converting enz...

journal_title：Journal of comparative effectiveness research

authors： Huang Y,Voorham J,Haaijer-Ruskamp FM

更新日期：2016-07-01 00:00:00

abstract：:Aim: Breast cancer is a leading cause of cancer among women. Because guidelines on screening for breast cancer for certain ages are controversial, many experts advocate the use of shared decision making (SDM) using validated decision aids (DAs). Recent studies have concluded that DAs are beneficial; however, the resul...

journal_title：Journal of comparative effectiveness research

authors： Yu L,Li P,Yang S,Guo P,Zhang X,Liu N,Wang J,Zhang W

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Palliative cancer patients often require clinic or hospital follow-up after any treatment intervention they may have received. This is typically done in person at either a hospital or a clinic. In these advanced cancer patients, this may be burdensome and result in attrition. Telephone follow-up is becoming ...

journal_title：Journal of comparative effectiveness research

authors： Zhou M,Holden L,Bedard G,Zeng L,Lam H,Chu D,Lao N,Lauzon N,Chow E

更新日期：2012-11-01 00:00:00

abstract：:Translation of medical evidence into practice has not kept pace with the growth of medical technology and knowledge. We present three case studies--statins, drug eluting stents and bone marrow transplantation for breast cancer--to propose a framework for describing five factors that may influence the rate of adoption....

journal_title：Journal of comparative effectiveness research

authors： Dubois RW,Lauer M,Perfetto E

更新日期：2013-07-01 00:00:00

abstract：AIM:Current stroke severity scales cannot be used for archival data. We develop and validate a measure of stroke severity at hospital discharge (Stroke Administrative Severity Index [SASI]) for use in billing data. METHODS:We used the NIH Stroke Scale (NIHSS) as the theoretical framework and identified 285 relevant In...

journal_title：Journal of comparative effectiveness research

authors： Simpson AN,Wilmskoetter J,Hong I,Li CY,Jauch EC,Bonilha HS,Anderson K,Harvey J,Simpson KN

更新日期：2018-04-01 00:00:00

abstract：AIM:Explore perspectives of adolescent and young adult (AYA) and parent stakeholders regarding their engagement in comparative effectiveness research (CER) evaluating cholesterol screening and treatment strategies for 17-21 year olds. METHODS:All nine AYAs and parent stakeholders participating in a 20-member panel of ...

journal_title：Journal of comparative effectiveness research

authors： Saunders T,Mackie TI,Shah S,Gooding H,de Ferranti SD,Leslie LK

更新日期：2016-08-01 00:00:00

abstract：:Aim: Indirect treatment comparisons are used when no direct comparison is available. Comparison networks should satisfy the transitivity assumption, that is, equal likelihood of treatment assignment for a given patient based on comparability of studies. Materials & methods: Seven criteria were evaluated across 18 rand...

journal_title：Journal of comparative effectiveness research

authors： Tremblay G,Westley T,Forsythe A,Pelletier C,Briggs A

更新日期：2019-11-01 00:00:00

abstract：AIM:To identify ongoing practices and opportunities for improving national comparative effectiveness research (CER) translation through dissemination and implementation (D&I) via NIH-funded Clinical and Translational Science Award (CTSA) institutions. MATERIALS & METHODS:Key informant interviews were conducted with 18...

journal_title：Journal of comparative effectiveness research

authors： Morrato EH,Concannon TW,Meissner P,Shah ND,Turner BJ

更新日期：2013-03-01 00:00:00

abstract：:Aim: To evaluate the patterns of cancer patients-assessed quality of outpatient care in the USA. Materials & methods: Medical Expenditure Panel Survey datasets for the years 2011, 2013, 2015 and 2017 were accessed and adult participants with a history of cancer diagnosis were reviewed. Participants' assessments of dif...

journal_title：Journal of comparative effectiveness research

authors： Abdel-Rahman O

更新日期：2020-09-01 00:00:00

abstract：:The intense competition that accompanied the growth of internet-based companies ushered in the era of 'big data' characterized by major innovations in processing of very large amounts of data and the application of advanced analytics including data mining and machine learning. Healthcare is on the cusp of its own era ...

journal_title：Journal of comparative effectiveness research

authors： Berger ML,Doban V

更新日期：2014-03-01 00:00:00

abstract：AIM:The importance of adjusting for cross-study heterogeneity when conducting network meta-analyses (NMAs) was demonstrated using a case study of biologic therapies for moderate-to-severe plaque psoriasis. METHODS:Bayesian NMAs were conducted for Psoriasis Area and Severity Index 90 response. Several covariates were c...

journal_title：Journal of comparative effectiveness research

authors： Cameron C,Hutton B,Druchok C,McElligott S,Nair S,Schubert A,Situ A,Varu A,Villacorta R

更新日期：2018-11-01 00:00:00

abstract：AIM:The incremental cost of peripheral orbital atherectomy system (OAS) plus balloon angioplasty (BA) versus BA-only for critical limb ischemia was estimated. MATERIALS & METHODS:A deterministic simulation model used clinical and healthcare utilization data from the CALCIUM 360° trial and current cost data. Incrementa...

journal_title：Journal of comparative effectiveness research

authors： Shammas NW,Boyes CW,Palli SR,Rizzo JA,Martinsen BJ,Kotlarz H,Mustapha JA

更新日期：2018-04-01 00:00:00

abstract：AIM:To provide an overview of thresholds for incremental cost-effectiveness ratios (ICERs) representing willingness-to-pay (WTP) across multiple countries and insights into exemptions pertaining to the ICER (e.g., cancer). To compare ICER thresholds to individual country's estimated ability-to-pay. MATERIALS & METHODS...

journal_title：Journal of comparative effectiveness research

authors： Schwarzer R,Rochau U,Saverno K,Jahn B,Bornschein B,Muehlberger N,Flatscher-Thoeni M,Schnell-Inderst P,Sroczynski G,Lackner M,Schall I,Hebborn A,Pugner K,Fehervary A,Brixner D,Siebert U

更新日期：2015-09-01 00:00:00

abstract：:Degenerative spine disorders are a significant cause of patient morbidity and are a prominent factor in healthcare costs in many countries. Pressure for healthcare cost control and the desire for improved outcomes have led to an expanding emphasis on evidence-based medicine methodologies in spine research. Determinati...

journal_title：Journal of comparative effectiveness research

authors： Lake WB,Brooks NP,Resnick DK

更新日期：2013-01-01 00:00:00

abstract：AIM:Develop an accessible exercise to engage underserved populations about research funding priorities; analyze the criteria they use to prioritize research; contrast these criteria to those currently used by Patient Centered Outcomes Research Institute (PCORI). MATERIALS & METHODS:Academic and community partners coll...

journal_title：Journal of comparative effectiveness research

authors： Cargill SS,Baker LL,Goold SD

更新日期：2017-07-01 00:00:00

abstract：:Comparative effectiveness research (CER) calls for substantial changes in the way clinical research is conducted, interpreted and practically applied in the USA, in order to produce useful clinical evidence. Departing from classic efficacy and effectiveness research, the evolving CER paradigm requires structural and s...

journal_title：Journal of comparative effectiveness research

authors： Greenfield S,Kaplan SH

更新日期：2012-05-01 00:00:00

abstract：AIM:To evaluate treatment patterns among elderly, newly diagnosed stage IV breast cancer patients receiving HER-2-targeted therapy. METHODS:Women aged 65+ with an incident diagnosis of stage IV breast cancer (index) and no history of other cancer were identified from 2006 to 2010 linked Surveillance, Epidemiology and ...

journal_title：Journal of comparative effectiveness research

authors： Lang K,Hao Y,Huang H,Lin I,Rogerio JW,Menzin J

更新日期：2014-09-01 00:00:00

abstract：:Clinical trial designs often fail to deliver data that jointly satisfy evolving demands of both regulatory and reimbursement authorities. We propose a new multi-tiered trial design to integrate efficacy and effectiveness, and address the evolving needs of authorities. The mixed randomized trial allocates patients firs...

journal_title：Journal of comparative effectiveness research

authors： Alsop J,Scott M,Archey W

更新日期：2016-11-01 00:00:00

abstract：:Evaluation of: Olanow CW, Kieburtz K, Odin P et al. Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study. Lancet Neurol. 13(2), 141-149 (2014). Levodopa-induced motor complications, including mot...

journal_title：Journal of comparative effectiveness research

authors： Guthikonda LN,Lyons KE,Pahwa R

更新日期：2014-07-01 00:00:00

abstract：AIMS:To develop principles for planning and conducting comparative effectiveness research (CER). METHODS:Beginning with a modified existing list of health technology assessment principles, we developed a set of CER principles using literature review, engagement of multiple experts and broad stakeholder feedback. RESU...

journal_title：Journal of comparative effectiveness research

authors： Luce BR,Drummond MF,Dubois RW,Neumann PJ,Jönsson B,Siebert U,Schwartz JS

更新日期：2012-09-01 00:00:00

abstract：:Aim: To perform cost-effectiveness analysis (CEA) and budget impact analysis (BIA) comparing stenting to standard medical treatment (SMT) for the management of deep venous outflow obstruction and leg ulcers from the Italian Healthcare Service perspective. Materials & methods: A Markov model was developed to project co...

journal_title：Journal of comparative effectiveness research

authors： Rognoni C,Lugli M,Maleti O,Tarricone R

更新日期：2020-07-01 00:00:00

abstract：:There is increasing attention in the US healthcare system on the delivery of high-quality care, an issue central to oncology. In the report 'Crossing the Quality Chasm', the Institute of Medicine identified six aims for improving healthcare quality: safe, effective, patient-centered, timely, efficient and equitable. T...

journal_title：Journal of comparative effectiveness research

authors： Broughman JR,Chen RC

更新日期：2016-05-01 00:00:00

abstract：:Choice-based conjoint (CBC) is used to understand how individuals develop preferences for decision alternatives. When decision alternatives can be described in terms of attributes, researchers want to determine the value respondents attach to various attribute levels. Popular in psychology, marketing, economics and ot...

journal_title：Journal of comparative effectiveness research

authors： Chitturi P,Carides A

更新日期：2020-01-01 00:00:00

abstract：:Rationale, aim & objective: The goal of this study was to examine the health and economic impacts related to increased utilization of the Duke Smoking Cessation Program resulting from the addition of two relatively new referral methods - Best Practice Advisory and Population Outreach. Materials & methods: In a compani...

journal_title：Journal of comparative effectiveness research

authors： Datta SK,Dennis PA,Davis JM

更新日期：2020-08-01 00:00:00

abstract：:The COVID-19 pandemic is revealing the unacceptable health disparities across New York City and in this country. The mortality rates of vulnerable and minority populations alone suggest a need to re-evaluate clinical decision making protocols, especially given the recently passed Emergency or Disaster Treatment Protec...

journal_title：Journal of comparative effectiveness research

authors： Caraccio C,White RS,Jotwani R

更新日期：2020-08-01 00:00:00