Visual hallucinations during duloxetine treatment in a patient with major depressive disorder.

Abstract:

:Duloxetine is a serotonin-noradrenaline reuptake inhibitor that is effective in the treatment of major depressive disorder (MDD) and chronic pain. The safety of duloxetine has been shown by many previous studies. We report a patient who experienced visual hallucinations after taking duloxetine. The patient experienced insomnia and chronic somatic pain. He began taking duloxetine after a diagnosis of MDD and developed visual hallucinations after the duloxetine dose was increased. The hallucinations disappeared after the duloxetine dose was decreased and then stopped; the dose of quetiapine was increased as an alternative. The specific cause of the duloxetine-induced hallucinations is unclear. In addition to other prescription medications and possible interactions with duloxetine, increasing dopamine by blocking noradrenaline transporters or serotonergic neurotransmission function may contribute to the occurrence of hallucinations.

journal_name

Clin Neuropharmacol

authors

Tomita T,Yasui-Furukori N,Kaneko S

doi

10.1097/WNF.0b013e3182a124cb

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

175-6

issue

5

eissn

0362-5664

issn

1537-162X

pii

00002826-201309000-00009

journal_volume

36

pub_type

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