Abstract:
BACKGROUND:Stroke continues to be a major public health concern in the United States. Motor recovery in the post-acute stages of stroke is possible due to neuroplasticity, or the capacity of the brain to reorganize. OBJECTIVE:This case study tracks neuroplastic and motor change in a subject with severe hemiparesis following an extensive middle cerebral artery stroke. He had absence of ipsilesional motor evoked potentials in early evaluations. This report is unique in that the duration of follow-up evaluation extends nearly 2 years, with evaluations being performed at 7, 9, 10, 13, 20, and 21 months post-stroke. METHODS:At each evaluation we used transcranial magnetic stimulation to track neuroplastic change and the Fugl-Meyer Assessment and the Wolf Motor Function Test to evaluate upper extremity motor performance. RESULTS:The contralesional hemisphere showed dynamic change throughout the study period. In contrast, the ipsilesional hemisphere demonstrated notable change only between 13 and 21 months post-stroke, with the most dramatic change occurring between 20 and 21 months post-stroke. Motor performance generally improved throughout the study period. CONCLUSIONS:Our findings demonstrate that substantial neuroplasticity-mediated motor recovery can occur nearly 2 years after stroke in an individual with severe post-stroke motor impairment.
journal_name
NeuroRehabilitationjournal_title
NeuroRehabilitationauthors
Chelette KC,Carrico C,Nichols L,Sawaki Ldoi
10.3233/NRE-130968subject
Has Abstractpub_date
2013-01-01 00:00:00pages
385-9issue
3eissn
1053-8135issn
1878-6448pii
N711865K83270148journal_volume
33pub_type
杂志文章abstract:BACKGROUND:Pisa syndrome (PS) is a clinical condition frequently associated with Parkinson's disease (PD). It is characterized by a trunk lateral flexion higher than 10 degrees and reversible when lying. One pathophysiological hypothesis is the altered verticality perception, due to a somatosensory impairment. Osteopat...
journal_title:NeuroRehabilitation
pub_type: 杂志文章,随机对照试验
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更新日期:2020-01-01 00:00:00
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journal_title:NeuroRehabilitation
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pub_type: 杂志文章
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doi:
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章,随机对照试验
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journal_title:NeuroRehabilitation
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
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更新日期:2013-01-01 00:00:00
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更新日期:2018-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2003-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:NeuroRehabilitation
pub_type: 杂志文章
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