Exploring TCGA Pan-Cancer data at the UCSC Cancer Genomics Browser.

abstract：:Cenozoic plant relicts are those groups that were once widespread in the Northern Hemisphere but are now restricted to some small isolated areas as a result of drastic climatic changes. They are good proxies to study how plants respond to climatic changes since their modern climatic requirements are known. Herein we l...

journal_title：Scientific reports

authors： Huang Y,Jacques FM,Su T,Ferguson DK,Tang H,Chen W,Zhou Z

更新日期：2015-09-15 00:00:00

abstract：:Adipose stromal cells (ASC) secrete various trophic factors that assist in the protection of neurons in a variety of neuronal death models. In this study, we tested the effects of human ASC conditional medium (ASC-CM) in human amyotrophic lateral sclerosis (ALS) transgenic mouse model expressing mutant superoxide dism...

journal_title：Scientific reports

authors： Fontanilla CV,Gu H,Liu Q,Zhu TZ,Zhou C,Johnstone BH,March KL,Pascuzzi RM,Farlow MR,Du Y

更新日期：2015-11-20 00:00:00

abstract：:Mammalian spermatogenesis is a classic adult stems cell-dependent process, supported by the self-renewal and differentiation of spermatogonial stem cells (SSCs). However, the identification of SSCs and elucidation of their behaviors in undisturbed testis has long been a big challenge. Here, we generated a knock-in mou...

journal_title：Scientific reports

authors： Sun F,Xu Q,Zhao D,Degui Chen C

更新日期：2015-12-01 00:00:00

abstract：:In contrast to annual plants, in perennial plants, the shoot apical meristem (SAM) can undergo seasonal transitions between dormancy and activity; understanding this transition is crucial for understanding growth in perennial plants. However, little is known about the molecular mechanisms of SAM development in trees. ...

journal_title：Scientific reports

authors： Xu H,Cao D,Chen Y,Wei D,Wang Y,Stevenson RA,Zhu Y,Lin J

更新日期：2016-02-02 00:00:00

abstract：:Human corneal endothelial cells (HCECs) easily become fibroblastic-like when cultured, rendering them unsuitable for tissue engineering of the cornea. Transforming growth factor β (TGF-β) could be a key factor in this phenomenon; however, TGF-β is also known to maintain the endothelium in a quiescent state in vivo. Th...

journal_title：Scientific reports

authors： Beaulieu Leclerc V,Roy O,Santerre K,Proulx S

更新日期：2018-03-13 00:00:00

abstract：:The existing molecular cloning methods are often limited by the availability of suitable restriction sites. It is still a challenge for simultaneous cloning of multiple fragments into different sites of a single vector. Here we developed a novel method named improved overlap extension PCR (IOEP) for restriction enzyme...

journal_title：Scientific reports

authors： Guo W,Xie B,Jiang M,Zhu XJ,Qiu M,Dai ZM

更新日期：2019-10-30 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Yu YS,Wang MC,Huang X

更新日期：2018-03-19 00:00:00

abstract：:Tau is a microtubule-associated protein whose C-terminal domain consisting of four repeat regions R1, R2, R3 and R4 binds to microtubules to stabilize them. In several neurodegenerative diseases, tau detaches from microtubules to form insoluble aggregates leading to tauopathy. Microtubules are made up of αβ tubulin su...

journal_title：Scientific reports

authors： Bhandare VV,Kumbhar BV,Kunwar A

更新日期：2019-07-25 00:00:00

abstract：:We measured the magnitude of submarine fresh groundwater discharge (SFGD) and associated nutrient inputs to Jocheon harbor, on Jeju Island, Korea, during four sampling periods, in order to determine the link between SFGD and Ulva sp. green tide development. Good correlations among salinity, 222Rn, and dissolved inorga...

journal_title：Scientific reports

authors： Kwon HK,Kang H,Oh YH,Park SR,Kim G

更新日期：2017-07-24 00:00:00

abstract：:The phase behaviour of a system composed of amino acid-based surfactant (sodium N-lauroylsarcosinate hydrate), 1-decanol and deionised water was investigated for vesicle formation. Changing the molar ratio of the amphiphiles, two important aggregate structures were observed in the aqueous corner of the phase diagram. ...

journal_title：Scientific reports

authors： Akter N,Radiman S,Mohamed F,Rahman IA,Reza MI

更新日期：2011-01-01 00:00:00

abstract：:Deprivation of maternal care during early development markedly affects emotional development, but the underlying neuromolecular mechanisms are not fully understood. In a mouse model of disrupted mother-infant relationship, early weaning causes long-term impacts on pups to exhibit increased corticosterone secretion, an...

journal_title：Scientific reports

authors： Kikusui T,Kanbara N,Ozaki M,Hirayama N,Ida K,Tokita M,Tanabe N,Mitsuyama K,Abe H,Yoshida M,Nagasawa M,Mogi K

更新日期：2019-03-08 00:00:00

abstract：:Red mud as a waste material is produced in large quantities by the aluminum industry. Heat activation has been used to enhance sorption capacity of red mud for its beneficial reuse as an effective sorbent. In this study, heat-activated red mud (HARM) was investigated for its Cd(II) sorption capacity under various proc...

journal_title：Scientific reports

authors： Yang T,Sheng L,Wang Y,Wyckoff KN,He C,He Q

更新日期：2018-09-10 00:00:00

abstract：:The extraction of renewable energy resources particularly from earth abundant materials has always been a matter of significance in industrial products. Herein, we report a novel simultaneous extraction of nano-silicon with activated carbons (nano-Si@ACs) from rice husk (RH) by chemical activation method. As-extracted...

journal_title：Scientific reports

authors： Ahmad W,Bahrani MR,Yang Z,Khan J,Jing W,Jiang F,Chu L,Liu N,Li L,Gao Y

更新日期：2016-12-21 00:00:00

abstract：:Sterile liver inflammation and fibrosis are associated with many liver disorders of different etiologies. Both type 1 and type 2 inflammatory responses have been reported to contribute to liver pathology. However, the mechanisms controlling the balance between these responses are largely unknown. Natural killer T (NKT...

journal_title：Scientific reports

authors： Nilsson J,Hörnberg M,Schmidt-Christensen A,Linde K,Nilsson M,Carlus M,Erttmann SF,Mayans S,Holmberg D

更新日期：2020-12-11 00:00:00

abstract：:Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics. Paclitaxel-loaded genipin-crosslinked gelatin microspheres (PTX-GP-MS) a...

journal_title：Scientific reports

authors： De Clercq K,Xie F,De Wever O,Descamps B,Hoorens A,Vermeulen A,Ceelen W,Vervaet C

更新日期：2019-10-16 00:00:00

abstract：:Nano/microfibrous structure can induce high cellular activities because of the topological similarity of the extracellular matrix, and thus, are widely used in various tissue regenerative materials. However, the fabrication of a bioceramic (high weight percent)-based 3D microfibrous structure is extremely difficult be...

journal_title：Scientific reports

authors： Kim M,Yun HS,Kim GH

更新日期：2017-06-09 00:00:00

abstract：:4D flow MRI enables quantitative assessment of helical flow. Current methods are susceptible to noise. To evaluate helical flow patterns in healthy volunteers and patients with bicuspid aortic valves (BAV) at 1.5 T and 3 T using pressure-based helix-extraction in 4D flow MRI. Two intraindividual 4D flow MRI examinatio...

journal_title：Scientific reports

authors： Ebel S,Dufke J,Köhler B,Preim B,Behrendt B,Riekena B,Jung B,Stehning C,Kropf S,Grothoff M,Gutberlet M

更新日期：2020-02-19 00:00:00

abstract：:Detailed measurement of cell phenotype information from digital fluorescence images has the potential to greatly advance biomedicine in various disciplines such as patient diagnostics or drug screening. Yet, the complexity of cell conformations presents a major barrier preventing effective determination of cell bounda...

journal_title：Scientific reports

authors： Arce SH,Wu PH,Tseng Y

更新日期：2013-01-01 00:00:00

abstract：:Pathologic diagnoses mainly depend on visual scoring by pathologists, a process that can be time-consuming, laborious, and susceptible to inter- and/or intra-observer variations. This study proposes a novel method to enhance pathologic scoring of renal allograft rejection. A fully automated system using a convolutiona...

journal_title：Scientific reports

authors： Kim YG,Choi G,Go H,Cho Y,Lee H,Lee AR,Park B,Kim N

更新日期：2019-03-26 00:00:00

abstract：:We have employed a model system, inspired by SNARE proteins, to facilitate membrane fusion between Giant Unilamellar Vesicles (GUVs) and Large Unilamellar Vesicles (LUVs) under physiological conditions. In this system, two synthetic lipopeptide constructs comprising the coiled-coil heterodimer-forming peptides K4, (KI...

journal_title：Scientific reports

authors： Mora NL,Boyle AL,Kolck BJV,Rossen A,Pokorná Š,Koukalová A,Šachl R,Hof M,Kros A

更新日期：2020-02-20 00:00:00

abstract：:Etomoxir (ETO) is a widely used small-molecule inhibitor of fatty acid oxidation (FAO) through its irreversible inhibitory effects on the carnitine palmitoyl-transferase 1a (CPT1a). We used this compound to evaluate the role of fatty acid oxidation in rapidly proliferating T cells following costimulation through the C...

journal_title：Scientific reports

authors： O'Connor RS,Guo L,Ghassemi S,Snyder NW,Worth AJ,Weng L,Kam Y,Philipson B,Trefely S,Nunez-Cruz S,Blair IA,June CH,Milone MC

更新日期：2018-04-19 00:00:00

abstract：:A variety of post-translational modifications of Plasmodium falciparum proteins, including phosphorylation and ubiquitination, are shown to have key regulatory roles during parasite development. NEDD8 is a ubiquitin-like modifier of cullin-RING E3 ubiquitin ligases, which regulates diverse cellular processes. Although...

journal_title：Scientific reports

authors： Bhattacharjee M,Adhikari N,Sudhakar R,Rizvi Z,Das D,Palanimurugan R,Sijwali PS

更新日期：2020-11-19 00:00:00

abstract：:A central challenge in designing and administering effective anticoagulants is achieving the proper therapeutic window and dosage for each patient. The Hill coefficient, nH, which measures the steepness of a dose-response relationship, may be a useful gauge of this therapeutic window. We sought to measure the Hill coe...

journal_title：Scientific reports

authors： Chang JB,Quinnies KM,Realubit R,Karan C,Rand JH,Tatonetti NP

更新日期：2016-07-21 00:00:00

abstract：:The goal of the current study was to develop an asymmetric guided bone regeneration (GBR) membrane benefiting from curcumin and aspirin. The membrane was prepared using electrospinning technique and then was physic-chemically characterized by the conventional methods. The release profile of aspirin from the prepared m...

journal_title：Scientific reports

authors： Ghavimi MA,Bani Shahabadi A,Jarolmasjed S,Memar MY,Maleki Dizaj S,Sharifi S

更新日期：2020-10-23 00:00:00

abstract：:We investigated the dynamics of the interaction between spin-polarized photo-created carriers and Mn ions on InGaAs/GaAs: Mn structures. The carriers are confined in an InGaAs quantum well and the Mn ions come from a Mn delta-layer grown at the GaAs barrier close to the well. Even though the carriers and the Mn ions a...

journal_title：Scientific reports

authors： Balanta MA,Brasil MJ,Iikawa F,Mendes UC,Brum JA,Danilov YA,Dorokhin MV,Vikhrova OV,Zvonkov BN

更新日期：2016-04-15 00:00:00

abstract：:Black phosphorus (BP) has recently been rediscovered as a new and interesting two-dimensional material due to its unique electronic and optical properties. Here, we study the linear and nonlinear optical properties of BP flakes. We observe that both the linear and nonlinear optical properties are anisotropic and can b...

journal_title：Scientific reports

authors： Li D,Jussila H,Karvonen L,Ye G,Lipsanen H,Chen X,Sun Z

更新日期：2015-10-30 00:00:00

abstract：:Voltage gated sodium channels are key players in aberrant pain signaling and sensitization of nociceptors after peripheral nerve injury. The extent to which sodium channel activity after injury contributes to synaptic transmission at the first pain synapse however remains unclear. To investigate the effect of axotomy ...

journal_title：Scientific reports

authors： Vysokov N,McMahon SB,Raouf R

更新日期：2019-09-09 00:00:00

abstract：:The presence of non-poplar extracts, cutin, and wax layer in the wheat straw outer surface (WOS) greatly limit its application in bio-composite preparation. In this study, a dielectric-barrier-discharge plasma using water vapor as feeding gas was used to fast modify the WOS. The morphology, free radical concentrations...

journal_title：Scientific reports

authors： Chen W,Xu Y,Shi S,Cao Y,Chen M,Zhou X

更新日期：2018-02-02 00:00:00

abstract：:The goal of this study was to evaluate the risk of developing acute myocardial infarction (AMI) following retinal vein occlusion (RVO). A retrospective cohort study was performed from the National Health Insurance Service and comprised 1,025,340 random subjects who were followed from 2002 to 2013. Patients with RVO in...

journal_title：Scientific reports

authors： Rim TH,Han JS,Oh J,Kim DW,Kang SM,Chung EJ

更新日期：2016-02-29 00:00:00

abstract：:Strongly coupled quantum dot-cavity systems provide a non-linear configuration of hybridized light-matter states with promising quantum-optical applications. Here, we investigate the coherent interaction between strong laser pulses and quantum dot-cavity polaritons. Resonant excitation of polaritonic states and their ...

journal_title：Scientific reports

authors： Dory C,Fischer KA,Müller K,Lagoudakis KG,Sarmiento T,Rundquist A,Zhang JL,Kelaita Y,Vučković J

更新日期：2016-04-26 00:00:00