Abstract:
:Purified antibodies against guanylic acid and guanosine binding to RNA at guanosine residues were used to probe human lymphocyte preparations by indirect immunofluorescence. Neither antibody gave any banding pattern with metaphase chromosomes but both showed binding to specific sites in the interphase nuclei. Evidence presented indicates that these sites are guanosine residues on rDNA transcripts at the nucleolar organizer regions.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Iswari S,Krishnamurthy DS,Jacob TMdoi
10.1016/0014-5793(85)81043-7subject
Has Abstractpub_date
1985-09-23 00:00:00pages
296-300issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(85)81043-7journal_volume
189pub_type
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