Interplay of cytoskeletal activity and lipid phase stability in dynamic protein recruitment and clustering.

abstract：:Discriminating between inherited and non-inherited sporadic hearing loss is challenging. Here, we attempted to delineate genetic inheritance in simplex cases of severe-to-profound congenital hearing loss in Korean children. Variations in SLC26A4 and GJB2 in 28 children with bilateral severe-to-profound non-syndromic h...

journal_title：Scientific reports

authors： Jung J,Lee JS,Cho KJ,Yu S,Yoon JH,Yung Gee H,Choi JY

更新日期：2017-04-06 00:00:00

abstract：:Ethnic admixtures may interfere with the definition of type 1 diabetes (T1D) risk determinants. The role of HLA, PTPN22, INS-VNTR, and CTLA4 in T1D predisposition was analyzed in Brazilian T1D patients (n = 915), with 81.7% self-reporting as white and 789 controls (65.6% white). The results were corrected for populati...

journal_title：Scientific reports

authors： Gomes KF,Santos AS,Semzezem C,Correia MR,Brito LA,Ruiz MO,Fukui RT,Matioli SR,Passos-Bueno MR,Silva ME

更新日期：2017-03-06 00:00:00

abstract：:The importance of microbial natural products has been widely demonstrated in the search for new antibiotics. However, the functional role of microbial metabolites in nature remains to be deciphered. Several natural products are known to mediate microbial interactions through metabolic exchange. One approach to investi...

journal_title：Scientific reports

authors： Caraballo-Rodríguez AM,Dorrestein PC,Pupo MT

更新日期：2017-07-14 00:00:00

abstract：:High-throughput single-stranded DNA sequencing (ssDNA-seq) of cell-free DNA from plasma and other bodily fluids is a powerful method for non-invasive prenatal testing, and diagnosis of cancers and other diseases. Here, we developed a facile ssDNA-seq method, which exploits a novel template-switching activity of thermo...

journal_title：Scientific reports

authors： Wu DC,Lambowitz AM

更新日期：2017-08-21 00:00:00

abstract：:Daily music experience involves synchronizing movements in time with a perceived periodic beat. It has been established for over a century that beat synchronization is less stable for the visual than for the auditory modality. This auditory advantage of beat synchronization gives rise to the hypotheses that the neural...

journal_title：Scientific reports

authors： Gan L,Huang Y,Zhou L,Qian C,Wu X

更新日期：2015-07-07 00:00:00

abstract：:Nitrification directly contributes to the ammonia removal in sponges, and it plays an indispensable role in sponge-mediated nitrogen cycle. Previous studies have demonstrated genomic evidences of nitrifying lineages in the sponge Theonella swinhoei. However, little is known about the transcriptional activity of nitrif...

journal_title：Scientific reports

authors： Feng G,Sun W,Zhang F,Karthik L,Li Z

更新日期：2016-04-26 00:00:00

abstract：:The Casimir force exerted on a gold dipolar nanoparticle by a finite-thickness slab of the natural hyperbolic material namely, the ortorhombic crystalline modification of boron nitride, is investigated. The main contribution to the force originates from the TM-polarized waves, for frequencies at which the parallel and...

journal_title：Scientific reports

authors： Nefedov IS,Rubi JM

更新日期：2020-10-08 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Kim S,Moon M,Kwak M,Lee B,Chang YK

更新日期：2019-06-05 00:00:00

abstract：:Sesquiterpene lactones (STL) are a subclass of isoprenoids with many known bioactivities frequently found in the Asteraceae family. In recent years, remarkable progress has been made regarding the biochemistry of STL, and today the biosynthetic pathway of the core backbones of many STLs has been elucidated. Consequent...

journal_title：Scientific reports

authors： Frey M,Klaiber I,Conrad J,Bersch A,Pateraki I,Ro DK,Spring O

更新日期：2019-10-04 00:00:00

abstract：:Rather than the conventional concept of viewing conductive carbon black (CB) to be chemically inert in microbial electrochemical cells (MECs), here we confirmed the redox activity of CB for its feasibility as an electron sink in the microbial battery (MB). Acting as the cathode of a MB, the solid-state CB electrode sh...

journal_title：Scientific reports

authors： Zhang X,Guo K,Shen D,Feng H,Wang M,Zhou Y,Jia Y,Liang Y,Zhou M

更新日期：2017-08-01 00:00:00

abstract：:A generation of reactive oxygen species (ROS) from TiO2 under solar light has been long sought since the ROS can disinfect organic pollutants. We found that newly developed crystalline/amorphous reduced TiO2 (rTiO2) that has low energy bandgap can effectively generate ROS under solar light and successfully remove a bl...

journal_title：Scientific reports

authors： Kim Y,Hwang HM,Wang L,Kim I,Yoon Y,Lee H

更新日期：2016-04-28 00:00:00

abstract：:Microbial induced calcite precipitation (MICP) based on ureolysis has a high potential for many applications, e.g. restoration of construction materials. The gram-positive bacterium Sporosarcina pasteurii is the most commonly used microorganism for MICP due to its high ureolytic activity. However, Sporosarcina pasteur...

journal_title：Scientific reports

authors： Lapierre FM,Schmid J,Ederer B,Ihling N,Büchs J,Huber R

更新日期：2020-12-31 00:00:00

abstract：:Deregulated IGF-1R-AKT signaling influences multiple nodes of cancer cell physiology and assists in migration, metastasis and acquirement of radio/chemoresistance. Enrichment of cancer stem cells (CSC) positively correlates with radio/chemoresistance development in various malignancies. It is unclear though, how IGF-1...

journal_title：Scientific reports

authors： Singh RK,Dhadve A,Sakpal A,De A,Ray P

更新日期：2016-11-07 00:00:00

abstract：:CD4(+)CD25(+) T cells are critical for maintenance of immunologic self-tolerance. We measured the number of CD4(+)CD25(+) cells in the patients with primary malignant hypertension related kidney injury, to explore the molecular pathogenesis of this disease. We selected 30 patients with primary malignant hypertension r...

journal_title：Scientific reports

authors： Huang H,Luo Y,Liang Y,Long X,Peng Y,Liu Z,Wen X,Jia M,Tian R,Bai C,Li C,He F,Lin Q,Wang X,Dong X

更新日期：2016-06-09 00:00:00

abstract：:Since its first implementation in otolaryngological surgery nearly a century ago, the surgical microscope has improved the accuracy and the safety of microsurgeries. However, the microscope shows only a magnified surface view of the surgical region. To overcome this limitation, either optical coherence tomography (OCT...

journal_title：Scientific reports

authors： Lee D,Lee C,Kim S,Zhou Q,Kim J,Kim C

更新日期：2016-10-12 00:00:00

abstract：:Specific HPV genotypes have been recognized as risk factors inducing head and neck cancers (HNC). The aim of this study was to validate a real-time PCR assay to detect accurately High Risk HPV DNA in Formalin Fixed Paraffin Embedded (FFPE) and oral cytobrush samples and compare the results with conventional PCR. Repea...

journal_title：Scientific reports

authors： Harlé A,Guillet J,Thomas J,Sastre-Garau X,Rouyer M,Ramacci C,Gilson P,Dubois C,Dolivet G,Leroux A,Salleron J,Merlin JL

更新日期：2018-07-27 00:00:00

abstract：:Lower corrected calcium (cCa) levels are associated with a better prognosis among incident dialysis patients. However, cCa frequently overestimates ionized calcium (iCa) levels. The prognostic importance of the true calcium status defined by iCa remains to be revealed. We conducted a retrospective cohort study of inci...

journal_title：Scientific reports

authors： Yamaguchi S,Hamano T,Doi Y,Oka T,Kajimoto S,Kubota K,Yasuda S,Shimada K,Matsumoto A,Hashimoto N,Sakaguchi Y,Matsui I,Isaka Y

更新日期：2020-03-10 00:00:00

abstract：:Ocean uptake of anthropogenic CO2 reduces pH and saturation state of calcium carbonate materials of seawater, which could reduce the calcification rate of some marine organisms, triggering a negative feedback on the growth of atmospheric CO2. We quantify the effect of this CO2-calcification feedback by conducting a se...

journal_title：Scientific reports

authors： Zhang H,Cao L

更新日期：2016-02-03 00:00:00

abstract：:Extremely low frequency magnetic fields (ELF-MF) could be an alternative neuroprotective approach for ischemic stroke because preclinical studies have demonstrated their effects on the mechanisms underlying ischemic damage. The purpose of this open-label, one arm, dose-escalation, exploratory study is to evaluate the ...

journal_title：Scientific reports

authors： Capone F,Liberti M,Apollonio F,Camera F,Setti S,Cadossi R,Quattrocchi CC,Di Lazzaro V

更新日期：2017-09-22 00:00:00

abstract：:Mask ventilation and coughing during oro-tracheal suctioning produce aerosols that enhance nosocomial transmission of respiratory infections. We examined the extent of exhaled air dispersion from a human-patient-simulator during mask ventilation by different groups of healthcare workers and coughing bouts. The simulat...

journal_title：Scientific reports

authors： Chan MTV,Chow BK,Lo T,Ko FW,Ng SS,Gin T,Hui DS

更新日期：2018-01-09 00:00:00

abstract：:Hesperiidae is one of the largest families of butterflies. Our knowledge of the higher systematics on hesperiids from China is still very limited. We infer the phylogenetic relationships of the subfamilies of Chinese skippers based on three mitochondrial genes (cytochrome b (Cytb), the NADH dehydrogenase subunit 1 (ND...

journal_title：Scientific reports

authors： Yuan X,Gao K,Yuan F,Wang P,Zhang Y

更新日期：2015-06-10 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Neergaard KD,Luo J,Huang CR

更新日期：2020-01-14 00:00:00

abstract：:We delineate the four principal surface plasmon polariton coupling and interaction mechanisms in subwavelength gratings, and demonstrate their significant roles in shaping the optical response of plasmonic gratings. Within the framework of width-graded metal-insulator-metal nano-gratings, electromagnetic field confine...

journal_title：Scientific reports

authors： Shayegannia M,Montazeri AO,Dixon K,Prinja R,Kazemi-Zanjani N,Kherani NP

更新日期：2021-01-12 00:00:00

abstract：:YPEL3 that induces cellular senescence in both normal and tumour cells of humans may show altered expression under the influence of incidental mutations. In this study, we proposed the first structure of Native YPEL3 protein and its five possible deleterious mutants-V40M, C61Y, G98R, G108S, and A131T and predicted the...

journal_title：Scientific reports

authors： Singh A,Thakur M,Singh SK,Sharma LK,Chandra K

更新日期：2020-09-17 00:00:00

abstract：:Ocular graft-versus-host disease (GVHD) is a common complication after hematopoietic stem cell transplantation (HSCT). Here we compared the diagnostic rates of ocular GVHD, including its severity, prognosis and the agreement, obtained using three grading scales: the National Institutes of Health (NIH) eye score, Japan...

journal_title：Scientific reports

authors： Tatematsu Y,Ogawa Y,Abe T,Kamoi M,Uchino M,Saijo-Ban Y,Yaguchi S,Mukai S,Mori T,Okamoto S,Tsubota K

更新日期：2014-10-22 00:00:00

abstract：:Landscape's spatial structure has vast implications for the dynamics and distribution of species populations and ecological communities. However, the characterization of the structure of spatial networks has not received nearly as much attention as networks of species interactions counterparts. Recent experiments show...

journal_title：Scientific reports

authors： Gilarranz LJ

更新日期：2020-05-26 00:00:00

abstract：:Asbestos is a potent carcinogen associated with malignant mesothelioma and lung cancer but its carcinogenic mechanisms are still poorly understood. Asbestos toxicity is ascribed to its particular physico-chemical characteristics, and one of them is the presence of and ability to adsorb iron, which may cause an alterat...

journal_title：Scientific reports

authors： Pascolo L,Gianoncelli A,Schneider G,Salomé M,Schneider M,Calligaro C,Kiskinova M,Melato M,Rizzardi C

更新日期：2013-01-01 00:00:00

abstract：:Cnidarians, in general, are long-lived organisms and hence may repeatedly encounter common pathogens during their lifespans. It remains unknown whether these early diverging animals possess some type of immunological reaction that strengthens the defense response upon repeated infections, such as that described in mor...

journal_title：Scientific reports

authors： Brown T,Rodriguez-Lanetty M

更新日期：2015-12-02 00:00:00

abstract：:The development of bulk, three-dimensional (3D), macroporous polymers with high permeability, large surface area and large volume is highly desirable for a range of applications in the biomedical, biotechnological and environmental areas. The experimental techniques currently used are limited to the production of smal...

journal_title：Scientific reports

authors： Savina IN,Ingavle GC,Cundy AB,Mikhalovsky SV

更新日期：2016-02-17 00:00:00

abstract：:Crop wild relatives are valuable resources for future genetic improvement. Here, we report the de novo genome assembly of Musa itinerans, a disease-resistant wild banana relative in subtropical China. The assembled genome size was 462.1 Mb, covering 75.2% of the genome (615.2Mb) and containing 32, 456 predicted protei...

journal_title：Scientific reports

authors： Wu W,Yang YL,He WM,Rouard M,Li WM,Xu M,Roux N,Ge XJ

更新日期：2016-08-17 00:00:00