Abstract:
:We report highly efficient continuous-wave terahertz (THz) photoconductive antenna based photomixer employing nano-gap electrodes in the active region. The tip-to-tip nano-gap electrode structure provides strong THz field enhancement and acts as a nano-antenna to radiate the THz wave generated in the active region of the photomixer. In addition, it provides good impedance matching to the THz planar antenna and exhibits a lower RC time constant, allowing more efficient radiation especially at the higher part of the THz spectrum. As a result, the output intensity of the photomixer with the new nano-gap electrode structure in the active region is two orders of magnitude higher than that of a photomixer with typical interdigitated electrodes. Significant improvement in the THz emission bandwidth was also observed. An efficient continuous wave THz source will greatly benefit compact THz system development for high resolution THz spectroscopy and imaging applications.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Tanoto H,Teng JH,Wu QY,Sun M,Chen ZN,Maier SA,Wang B,Chum CC,Si GY,Danner AJ,Chua SJdoi
10.1038/srep02824subject
Has Abstractpub_date
2013-10-08 00:00:00pages
2824issn
2045-2322pii
srep02824journal_volume
3pub_type
杂志文章abstract::Enzymatic gold nanoparticles (B-GNPs) have been synthesized using a natural anticancer agent bromelain (a cysteine protease) and these nanoparticles were used to bioconjugate Cisplatin (highly effective against osteosarcoma and lung cancer). Cisplatin bioconjugated bromelain encapsulated gold nanoparticles (B-C-GNPs) ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50215-y
更新日期:2019-09-25 00:00:00
abstract::The development of effective central nervous system (CNS) drugs has been hampered by the lack of robust strategies to mimic the blood-brain barrier (BBB) and cerebrovascular impairments in vitro. Recent technological advancements in BBB modeling using induced pluripotent stem cells (iPSCs) allowed to overcome some of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52213-6
更新日期:2019-11-05 00:00:00
abstract::Lymph node (LN) metastasis through the lymphatic network is a major route for cancer dissemination. Tumor cells reach the marginal sinuses of LNs via afferent lymphatic vessels (LVs) and form metastatic lesions that lead to distant metastasis. Thus, targeting of metastatic cells in the marginal sinuses could improve c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49386-5
更新日期:2019-09-13 00:00:00
abstract::The Late Pleistocene Campanian Ignimbrite (CI) super-eruption (Southern Italy) is the largest known volcanic event in the Mediterranean area. The CI tephra is widely dispersed through western Eurasia and occurs in close stratigraphic association with significant palaeoclimatic and Palaeolithic cultural events. Here we...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45940
更新日期:2017-04-06 00:00:00
abstract::Generally confinement size is considered to determine the dimensionality of nanostructures. While the exciton Bohr radius is used as a criterion to define either weak or strong confinement in optical experiments, the binding energy of confined excitons is difficult to measure experimentally. One alternative is to use ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40026
更新日期:2017-01-05 00:00:00
abstract::Sepsis is associated with thrombocytopenia and microvascular thrombosis. Studies have described platelets implication in this pathology but their kinetics of activation and behavior remain poorly known. We show in a mouse model of peritonitis, the appearance of platelet-rich thrombi in organ microvessels and organ dam...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31910-8
更新日期:2018-09-10 00:00:00
abstract::Type 2 Diabetes (T2D) is increasing but the effectiveness of large-scale diabetes screening programmes is debated. We assessed associations between coverage of a national cardiovascular and diabetes risk assessment programme in England (NHS Health Check) and detection and management of incident cases of non-diabetic h...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58033-3
更新日期:2020-01-27 00:00:00
abstract::Free standing, atomically thin transition metal dichalcogenides are a new class of ultralightweight nanoelectromechanical systems with potentially game-changing electro- and opto-mechanical properties, however, the energy dissipation pathways that fundamentally limit the performance of these systems is still poorly un...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05730-1
更新日期:2017-07-18 00:00:00
abstract::Impedance, or oscillometry, measurements of the respiratory system can generate information about the function of the respiratory system not possible with traditional spirometry. There are currently several instruments on the market using different perturbations. We have compared a new respiratory oscillometry instrum...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48039-x
更新日期:2019-08-12 00:00:00
abstract::Lung fibrosis is an unabated wound healing response characterized by the loss and aberrant function of lung epithelial cells. Herein, we report that extracellular Clusterin promoted epithelial cell apoptosis whereas intracellular Clusterin maintained epithelium viability during lung repair. Unlike normal and COPD lung...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15670-5
更新日期:2017-11-13 00:00:00
abstract::Transforming growth factor β-1 (TGFβ-1)-induced phosphorylation of transcription factors Smad2 and Smad3 plays a crucial role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). However, the molecular regulation of Smad2/Smad3 proteins stability remains a mystery. Here, we show that ubiquitin carboxyl-terminal...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep33116
更新日期:2016-09-08 00:00:00
abstract::Myosin X (Myo10), an actin-associated molecular motor, has a clear role in filopodia induction and cell migration in vitro, but its role in vivo in mammals is not well understood. Here, we investigate the role of Myo10 in melanocyte lineage and melanoma induction. We found that Myo10 knockout (Myo10KO) mice exhibit a ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28717-y
更新日期:2018-07-11 00:00:00
abstract::The present research relates to a fusion protein comprising a chromogenic blue ultramarine protein (UM) bound to a keratin-based peptide (KP). The KP-UM fusion protein explores UM chromogenic nature together with KP affinity towards hair. For the first time a fusion protein with a chromogenic nature is explored as a h...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50283-0
更新日期:2019-10-01 00:00:00
abstract::Plastic represents 60-80% of litter in the ocean. Degradation of plastic to small fragments leads to the formation of microplastics (MPs <5 mm) and nanoplastics (NPs <1 µm). One of the most widely used and representative plastics found in the ocean is polystyrene (PS). Among marine organisms, the immune system of biva...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65596-8
更新日期:2020-05-25 00:00:00
abstract::Anxiety and depression are thought to influence the genesis of ischemic diseases and not of valvular diseases, but little is known on the psychological profile of cardiac patients after surgery. Aim of this study was to investigate differences in disease experience and mood between patients undergoing cardiac rehabili...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32696-5
更新日期:2018-09-26 00:00:00
abstract::Heat stress threatens agriculture worldwide. Plants acquire heat stress tolerance through priming, which establishes stress memory during mild or severe transient heat stress. Such induced thermotolerance restructures metabolic networks and helps maintain metabolic homeostasis under heat stress. Here, we used an elect...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36484-z
更新日期:2019-01-17 00:00:00
abstract::Nanostructure based color filtering has been considered an attractive replacement for current colorant pigmentation in the display technologies, in view of its increased efficiencies, ease of fabrication and eco-friendliness. For such structural filtering, iridescence relevant to its angular dependency, which poses a ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04921
更新日期:2014-05-12 00:00:00
abstract::The strong adhesion of sub-micron sized particles to surfaces is a nuisance, both for removing contaminating colloids from surfaces and for conscious manipulation of particles to create and test novel micro/nano-scale assemblies. The obvious idea of using detergents to ease these processes suffers from a lack of contr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36443
更新日期:2016-11-03 00:00:00
abstract::Common genetic risk variants for colorectal cancer (CRC) have been identified at approximately 40 loci by genome-wide association studies (GWAS). We investigated the association of these risk variants by age at onset of CRC using case-only and case-control analysis. A total of 1,962 CRC cases and 2,668 controls from t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40644
更新日期:2017-01-13 00:00:00
abstract::Sea buckthorn (Hippophae Rhamnoides L.) is an important source of bioactive compounds such as: antioxidants, vitamins, fatty acids, amino acids, and minerals. Sea buckthorn leaves extracts have been proved to have anti-microbial, antioxidant, anti-inflammatory, and anti-viral properties. In this paper, the extraction ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48610-6
更新日期:2019-08-19 00:00:00
abstract::Hand, foot and mouth disease (HFMD) is a substantial burden throughout Asia, but the effects of temperature pattern on HFMD risk are inconsistent. To quantify the effect of temperature on HFMD incidence, Wuhan was chosen as the study site because of its high temperature variability and high HFMD incidence. Daily serie...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20318-z
更新日期:2018-01-31 00:00:00
abstract::We introduce a simple criterion to identify two-dimensional (2D) materials based on the comparison between experimental lattice constants and lattice constants mainly obtained from Materials-Project (MP) density functional theory (DFT) calculation repository. Specifically, if the relative difference between the two la...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05402-0
更新日期:2017-07-12 00:00:00
abstract::The last decade has seen an exponential expansion of interest in conjugating multiple enzymes of cascades in close proximity to each other, with the overarching goal being to accelerate the overall reaction rate. However, some evidence has emerged that there is no effect of proximity channeling on the reaction velocit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37034-3
更新日期:2019-01-24 00:00:00
abstract::Graphene plasmonics has become a highlighted research area due to the outstanding properties of deep-subwavelength plasmon excitation, long relaxation time, and electro-optical tunability. Although the giant conductivity of a graphene layer enables the low-dimensional confinement of light, the atomic scale of the laye...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43333
更新日期:2017-02-27 00:00:00
abstract::In "classic" biomedical research, diseases have usually been studied individually. The pioneering human disease network (HDN) studies jointly consider a large number of diseases, analyse their interconnections, and provide a more comprehensive description of diseases. However, most of the existing HDN studies are base...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21779-y
更新日期:2018-03-14 00:00:00
abstract::Diamond attracts considerable attention as a versatile and technologically useful material. For many demanding applications, such as recently emerged quantum optics and sensing, it is important to develop new routes for fabrication of diamond containing defects with specific optical, electronic and magnetic properties...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14789
更新日期:2015-10-05 00:00:00
abstract::Polymer derived ceramic (PDC) composite coatings were deposited on AISI 304 substrates using siloxane based preceramic polymer polymethlysilsquioxane (PMS) and ZrSi2 as active filler or Ag as passive filler. The tribological performance of the composite coatings was evaluated at room temperature and moderately high te...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33441-8
更新日期:2018-10-10 00:00:00
abstract::Core-shell nanoparticles often exhibit improved catalytic properties due to the lattice strain created in these core-shell particles. Herein, we demonstrate the synthesis of core-shell Au@Pd nanoparticles from their core-shell Au@Ag/Pd parents. This strategy begins with the preparation of core-shell Au@Ag nanoparticle...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11949
更新日期:2015-07-06 00:00:00
abstract::Recent advances in microfluidic cell cultures enable the construction of in vitro human skin models that can be used for drug toxicity testing, disease study. However, current in vitro skin model have limitations to emulate real human skin due to the simplicity of model. In this paper, we describe the development of '...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37471
更新日期:2016-11-21 00:00:00
abstract::Power induced wave collapse is one of the most fascinating phenomena in optics as it provides extremely high intensities, thus stimulating a range of nonlinear processes. For low power levels, propagation of beams in bulk media is dominated by diffraction, while above a certain threshold self-focusing is steadily enha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46060-8
更新日期:2019-07-02 00:00:00