Akt2 relaxes podocytes in chronic kidney disease.

Abstract:

:A signaling cascade is activated in podocytes to induce survival and cope with stress during advanced glomerular disease, a new study shows. The findings may also explain why the immunosuppressor sirolimus, an inhibitor of this pathway, can cause proteinuria in a subset of patients with chronic kidney disease (pages 1288–1296).

journal_name

Nat Med

journal_title

Nature medicine

authors

Reiser J

doi

10.1038/nm.3357

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

1212-3

issue

10

eissn

1078-8956

issn

1546-170X

pii

nm.3357

journal_volume

19

pub_type

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